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Papers authored by Van Den Berg WB

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Computational design and application of endogenous promoters for transcriptionally targeted gene therapy for rheumatoid arthritis.

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Geurts J, Joosten LA, Takahashi N, Arntz OJ, Glück A, Bennink MB, van den Berg WB, and van de Loo FA

Molecular therapy : the journal of the American Society of Gene Therapy 17(11):1877-87, 2009 Nov - Who cited this? | PubMed ID: 19690516 | Fulltext

Local interleukin-1-driven joint pathology is dependent on toll-like receptor 4 activation.

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Abdollahi-Roodsaz S, Joosten LA, Koenders MI, van den Brand BT, van de Loo FA, and van den Berg WB

The American journal of pathology 175(5):2004-13, 2009 Nov - Who cited this? | PubMed ID: 19834062 | Fulltext

Attenuated atherosclerosis upon IL-17R signaling disruption in LDLr deficient mice.

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van Es T, van Puijvelde GH, Ramos OH, Segers FM, Joosten LA, van den Berg WB, Michon IM, de Vos P, van Berkel TJ, and Kuiper J

Biochemical and biophysical research communications 388(2):261-5, 2009 Oct 16 - Who cited this? | PubMed ID: 19660432 | Fulltext

The Inhibitory Fc{gamma}IIb Receptor Dampens TLR4-Mediated Immune Responses and Is Selectively Up-regulated on Dendritic Cells from Rheumatoid Arthritis Patients with Quiescent Disease.

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Wenink MH, Santegoets KC, Roelofs MF, Huijbens R, Koenen HJ, van Beek R, Joosten I, Meyer-Wentrup F, Mathsson L, Ronnelid J, Adema GJ, Bonvini E, Koenig S, van den Berg WB, van Riel PL, and Radstake TR

Journal of immunology (Baltimore, Md. : 1950) 183(7):4509-20, 2009 Oct 1 - Who cited this? | PubMed ID: 19734236 | Fulltext

IL-17 as a future therapeutic target for rheumatoid arthritis.

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van den Berg WB and Miossec P

Nature reviews. Rheumatology 5(10):549-53, 2009 Oct - Who cited this? | PubMed ID: 19798029 | Fulltext

Scavenger receptor class A type I/II determines matrix metalloproteinase-mediated cartilage destruction and chondrocyte death in antigen-induced arthritis.

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van Lent PL, Hofkens W, Blom AB, Grevers L, Sloetjes A, Takahashi N, van Tits LJ, Vogl T, Roth J, de Winther MP, and van den Berg WB

Arthritis and rheumatism 60(10):2954-65, 2009 Oct - Who cited this? | PubMed ID: 19790077 | Fulltext

Inflammatory role of ASC in antigen-induced arthritis is independent of caspase-1, NALP-3, and IPAF.

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Kolly L, Karababa M, Joosten LA, Narayan S, Salvi R, Pétrilli V, Tschopp J, van den Berg WB, So AK, and Busso N

Journal of immunology (Baltimore, Md. : 1950) 183(6):4003-12, 2009 Sep 15 - Who cited this? | PubMed ID: 19717512 | Fulltext

CHECK (Cohort Hip and Cohort Knee): similarities and differences with the Osteoarthritis Initiative.

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Wesseling J, Dekker J, van den Berg WB, Bierma-Zeinstra SM, Boers M, Cats HA, Deckers P, Gorter KJ, Heuts PH, Hilberdink WK, Kloppenburg M, Nelissen RG, Oosterveld FG, Oostveen JC, Roorda LD, Viergever MA,

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Annals of the rheumatic diseases 68(9):1413-9, 2009 Sep - Who cited this? | PubMed ID: 18772189 | Fulltext

Increase in ALK1/ALK5 Ratio as a Cause for Elevated MMP-13 Expression in Osteoarthritis in Humans and Mice.

