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Papers authored by Wiviott SD

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Use of Evidence-Based Therapies in Short-Term Outcomes of ST-Segment Elevation Myocardial Infarction and Non-ST-Segment Elevation Myocardial Infarction in Patients With Chronic Kidney Disease: A Report From the National Cardiovascular Data Acute Coronary Treatment and Intervention Outcomes Network Registry.

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Fox CS, Muntner P, Chen AY, Alexander KP, Roe MT, Cannon CP, Saucedo JF, Kontos MC, and Wiviott SD

Circulation 121(3):357-65, 2010 Jan 26 - Who cited this? | PubMed ID: 20065168 | Fulltext

Combination therapy with clopidogrel and proton-pump inhibitors - Authors' reply.

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O'Donoghue ML, Braunwald E, Antman EM, Murphy SA, and Wiviott SD

Lancet 375(9708):28-9, 2010 Jan 2 - Who cited this? | PubMed ID: 20109857 | Fulltext

Extent of ST-segment resolution after fibrinolysis adds improved risk stratification to clinical risk score for ST-segment elevation myocardial infarction.

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Harkness JR, Sabatine MS, Braunwald E, Morrow DA, Sloan S, Wiviott SD, Giugliano RP, Antman EM, Cannon CP, and Scirica BM

American heart journal 159(1):55-62, 2010 Jan - Who cited this? | PubMed ID: 20102867 | Fulltext

Reduction in Recurrent Cardiovascular Events With Intensive Lipid-Lowering Statin Therapy Compared With Moderate Lipid-Lowering Statin Therapy After Acute Coronary Syndromes From the PROVE IT-TIMI 22 (Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22) Trial.

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Murphy SA, Cannon CP, Wiviott SD, McCabe CH, and Braunwald E

Journal of the American College of Cardiology 54(25):2358-62, 2009 Dec 15 - Who cited this? | PubMed ID: 20082923 | Fulltext

Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials.

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O'Donoghue ML, Braunwald E, Antman EM, Murphy SA, Bates ER, Rozenman Y, Michelson AD, Hautvast RW, Ver Lee PN, Close SL, Shen L, Mega JL, Sabatine MS, and Wiviott SD

Lancet 374(9694):989-97, 2009 Sep 19 - Who cited this? | PubMed ID: 19726078 | Fulltext

Effect of prasugrel versus clopidogrel on outcomes among patients with acute coronary syndrome undergoing percutaneous coronary intervention without stent implantation: a TRial to assess Improvement in Therapeutic Outcomes by optimizing platelet inhibitioN with prasugrel (TRITON)-Thrombolysis in Myocardial Infarction (TIMI) 38 substudy.

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Pride YB, Wiviott SD, Buros JL, Zorkun C, Tariq MU, Antman EM, Braunwald E, Gibson CM, and TIMI Study Group

American heart journal 158(3):e21-6, 2009 Sep - Who cited this? | PubMed ID: 19699846 | Fulltext

The efficacy and safety of prasugrel with and without a glycoprotein IIb/IIIa inhibitor in patients with acute coronary syndromes undergoing percutaneous intervention: a TRITON-TIMI 38 (Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel-Thrombolysis In Myocardial Infarction 38) Analysis.

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O'Donoghue M, Antman EM, Braunwald E, Murphy SA, Steg PG, Finkelstein A, Penny WF, Fridrich V, McCabe CH, Sabatine MS, and Wiviott SD

Journal of the American College of Cardiology 54(8):678-85, 2009 Aug 18 - Who cited this? | PubMed ID: 19679245 | Fulltext

Population Pharmacokinetic Analyses to Evaluate the Influence of Intrinsic and Extrinsic Factors on Exposure of Prasugrel Active Metabolite in TRITON-TIMI 38.

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Wrishko RE, Ernest CS, Small DS, Li YG, Weerakkody GJ, Riesmeyer JR, Macias WL, Rohatagi S, Salazar DE, Antman EM, Wiviott SD, Braunwald E, and Ni L

Journal of clinical pharmacology 49(8):984-98, 2009 Aug - Who cited this? | PubMed ID: 19546250 | Fulltext

Safety and efficacy of achieving very low low-density lipoprotein cholesterol levels with rosuvastatin 40 mg daily (from the ASTEROID Study).

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Wiviott SD, Mohanavelu S, Raichlen JS, Cain VA, Nissen SE, and Libby P

The American journal of cardiology 104(1):29-35, 2009 Jul 1 - Who cited this? | PubMed ID: 19576317 | Fulltext

Pharmacodynamic assessment of platelet inhibition by prasugrel vs. clopidogrel in the TRITON-TIMI 38 trial.

