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Papers authored by Varadarajan R

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Metachronous and synchronous presentation of acute myeloid leukemia and lung cancer.

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Varadarajan R, Ford L, Sait SN, Block AW, Barcos M, Wallace PK, Ramnath N, Wang ES, and Wetzler M

Leukemia research 33(9):1208-11, 2009 Sep - Who cited this? | PubMed ID: 19181380 | Fulltext

Effect of Crowding Agents, Signal Peptide, and Chaperone SecB on the Folding and Aggregation of E. coli Maltose Binding Protein.

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Kulothungan SR, Das M, Johnson M, Ganesh C, and Varadarajan R

Langmuir : the ACS journal of surfaces and colloids 25(12):6637-48, 2009 Jun 16 - Who cited this? | PubMed ID: 19358587 | Fulltext

SecB-Mediated Protein Export Need Not Occur via Kinetic Partitioning.

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Krishnan B, Kulothungan SR, Patra AK, Udgaonkar JB, and Varadarajan R

Journal of molecular biology 385(4):1243-56, 2009 Jan 30 - Who cited this? | PubMed ID: 19028503 | Fulltext

Structural Correlates of the Temperature Sensitive Phenotype Derived from Saturation Mutagenesis Studies of CcdB (dagger).

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Bajaj K, Dewan PC, Chakrabarti P, Goswami D, Barua B, Baliga C, and Varadarajan R

Biochemistry 47(49):12964-73, 2008 Dec 9 - Who cited this? | PubMed ID: 19006334 | Fulltext

Refolding and simultaneous purification by three-phase partitioning of recombinant proteins from inclusion bodies.

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Raghava S, Barua B, Singh PK, Das M, Madan L, Bhattacharyya S, Bajaj K, Gopal B, Varadarajan R, and Gupta MN

Protein science : a publication of the Protein Society 17(11):1987-97, 2008 Nov - Who cited this? | PubMed ID: 18780821 | Fulltext

Design and utility of temperature-sensitive gal4 mutants for conditional gene expression in Drosophila.

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Mondal K, Vijayraghavan K, and Varadarajan R

Fly 1(5):282-6 - Who cited this? | PubMed ID: 18836309 | Fulltext

Strategy for purifying maltose binding protein fusion proteins by affinity precipitation.

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Raghava S, Aquil S, Bhattacharyya S, Varadarajan R, and Gupta MN

Journal of chromatography. A 1194(1):90-5, 2008 Jun 13 - Who cited this? | PubMed ID: 18466911 | Fulltext

Comparison of two error-detection methods in a mail service pharmacy serving health facilities.

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Varadarajan R, Barker KN, Flynn EA, and Thomas RE

Journal of the American Pharmacists Association : JAPhA 48(3):371-8, 2008 - Who cited this? | PubMed ID: 18595822 | Fulltext

Stereochemical criteria for prediction of the effects of proline mutations on protein stability.

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Bajaj K, Madhusudhan MS, Adkar BV, Chakrabarti P, Ramakrishnan C, Sali A, and Varadarajan R

PLoS computational biology 3(12):e241, 2007 Dec - Who cited this? | PubMed ID: 18069886 | Fulltext

Design of disulfide-linked thioredoxin dimers and multimers through analysis of crystal contacts.

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Das M, Kobayashi M, Yamada Y, Sreeramulu S, Ramakrishnan C, Wakatsuki S, Kato R, and Varadarajan R

Journal of molecular biology 372(5):1278-92, 2007 Oct 5 - Who cited this? | PubMed ID: 17727880 | Fulltext

Identification and thermodynamic characterization of molten globule states of periplasmic binding proteins.

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Prajapati RS, Indu S, and Varadarajan R

Biochemistry 46(36):10339-52, 2007 Sep 11 - Who cited this? | PubMed ID: 17696409 | Fulltext

The prevalence of disorders of haemostasis in adolescents with menorrhagia referred to a haemophilia treatment centre.

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Mikhail S, Varadarajan R, and Kouides P

Haemophilia : the official journal of the World Federation of Hemophilia 13(5):627-32, 2007 Sep - Who cited this? | PubMed ID: 17880454 | Fulltext

Design and isolation of temperature-sensitive mutants of Gal4 in yeast and Drosophila.