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Blaney Davidson EN, Remst DF, Vitters EL, van Beuningen HM, Blom AB, Goumans MJ, van den Berg WB, and van der Kraan PM

Journal of immunology (Baltimore, Md. : 1950) 182(12):7937-45, 2009 Jun 15 - Who cited this? | PubMed ID: 19494318 | Fulltext

Combined blockade of granulocyte-macrophage colony stimulating factor and interleukin 17 pathways potently suppresses chronic destructive arthritis in a tumour necrosis factor alpha-independent mouse model.

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Plater-Zyberk C, Joosten LA, Helsen MM, Koenders MI, Baeuerle PA, and van den Berg WB

Annals of the rheumatic diseases 68(5):721-8, 2009 May - Who cited this? | PubMed ID: 18495731 | Fulltext

The Macrophage Mannose Receptor Induces IL-17 in Response to Candida albicans.

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van de Veerdonk FL, Marijnissen RJ, Kullberg BJ, Koenen HJ, Cheng SC, Joosten I, van den Berg WB, Williams DL, van der Meer JW, Joosten LA, and Netea MG

Cell host & microbe 5(4):329-40, 2009 Apr 23 - Who cited this? | PubMed ID: 19380112 | Fulltext

Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: Prominent role of Wnt-induced signaling protein 1.

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Blom AB, Brockbank SM, van Lent PL, van Beuningen HM, Geurts J, Takahashi N, van der Kraan PM, van de Loo FA, Schreurs BW, Clements K, Newham P, and van den Berg WB

Arthritis and rheumatism 60(2):501-12, 2009 Feb - Who cited this? | PubMed ID: 19180479 | Fulltext

Different amplifying mechanisms of interleukin-17 and interferon-gamma in Fcgamma receptor-mediated cartilage destruction in murine immune complex-mediated arthritis.

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Grevers LC, van Lent PL, Koenders MI, Walgreen B, Sloetjes AW, Nimmerjahn F, Sjef Verbeek J, and van den Berg WB

Arthritis and rheumatism 60(2):396-407, 2009 Feb - Who cited this? | PubMed ID: 19180490 | Fulltext

Myeloid-related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen-induced arthritis.

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van Lent PL, Grevers L, Blom AB, Sloetjes A, Mort JS, Vogl T, Nacken W, van den Berg WB, and Roth J

Annals of the rheumatic diseases 67(12):1750-8, 2008 Dec - Who cited this? | PubMed ID: 18055478 | Fulltext

Splenic suppressor of cytokine signaling 3 transgene expression affects T cell responses and prevents development of collagen-induced arthritis.

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Veenbergen S, Bennink MB, de Hooge AS, Arntz OJ, Smeets RL, van den Berg WB, and van de Loo FA

Arthritis and rheumatism 58(12):3742-52, 2008 Dec - Who cited this? | PubMed ID: 19035473 | Fulltext

Shift from toll-like receptor 2 (TLR-2) toward TLR-4 dependency in the erosive stage of chronic streptococcal cell wall arthritis coincident with TLR-4-mediated interleukin-17 production.

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Abdollahi-Roodsaz S, Joosten LA, Helsen MM, Walgreen B, van Lent PL, van den Bersselaar LA, Koenders MI, and van den Berg WB

Arthritis and rheumatism 58(12):3753-64, 2008 Dec - Who cited this? | PubMed ID: 19035506 | Fulltext

Stimulation of chondrocyte-mediated cartilage destruction by S100A8 in experimental murine arthritis.

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van Lent PL, Grevers LC, Blom AB, Arntz OJ, van de Loo FA, van der Kraan P, Abdollahi-Roodsaz S, Srikrishna G, Freeze H, Sloetjes A, Nacken W, Vogl T, Roth J, and van den Berg WB

Arthritis and rheumatism 58(12):3776-87, 2008 Dec - Who cited this? | PubMed ID: 19035520 | Fulltext

The molecular signature of oxidative metabolism and the mode of macrophage activation determine the shift from acute to chronic disease in experimental arthritis: Critical role of interleukin-12p40.

