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Papers authored by Weitzmann MN

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The bone anabolic carotenoid beta-cryptoxanthin enhances transforming growth factor-beta1-induced SMAD activation in MC3T3 preosteoblasts.

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Yamaguchi M and Weitzmann MN

International journal of molecular medicine 24(5):671-5, 2009 Nov - Who cited this? | PubMed ID: 19787201 | Fulltext

A novel T cell cytokine, secreted osteoclastogenic factor of activated T cells, induces osteoclast formation in a RANKL-Independent manner.

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Rifas L and Weitzmann MN

Arthritis and rheumatism 60(11):3324-35, 2009 Nov - Who cited this? | PubMed ID: 19877052 | Fulltext

T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling.

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Terauchi M, Li JY, Bedi B, Baek KH, Tawfeek H, Galley S, Gilbert L, Nanes MS, Zayzafoon M, Guldberg R, Lamar DL, Singer MA, Lane TF, Kronenberg HM, Weitzmann MN, and Pacifici R

Cell metabolism 10(3):229-40, 2009 Sep - Who cited this? | PubMed ID: 19723499 | Fulltext

The estrogen 17beta-estradiol and phytoestrogen genistein mediate differential effects on osteoblastic NF-kappaB activity.

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Yamaguchi M and Weitzmann MN

International journal of molecular medicine 23(2):297-301, 2009 Feb - Who cited this? | PubMed ID: 19148557 | Fulltext

T cells potentiate PTH-induced cortical bone loss through CD40L signaling.

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Gao Y, Wu X, Terauchi M, Li JY, Grassi F, Galley S, Yang X, Weitzmann MN, and Pacifici R

Cell metabolism 8(2):132, 2008 Aug - Who cited this? | PubMed ID: 18680714 | Fulltext

Suppression of NF-kappaB activation blocks osteoclastic bone resorption during estrogen deficiency.

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Strait K, Li Y, Dillehay DL, and Weitzmann MN

International journal of molecular medicine 21(4):521, 2008 Apr - Who cited this? | PubMed ID: 18360699 | Fulltext

T cells: unexpected players in the bone loss induced by estrogen deficiency and in Basal bone homeostasis.

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Weitzmann MN and Pacifici R

Annals of the New York Academy of Sciences 1116:360-75, 2007 Dec - Who cited this? | PubMed ID: 18083938 | Fulltext

Oxidative stress causes bone loss in estrogen-deficient mice through enhanced bone marrow dendritic cell activation.

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Grassi F, Tell G, Robbie-Ryan M, Gao Y, Terauchi M, Yang X, Romanello M, Jones DP, Weitzmann MN, and Pacifici R

Proceedings of the National Academy of Sciences of the United States of America 104(38):15087-92, 2007 Sep 18 - Who cited this? | PubMed ID: 17848519 | Fulltext

Endogenous TNFalpha lowers maximum peak bone mass and inhibits osteoblastic Smad activation through NF-kappaB.

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Li Y, Li A, Strait K, Zhang H, Nanes MS, and Weitzmann MN

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 22(5):646-55, 2007 May - Who cited this? | PubMed ID: 17266397 | Fulltext

B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo.

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Li Y, Toraldo G, Li A, Yang X, Zhang H, Qian WP, and Weitzmann MN

Blood 109(9):3839-48, 2007 May 1 - Who cited this? | PubMed ID: 17202317 | Fulltext

Ovariectomy-induced bone loss occurs independently of B cells.

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Li Y, Li A, Yang X, and Weitzmann MN

Journal of cellular biochemistry 100(6):1370-5, 2007 Apr 15 - Who cited this? | PubMed ID: 17131364 | Fulltext

IFN-gamma stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation.

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Gao Y, Grassi F, Ryan MR, Terauchi M, Page K, Yang X, Weitzmann MN, and Pacifici R

The Journal of clinical investigation 117(1):122-32, 2007 Jan - Who cited this? | PubMed ID: 17173138 | Fulltext

Beta2-microglobulin promotes the growth of human renal cell carcinoma through the activation of the protein kinase A, cyclic AMP-responsive element-binding protein, and vascular endothelial growth factor axis.

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Nomura T, Huang WC, Zhau HE, Wu D, Xie Z, Mimata H, Zayzafoon M, Young AN, Marshall FF, Weitzmann MN, and Chung LW

Clinical cancer research : an official journal of the American Association for Cancer Research 12(24):7294, 2006 Dec 15 - Who cited this? | PubMed ID: 17189401 | Fulltext

beta2-microglobulin is a signaling and growth-promoting factor for human prostate cancer bone metastasis.