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Mondal K, Dastidar AG, Singh G, Madhusudhanan S, Gande SL, VijayRaghavan K, and Varadarajan R

Journal of molecular biology 370(5):939-50, 2007 Jul 27 - Who cited this? | PubMed ID: 17553522 | Fulltext

Thermodynamic effects of proline introduction on protein stability.

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Prajapati RS, Das M, Sreeramulu S, Sirajuddin M, Srinivasan S, Krishnamurthy V, Ranjani R, Ramakrishnan C, and Varadarajan R

Proteins 66(2):480-91, 2007 Feb 1 - Who cited this? | PubMed ID: 17034035 | Fulltext

Role of stimuli-sensitive polymers in protein refolding: alpha-amylase and CcdB (controller of cell division or death B) as model proteins.

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Mondal K, Raghava S, Barua B, Varadarajan R, and Gupta MN

Langmuir : the ACS journal of surfaces and colloids 23(1):70-5, 2007 Jan 2 - Who cited this? | PubMed ID: 17190487 | Fulltext

Specialty dentistry for the hemophiliac: is there a protocol in place?.

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Kumar JN, Kumar RA, Varadarajan R, and Sharma N

Indian journal of dental research : official publication of Indian Society for Dental Research 18(2):48-54, 2007 - Who cited this? | PubMed ID: 17502707 | Fulltext

Contribution of cation-pi interactions to protein stability.

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Prajapati RS, Sirajuddin M, Durani V, Sreeramulu S, and Varadarajan R

Biochemistry 45(50):15000-10, 2006 Dec 19 - Who cited this? | PubMed ID: 17154537 | Fulltext

Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia-reperfusion injury.

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Leonard MO, Kieran NE, Howell K, Burne MJ, Varadarajan R, Dhakshinamoorthy S, Porter AG, O'Farrelly C, Rabb H, and Taylor CT

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20(14):2624-6, 2006 Dec - Who cited this? | PubMed ID: 17142801 | Fulltext

Design of immunogens that present the crown of the HIV-1 V3 loop in a conformation competent to generate 447-52D-like antibodies.

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Chakraborty K, Durani V, Miranda ER, Citron M, Liang X, Schleif W, Joyce JG, and Varadarajan R

The Biochemical journal 399(3):483-91, 2006 Nov 1 - Who cited this? | PubMed ID: 16827663 | Fulltext

Compliance calibration for fatigue crack propagation testing of ultra high molecular weight polyethylene.

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Varadarajan R and Rimnac CM

Biomaterials 27(27):4693-7, 2006 Sep - Who cited this? | PubMed ID: 16750266 | Fulltext

Prognosis of occult breast carcinoma presenting as isolated axillary nodal metastasis.

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Varadarajan R, Edge SB, Yu J, Watroba N, and Janarthanan BR

Oncology 71(5-6):456-9, 2006 - Who cited this? | PubMed ID: 17690561 | Fulltext

Protein minimization of the gp120 binding region of human CD4.

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Sharma D, Balamurali MM, Chakraborty K, Kumaran S, Jeganathan S, Rashid U, Ingallinella P, and Varadarajan R

Biochemistry 44(49):16192-202, 2005 Dec 13 - Who cited this? | PubMed ID: 16331979 | Fulltext

Protein stabilization by introduction of cross-strand disulfides.

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Chakraborty K, Thakurela S, Prajapati RS, Indu S, Ali PS, Ramakrishnan C, and Varadarajan R

Biochemistry 44(44):14638-46, 2005 Nov 8 - Who cited this? | PubMed ID: 16262263 | Fulltext

Mutagenesis-based definitions and probes of residue burial in proteins.

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Bajaj K, Chakrabarti P, and Varadarajan R

Proceedings of the National Academy of Sciences of the United States of America 102(45):16221-6, 2005 Nov 8 - Who cited this? | PubMed ID: 16251276 | Fulltext

Utilization of extended donor criteria liver allografts maximizes donor use and patient access to liver transplantation.