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Takahashi N, de Jager VC, Glück A, Letzkus M, Hartmann N, Staedtler F, Ribeiro-Dias F, Heuvelmans-Jacobs M, van den Berg WB, and Joosten LA

Arthritis and rheumatism 58(11):3471-84, 2008 Nov - Who cited this? | PubMed ID: 18975327 | Fulltext

Interleukin-1 drives pathogenic Th17 cells during spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice.

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Koenders MI, Devesa I, Marijnissen RJ, Abdollahi-Roodsaz S, Boots AM, Walgreen B, di Padova FE, Nicklin MJ, Joosten LA, and van den Berg WB

Arthritis and rheumatism 58(11):3461-70, 2008 Nov - Who cited this? | PubMed ID: 18975337 | Fulltext

Type I interferons might form the link between Toll-like receptor (TLR) 3/7 and TLR4 mediated synovial inflammation in rheumatoid arthritis (RA).

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Roelofs MF, Wenink MH, Brentano F, Abdollahi-Roodsaz S, Oppers-Walgreen B, Barrera P, van Riel PL, Joosten LA, Kyburz D, van den Berg WB, and Radstake TR

Annals of the rheumatic diseases, 2008 Sep 2 - Who cited this? | PubMed ID: 18765427 | Fulltext

Treatment with a CO-releasing molecule (CORM-3) reduces joint inflammation and erosion in murine collagen-induced arthritis.

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Ferrándiz ML, Maicas N, Garcia-Arnandis I, Terencio MC, Motterlini R, Devesa I, Joosten LA, van den Berg WB, and Alcaraz MJ

Annals of the rheumatic diseases 67(9):1211-7, 2008 Sep - Who cited this? | PubMed ID: 18063671 | Fulltext

IL-17 produced by Paneth cells drives TNF-induced shock.

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Takahashi N, Vanlaere I, De Rycke R, Cauwels A, Joosten LA, Lubberts E, van den Berg WB, and Libert C

The Journal of experimental medicine, 2008 Jul 28 - Who cited this? | PubMed ID: 18663129 | Fulltext

Tumor marker nucleoporin 88kDa regulates nucleocytoplasmic transport of NF-kappaB.

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Takahashi N, van Kilsdonk JW, Ostendorf B, Smeets R, Bruggeman SW, Alonso A, van de Loo F, Schneider M, van den Berg WB, and Swart GW

Biochemical and biophysical research communications, 2008 Jul 10 - Who cited this? | PubMed ID: 18621024 | Fulltext

Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis.

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Joosten LA, Heinhuis B, Abdollahi-Roodsaz S, Ferwerda G, Lebourhis L, Philpott DJ, Nahori MA, Popa C, Morre SA, van der Meer JW, Girardin SE, Netea MG, and van den Berg WB

Proceedings of the National Academy of Sciences of the United States of America 105(26):9017-22, 2008 Jul 1 - Who cited this? | PubMed ID: 18574154 | Fulltext

The human anti-interleukin-1b monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof of concept study in rheumatoid arthritis patients.

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Alten R, Gram H, Joosten LA, van den Berg WB, Sieper J, Wassenberg S, Burmester G, van Riel P, Diaz-Lorente M, Bruin GJ, Woodworth TG, Rordorf C, Batard Y, Wright AM, and Jung T

Arthritis research & therapy 10(3), 2008 Jun 5 - Who cited this? | PubMed ID: 18534016 | Fulltext

Destructive Arthritis in the Absence of Both Fc{gamma}RI and Fc{gamma}RIII.

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Boross P, van Lent PL, Martin-Ramirez J, van der Kaa J, Mulder MH, Claassens JW, van den Berg WB, Arandhara VL, and Verbeek JS

Journal of immunology (Baltimore, Md. : 1950) 180(7):5083-91, 2008 Apr 1 - Who cited this? | PubMed ID: 18354234 | Fulltext

Osteoarthritis in the context of ageing and evolution Loss of chondrocyte differentiation block during ageing.

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van der Kraan PM and van den Berg WB

Ageing research reviews 7(2):106-13, 2008 Apr - Who cited this? | PubMed ID: 18054526 | Fulltext

The Functional Variant (Asp299gly) of Toll-like Receptor 4 (TLR4) Influences TLR4-Mediated Cytokine Production in Rheumatoid Arthritis.

