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Papers authored by Zheng BJ

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Differential susceptibility of different cell lines to swine-origin influenza A H1N1, seasonal human influenza A H1N1, and avian influenza A H5N1 viruses.

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Li IW, Chan KH, To KW, Wong SS, Ho PL, Lau SK, Woo PC, Tsoi HW, Chan JF, Cheng VC, Zheng BJ, Chen H, and Yuen KY

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 46(4):325-30, 2009 Dec - Who cited this? | PubMed ID: 19801200 | Fulltext

Recombinant receptor-binding domain of SARS-CoV spike protein expressed in mammalian, insect and E. coli cells elicits potent neutralizing antibody and protective immunity.

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Du L, Zhao G, Chan CC, Sun S, Chen M, Liu Z, Guo H, He Y, Zhou Y, Zheng BJ, and Jiang S

Virology 393(1):144-50, 2009 Oct 10 - Who cited this? | PubMed ID: 19683779 | Fulltext

Leptin signaling protects NK cells from apoptosis during development in mouse bone marrow.

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Lo CK, Lam QL, Yang M, Ko KH, Sun L, Ma R, Wang S, Xu H, Tam S, Wu CY, Zheng BJ, and Lu L

Cellular & molecular immunology 6(5):353-60, 2009 Oct - Who cited this? | PubMed ID: 19887048 | Fulltext

Severe acute respiratory syndrome coronavirus nucleocapsid protein does not modulate transcription of the human FGL2 gene.

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Siu KL, Chan CP, Chan C, Zheng BJ, and Jin DY

The Journal of general virology 90(Pt 9):2107-13, 2009 Sep - Who cited this? | PubMed ID: 19423547 | Fulltext

Functional dissection of an IFN-alpha/beta receptor 1 promoter variant that confers higher risk to chronic hepatitis B virus infection.

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Zhou J, Huang JD, Poon VK, Chen DQ, Chan CC, Ng F, Guan XY, Watt RM, Lu L, Yuen KY, and Zheng BJ

Journal of hepatology 51(2):322-32, 2009 Aug - Who cited this? | PubMed ID: 19501422 | Fulltext

Antigenicity and immunogenicity of SARS-CoV S protein receptor-binding domain stably expressed in CHO cells.

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Du L, Zhao G, Li L, He Y, Zhou Y, Zheng BJ, and Jiang S

Biochemical and biophysical research communications 384(4):486-90, 2009 Jul 10 - Who cited this? | PubMed ID: 19422787 | Fulltext

Chromodomain helicase/adenosine triphosphatase DNA binding protein 1-like (CHD1l) gene suppresses the nucleus-to-mitochondria translocation of nur77 to sustain hepatocellular carcinoma cell survival.

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Chen L, Hu L, Chan TH, Tsao GS, Xie D, Huo KK, Fu L, Ma S, Zheng BJ, and Guan XY

Hepatology (Baltimore, Md.) 50(1):122-9, 2009 Jul - Who cited this? | PubMed ID: 19441106 | Fulltext

Severe Acute Respiratory Syndrome Coronavirus M Protein Inhibits Type I Interferon Production by Impeding the Formation of TRAF3{middle dot}TANK{middle dot}TBK1/IKK{epsilon} Complex.

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Siu KL, Kok KH, Ng MH, Poon VK, Yuen KY, Zheng BJ, and Jin DY

The Journal of biological chemistry 284(24):16202-9, 2009 Jun 12 - Who cited this? | PubMed ID: 19380580 | Fulltext

Antibodies against H5 and H9 avian influenza among poultry workers in China.

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Wang M, Fu CX, and Zheng BJ

The New England journal of medicine 360(24):2583-4, 2009 Jun 11 - Who cited this? | PubMed ID: 19516044 | Fulltext

Severe acute respiratory syndrome coronavirus accessory protein 9b is a virion-associated protein.

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Xu K, Zheng BJ, Zeng R, Lu W, Lin YP, Xue L, Li L, Yang LL, Xu C, Dai J, Wang F, Li Q, Dong QX, Yang RF, Wu JR, and Sun B

Virology 388(2):279-85, 2009 Jun 5 - Who cited this? | PubMed ID: 19394665 | Fulltext

A regulatory polymorphism in interferon-gamma receptor 1 promoter is associated with the susceptibility to chronic hepatitis B virus infection.

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Zhou J, Chen DQ, Poon VK, Zeng Y, Ng F, Lu L, Huang JD, Yuen KY, and Zheng BJ

Immunogenetics 61(6):423-30, 2009 Jun - Who cited this? | PubMed ID: 19488747 | Fulltext

Development of interfering RNA agents to inhibit SARS-associated coronavirus infection and replication.