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Huang WC, Wu D, Xie Z, Zhau HE, Nomura T, Zayzafoon M, Pohl J, Hsieh CL, Weitzmann MN, Farach-Carson MC, and Chung LW

Cancer research 66(18):9108-16, 2006 Sep 15 - Who cited this? | PubMed ID: 16982753 | Fulltext

Bone re/modeling is more dynamic in the endothelial nitric oxide synthase(-/-) mouse.

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Grassi F, Fan X, Rahnert J, Weitzmann MN, Pacifici R, Nanes MS, and Rubin J

Endocrinology 147(9):4392, 2006 Sep - Who cited this? | PubMed ID: 16763060 | Fulltext

Estrogen deficiency and bone loss: an inflammatory tale.

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Weitzmann MN and Pacifici R

The Journal of clinical investigation 116(5):1186-94, 2006 May - Who cited this? | PubMed ID: 16670759 | Fulltext

Estrogen regulation of immune cell bone interactions.

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Weitzmann MN and Pacifici R

Annals of the New York Academy of Sciences 1068:256-74, 2006 Apr - Who cited this? | PubMed ID: 16831927 | Fulltext

IL-7 drives T cell-mediated bone loss following ovariectomy.

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Robbie-Ryan M, Pacifici R, and Weitzmann MN

Annals of the New York Academy of Sciences 1068:348-51, 2006 Apr - Who cited this? | PubMed ID: 16831936 | Fulltext

The role of T lymphocytes in bone metabolism.

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Weitzmann MN and Pacifici R

Immunological reviews 208:154-68, 2005 Dec - Who cited this? | PubMed ID: 16313347 | Fulltext

An IL-7-dependent rebound in thymic T cell output contributes to the bone loss induced by estrogen deficiency.

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Ryan MR, Shepherd R, Leavey JK, Gao Y, Grassi F, Schnell FJ, Qian WP, Kersh GJ, Weitzmann MN, and Pacifici R

Proceedings of the National Academy of Sciences of the United States of America 102(46):16735-40, 2005 Nov 15 - Who cited this? | PubMed ID: 16267136 | Fulltext

Role of the immune system in postmenopausal bone loss.

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Weitzmann MN and Pacifici R

Current osteoporosis reports 3(3):92-7, 2005 Sep - Who cited this? | PubMed ID: 16131428 | Fulltext

Estrogen prevents bone loss through transforming growth factor beta signaling in T cells.

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Gao Y, Qian WP, Dark K, Toraldo G, Lin AS, Guldberg RE, Flavell RA, Weitzmann MN, and Pacifici R

Proceedings of the National Academy of Sciences of the United States of America 101(47):16618-23, 2004 Nov 23 - Who cited this? | PubMed ID: 15531637 | Fulltext

Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-gamma-induced class II transactivator.

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Cenci S, Toraldo G, Weitzmann MN, Roggia C, Gao Y, Qian WP, Sierra O, and Pacifici R

Proceedings of the National Academy of Sciences of the United States of America 100(18):10405-10, 2003 Sep 2 - Who cited this? | PubMed ID: 12923292 | Fulltext

Inflammatory T cells rapidly induce differentiation of human bone marrow stromal cells into mature osteoblasts.

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Rifas L, Arackal S, and Weitzmann MN

Journal of cellular biochemistry 88(4):650-9, 2003 Mar 1 - Who cited this? | PubMed ID: 12577299 | Fulltext

IL-7 induces bone loss in vivo by induction of receptor activator of nuclear factor kappa B ligand and tumor necrosis factor alpha from T cells.

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Toraldo G, Roggia C, Qian WP, Pacifici R, and Weitzmann MN

Proceedings of the National Academy of Sciences of the United States of America 100(1):125-30, 2003 Jan 7 - Who cited this? | PubMed ID: 12490655 | Fulltext

Increased production of IL-7 uncouples bone formation from bone resorption during estrogen deficiency.

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Weitzmann MN, Roggia C, Toraldo G, Weitzmann L, and Pacifici R

The Journal of clinical investigation 110(11):1643-50, 2002 Dec - Who cited this? | PubMed ID: 12464669 | Fulltext

Up-regulation of TNF-producing T cells in the bone marrow: a key mechanism by which estrogen deficiency induces bone loss in vivo.

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Roggia C, Gao Y, Cenci S, Weitzmann MN, Toraldo G, Isaia G, and Pacifici R

Proceedings of the National Academy of Sciences of the United States of America 98(24):13960-5, 2001 Nov 20 - Who cited this? | PubMed ID: 11717453 | Fulltext

Estrogen decreases osteoclast formation by down-regulating receptor activator of NF-kappa B ligand (RANKL)-induced JNK activation.

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Srivastava S, Toraldo G, Weitzmann MN, Cenci S, Ross FP, and Pacifici R

The Journal of biological chemistry 276(12):8836-40, 2001 Mar 23 - Who cited this? | PubMed ID: 11121427 | Fulltext

T cell activation induces human osteoclast formation via receptor activator of nuclear factor kappaB ligand-dependent and -independent mechanisms.