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Renz JF, Kin C, Kinkhabwala M, Jan D, Varadarajan R, Goldstein M, Brown R, and Emond JC

Annals of surgery 242(4):556-63; discussion 563-5, 2005 Oct - Who cited this? | PubMed ID: 16192816 | Fulltext

NMR structural analysis of a peptide mimic of the bridging sheet of HIV-1 gp120 in methanol and water.

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Chakraborty K, Shivakumar P, Raghothama S, and Varadarajan R

The Biochemical journal 390(Pt 2):573-81, 2005 Sep 1 - Who cited this? | PubMed ID: 15896194 | Fulltext

Attempts to delineate the relative contributions of changes in hydrophobicity and packing to changes in stability of ribonuclease S mutants.

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Das M, Rao BV, Ghosh S, and Varadarajan R

Biochemistry 44(15):5923-30, 2005 Apr 19 - Who cited this? | PubMed ID: 15823052 | Fulltext

Characterization of gp120 and its single-chain derivatives, gp120-CD4D12 and gp120-M9: implications for targeting the CD4i epitope in human immunodeficiency virus vaccine design.

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Varadarajan R, Sharma D, Chakraborty K, Patel M, Citron M, Sinha P, Yadav R, Rashid U, Kennedy S, Eckert D, Geleziunas R, Bramhill D, Schleif W, Liang X, and Shiver J

Journal of virology 79(3):1713-23, 2005 Feb - Who cited this? | PubMed ID: 15650196 | Fulltext

Accurate detection of protein:ligand binding sites using molecular dynamics simulations.

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Bhinge A, Chakrabarti P, Uthanumallian K, Bajaj K, Chakraborty K, and Varadarajan R

Structure (London, England : 1993) 12(11):1989-99, 2004 Nov - Who cited this? | PubMed ID: 15530363 | Fulltext

Nitric oxide in early ischaemia reperfusion injury during human orthotopic liver transplantation.

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Varadarajan R, Golden-Mason L, Young L, McLoughlin P, Nolan N, McEntee G, Traynor O, Geoghegan J, Hegarty JE, and O'Farrelly C

Transplantation 78(2):250-6, 2004 Jul 27 - Who cited this? | PubMed ID: 15280686 | Fulltext

Thermodynamic characterization of monomeric and dimeric forms of CcdB (controller of cell division or death B protein).

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Bajaj K, Chakshusmathi G, Bachhawat-Sikder K, Surolia A, and Varadarajan R

The Biochemical journal 380(Pt 2):409-17, 2004 Jun 1 - Who cited this? | PubMed ID: 14763902 | Fulltext

Design of temperature-sensitive mutants solely from amino acid sequence.

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Chakshusmathi G, Mondal K, Lakshmi GS, Singh G, Roy A, Ch RB, Madhusudhanan S, and Varadarajan R

Proceedings of the National Academy of Sciences of the United States of America 101(21):7925, 2004 May 25 - Who cited this? | PubMed ID: 15148363 | Fulltext

Effect of signal peptide on the stability and folding kinetics of maltose binding protein.

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Beena K, Udgaonkar JB, and Varadarajan R

Biochemistry 43(12):3608, 2004 Mar 30 - Who cited this? | PubMed ID: 15035631 | Fulltext

Rituximab administration following autologous stem cell transplantation for multiple myeloma is associated with severe IgM deficiency.

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Lim SH, Zhang Y, Wang Z, Varadarajan R, Periman P, and Esler WV

Blood 103(5):1971-2, 2004 Mar 1 - Who cited this? | PubMed ID: 14976066 | Fulltext

Umbilical cord blood transplant in hepatitis C-associated severe aplastic anemia.

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Lim SH, Zhang Y, Wang Z, Varadarajan R, Smith P, Burris C, and Townsend M

Bone marrow transplantation 33(5):565-7, 2004 Mar - Who cited this? | PubMed ID: 14688818 | Fulltext

Thermodynamic effects of replacements of Pro residues in helix interiors of maltose-binding protein.

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Prajapati RS, Lingaraju GM, Bacchawat K, Surolia A, and Varadarajan R

Proteins 53(4):863-71, 2003 Dec 1 - Who cited this? | PubMed ID: 14635128 | Fulltext

A gradient PCR-based screen for use in site-directed mutagenesis.