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He ML, Zheng BJ, Chen Y, Wong KL, Huang JD, Lin MC, Yuen KY, Sung JJ, and Kung HF

Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine 15(3 Suppl 4):28-31, 2009 Jun - Who cited this? | PubMed ID: 19509435 | Fulltext

Examination of seroprevalence of coronavirus HKU1 infection with S protein-based ELISA and neutralization assay against viral spike pseudotyped virus.

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Chan CM, Tse H, Wong SS, Woo PC, Lau SK, Chen L, Zheng BJ, Huang JD, and Yuen KY

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 45(1):54-60, 2009 May - Who cited this? | PubMed ID: 19342289 | Fulltext

The spike protein of SARS-CoV--a target for vaccine and therapeutic development.

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Du L, He Y, Zhou Y, Liu S, Zheng BJ, and Jiang S

Nature reviews. Microbiology 7(3):226-36, 2009 Mar - Who cited this? | PubMed ID: 19198616 | Fulltext

Construction and characterization of a replication-competent human adenovirus type 3-based vector as a live-vaccine candidate and a viral delivery vector.

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Zhang Q, Su X, Seto D, Zheng BJ, Tian X, Sheng H, Li H, Wang Y, and Zhou R

Vaccine 27(8):1145-53, 2009 Feb 18 - Who cited this? | PubMed ID: 19146906 | Fulltext

Roles of spike protein in the pathogenesis of SARS coronavirus.

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Jin DY and Zheng BJ

Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine 15 Suppl 2:37-40, 2009 Feb - Who cited this? | PubMed ID: 19258633 | Fulltext

Inhibition of HBV replication and gene expression in vitro and in vivo with a single AAV vector delivering two shRNA molecules.

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Li Z, He ML, Yao H, Dong QM, Chen YC, Chan CY, Zheng BJ, Yuen KY, Peng Y, Sun Q, Yang X, Lin MC, Sung JJ, and Kung HF

BMB reports 42(1):59-64, 2009 Jan 31 - Who cited this? | PubMed ID: 19192395 | Fulltext

Interaction between SARS-CoV helicase and a multifunctional cellular protein (Ddx5) revealed by yeast and mammalian cell two-hybrid systems.

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Chen JY, Chen WN, Poon KM, Zheng BJ, Lin X, Wang YX, and Wen YM

Archives of virology 154(3):507-12, 2009 - Who cited this? | PubMed ID: 19224332 | Fulltext

Small interfering RNA targeting m2 gene induces effective and long term inhibition of influenza a virus replication.

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Sui HY, Zhao GY, Huang JD, Jin DY, Yuen KY, and Zheng BJ

PLoS ONE 4(5):e5671, 2009 - Who cited this? | PubMed ID: 19479060 | Fulltext

The y271 and i274 amino acids in reverse transcriptase of human immunodeficiency virus-1 are critical to protein stability.

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Zhang HJ, Wang YX, Wu H, Jin DY, Wen YM, and Zheng BJ

PLoS ONE 4(7):e6108, 2009 - Who cited this? | PubMed ID: 19578544 | Fulltext

Transgenic CHD1L expression in mouse induces spontaneous tumors.

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Chen M, Huang JD, Hu L, Zheng BJ, Chen L, Tsang SL, and Guan XY

PLoS ONE 4(8):e6727, 2009 - Who cited this? | PubMed ID: 19701453 | Fulltext

Mutational analysis of the "turn" of helix clamp motif of HIV-1 reverse transcriptase.

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Wang YX, Zhang HJ, Xu J, Zheng BJ, and Wen YM

Biochemical and biophysical research communications 377(3):915-20, 2008 Dec 19 - Who cited this? | PubMed ID: 18976635 | Fulltext

Potential infections of H5N1 and H9N2 avian influenza do exist in Guangdong populations of China.

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Lu CY, Lu JH, Chen WQ, Jiang LF, Tan BY, Ling WH, Zheng BJ, and Sui HY

Chinese medical journal 121(20):2050-3, 2008 Oct 20 - Who cited this? | PubMed ID: 19080274 | Fulltext

Spike protein of human coronavirus HKU1: role in viral life cycle and antibody detection.

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Chan CM, Woo PC, Lau SK, Tse H, Chen HL, Li F, Zheng BJ, Chen L, Huang JD, and Yuen KY

Experimental biology and medicine (Maywood, N.J.), 2008 Oct 10 - Who cited this? | PubMed ID: 18849544 | Fulltext

Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis.

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Lam QL, Ko OK, Zheng BJ, and Lu L

Proceedings of the National Academy of Sciences of the United States of America, 2008 Sep 26 - Who cited this? | PubMed ID: 18820032 | Fulltext

Natural killer cell degeneration exacerbates experimental arthritis in mice via enhanced interleukin-17 production.

