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Papers authored by Wewer UM

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alpha9beta1 Integrin in melanoma cells can signal different adhesion states for migration and anchorage.

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Lydolph MC, Morgan-Fisher M, Høye AM, Couchman JR, Wewer UM, and Yoneda A

Experimental cell research 315(19):3312-24, 2009 Nov 15 - Who cited this? | PubMed ID: 19796635 | Fulltext

Impaired cutaneous wound healing in mice lacking tetranectin.

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Iba K, Hatakeyama N, Kojima T, Murata M, Matsumura T, Wewer UM, Wada T, Sawada N, and Yamashita T

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 17(1):108-12, 2009 - Who cited this? | PubMed ID: 19152657 | Fulltext

Targeting ADAM12 in Human Disease: Head, Body or Tail?.

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Jacobsen J and Wewer UM

Current pharmaceutical design 15(20):2300-10, 2009 - Who cited this? | PubMed ID: 19601832 | Fulltext

Heparan sulfate regulates ADAM12 through a molecular switch mechanism.

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Sørensen HP, Vives RR, Manetopoulos C, Albrechtsen R, Lydolph MC, Jacobsen J, Couchman JR, and Wewer UM

The Journal of biological chemistry, 2008 Sep 17 - Who cited this? | PubMed ID: 18801731 | Fulltext

Expression, purification and insights into structure and folding of the ADAM22 pro domain.

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Sørensen HP, Jacobsen J, Nielbo S, Poulsen FM, and Wewer UM

Protein expression and purification, 2008 Jun 13 - Who cited this? | PubMed ID: 18593599 | Fulltext

Catalytic properties of ADAM12 and its domain deletion mutants.

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Jacobsen J, Visse R, Sørensen HP, Enghild JJ, Brew K, Wewer UM, and Nagase H

Biochemistry 47(2):537-47, 2008 Jan 15 - Who cited this? | PubMed ID: 18081311 | Fulltext

Cellular roles of ADAM12 in health and disease.

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Kveiborg M, Albrechtsen R, Couchman JR, and Wewer UM

The international journal of biochemistry & cell biology 40(9):1685-702, 2008 - Who cited this? | PubMed ID: 18342566 | Fulltext

Transgenic overexpression of ADAM12 suppresses muscle regeneration and aggravates dystrophy in aged mdx mice.

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Jørgensen LH, Jensen CH, Wewer UM, and Schrøder HD

The American journal of pathology 171(5):1599, 2007 Nov - Who cited this? | PubMed ID: 17982130 | Fulltext

The disintegrin and metalloproteinase ADAM12 contributes to TGF-beta signaling through interaction with the type II receptor.

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Atfi A, Dumont E, Colland F, Bonnier D, L'helgoualc'h A, Prunier C, Ferrand N, Clément B, Wewer UM, and Théret N

The Journal of cell biology 178(2):201, 2007 Jul 16 - Who cited this? | PubMed ID: 17620406 | Fulltext

ADAM 12 as a second-trimester maternal serum marker in screening for Down syndrome.

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Christiansen M, Spencer K, Laigaard J, Cowans NJ, Larsen SO, and Wewer UM

Prenatal diagnosis 27(7):611-5, 2007 Jul - Who cited this? | PubMed ID: 17465398 | Fulltext

Molecular profiling of ADAM12 in human bladder cancer.

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Fröhlich C, Albrechtsen R, Dyrskjøt L, Rudkjaer L, Ørntoft TF, and Wewer UM

Clinical cancer research : an official journal of the American Association for Cancer Research 12(24):7359, 2006 Dec 15 - Who cited this? | PubMed ID: 17189408 | Fulltext

ADAM 12 as a first-trimester maternal serum marker in screening for Down syndrome.

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Laigaard J, Spencer K, Christiansen M, Cowans NJ, Larsen SO, Pedersen BN, and Wewer UM

Prenatal diagnosis 26(10):973-9, 2006 Oct - Who cited this? | PubMed ID: 16892462 | Fulltext

ADAM12-S stimulates bone growth in transgenic mice by modulating chondrocyte proliferation and maturation.

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Kveiborg M, Albrechtsen R, Rudkjaer L, Wen G, Damgaard-Pedersen K, and Wewer UM

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 21(8):1288-96, 2006 Aug - Who cited this? | PubMed ID: 16869727 | Fulltext

Maternal serum ADAM12 levels in Down and Edwards' syndrome pregnancies at 9-12 weeks' gestation.