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Padmakumar VC and Varadarajan R

Analytical biochemistry 314(2):310-5, 2003 Mar 15 - Who cited this? | PubMed ID: 12654318 | Fulltext

MODIP revisited: re-evaluation and refinement of an automated procedure for modeling of disulfide bonds in proteins.

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Dani VS, Ramakrishnan C, and Varadarajan R

Protein engineering 16(3):187-93, 2003 Mar - Who cited this? | PubMed ID: 12702798 | Fulltext

Accessory left biliary duct draining into the lesser curve of the stomach.

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Mascarenhas R, Varadarajan R, Mathias J, Traynor O, and Geoghegan J

Gut 51(6):884, 2002 Dec - Who cited this? | PubMed ID: 12427795 | Fulltext

A procedure for detection and quantitation of cavity volumes proteins. Application to measure the strength of the hydrophobic driving force in protein folding.

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Chakravarty S, Bhinge A, and Varadarajan R

The Journal of biological chemistry 277(35):31345-53, 2002 Aug 30 - Who cited this? | PubMed ID: 12070144 | Fulltext

Structural consequences of replacement of an alpha-helical Pro residue in Escherichia coli thioredoxin.

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Rudresh, Jain R, Dani V, Mitra A, Srivastava S, Sarma SP, Varadarajan R, and Ramakumar S

Protein engineering 15(8):627-33, 2002 Aug - Who cited this? | PubMed ID: 12364576 | Fulltext

Elucidation of factors responsible for enhanced thermal stability of proteins: a structural genomics based study.

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Chakravarty S and Varadarajan R

Biochemistry 41(25):8152-61, 2002 Jun 25 - Who cited this? | PubMed ID: 12069608 | Fulltext

Spontaneous hepatic rupture: a report of five cases.

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Mascarenhas R, Mathias J, Varadarajan R, Geoghegan J, and Traynor O

HPB : the official journal of the International Hepato Pancreato Biliary Association 4(4):167-70, 2002 - Who cited this? | PubMed ID: 18332948 | Fulltext

Electron spin resonance and fluorescence studies of the bound-state conformation of a model protein substrate to the chaperone SecB.

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Panse VG, Beena K, Philipp R, Trommer WE, Vogel PD, and Varadarajan R

The Journal of biological chemistry 276(36):33681-8, 2001 Sep 7 - Who cited this? | PubMed ID: 11435433 | Fulltext

Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states.

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Ratnaparkhi GS and Varadarajan R

The Journal of biological chemistry 276(31):28789-98, 2001 Aug 3 - Who cited this? | PubMed ID: 11373282 | Fulltext

Reversible formation of on-pathway macroscopic aggregates during the folding of maltose binding protein.

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Ganesh C, Zaidi FN, Udgaonkar JB, and Varadarajan R

Protein science : a publication of the Protein Society 10(8):1635-44, 2001 Aug - Who cited this? | PubMed ID: 11468360 | Fulltext

Thermodynamic and structural studies of cavity formation in proteins suggest that loss of packing interactions rather than the hydrophobic effect dominates the observed energetics.

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Ratnaparkhi GS and Varadarajan R

Biochemistry 39(40):12365-74, 2000 Oct 10 - Who cited this? | PubMed ID: 11015216 | Fulltext

Structural and thermodynamic consequences of introducing alpha-aminoisobutyric acid in the S peptide of ribonuclease S.

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Ratnaparkhi GS, Awasthi SK, Rani P, Balaram P, and Varadarajan R

Protein engineering 13(10):697-702, 2000 Oct - Who cited this? | PubMed ID: 11112508 | Fulltext

Protein stabilization through phage display.

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Chakravarty S, Mitra N, Queitsch I, Surolia A, Varadarajan R, and Dübel S

FEBS letters 476(3):296-300, 2000 Jul 7 - Who cited this? | PubMed ID: 10913631 | Fulltext

A thermodynamic coupling mechanism for the disaggregation of a model peptide substrate by chaperone secB.

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Panse VG, Vogel P, Trommer WE, and Varadarajan R

The Journal of biological chemistry 275(25):18698-703, 2000 Jun 23 - Who cited this? | PubMed ID: 10858444 | Fulltext

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