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Lo CK, Lam QL, Sun L, Wang S, Ko KH, Xu H, Wu CY, Zheng BJ, and Lu L

Arthritis and rheumatism 58(9):2700, 2008 Sep - Who cited this? | PubMed ID: 18759269 | Fulltext

A non-synonymous single nucleotide polymorphism in IFNAR1 affects susceptibility to chronic hepatitis B virus infection.

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Zhou J, Smith DK, Lu L, Poon VK, Ng F, Chen DQ, Huang JD, Yuen KY, Cao KY, and Zheng BJ

Journal of viral hepatitis, 2008 Aug 28 - Who cited this? | PubMed ID: 18761606 | Fulltext

Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4.

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Lau SK, Woo PC, Tse H, Fu CT, Au WK, Chen XC, Tsoi HW, Tsang TH, Chan JS, Tsang DN, Li KS, Tse CW, Ng TK, Tsang OT, Zheng BJ, Tam S,

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The Journal of general virology 89(Pt 8):1840-8, 2008 Aug - Who cited this? | PubMed ID: 18632954 | Fulltext

Helicases as antiviral drug targets.

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Huang JD, Zheng BJ, and Sun HZ

Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine 14 Suppl 4:36-8, 2008 Aug - Who cited this? | PubMed ID: 18708673 | Fulltext

Studies of SARS virus vaccines.

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Zheng BJ, Du LY, Zhao GY, Lin YP, Sui HY, Chan C, Ma S, Guan Y, and Yuen KY

Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine 14 Suppl 4:39-43, 2008 Aug - Who cited this? | PubMed ID: 18708674 | Fulltext

Aldehyde Dehydrogenase Discriminates the CD133 Liver Cancer Stem Cell Populations.

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Ma S, Chan KW, Lee TK, Tang KH, Wo JY, Zheng BJ, and Guan XY

Molecular cancer research : MCR 6(7):1146, 2008 Jul - Who cited this? | PubMed ID: 18644979 | Fulltext

Delayed antiviral plus immunomodulator treatment still reduces mortality in mice infected by high inoculum of influenza A/H5N1 virus.

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Zheng BJ, Chan KW, Lin YP, Zhao GY, Chan C, Zhang HJ, Chen HL, Wong SS, Lau SK, Woo PC, Chan KH, Jin DY, and Yuen KY

Proceedings of the National Academy of Sciences of the United States of America 105(23):8091, 2008 Jun 10 - Who cited this? | PubMed ID: 18523003 | Fulltext

Inhibition of HBV gene expression and replication by stably expressed interferon-alpha1 via adeno-associated viral vectors.

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Li Z, Yao H, Ma Y, Dong Q, Chen Y, Peng Y, Zheng BJ, Huang JD, Chan CY, Lin MC, Sung JJ, Yuen KY, Kung HF, and He ML

The journal of gene medicine 10(6):619-27, 2008 Jun - Who cited this? | PubMed ID: 18383553 | Fulltext

Priming with rAAV encoding RBD of SARS-CoV S protein and boosting with RBD-specific peptides for T cell epitopes elevated humoral and cellular immune responses against SARS-CoV infection.

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Du L, Zhao G, Lin Y, Chan C, He Y, Jiang S, Wu C, Jin DY, Yuen KY, Zhou Y, and Zheng BJ

Vaccine 26(13):1644, 2008 Mar 20 - Who cited this? | PubMed ID: 18289745 | Fulltext

CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway.

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Ma S, Lee TK, Zheng BJ, Chan KW, and Guan XY

Oncogene 27(12):1749-58, 2008 Mar 13 - Who cited this? | PubMed ID: 17891174 | Fulltext

Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma.

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Ma NF, Hu L, Fung JM, Xie D, Zheng BJ, Chen L, Tang DJ, Fu L, Wu Z, Chen M, Fang Y, and Guan XY

Hepatology (Baltimore, Md.) 47(2):503, 2008 Feb - Who cited this? | PubMed ID: 18023026 | Fulltext

Intranasal Vaccination of Recombinant Adeno-Associated Virus Encoding Receptor-Binding Domain of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Spike Protein Induces Strong Mucosal Immune Responses and Provides Long-Term Protection against SARS-CoV Infection.

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Du L, Zhao G, Lin Y, Sui H, Chan C, Ma S, He Y, Jiang S, Wu C, Yuen KY, Jin DY, Zhou Y, and Zheng BJ

Journal of immunology (Baltimore, Md. : 1950) 180(2):948-56, 2008 Jan 15 - Who cited this? | PubMed ID: 18178835 | Fulltext

Development of subunit vaccines against severe acute respiratory syndrome.