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Michelson AD, Frelinger AL, Braunwald E, Downey WE, Angiolillo DJ, Xenopoulos NP, Jakubowski JA, Li Y, Murphy SA, Qin J, McCabe CH, Antman EM, Wiviott SD, and TRITON-TIMI 38 Investigators

European heart journal 30(14):1753-63, 2009 Jul - Who cited this? | PubMed ID: 19435740 | Fulltext

Effect of the novel thienopyridine prasugrel compared with clopidogrel on spontaneous and procedural myocardial infarction in the trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with prasugrel-thrombolysis in myocardial infarction 38: an application of the classification system from the universal definition of myocardial infarction.

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Morrow DA, Wiviott SD, White HD, Nicolau JC, Bramucci E, Murphy SA, Bonaca MP, Ruff CT, Scirica BM, McCabe CH, Antman EM, and Braunwald E

Circulation 119(21):2758-64, 2009 Jun 2 - Who cited this? | PubMed ID: 19451347 | Fulltext

Cytochrome p450 genetic polymorphisms and the response to prasugrel: relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes.

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Mega JL, Close SL, Wiviott SD, Shen L, Hockett RD, Brandt JT, Walker JR, Antman EM, Macias WL, Braunwald E, and Sabatine MS

Circulation 119(19):2553-60, 2009 May 19 - Who cited this? | PubMed ID: 19414633 | Fulltext

Seasonal variation in lipids in patients following acute coronary syndrome on fixed doses of Pravastatin (40 mg) or Atorvastatin (80 mg) (from the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22 [PROVE IT-TIMI 22] Study).

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Tung P, Wiviott SD, Cannon CP, Murphy SA, McCabe CH, and Gibson CM

The American journal of cardiology 103(8):1056-60, 2009 Apr 15 - Who cited this? | PubMed ID: 19361589 | Fulltext

Thrombolysis in Myocardial Infarction (TIMI) Risk Index predicts long-term mortality and heart failure in patients with ST-elevation myocardial infarction in the TIMI 2 clinical trial.

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Truong QA, Cannon CP, Zakai NA, Rogers IS, Giugliano RP, Wiviott SD, McCabe CH, Morrow DA, and Braunwald E

American heart journal 157(4):673-679.e1, 2009 Apr - Who cited this? | PubMed ID: 19332194 | Fulltext

Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): double-blind, randomised controlled trial.

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Montalescot G, Wiviott SD, Braunwald E, Murphy SA, Gibson CM, McCabe CH, Antman EM, and TRITON-TIMI 38 investigators

Lancet 373(9665):723-31, 2009 Feb 28 - Who cited this? | PubMed ID: 19249633 | Fulltext

Cytochrome p-450 polymorphisms and response to clopidogrel.

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Mega JL, Close SL, Wiviott SD, Shen L, Hockett RD, Brandt JT, Walker JR, Antman EM, Macias W, Braunwald E, and Sabatine MS

The New England journal of medicine 360(4):354-62, 2009 Jan 22 - Who cited this? | PubMed ID: 19106084 | Fulltext

Utilization and impact of pre-hospital electrocardiograms for patients with acute ST-segment elevation myocardial infarction: data from the NCDR (National Cardiovascular Data Registry) ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry.

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Diercks DB, Kontos MC, Chen AY, Pollack CV, Wiviott SD, Rumsfeld JS, Magid DJ, Gibler WB, Cannon CP, Peterson ED, and Roe MT

Journal of the American College of Cardiology 53(2):161-6, 2009 Jan 13 - Who cited this? | PubMed ID: 19130984 | Fulltext

Streptokinase and Enoxaparin as an Alternative to Fibrin-Specific Lytic-Based Regimens: An ExTRACT-TIMI 25 Analysis.

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Giraldez RR, Wiviott SD, Nicolau JC, Mohanavelu S, Morrow DA, Antman EM, and Giugliano RP

Drugs 69(11):1433-43, 2009 - Who cited this? | PubMed ID: 19634922 | Fulltext

Intensity of antiplatelet therapy in patients with acute coronary syndromes and percutaneous coronary intervention: the promise of prasugrel?.