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Laigaard J, Cuckle H, Wewer UM, and Christiansen M

Prenatal diagnosis 26(8):689-91, 2006 Aug - Who cited this? | PubMed ID: 16752438 | Fulltext

ADAM12 is a four-leafed clover: the excised prodomain remains bound to the mature enzyme.

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Wewer UM, Mörgelin M, Holck P, Jacobsen J, Lydolph MC, Johnsen AH, Kveiborg M, and Albrechtsen R

The Journal of biological chemistry 281(14):9418-22, 2006 Apr 7 - Who cited this? | PubMed ID: 16455653 | Fulltext

RNA-binding IMPs promote cell adhesion and invadopodia formation.

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Vikesaa J, Hansen TV, Jønson L, Borup R, Wewer UM, Christiansen J, and Nielsen FC

The EMBO journal 25(7):1456-68, 2006 Apr 5 - Who cited this? | PubMed ID: 16541107 | Fulltext

Involvement of the serine/threonine p70S6 kinase in TGF-beta1-induced ADAM12 expression in cultured human hepatic stellate cells.

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Le Pabic H, L'Helgoualc'h A, Coutant A, Wewer UM, Baffet G, Clément B, and Théret N

Journal of hepatology 43(6):1038-44, 2005 Dec - Who cited this? | PubMed ID: 16139919 | Fulltext

ADAM12 overexpression does not improve outcome in mice with laminin alpha2-deficient muscular dystrophy.

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Guo LT, Shelton GD, Wewer UM, and Engvall E

Neuromuscular disorders : NMD 15(11):786-9, 2005 Nov - Who cited this? | PubMed ID: 16198565 | Fulltext

ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins.

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Thodeti CK, Fröhlich C, Nielsen CK, Takada Y, Fässler R, Albrechtsen R, and Wewer UM

FEBS letters 579(25):5589-95, 2005 Oct 24 - Who cited this? | PubMed ID: 16213489 | Fulltext

Hierarchy of ADAM12 binding to integrins in tumor cells.

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Thodeti CK, Fröhlich C, Nielsen CK, Holck P, Sundberg C, Kveiborg M, Mahalingam Y, Albrechtsen R, Couchman JR, and Wewer UM

Experimental cell research 309(2):438-50, 2005 Oct 1 - Who cited this? | PubMed ID: 16061220 | Fulltext

Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer.

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Hammer NA, Hansen TO, Byskov AG, Rajpert-De Meyts E, Grøndahl ML, Bredkjaer HE, Wewer UM, Christiansen J, and Nielsen FC

Reproduction (Cambridge, England) 130(2):203, 2005 Aug - Who cited this? | PubMed ID: 16049158 | Fulltext

A simplified laminin nomenclature.

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Aumailley M, Bruckner-Tuderman L, Carter WG, Deutzmann R, Edgar D, Ekblom P, Engel J, Engvall E, Hohenester E, Jones JC, Kleinman HK, Marinkovich MP, Martin GR, Mayer U, Meneguzzi G, Miner JH,

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Matrix biology : journal of the International Society for Matrix Biology 24(5):326-32, 2005 Aug - Who cited this? | PubMed ID: 15979864 | Fulltext

PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage.

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Li S, Bordoy R, Stanchi F, Moser M, Braun A, Kudlacek O, Wewer UM, Yurchenco PD, and Fässler R

Journal of cell science 118(Pt 13):2913-21, 2005 Jul 1 - Who cited this? | PubMed ID: 15976450 | Fulltext

Reduction of the disintegrin and metalloprotease ADAM12 in preeclampsia.

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Laigaard J, Sørensen T, Placing S, Holck P, Fröhlich C, Wøjdemann KR, Sundberg K, Shalmi AC, Tabor A, Nørgaard-Pedersen B, Ottesen B, Christiansen M, and Wewer UM

Obstetrics and gynecology 106(1):144-9, 2005 Jul - Who cited this? | PubMed ID: 15994630 | Fulltext

A role for ADAM12 in breast tumor progression and stromal cell apoptosis.

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Kveiborg M, Fröhlich C, Albrechtsen R, Tischler V, Dietrich N, Holck P, Kronqvist P, Rank F, Mercurio AM, and Wewer UM

Cancer research 65(11):4754-61, 2005 Jun 1 - Who cited this? | PubMed ID: 15930294 | Fulltext

ADAM12 and alpha9beta1 integrin are instrumental in human myogenic cell differentiation.