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Du L, He Y, Jiang S, and Zheng BJ

Drugs of today (Barcelona, Spain : 1998) 44(1):63-73, 2008 Jan - Who cited this? | PubMed ID: 18301805 | Fulltext

High expression of PSM-E correlated with tumor grade in prostate cancer: A new alternatively spliced variant of prostate-specific membrane antigen.

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Cao KY, Mao XP, Wang DH, Xu L, Yuan GQ, Dai SQ, Zheng BJ, and Qiu SP

The Prostate 67(16):1791-800, 2007 Dec 1 - Who cited this? | PubMed ID: 17929272 | Fulltext

Inhibition of SARS coronavirus helicase by bismuth complexes.

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Yang N, Tanner JA, Wang Z, Huang JD, Zheng BJ, Zhu N, and Sun H

Chemical communications (Cambridge, England)(42):4413-5, 2007 Nov 14 - Who cited this? | PubMed ID: 17957304 | Fulltext

Complete genome sequence of bat coronavirus HKU2 from Chinese horseshoe bats revealed a much smaller spike gene with a different evolutionary lineage from the rest of the genome.

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Lau SK, Woo PC, Li KS, Huang Y, Wang M, Lam CS, Xu H, Guo R, Chan KH, Zheng BJ, and Yuen KY

Virology 367(2):428-39, 2007 Oct 25 - Who cited this? | PubMed ID: 17617433 | Fulltext

Leptin induces CD40 expression through the activation of Akt in murine dendritic cells.

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Lam QL, Zheng BJ, Jin DY, Cao X, and Lu L

The Journal of biological chemistry 282(38):27587, 2007 Sep 21 - Who cited this? | PubMed ID: 17660512 | Fulltext

Cleavage of spike protein of SARS coronavirus by protease factor Xa is associated with viral infectivity.

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Du L, Kao RY, Zhou Y, He Y, Zhao G, Wong C, Jiang S, Yuen KY, Jin DY, and Zheng BJ

Biochemical and biophysical research communications 359(1):174-9, 2007 Jul 20 - Who cited this? | PubMed ID: 17533109 | Fulltext

Evaluation of an in-house genotyping resistance test for HIV-1 drug resistance interpretation and genotyping.

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Chen JH, Wong KH, Chan K, Lam HY, Lee SS, Li P, Lee MP, Tsang DN, Zheng BJ, Yuen KY, and Yam WC

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 39(2):125-31, 2007 Jun - Who cited this? | PubMed ID: 17449318 | Fulltext

Identification and characterization of tumorigenic liver cancer stem/progenitor cells.

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Ma S, Chan KW, Hu L, Lee TK, Wo JY, Ng IO, Zheng BJ, and Guan XY

Gastroenterology 132(7):2542-56, 2007 Jun - Who cited this? | PubMed ID: 17570225 | Fulltext

Receptor-binding domain of SARS-CoV spike protein induces long-term protective immunity in an animal model.

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Du L, Zhao G, He Y, Guo Y, Zheng BJ, Jiang S, and Zhou Y

Vaccine 25(15):2832-8, 2007 Apr 12 - Who cited this? | PubMed ID: 17092615 | Fulltext

Difference in T helper responses during hepatitis flares in hepatitis B e antigen (HBeAg)-positive patients with genotypes B and C: implication for early HBeAg seroconversion.

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Yuen MF, Wong DK, Zheng BJ, Chan CC, Yuen JC, Wong BC, and Lai CL

Journal of viral hepatitis 14(4):269-75, 2007 Apr - Who cited this? | PubMed ID: 17381719 | Fulltext

Impaired V(D)J recombination and increased apoptosis among B cell precursors in the bone marrow of c-Abl-deficient mice.

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Lam QL, Lo CK, Zheng BJ, Ko KH, Osmond DG, Wu GE, Rottapel R, and Lu L

International immunology 19(3):267-76, 2007 Mar - Who cited this? | PubMed ID: 17229817 | Fulltext

Polymorphisms of type I interferon receptor 1 promoter and their effects on chronic hepatitis B virus infection.

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Zhou J, Lu L, Yuen MF, Lam TW, Chung CP, Lam CL, Zhang B, Wang S, Chen Y, Wu SH, Poon VK, Ng F, Chan CC, Jiang S, Yuen KY, and Zheng BJ

Journal of hepatology 46(2):198-205, 2007 Feb - Who cited this? | PubMed ID: 17125879 | Fulltext

Comparative analysis of twelve genomes of three novel group 2c and group 2d coronaviruses reveals unique group and subgroup features.

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Woo PC, Wang M, Lau SK, Xu H, Poon RW, Guo R, Wong BH, Gao K, Tsoi HW, Huang Y, Li KS, Lam CS, Chan KH, Zheng BJ, and Yuen KY

Journal of virology 81(4):1574-85, 2007 Feb - Who cited this? | PubMed ID: 17121802 | Fulltext

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