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Papers authored by Umehara T

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Increased inhibitory ability of conjugated RNA aptamers against the HCV IRES.

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Kikuchi K, Umehara T, Nishikawa F, Fukuda K, Hasegawa T, and Nishikawa S

Biochemical and biophysical research communications 386(1):118-23, 2009 Aug 14 - Who cited this? | PubMed ID: 19501043 | Fulltext

ST1710-DNA complex crystal structure reveals the DNA binding mechanism of the MarR family of regulators.

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Kumarevel T, Tanaka T, Umehara T, and Yokoyama S

Nucleic acids research 37(14):4723-35, 2009 Aug - Who cited this? | PubMed ID: 19509310 | Fulltext

[Caloric test in low-tone sensorineural hearing loss].

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Kimura M, Hamamura R, Umehara T, Aoi N, Sano C, Kataoka S, and Kawauchi H

Nippon Jibiinkoka Gakkai kaiho 112(8):615-22, 2009 Aug - Who cited this? | PubMed ID: 19764544 | Fulltext

Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular basis of orthogonality.

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Nozawa K, O'Donoghue P, Gundllapalli S, Araiso Y, Ishitani R, Umehara T, Söll D, and Nureki O

Nature 457(7233):1163-7, 2009 Feb 26 - Who cited this? | PubMed ID: 19118381 | Fulltext

Experimental infection of cats with Bartonella henselae resulted in rapid clearance associated with T helper 1 immune responses.

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Kabeya H, Umehara T, Okanishi H, Tasaki I, Kamiya M, Misawa A, Mikami T, and Maruyama S

Microbes and infection / Institut Pasteur 11(6-7):716-20, 2009 - Who cited this? | PubMed ID: 19348961 | Fulltext

Entropy- and Hydrolytic-Driven Positional Switching of Macrocycle between Imine- and Hydrogen-Bonding Stations in Rotaxane-Based Molecular Shuttles.

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Umehara T, Kawai H, Fujiwara K, and Suzuki T

Journal of the American Chemical Society 130(42):13981-8, 2008 Oct 22 - Who cited this? | PubMed ID: 18817381 | Fulltext

Solution structure of the extraterminal domain of the bromodomain-containing protein BRD4.

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Lin YJ, Umehara T, Inoue M, Saito K, Kigawa T, Jang MK, Ozato K, Yokoyama S, Padmanabhan B, and Guntert P

Protein science : a publication of the Protein Society, 2008 Sep 24 - Who cited this? | PubMed ID: 18815416 | Fulltext

Misacylation of pyrrolysine tRNA in vitro and in vivo.

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Gundllapalli S, Ambrogelly A, Umehara T, Li D, Polycarpo C, and Söll D

FEBS letters, 2008 Sep 5 - Who cited this? | PubMed ID: 18775710 | Fulltext

Crystal Structures of Fission Yeast Histone Chaperone Asf1 Complexed with the Hip1 B-domain or the Cac2 C Terminus.

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Malay AD, Umehara T, Matsubara-Malay K, Padmanabhan B, and Yokoyama S

The Journal of biological chemistry 283(20):14022-31, 2008 May 16 - Who cited this? | PubMed ID: 18334479 | Fulltext

Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25A.

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Mimasu S, Sengoku T, Fukuzawa S, Umehara T, and Yokoyama S

Biochemical and biophysical research communications 366(1):15-22, 2008 Feb 1 - Who cited this? | PubMed ID: 18039463 | Fulltext

Liver target delivery of small interfering RNA to the HCV gene by lactosylated cationic liposome.

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Watanabe T, Umehara T, Yasui F, Nakagawa S, Yano J, Ohgi T, Sonoke S, Satoh K, Inoue K, Yoshiba M, and Kohara M

Journal of hepatology 47(6):744-50, 2007 Dec - Who cited this? | PubMed ID: 17822798 | Fulltext

Therapeutic application of RNA interference for hepatitis C virus.

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Watanabe T, Umehara T, and Kohara M

Advanced drug delivery reviews 59(12):1263-76, 2007 Oct 10 - Who cited this? | PubMed ID: 17822803 | Fulltext

Structural basis for the recognition between the regulatory particles Nas6 and Rpt3 of the yeast 26S proteasome.

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Nakamura Y, Umehara T, Tanaka A, Horikoshi M, Padmanabhan B, and Yokoyama S

Biochemical and biophysical research communications 359(3):503-9, 2007 Aug 3 - Who cited this? | PubMed ID: 17555716 | Fulltext

Solution structure of the zinc finger HIT domain in protein FON.