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Roelofs MF, Wenink MH, Toonen EJ, Coenen MJ, Joosten LA, van den Berg WB, van Riel PL, and Radstake TR

The Journal of rheumatology 35(4):558-651, 2008 Apr - Who cited this? | PubMed ID: 18381796 | Fulltext

Cytokines and joint erosion in arthritis.

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van den Berg WB

Nature clinical practice. Rheumatology 4(2):58-9, 2008 Feb - Who cited this? | PubMed ID: 18073726 | Fulltext

The orchestra of toll-like receptors and their potential role in frequently occurring rheumatic conditions.

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Roelofs MF, Abdollahi-Roodsaz S, Joosten LA, van den Berg WB, and Radstake TR

Arthritis and rheumatism 58(2):338-48, 2008 Feb - Who cited this? | PubMed ID: 18240239 | Fulltext

Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice: a comparative study using anti-TNFalpha, anti-IL-1alpha/beta and IL-1Ra.

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Joosten LA, Helsen MM, van de Loo FA, and van den Berg WB

Arthritis and rheumatism 58(2 Suppl):S110-22, 2008 Feb - Who cited this? | PubMed ID: 18240201 | Fulltext

Lessons from animal models of osteoarthritis.

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van den Berg WB

Current rheumatology reports 10(1):26, 2008 Jan - Who cited this? | PubMed ID: 18457608 | Fulltext

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis.

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Abdollahi-Roodsaz S, Joosten LA, Koenders MI, Devesa I, Roelofs MF, Radstake TR, Heuvelmans-Jacobs M, Akira S, Nicklin MJ, Ribeiro-Dias F, and van den Berg WB

The Journal of clinical investigation 118(1):205, 2008 Jan - Who cited this? | PubMed ID: 18060042 | Fulltext

T cell dependence of chronic destructive murine arthritis induced by repeated local activation of toll-like receptor-driven pathways: Crucial role of both interleukin-1beta and interleukin-17.

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Joosten LA, Abdollahi-Roodsaz S, Heuvelmans-Jacobs M, Helsen MM, van den Bersselaar LA, Oppers-Walgreen B, Koenders MI, and van den Berg WB

Arthritis and rheumatism 58(1):98-108, 2008 Jan - Who cited this? | PubMed ID: 18163514 | Fulltext

Application of a disease-regulated promoter is a safer mode of local IL-4 gene therapy for arthritis.

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Geurts J, Arntz OJ, Bennink MB, Joosten LA, van den Berg WB, and van de Loo FA

Gene therapy 14(23):1632-8, 2007 Dec - Who cited this? | PubMed ID: 17851546 | Fulltext

Resemblance of osteophytes in experimental osteoarthritis to transforming growth factor beta-induced osteophytes: Limited role of bone morphogenetic protein in early osteoarthritic osteophyte formation.

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Davidson EN, Vitters EL, van Beuningen HM, van de Loo FA, van den Berg WB, and van der Kraan PM

Arthritis and rheumatism 56(12):4065-73, 2007 Dec - Who cited this? | PubMed ID: 18050218 | Fulltext

Amplifying elements of arthritis and joint destruction.

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van den Berg WB, van Lent PL, Joosten LA, Abdollahi-Roodsaz S, and Koenders MI

Annals of the rheumatic diseases 66 Suppl 3:iii45-8, 2007 Nov - Who cited this? | PubMed ID: 17934095 | Fulltext

Bartonella quintana lipopolysaccharide is a natural antagonist of Toll-like receptor 4.

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Popa C, Abdollahi-Roodsaz S, Joosten LA, Takahashi N, Sprong T, Matera G, Liberto MC, Foca A, van Deuren M, Kullberg BJ, van den Berg WB, van der Meer JW, and Netea MG

Infection and immunity 75(10):4831-7, 2007 Oct - Who cited this? | PubMed ID: 17606598 | Fulltext

Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis.