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Wiviott SD

Cardiology clinics 26(4):629-37, 2008 Nov - Who cited this? | PubMed ID: 18929236 | Fulltext

Greater clinical benefit of more intensive oral antiplatelet therapy with prasugrel in patients with diabetes mellitus in the trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with prasugrel-Thrombolysis in Myocardial Infarction 38.

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Wiviott SD, Braunwald E, Angiolillo DJ, Meisel S, Dalby AJ, Verheugt FW, Goodman SG, Corbalan R, Purdy DA, Murphy SA, McCabe CH, Antman EM, and TRITON-TIMI 38 Investigators

Circulation 118(16):1626-36, 2008 Oct 14 - Who cited this? | PubMed ID: 18757948 | Fulltext

Reduction in recurrent cardiovascular events with prasugrel compared with clopidogrel in patients with acute coronary syndromes from the TRITON-TIMI 38 trial.

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Murphy SA, Antman EM, Wiviott SD, Weerakkody G, Morocutti G, Huber K, Lopez-Sendon J, McCabe CH, Braunwald E, and TRITON-TIMI 38 Investigators

European heart journal 29(20):2473-9, 2008 Oct - Who cited this? | PubMed ID: 18682445 | Fulltext

Lack of association between soluble CD40L and risk in a large cohort of patients with acute coronary syndrome in OPUS TIMI-16.

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Olenchock BA, Wiviott SD, Murphy SA, Cannon CP, Rifai N, Braunwald E, and Morrow DA

Journal of thrombosis and thrombolysis 26(2):79-84, 2008 Oct - Who cited this? | PubMed ID: 17917707 | Fulltext

Outcomes of Patients With Acute Coronary Syndrome and Previous Coronary Artery Bypass Grafting (from the Pravastatin or Atorvastatin Evaluation and Infection Therapy [PROVE IT-TIMI 22] and the Aggrastat to Zocor [A to Z] Trials).

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Brilakis ES, de Lemos JA, Cannon CP, Wiviott SD, Murphy SA, Morrow DA, Sabatine MS, Banerjee S, Blazing MA, Califf RM, and Braunwald E

The American journal of cardiology 102(5):552-8, 2008 Sep 1 - Who cited this? | PubMed ID: 18721511 | Fulltext

Early and Late Benefits of Prasugrel in Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention A TRITON-TIMI 38 (TRial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet InhibitioN with Prasugrel-Thrombolysis In Myocardial Infarction) Analysis.

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Antman EM, Wiviott SD, Murphy SA, Voitk J, Hasin Y, Widimsky P, Chandna H, Macias W, McCabe CH, and Braunwald E

Journal of the American College of Cardiology 51(21):2028-33, 2008 May 27 - Who cited this? | PubMed ID: 18498956 | Fulltext

A perspective on the efficacy and safety of intensive antiplatelet therapy in the trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with prasugrel-thrombolysis in myocardial infarction 38.

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Wiviott SD, Braunwald E, Murphy SA, Antman EM, and TRITON-TIMI 38 Investigators

The American journal of cardiology 101(9):1367-70, 2008 May 1 - Who cited this? | PubMed ID: 18435974 | Fulltext

Intensive oral antiplatelet therapy for reduction of ischaemic events including stent thrombosis in patients with acute coronary syndromes treated with percutaneous coronary intervention and stenting in the TRITON-TIMI 38 trial: a subanalysis of a randomised trial.

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Wiviott SD, Braunwald E, McCabe CH, Horvath I, Keltai M, Herrman JP, Van de Werf F, Downey WE, Scirica BM, Murphy SA, Antman EM, and TRITON-TIMI 38 Investigators

Lancet 371(9621):1353-63, 2008 Apr 19 - Who cited this? | PubMed ID: 18377975 | Fulltext

Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial.

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Wiviott SD, Trenk D, Frelinger AL, O'Donoghue M, Neumann FJ, Michelson AD, Angiolillo DJ, Hod H, Montalescot G, Miller DL, Jakubowski JA, Cairns R, Murphy SA, McCabe CH, Antman EM, Braunwald E,

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Circulation 116(25):2923-32, 2007 Dec 18 - Who cited this? | PubMed ID: 18056526 | Fulltext

Effect of thrombocytopenia on outcomes following treatment with either enoxaparin or unfractionated heparin in patients presenting with acute coronary syndromes.

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Yeh RW, Wiviott SD, Giugliano RP, Morrow DA, Shui A, Qin J, Scirica B, Bradner JE, Jang IK, Gibson CM, and Antman EM

The American journal of cardiology 100(12):1734, 2007 Dec 15 - Who cited this? | PubMed ID: 18082517 | Fulltext

Serial measurement of monocyte chemoattractant protein-1 after acute coronary syndromes: results from the A to Z trial.

