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Diego's Colleagues
Bryan Chen
Stanford University
Dan Kaganovich
Weizmann Institute
Daniel Meyer
Stanford University
Ofir Goldberger
Stanford University
Ron Geller
Stanford University
Sheila Jaswal
Stanford University
Veronique Albanese
Stanford University
Stanford University
Postdoc
Published by Diego Adhemar Jaitin
Kalie et al JBC 2008
Upregulation of a small subset of genes drives type I interferon-induced antiviral memory.
An interferon alpha2 mutant optimized by phage display for IFNAR1 binding confers specifically enhanced antitumor activities.
Variations in the unstructured C-terminal tail of interferons contribute to differential receptor binding and biological activity.
Inquiring into the differential action of interferons (IFNs): an IFN-alpha2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-beta.
Mutational analysis of the IFNAR1 binding site on IFNalpha2 reveals the architecture of a weak ligand-receptor binding-site.