Papers authored by Widlund HR

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GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer.
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Scott KL, Kabbarah O, Liang MC, Ivanova E, Anagnostou V, Wu J, Dhakal S, Wu M, Chen S, Feinberg T, Huang J, Saci A, Widlund HR, Fisher DE, Xiao Y, Rimm DL, 
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Nature 459(7250):1085-90, 2009 Jun 25 - Who cited this? | PubMed ID: 19553991 | Fulltext
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Imatinib Targeting of KIT-Mutant Oncoprotein in Melanoma.
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Jiang X, Zhou J, Yuen NK, Corless CL, Heinrich MC, Fletcher JA, Demetri GD, Widlund HR, Fisher DE, and Hodi FS
Clinical cancer research : an official journal of the American Association for Cancer Research 14(23):7726-32, 2008 Dec 1 - Who cited this? | PubMed ID: 19047099 | Fulltext
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Pharmacologic suppression of MITF expression via HDAC inhibitors in the melanocyte lineage.
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Yokoyama S, Feige E, Poling LL, Levy C, Widlund HR, Khaled M, Kung AL, and Fisher DE
Pigment cell & melanoma research, 2008 Jun 27 - Who cited this? | PubMed ID: 18627530 | Fulltext
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Potent p53-independent tumor suppressor activity of ARF in melanoma-genesis.
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Widlund HR and Fisher DE
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 20(5):339-40, 2007 Oct - Who cited this? | PubMed ID: 17850505 | Fulltext
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Central role of p53 in the suntan response and pathologic hyperpigmentation.
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Cui R, Widlund HR, Feige E, Lin JY, Wilensky DL, Igras VE, D'Orazio J, Fung CY, Schanbacher CF, Granter SR, and Fisher DE
Cell 128(5):853, 2007 Mar 9 - Who cited this? | PubMed ID: 17350573 | Fulltext
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Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers.
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Davis IJ, Kim JJ, Ozsolak F, Widlund HR, Rozenblatt-Rosen O, Granter SR, Du J, Fletcher JA, Denny CT, Lessnick SL, Linehan WM, Kung AL, and Fisher DE
Cancer cell 9(6):473-84, 2006 Jun - Who cited this? | PubMed ID: 16766266 | Fulltext
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Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube.
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Sun T, Hafler BP, Kaing S, Kitada M, Ligon KL, Widlund HR, Yuk DI, Stiles CD, and Rowitch DH
Developmental biology 292(1):152, 2006 Apr 1 - Who cited this? | PubMed ID: 16469306 | Fulltext
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Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma.
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Garraway LA, Widlund HR, Rubin MA, Getz G, Berger AJ, Ramaswamy S, Beroukhim R, Milner DA, Granter SR, Du J, Lee C, Wagner SN, Li C, Golub TR, Rimm DL, Meyerson ML, 
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Nature 436(7047):117, 2005 Jul 7 - Who cited this? | PubMed ID: 16001072 | Fulltext
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BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma.
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Patton EE, Widlund HR, Kutok JL, Kopani KR, Amatruda JF, Murphey RD, Berghmans S, Mayhall EA, Traver D, Fletcher CD, Aster JC, Granter SR, Look AT, Lee C, Fisher DE, and Zon LI
Current biology : CB 15(3):249, 2005 Feb 8 - Who cited this? | PubMed ID: 15694309 | Fulltext
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Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF.
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Du J, Widlund HR, Horstmann MA, Ramaswamy S, Ross K, Huber WE, Nishimura EK, Golub TR, and Fisher DE
Cancer cell 6(6):565-76, 2004 Dec - Who cited this? | PubMed ID: 15607961 | Fulltext
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Transcriptional regulation of the melanoma prognostic marker melastatin (TRPM1) by MITF in melanocytes and melanoma.
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Miller AJ, Du J, Rowan S, Hershey CL, Widlund HR, and Fisher DE
Cancer research 64(2):509-16, 2004 Jan 15 - Who cited this? | PubMed ID: 14744763 | Fulltext
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Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors.