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Lafuste P, Sonnet C, Chazaud B, Dreyfus PA, Gherardi RK, Wewer UM, and Authier FJ

Molecular biology of the cell 16(2):861-70, 2005 Feb - Who cited this? | PubMed ID: 15574885 | Fulltext

The level of ADAM12-S in maternal serum is an early first-trimester marker of fetal trisomy 18.

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Laigaard J, Christiansen M, Fröhlich C, Pedersen BN, Ottesen B, and Wewer UM

Prenatal diagnosis 25(1):45-6, 2005 Jan - Who cited this? | PubMed ID: 15662668 | Fulltext

Regulation of ADAM12 cell-surface expression by protein kinase C epsilon.

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Sundberg C, Thodeti CK, Kveiborg M, Larsson C, Parker P, Albrechtsen R, and Wewer UM

The Journal of biological chemistry 279(49):51601-11, 2004 Dec 3 - Who cited this? | PubMed ID: 15364951 | Fulltext

ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage.

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Roy R, Wewer UM, Zurakowski D, Pories SE, and Moses MA

The Journal of biological chemistry 279(49):51323-30, 2004 Dec 3 - Who cited this? | PubMed ID: 15381692 | Fulltext

Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice.

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Hansen TV, Hammer NA, Nielsen J, Madsen M, Dalbaeck C, Wewer UM, Christiansen J, and Nielsen FC

Molecular and cellular biology 24(10):4448-64, 2004 May - Who cited this? | PubMed ID: 15121863 | Fulltext

ADAM12: a novel first-trimester maternal serum marker for Down syndrome.

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Laigaard J, Sørensen T, Fröhlich C, Pedersen BN, Christiansen M, Schiøtt K, Uldbjerg N, Albrechtsen R, Clausen HV, Ottesen B, and Wewer UM

Prenatal diagnosis 23(13):1086-91, 2003 Dec 30 - Who cited this? | PubMed ID: 14691998 | Fulltext

ADAM12 induces actin cytoskeleton and extracellular matrix reorganization during early adipocyte differentiation by regulating beta1 integrin function.

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Kawaguchi N, Sundberg C, Kveiborg M, Moghadaszadeh B, Asmar M, Dietrich N, Thodeti CK, Nielsen FC, Möller P, Mercurio AM, Albrechtsen R, and Wewer UM

Journal of cell science 116(Pt 19):3893-904, 2003 Oct 1 - Who cited this? | PubMed ID: 12915587 | Fulltext

Compensation for dystrophin-deficiency: ADAM12 overexpression in skeletal muscle results in increased alpha 7 integrin, utrophin and associated glycoproteins.

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Moghadaszadeh B, Albrechtsen R, Guo LT, Zaik M, Kawaguchi N, Borup RH, Kronqvist P, Schroder HD, Davies KE, Voit T, Nielsen FC, Engvall E, and Wewer UM

Human molecular genetics 12(19):2467-79, 2003 Oct 1 - Who cited this? | PubMed ID: 12915458 | Fulltext

114th ENMC International Workshop on Congenital Muscular Dystrophy (CMD) 17-19 January 2003, Naarden, The Netherlands: (8th Workshop of the International Consortium on CMD; 3rd Workshop of the MYO-CLUSTER project GENRE).

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Muntoni F, Valero de Bernabe B, Bittner R, Blake D, van Bokhoven H, Brockington M, Brown S, Bushby K, Campbell KP, Fiszman M, Gruenewald S, Merlini L, Quijano-Roy S, Romero N, Sabatelli P, Sewry CA,

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Neuromuscular disorders : NMD 13(7-8):579-88, 2003 Sep - Who cited this? | PubMed ID: 12921796 | Fulltext

The new frontier in muscular dystrophy research: booster genes.

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Engvall E and Wewer UM

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 17(12):1579-84, 2003 Sep - Who cited this? | PubMed ID: 12958164 | Fulltext

Selenoprotein N: an endoplasmic reticulum glycoprotein with an early developmental expression pattern.

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Petit N, Lescure A, Rederstorff M, Krol A, Moghadaszadeh B, Wewer UM, and Guicheney P

Human molecular genetics 12(9):1045-53, 2003 May 1 - Who cited this? | PubMed ID: 12700173 | Fulltext

ADAM12 in human liver cancers: TGF-beta-regulated expression in stellate cells is associated with matrix remodeling.