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He F, Umehara T, Tsuda K, Inoue M, Kigawa T, Matsuda T, Yabuki T, Aoki M, Seki E, Terada T, Shirouzu M, Tanaka A, Sugano S, Muto Y, and Yokoyama S

Protein science : a publication of the Protein Society 16(8):1577-87, 2007 Aug - Who cited this? | PubMed ID: 17656577 | Fulltext

Purification, crystallization and preliminary X-ray diffraction of the C-terminal bromodomain from human BRD2.

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Umehara T, Wakamori M, Tanaka A, Padmanabhan B, and Yokoyama S

Acta crystallographica. Section F, Structural biology and crystallization communications 63(Pt 7):613-5, 2007 Jul 1 - Who cited this? | PubMed ID: 17620725 | Fulltext

Crystal structure analysis of the PHD domain of the transcription co-activator Pygopus.

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Nakamura Y, Umehara T, Hamana H, Hayashizaki Y, Inoue M, Kigawa T, Shirouzu M, Terada T, Tanaka A, Padmanabhan B, and Yokoyama S

Journal of molecular biology 370(1):80, 2007 Jun 29 - Who cited this? | PubMed ID: 17499269 | Fulltext

Structural and functional differences of SWIRM domain subtypes.

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Yoneyama M, Tochio N, Umehara T, Koshiba S, Inoue M, Yabuki T, Aoki M, Seki E, Matsuda T, Watanabe S, Tomo Y, Nishimura Y, Harada T, Terada T, Shirouzu M, Hayashizaki Y,

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Journal of molecular biology 369(1):222-38, 2007 May 25 - Who cited this? | PubMed ID: 17428495 | Fulltext

Evaluation of a cyclophilin inhibitor in hepatitis C virus-infected chimeric mice in vivo.

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Inoue K, Umehara T, Ruegg UT, Yasui F, Watanabe T, Yasuda H, Dumont JM, Scalfaro P, Yoshiba M, and Kohara M

Hepatology (Baltimore, Md.) 45(4):921-8, 2007 Apr - Who cited this? | PubMed ID: 17393519 | Fulltext

Purification, crystallization and preliminary X-ray diffraction analysis of the non-ATPase subunit Nas6 in complex with the ATPase subunit Rpt3 of the 26S proteasome from Saccharomyces cerevisiae.

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Nakamura Y, Umehara T, Tanaka A, Horikoshi M, Padmanabhan B, and Yokoyama S

Acta crystallographica. Section F, Structural biology and crystallization communications 63(Pt 3):190-2, 2007 Mar 1 - Who cited this? | PubMed ID: 17329811 | Fulltext

Hsp90 inhibitors suppress HCV replication in replicon cells and humanized liver mice.

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Nakagawa S, Umehara T, Matsuda C, Kuge S, Sudoh M, and Kohara M

Biochemical and biophysical research communications 353(4):882-8, 2007 Feb 23 - Who cited this? | PubMed ID: 17196931 | Fulltext

Crystal structure of the human BRD2 bromodomain: insights into dimerization and recognition of acetylated histone H4.

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Nakamura Y, Umehara T, Nakano K, Jang MK, Shirouzu M, Morita S, Uda-Tochio H, Hamana H, Terada T, Adachi N, Matsumoto T, Tanaka A, Horikoshi M, Ozato K, Padmanabhan B, and Yokoyama S

The Journal of biological chemistry 282(6):4193-201, 2007 Feb 9 - Who cited this? | PubMed ID: 17148447 | Fulltext

Crystallization of the archaeal transcription termination factor NusA: a significant decrease in twinning under microgravity conditions.

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Tanaka H, Umehara T, Inaka K, Takahashi S, Shibata R, Bessho Y, Sato M, Sugiyama S, Fusatomi E, Terada T, Shirouzu M, Sano S, Motohara M, Kobayashi T, Tanaka T, Tanaka A,

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Acta crystallographica. Section F, Structural biology and crystallization communications 63(Pt 2):69-73, 2007 Feb 1 - Who cited this? | PubMed ID: 17277442 | Fulltext

Structure of the oncoprotein gankyrin in complex with S6 ATPase of the 26S proteasome.

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Nakamura Y, Nakano K, Umehara T, Kimura M, Hayashizaki Y, Tanaka A, Horikoshi M, Padmanabhan B, and Yokoyama S

Structure (London, England : 1993) 15(2):179-89, 2007 Feb - Who cited this? | PubMed ID: 17292836 | Fulltext

Global analysis of functional surfaces of core histones with comprehensive point mutants.

