What is Tirzepatide
Tirzepatide is a new injectable medication that was recently approved by the FDA for the treatment of overweight or obesity. the weight loss injection is marketed under the brand name Mounjaro
Its primary function is to promote weight loss by increasing satiety and reducing hunger. It does this by mimicking the action of the hormone leptin, which is responsible for regulating energy intake and expenditure.
In clinical trials, Tirzepatide was shown to induce significant weight loss, with patients losing an average of 5% of their body weight after 16 weeks of treatment. Tirzepatide also resulted in improvements in blood sugar control and lipid levels.
These effects are thought to be mediated by Tirzepatide’s ability to reduce inflammation and improve insulin sensitivity. Overall, Tirzepatide represents a promising new option for the treatment of obesity and related conditions.
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Who Makes Tirzepatide?
The drug is manufactured by Eli Lilly and Company
What is Mounjaro
Mounjaro is the brand name of the drug Tirzepatide
How Does Tirzepatide Work?
Tirzepatide is a novel peptide that selectively activates the GLP-1 receptor. It is being developed as a once-weekly injection to improve glycemic control in patients with type 2 diabetes mellitus. Tirzepatide has completed Phase III clinical trials and is currently under review by the FDA for approval. The drug is being developed by Eli Lilly and Company.
Tirzepatide is a peptide that consists of 26 amino acids. It is produced using recombinant DNA technology in E. coli bacteria. The amino acid sequence of tirzepatide is identical to the human GLP-1 receptor agonist peptide sequence. tirzepatide has high affinity and selectivity for the GLP-1 receptor and potentiates cAMP accumulation in cells expressing the human GLP-1 receptor.
In preclinical studies, tirzepatide improved glucose tolerance, increased insulin secretion, and reduced body weight in animal models of type 2 diabetes mellitus. In clinical trials, tirzepatide monotherapy improved fasting plasma glucose, postprandial plasma glucose, and glycosylated hemoglobin (HbA1c) levels in patients with type 2 diabetes.
Where Can I Buy Mounjaro or Tirzepatide?
The weight loss injection is not available yet. It cannot be purchased over the counter. It must be prescribed by your doctor.
What is Similar to Mounjaro or Tirzepatide?
There are a few similar drugs for weight loss that are delivered by injection or taken orally that work in a similar way to Mounjaro / Tirzepatide?
- Wegovy – Wegovy was developed by the Danish pharmaceutical company Novo Nordisk. It provides a synthetic version of a gut hormone that reduces appetite. The generic form of Wegovy is called Semaglutide.
- SkinnyJab – SkinnyJab is a weight loss injection containing Saxenda also know as Liraglutide
- Phentermine – an oral capsule that can help reduce appetite.
- Qsymia is a weight loss medication that provides a combination of Phentermine and Topiramate.