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Le Pabic H, Bonnier D, Wewer UM, Coutand A, Musso O, Baffet G, Clément B, and Théret N

Hepatology (Baltimore, Md.) 37(5):1056-66, 2003 May - Who cited this? | PubMed ID: 12717386 | Fulltext

ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA.

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Thodeti CK, Albrechtsen R, Grauslund M, Asmar M, Larsson C, Takada Y, Mercurio AM, Couchman JR, and Wewer UM

The Journal of biological chemistry 278(11):9576, 2003 Mar 14 - Who cited this? | PubMed ID: 12509413 | Fulltext

Laminin alpha2 deficiency and muscular dystrophy; genotype-phenotype correlation in mutant mice.

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Guo LT, Zhang XU, Kuang W, Xu H, Liu LA, Vilquin JT, Miyagoe-Suzuki Y, Takeda S, Ruegg MA, Wewer UM, and Engvall E

Neuromuscular disorders : NMD 13(3):207-15, 2003 Mar - Who cited this? | PubMed ID: 12609502 | Fulltext

ADAM12 alleviates the skeletal muscle pathology in mdx dystrophic mice.

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Kronqvist P, Kawaguchi N, Albrechtsen R, Xu X, Schrøder HD, Moghadaszadeh B, Nielsen FC, Fröhlich C, Engvall E, and Wewer UM

The American journal of pathology 161(5):1535-40, 2002 Nov - Who cited this? | PubMed ID: 12414501 | Fulltext

ADAM 12 protease induces adipogenesis in transgenic mice.

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Kawaguchi N, Xu X, Tajima R, Kronqvist P, Sundberg C, Loechel F, Albrechtsen R, and Wewer UM

The American journal of pathology 160(5):1895-903, 2002 May - Who cited this? | PubMed ID: 12000741 | Fulltext

Mice with a targeted deletion of the tetranectin gene exhibit a spinal deformity.

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Iba K, Durkin ME, Johnsen L, Hunziker E, Damgaard-Pedersen K, Zhang H, Engvall E, Albrechtsen R, and Wewer UM

Molecular and cellular biology 21(22):7817-25, 2001 Nov - Who cited this? | PubMed ID: 11604516 | Fulltext

E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo.

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Porse BT, Pedersen TA, Xu X, Lindberg B, Wewer UM, Friis-Hansen L, and Nerlov C

Cell 107(2):247-58, 2001 Oct 19 - Who cited this? | PubMed ID: 11672531 | Fulltext

Activation of ADAM 12 protease by copper.

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Loechel F and Wewer UM

FEBS letters 506(1):65-8, 2001 Sep 28 - Who cited this? | PubMed ID: 11591372 | Fulltext

Regulation of laminin beta2 chain gene expression in human cancer cell lines.

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Durkin ME, Nielsen FC, Loechel F, Albrechtsen R, and Wewer UM

European journal of biochemistry / FEBS 268(13):3797-806, 2001 Jul - Who cited this? | PubMed ID: 11432748 | Fulltext

Tetranectin in slow intra- and extrafusal chicken muscle fibers.

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Xu X, Gilpin B, Iba K, Maier A, Engvall E, Albrechtsen R, and Wewer UM

Journal of muscle research and cell motility 22(2):121-32, 2001 - Who cited this? | PubMed ID: 11519735 | Fulltext

ADAM 12-S cleaves IGFBP-3 and IGFBP-5 and is inhibited by TIMP-3.

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Loechel F, Fox JW, Murphy G, Albrechtsen R, and Wewer UM

Biochemical and biophysical research communications 278(3):511-5, 2000 Nov 30 - Who cited this? | PubMed ID: 11095942 | Fulltext

H19 RNA binds four molecules of insulin-like growth factor II mRNA-binding protein.

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Runge S, Nielsen FC, Nielsen J, Lykke-Andersen J, Wewer UM, and Christiansen J

The Journal of biological chemistry 275(38):29562, 2000 Sep 22 - Who cited this? | PubMed ID: 10875929 | Fulltext

[Cell-matrix interactions in cancer].

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Wewer UM

Ugeskrift for laeger 162(36):4783-5, 2000 Sep 4 - Who cited this? | PubMed ID: 10994372 | Fulltext

Trafficking of human ADAM 12-L: retention in the trans-Golgi network.

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Hougaard S, Loechel F, Xu X, Tajima R, Albrechtsen R, and Wewer UM

Biochemical and biophysical research communications 275(2):261-7, 2000 Aug 28 - Who cited this? | PubMed ID: 10964655 | Fulltext

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