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Weitzmann MN, Cenci S, Rifas L, Haug J, Dipersio J, and Pacifici R

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 16(2):328-37, 2001 Feb - Who cited this? | PubMed ID: 11204433 | Fulltext

Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha.

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Cenci S, Weitzmann MN, Roggia C, Namba N, Novack D, Woodring J, and Pacifici R

The Journal of clinical investigation 106(10):1229-37, 2000 Nov - Who cited this? | PubMed ID: 11086024 | Fulltext

Interleukin-7 stimulates osteoclast formation by up-regulating the T-cell production of soluble osteoclastogenic cytokines.

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Weitzmann MN, Cenci S, Rifas L, Brown C, and Pacifici R

Blood 96(5):1873-8, 2000 Sep 1 - Who cited this? | PubMed ID: 10961889 | Fulltext

M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss.

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Cenci S, Weitzmann MN, Gentile MA, Aisa MC, and Pacifici R

The Journal of clinical investigation 105(9):1279-87, 2000 May - Who cited this? | PubMed ID: 10792003 | Fulltext

B lymphocytes inhibit human osteoclastogenesis by secretion of TGFbeta.

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Weitzmann MN, Cenci S, Haug J, Brown C, DiPersio J, and Pacifici R

Journal of cellular biochemistry 78(2):318-24, 2000 May - Who cited this? | PubMed ID: 10842325 | Fulltext

Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD.

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Srivastava S, Weitzmann MN, Cenci S, Ross FP, Adler S, and Pacifici R

The Journal of clinical investigation 104(4):503-13, 1999 Aug - Who cited this? | PubMed ID: 10449442 | Fulltext

Estrogen blocks M-CSF gene expression and osteoclast formation by regulating phosphorylation of Egr-1 and its interaction with Sp-1.

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Srivastava S, Weitzmann MN, Kimble RB, Rizzo M, Zahner M, Milbrandt J, Ross FP, and Pacifici R

The Journal of clinical investigation 102(10):1850-9, 1998 Nov 15 - Who cited this? | PubMed ID: 9819371 | Fulltext

The mouse Ms6-hm hypervariable microsatellite forms a hairpin and two unusual tetraplexes.

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Weitzmann MN, Woodford KJ, and Usdin K

The Journal of biological chemistry 273(46):30742-9, 1998 Nov 13 - Who cited this? | PubMed ID: 9804850 | Fulltext

DNA secondary structures and the evolution of hypervariable tandem arrays.

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Weitzmann MN, Woodford KJ, and Usdin K

The Journal of biological chemistry 272(14):9517-23, 1997 Apr 4 - Who cited this? | PubMed ID: 9083093 | Fulltext

The development and use of a DNA polymerase arrest assay for the evaluation of parameters affecting intrastrand tetraplex formation.

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Weitzmann MN, Woodford KJ, and Usdin K

The Journal of biological chemistry 271(34):20958-64, 1996 Aug 23 - Who cited this? | PubMed ID: 8702855 | Fulltext

The chicken beta-globin gene promoter forms a novel "cinched" tetrahelical structure.

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Howell RM, Woodford KJ, Weitzmann MN, and Usdin K

The Journal of biological chemistry 271(9):5208-14, 1996 Mar 1 - Who cited this? | PubMed ID: 8617804 | Fulltext

The use of K(+)-free buffers eliminates a common cause of premature chain termination in PCR and PCR sequencing.

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Woodford K, Weitzmann MN, and Usdin K

Nucleic acids research 23(3):539, 1995 Feb 11 - Who cited this? | PubMed ID: 7885853 | Fulltext

Cloning of an antibody binding DNA sequence: pitfalls of DNA/protein immunoprecipitation reactions.

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Weitzmann MN and Savage N

Journal of immunological methods 173(1):7-10, 1994 Jul 12 - Who cited this? | PubMed ID: 8034988 | Fulltext

Cyclic adenosine 3',5'-monophosphate, a second messenger in interleukin-1 mediated K562 cytostasis.

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Weitzmann MN and Savage N

Biochemical and biophysical research communications 190(2):564-70, 1993 Jan 29 - Who cited this? | PubMed ID: 8381280 | Fulltext

Failure of interleukin-1 to induce intracellular calcium fluxes in K562 cells.

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Weitzmann MN and Savage N

Life sciences 53(6):PL95-7, 1993 - Who cited this? | PubMed ID: 8393508 | Fulltext

Nuclear internalisation and DNA binding activities of interleukin-1, interleukin-1 receptor and interleukin-1/receptor complexes.

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Weitzmann MN and Savage N

Biochemical and biophysical research communications 187(2):1166-71, 1992 Sep 16 - Who cited this? | PubMed ID: 1388356 | Fulltext

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