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de Lemos JA, Morrow DA, Blazing MA, Jarolim P, Wiviott SD, Sabatine MS, Califf RM, and Braunwald E

Journal of the American College of Cardiology 50(22):2117-24, 2007 Nov 27 - Who cited this? | PubMed ID: 18036447 | Fulltext

Prasugrel versus clopidogrel in patients with acute coronary syndromes.

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Wiviott SD, Braunwald E, McCabe CH, Montalescot G, Ruzyllo W, Gottlieb S, Neumann FJ, Ardissino D, De Servi S, Murphy SA, Riesmeyer J, Weerakkody G, Gibson CM, Antman EM, and

The New England journal of medicine 357(20):2001, 2007 Nov 15 - Who cited this? | PubMed ID: 17982182 | Fulltext

TIMI risk index and the benefit of enoxaparin in patients with ST-elevation myocardial infarction.

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Ruff CT, Wiviott SD, Morrow DA, Mohanavelu S, Murphy SA, Antman EM, Braunwald E, and ExTRACT-TIMI 25 Investigators

The American journal of medicine 120(11):993-8, 2007 Nov - Who cited this? | PubMed ID: 17976428 | Fulltext

Effect of intensive lipid-lowering therapy on mortality after acute coronary syndrome (a patient-level analysis of the Aggrastat to Zocor and Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 trials).

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Murphy SA, Cannon CP, Wiviott SD, de Lemos JA, Blazing MA, McCabe CH, Califf RM, and Braunwald E

The American journal of cardiology 100(7):1047-51, 2007 Oct 1 - Who cited this? | PubMed ID: 17884359 | Fulltext

Clinical application of C-reactive protein across the spectrum of acute coronary syndromes.

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Scirica BM, Morrow DA, Cannon CP, de Lemos JA, Murphy S, Sabatine MS, Wiviott SD, Rifai N, McCabe CH, Braunwald E, and Thrombolysis in Myocardial Infarction (TIMI) Study Group

Clinical chemistry 53(10):1800-7, 2007 Oct - Who cited this? | PubMed ID: 17717132 | Fulltext

Antiplatelet agents make a comeback in ST-elevation myocardial infarction.

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Wiviott SD and de Lemos JA

American heart journal 154(4):603-6, 2007 Oct - Who cited this? | PubMed ID: 17892976 | Fulltext

A strategy of using enoxaparin as adjunctive antithrombin therapy reduces death and recurrent myocardial infarction in patients who achieve early ST-segment resolution after fibrinolytic therapy: the ExTRACT-TIMI 25 ECG study.

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Scirica BM, Morrow DA, Sadowski Z, Ruda M, Nicolau JC, Giugliano RP, Wiviott SD, Sabatine MS, Shui A, Antman EM, and Braunwald E

European heart journal 28(17):2070-6, 2007 Sep - Who cited this? | PubMed ID: 17600039 | Fulltext

New antiplatelet therapies for acute coronary syndromes.

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Rich JD and Wiviott SD

Current cardiology reports 9(4):303-11, 2007 Jul - Who cited this? | PubMed ID: 17601397 | Fulltext

Recombinant nematode anticoagulant protein c2 in patients with non-ST-segment elevation acute coronary syndrome: the ANTHEM-TIMI-32 trial.

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Giugliano RP, Wiviott SD, Stone PH, Simon DI, Schweiger MJ, Bouchard A, Leesar MA, Goulder MA, Deitcher SR, McCabe CH, Braunwald E, and ANTHEM-TIMI-32 Investigators

Journal of the American College of Cardiology 49(25):2398-407, 2007 Jun 26 - Who cited this? | PubMed ID: 17599602 | Fulltext

Hemodynamic significance of periprocedural myocardial injury assessed with N-terminal pro-B-type natriuretic peptide after percutaneous coronary intervention in patients with stable and unstable coronary artery disease (from the JUMBO-TIMI 26 trial).

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Bonaca MP, Wiviott SD, Sabatine MS, Buros J, Murphy SA, Scirica BM, Rifai N, Antman EM, and Morrow DA

The American journal of cardiology 99(3):344-8, 2007 Feb 1 - Who cited this? | PubMed ID: 17261395 | Fulltext

A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation.