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Kenney AM, Widlund HR, and Rowitch DH
Development (Cambridge, England) 131(1):217-28, 2004 Jan - Who cited this? | PubMed ID: 14660435 | Fulltext
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A tissue-restricted cAMP transcriptional response: SOX10 modulates alpha-melanocyte-stimulating hormone-triggered expression of microphthalmia-associated transcription factor in melanocytes.
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Huber WE, Price ER, Widlund HR, Du J, Davis IJ, Wegner M, and Fisher DE
The Journal of biological chemistry 278(46):45224, 2003 Nov 14 - Who cited this? | PubMed ID: 12944398 | Fulltext
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MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanoma.
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Du J, Miller AJ, Widlund HR, Horstmann MA, Ramaswamy S, and Fisher DE
The American journal of pathology 163(1):333-43, 2003 Jul - Who cited this? | PubMed ID: 12819038 | Fulltext
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Microphthalamia-associated transcription factor: a critical regulator of pigment cell development and survival.
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Widlund HR and Fisher DE
Oncogene 22(20):3035-41, 2003 May 19 - Who cited this? | PubMed ID: 12789278 | Fulltext
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NFATc2-mediated repression of cyclin-dependent kinase 4 expression.
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Baksh S, Widlund HR, Frazer-Abel AA, Du J, Fosmire S, Fisher DE, DeCaprio JA, Modiano JF, and Burakoff SJ
Molecular cell 10(5):1071-81, 2002 Nov - Who cited this? | PubMed ID: 12453415 | Fulltext
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Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor.
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Widlund HR, Horstmann MA, Price ER, Cui J, Lessnick SL, Wu M, He X, and Fisher DE
The Journal of cell biology 158(6):1079-87, 2002 Sep 16 - Who cited this? | PubMed ID: 12235125 | Fulltext
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Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability.
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McGill GG, Horstmann M, Widlund HR, Du J, Motyckova G, Nishimura EK, Lin YL, Ramaswamy S, Avery W, Ding HF, Jordan SA, Jackson IJ, Korsmeyer SJ, Golub TR, and Fisher DE
Cell 109(6):707-18, 2002 Jun 14 - Who cited this? | PubMed ID: 12086670 | Fulltext
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DNA sequence-dependent contributions of core histone tails to nucleosome stability: differential effects of acetylation and proteolytic tail removal.
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Widlund HR, Vitolo JM, Thiriet C, and Hayes JJ
Biochemistry 39(13):3835-41, 2000 Apr 4 - Who cited this? | PubMed ID: 10736184 | Fulltext
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Nucleosome structural features and intrinsic properties of the TATAAACGCC repeat sequence.
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Widlund HR, Kuduvalli PN, Bengtsson M, Cao H, Tullius TD, and Kubista M
The Journal of biological chemistry 274(45):31847-52, 1999 Nov 5 - Who cited this? | PubMed ID: 10542209 | Fulltext
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Sequence motifs and free energies of selected natural and non-natural nucleosome positioning DNA sequences.
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Thåström A, Lowary PT, Widlund HR, Cao H, Kubista M, and Widom J
Journal of molecular biology 288(2):213-29, 1999 Apr 30 - Who cited this? | PubMed ID: 10329138 | Fulltext
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TGGA repeats impair nucleosome formation.
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Cao H, Widlund HR, Simonsson T, and Kubista M
Journal of molecular biology 281(2):253-60, 1998 Aug 14 - Who cited this? | PubMed ID: 9698546 | Fulltext
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Identification and characterization of genomic nucleosome-positioning sequences.
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Widlund HR, Cao H, Simonsson S, Magnusson E, Simonsson T, Nielsen PE, Kahn JD, Crothers DM, and Kubista M
Journal of molecular biology 267(4):807-17, 1997 Apr 11 - Who cited this? | PubMed ID: 9135113 | Fulltext
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