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Abdollahi-Roodsaz S, Joosten LA, Roelofs MF, Radstake TR, Matera G, Popa C, van der Meer JW, Netea MG, and van den Berg WB

Arthritis and rheumatism 56(9):2957-67, 2007 Sep - Who cited this? | PubMed ID: 17763416 | Fulltext

TGF-beta and osteoarthritis.

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Blaney Davidson EN, van der Kraan PM, and van den Berg WB

Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 15(6):597-604, 2007 Jun - Who cited this? | PubMed ID: 17391995 | Fulltext

GM-CSF neutralisation suppresses inflammation and protects cartilage in acute streptococcal cell wall arthritis of mice.

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Plater-Zyberk C, Joosten LA, Helsen MM, Hepp J, Baeuerle PA, and van den Berg WB

Annals of the rheumatic diseases 66(4):452-7, 2007 Apr - Who cited this? | PubMed ID: 17020908 | Fulltext

Osteophytes: relevance and biology.

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van der Kraan PM and van den Berg WB

Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 15(3):237-44, 2007 Mar - Who cited this? | PubMed ID: 17204437 | Fulltext

Toll-like receptor 4 induced FcgammaR expression potentiates early onset of joint inflammation and cartilage destruction during immune complex arthritis: Toll-like receptor 4 largely regulates FcgammaR expression by interleukin 10.

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van Lent PL, Blom AB, Grevers L, Sloetjes A, and van den Berg WB

Annals of the rheumatic diseases 66(3):334-40, 2007 Mar - Who cited this? | PubMed ID: 17068066 | Fulltext

Cytokine targeting in osteoarthritis.

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Blom AB, van der Kraan PM, and van den Berg WB

Current drug targets 8(2):283-92, 2007 Feb - Who cited this? | PubMed ID: 17305506 | Fulltext

Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling.

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Blaney Davidson EN, Vitters EL, van Lent PL, van de Loo FA, van den Berg WB, and van der Kraan PM

Arthritis research & therapy 9(5):R102, 2007 - Who cited this? | PubMed ID: 17922907 | Fulltext

Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3.

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Blom AB, van Lent PL, Libregts S, Holthuysen AE, van der Kraan PM, van Rooijen N, and van den Berg WB

Arthritis and rheumatism 56(1):147-57, 2007 Jan - Who cited this? | PubMed ID: 17195217 | Fulltext

Urine antigen-induced arthritis.

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van den Berg WB, Joosten LA, and van Lent PL

Methods in molecular medicine 136:243-53, 2007 - Who cited this? | PubMed ID: 17983153 | Fulltext

The functional variant of the inhibitory Fcgamma receptor IIb (CD32B) is associated with the rate of radiologic joint damage and dendritic cell function in rheumatoid arthritis.

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Radstake TR, Franke B, Wenink MH, Nabbe KC, Coenen MJ, Welsing P, Bonvini E, Koenig S, van den Berg WB, Barrera P, and van Riel PL

Arthritis and rheumatism 54(12):3828-37, 2006 Dec - Who cited this? | PubMed ID: 17133580 | Fulltext

Fcgamma receptors directly mediate cartilage, but not bone, destruction in murine antigen-induced arthritis: uncoupling of cartilage damage from bone erosion and joint inflammation.

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van Lent PL, Grevers L, Lubberts E, de Vries TJ, Nabbe KC, Verbeek S, Oppers B, Sloetjes A, Blom AB, and van den Berg WB

Arthritis and rheumatism 54(12):3868-77, 2006 Dec - Who cited this? | PubMed ID: 17133594 | Fulltext

Expression of transforming growth factor-beta (TGFbeta) and the TGFbeta signalling molecule SMAD-2P in spontaneous and instability-induced osteoarthritis: role in cartilage degradation, chondrogenesis and osteophyte formation.

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Blaney Davidson EN, Vitters EL, van der Kraan PM, and van den Berg WB

Annals of the rheumatic diseases 65(11):1414-21, 2006 Nov - Who cited this? | PubMed ID: 16439443 | Fulltext

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