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Brandt JT, Payne CD, Wiviott SD, Weerakkody G, Farid NA, Small DS, Jakubowski JA, Naganuma H, and Winters KJ

American heart journal 153(1):66.e9-16, 2007 Jan - Who cited this? | PubMed ID: 17174640 | Fulltext

The safety and efficacy of achieving very low LDL-cholesterol concentrations with high dose statin therapy.

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Wiviott SD and Cannon CP

Current opinion in lipidology 17(6):626-30, 2006 Dec - Who cited this? | PubMed ID: 17095906 | Fulltext

Clopidogrel response variability and future therapies: clopidogrel: does one size fit all?.

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O'Donoghue M and Wiviott SD

Circulation 114(22):e600-6, 2006 Nov 28 - Who cited this? | PubMed ID: 17130347 | Fulltext

Clopidogrel response variability, resistance, or both?.

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Wiviott SD

The American journal of cardiology 98(10A):18N-24N, 2006 Nov 20 - Who cited this? | PubMed ID: 17097413 | Fulltext

Benefits of achieving the NCEP optional LDL-C goal among elderly patients with ACS.

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Ray KK, Bach RG, Cannon CP, Cairns R, Kirtane AJ, Wiviott SD, McCabe CH, Braunwald E, Gibson CM, and PROVE IT-TIMI 22 Investigators

European heart journal 27(19):2310-6, 2006 Oct - Who cited this? | PubMed ID: 16887854 | Fulltext

Evaluation of prasugrel compared with clopidogrel in patients with acute coronary syndromes: design and rationale for the TRial to assess Improvement in Therapeutic Outcomes by optimizing platelet InhibitioN with prasugrel Thrombolysis In Myocardial Infarction 38 (TRITON-TIMI 38).

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Wiviott SD, Antman EM, Gibson CM, Montalescot G, Riesmeyer J, Weerakkody G, Winters KJ, Warmke JW, McCabe CH, Braunwald E, and TRITON-TIMI 38 Investigators

American heart journal 152(4):627-35, 2006 Oct - Who cited this? | PubMed ID: 16996826 | Fulltext

Evaluation of the National Cholesterol Education Program Adult Treatment Panel III algorithm for selecting candidates for statin therapy: insights from the A to Z trial.

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de Lemos JA, Wiviott SD, Murphy SA, Blazing MA, Lewis EF, Califf RM, Pfeffer MA, and Braunwald E

The American journal of cardiology 98(6):739-42, 2006 Sep 15 - Who cited this? | PubMed ID: 16950174 | Fulltext

Update on lipid-lowering therapy and LDL-cholesterol targets.

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Wiviott SD and Cannon CP

Nature clinical practice. Cardiovascular medicine 3(8):424-36, 2006 Aug - Who cited this? | PubMed ID: 16874355 | Fulltext

Clinical relevance of C-reactive protein during follow-up of patients with acute coronary syndromes in the Aggrastat-to-Zocor Trial.

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Morrow DA, de Lemos JA, Sabatine MS, Wiviott SD, Blazing MA, Shui A, Rifai N, Califf RM, and Braunwald E

Circulation 114(4):281, 2006 Jul 25 - Who cited this? | PubMed ID: 16847150 | Fulltext

The role of clopidogrel in early and sustained arterial patency after fibrinolysis for ST-segment elevation myocardial infarction: the ECG CLARITY-TIMI 28 Study.

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Scirica BM, Sabatine MS, Morrow DA, Gibson CM, Murphy SA, Wiviott SD, Giugliano RP, McCabe CH, Cannon CP, and Braunwald E

Journal of the American College of Cardiology 48(1):37-42, 2006 Jul 4 - Who cited this? | PubMed ID: 16814646 | Fulltext

Application of the Thrombolysis in Myocardial Infarction risk index in non-ST-segment elevation myocardial infarction: evaluation of patients in the National Registry of Myocardial Infarction.

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Wiviott SD, Morrow DA, Frederick PD, Antman EM, Braunwald E, and National Registry of Myocardial Infarction

Journal of the American College of Cardiology 47(8):1553-8, 2006 Apr 18 - Who cited this? | PubMed ID: 16630990 | Fulltext

A tale of two trials: a comparison of the post-acute coronary syndrome lipid-lowering trials A to Z and PROVE IT-TIMI 22.

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Wiviott SD, de Lemos JA, Cannon CP, Blazing M, Murphy SA, McCabe CH, Califf R, and Braunwald E

Circulation 113(11):1406, 2006 Mar 21 - Who cited this? | PubMed ID: 16534008 | Fulltext

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