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Papers authored by Vander Heiden MG

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Understanding the Warburg effect: the metabolic requirements of cell proliferation.

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Vander Heiden MG, Cantley LC, and Thompson CB

Science (New York, N.Y.) 324(5930):1029-33, 2009 May 22 - Who cited this? | PubMed ID: 19460998 | Fulltext

Biomolecular characterization and protein sequences of the Campanian hadrosaur B. canadensis.

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Schweitzer MH, Zheng W, Organ CL, Avci R, Suo Z, Freimark LM, Lebleu VS, Duncan MB, Vander Heiden MG, Neveu JM, Lane WS, Cottrell JS, Horner JR, Cantley LC, Kalluri R, and Asara JM

Science (New York, N.Y.) 324(5927):626-31, 2009 May 1 - Who cited this? | PubMed ID: 19407199 | Fulltext

Pyruvate kinase M2 is a phosphotyrosine-binding protein.

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Christofk HR, Vander Heiden MG, Wu N, Asara JM, and Cantley LC

Nature 452(7184):181, 2008 Mar 13 - Who cited this? | PubMed ID: 18337815 | Fulltext

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.

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Christofk HR, Vander Heiden MG, Harris MH, Ramanathan A, Gerszten RE, Wei R, Fleming MD, Schreiber SL, and Cantley LC

Nature 452(7184):230, 2008 Mar 13 - Who cited this? | PubMed ID: 18337823 | Fulltext

Caspase-9 is activated in a cytochrome c-independent manner early during TNFalpha-induced apoptosis in murine cells.

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McDonnell MA, Wang D, Khan SM, Vander Heiden MG, and Kelekar A

Cell death and differentiation 10(9):1005-15, 2003 Sep - Who cited this? | PubMed ID: 12934075 | Fulltext

Bcl-x(L) complements Saccharomyces cerevisiae genes that facilitate the switch from glycolytic to oxidative metabolism.

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Vander Heiden MG, Choy JS, VanderWeele DJ, Brace JL, Harris MH, Bauer DE, Prange B, Kron SJ, Thompson CB, and Rudin CM

The Journal of biological chemistry 277(47):44870-6, 2002 Nov 22 - Who cited this? | PubMed ID: 12244097 | Fulltext

Genotoxic exposure is associated with alterations in glucose uptake and metabolism.

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Zhou R, Vander Heiden MG, and Rudin CM

Cancer research 62(12):3515-20, 2002 Jun 15 - Who cited this? | PubMed ID: 12067998 | Fulltext

Growth factors can influence cell growth and survival through effects on glucose metabolism.

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Vander Heiden MG, Plas DR, Rathmell JC, Fox CJ, Harris MH, and Thompson CB

Molecular and cellular biology 21(17):5899-912, 2001 Sep - Who cited this? | PubMed ID: 11486029 | Fulltext

Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane.

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Vander Heiden MG, Li XX, Gottleib E, Hill RB, Thompson CB, and Colombini M

The Journal of biological chemistry 276(22):19414-9, 2001 Jun 1 - Who cited this? | PubMed ID: 11259441 | Fulltext

The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A.

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Chuang E, Fisher TS, Morgan RW, Robbins MD, Duerr JM, Vander Heiden MG, Gardner JP, Hambor JE, Neveu MJ, and Thompson CB

Immunity 13(3):313-22, 2000 Sep - Who cited this? | PubMed ID: 11021529 | Fulltext

In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability.

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Rathmell JC, Vander Heiden MG, Harris MH, Frauwirth KA, and Thompson CB

Molecular cell 6(3):683-92, 2000 Sep - Who cited this? | PubMed ID: 11030347 | Fulltext

Redox regulation of p53 during hypoxia.

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Chandel NS, Vander Heiden MG, Thompson CB, and Schumacker PT

Oncogene 19(34):3840-8, 2000 Aug 10 - Who cited this? | PubMed ID: 10951577 | Fulltext

Bcl-x(L) prevents the initial decrease in mitochondrial membrane potential and subsequent reactive oxygen species production during tumor necrosis factor alpha-induced apoptosis.

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Gottlieb E, Vander Heiden MG, and Thompson CB

Molecular and cellular biology 20(15):5680-9, 2000 Aug - Who cited this? | PubMed ID: 10891504 | Fulltext

Role of oxidative phosphorylation in Bax toxicity.

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Harris MH, Vander Heiden MG, Kron SJ, and Thompson CB

Molecular and cellular biology 20(10):3590-6, 2000 May - Who cited this? | PubMed ID: 10779348 | Fulltext

Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival.

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Vander Heiden MG, Chandel NS, Li XX, Schumacker PT, Colombini M, and Thompson CB

Proceedings of the National Academy of Sciences of the United States of America 97(9):4666-71, 2000 Apr 25 - Who cited this? | PubMed ID: 10781072 | Fulltext

Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?.

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Vander Heiden MG and Thompson CB

Nature cell biology 1(8):E209-16, 1999 Dec - Who cited this? | PubMed ID: 10587660 | Fulltext

Bcl-xL regulates apoptosis by heterodimerization-dependent and -independent mechanisms.

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Minn AJ, Kettlun CS, Liang H, Kelekar A, Vander Heiden MG, Chang BS, Fesik SW, Fill M, and Thompson CB

The EMBO journal 18(3):632-43, 1999 Feb 1 - Who cited this? | PubMed ID: 9927423 | Fulltext

Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange.

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Vander Heiden MG, Chandel NS, Schumacker PT, and Thompson CB

Molecular cell 3(2):159-67, 1999 Feb - Who cited this? | PubMed ID: 10078199 | Fulltext

What keeps a resting T cell alive?.

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Thompson CB, Rathmell JC, Frauwirth KA, Lindsten T, Rudin CM, Opferman JT, Ashton-Rickardt PG, Harris MH, Chandel NS, Schumacker PT, and Vander Heiden MG

Cold Spring Harbor symposia on quantitative biology 64:383-7, 1999 - Who cited this? | PubMed ID: 11232311 | Fulltext

Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria.

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Vander Heiden MG, Chandel NS, Williamson EK, Schumacker PT, and Thompson CB

Cell 91(5):627-37, 1997 Nov 28 - Who cited this? | PubMed ID: 9393856 | Fulltext

Interaction of CTLA-4 with the clathrin-associated protein AP50 results in ligand-independent endocytosis that limits cell surface expression.

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Chuang E, Alegre ML, Duckett CS, Noel PJ, Vander Heiden MG, and Thompson CB

Journal of immunology (Baltimore, Md. : 1950) 159(1):144-51, 1997 Jul 1 - Who cited this? | PubMed ID: 9200449 | Fulltext

Identification of domains in an Arabidopsis acyl carrier protein gene promoter required for maximal organ-specific expression.

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Baerson SR, Vander Heiden MG, and Lamppa GK

Plant molecular biology 26(6):1947-59, 1994 Dec - Who cited this? | PubMed ID: 7858229 | Fulltext

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Papers authored by Vander Heiden MG

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