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Matsubara K, Sano N, Umehara T, and Horikoshi M

Genes to cells : devoted to molecular & cellular mechanisms 12(1):13-33, 2007 Jan - Who cited this? | PubMed ID: 17212652 | Fulltext

Serine palmitoyltransferase inhibitor suppresses HCV replication in a mouse model.

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Umehara T, Sudoh M, Yasui F, Matsuda C, Hayashi Y, Chayama K, and Kohara M

Biochemical and biophysical research communications 346(1):67-73, 2006 Jul 21 - Who cited this? | PubMed ID: 16750511 | Fulltext

Dynamic covalently bonded rotaxanes cross-linked by imine bonds between the axle and ring: inverse temperature dependence of subunit mobility.

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Kawai H, Umehara T, Fujiwara K, Tsuji T, and Suzuki T

Angewandte Chemie (International ed. in English) 45(26):4281-6, 2006 Jun 26 - Who cited this? | PubMed ID: 16739149 | Fulltext

[Study of spatial resolution in three-dimensional rotational angiography].

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Enoki T, Nasada T, Matsumoto K, and Umehara T

Nippon Hoshasen Gijutsu Gakkai zasshi 62(3):434-41, 2006 Mar 20 - Who cited this? | PubMed ID: 16604049 | Fulltext

Solution structure of the SWIRM domain of human histone demethylase LSD1.

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Tochio N, Umehara T, Koshiba S, Inoue M, Yabuki T, Aoki M, Seki E, Watanabe S, Tomo Y, Hanada M, Ikari M, Sato M, Terada T, Nagase T, Ohara O, Shirouzu M,

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Structure (London, England : 1993) 14(3):457, 2006 Mar - Who cited this? | PubMed ID: 16531230 | Fulltext

Structural Similarity between Histone Chaperone Cia1p/Asf1p and DNA-Binding Protein NF-{kappa}B.

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Padmanabhan B, Kataoka K, Umehara T, Adachi N, Yokoyama S, and Horikoshi M

Journal of biochemistry 138(6):821-9, 2005 Dec - Who cited this? | PubMed ID: 16428312 | Fulltext

Purification, crystallization and preliminary X-ray diffraction analysis of the histone chaperone cia1 from fission yeast.

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Umehara T, Otta Y, Tsuganezawa K, Matsumoto T, Tanaka A, Horikoshi M, Padmanabhan B, and Yokoyama S

Acta crystallographica. Section F, Structural biology and crystallization communications 61(Pt 11):971-3, 2005 Nov 1 - Who cited this? | PubMed ID: 16511210 | Fulltext

Rational design of dual-functional aptamers that inhibit the protease and helicase activities of HCV NS3.

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Umehara T, Fukuda K, Nishikawa F, Kohara M, Hasegawa T, and Nishikawa S

Journal of biochemistry 137(3):339-47, 2005 Mar - Who cited this? | PubMed ID: 15809335 | Fulltext

A hepatitis C virus (HCV) internal ribosome entry site (IRES) domain III-IV-targeted aptamer inhibits translation by binding to an apical loop of domain IIId.

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Kikuchi K, Umehara T, Fukuda K, Kuno A, Hasegawa T, and Nishikawa S

Nucleic acids research 33(2):683-92, 2005 - Who cited this? | PubMed ID: 15681618 | Fulltext

An RNA ligand inhibits hepatitis C virus NS3 protease and helicase activities.

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Fukuda K, Umehara T, Sekiya S, Kunio K, Hasegawa T, and Nishikawa S

Biochemical and biophysical research communications 325(3):670-5, 2004 Dec 17 - Who cited this? | PubMed ID: 15541341 | Fulltext

The management of possible fishbone ingestion.

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Akazawa Y, Watanabe S, Nobukiyo S, Iwatake H, Seki Y, Umehara T, Tsutsumi K, and Koizuka I

Auris, nasus, larynx 31(4):413-6, 2004 Dec - Who cited this? | PubMed ID: 15571916 | Fulltext

Abnormalities of the electrogastrogram in globus pharyngeus.

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Nishino H, Ohashi T, Umehara T, Kenmochi M, Okada T, and Koizuka I

Acta oto-laryngologica. Supplementum(553):117-21, 2004 Aug - Who cited this? | PubMed ID: 15277050 | Fulltext

[Clinical effect of bipolar radiofrequency thermotherapy on allergic rhinitis].

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Oyake D, Ochi K, Takatsu M, Shintani T, Umehara T, and Koizuka I

Nippon Jibiinkoka Gakkai kaiho 107(7):695-701, 2004 Jul - Who cited this? | PubMed ID: 15346897 | Fulltext

Determination of tryptophan tRNA recognition sites for tryptophanyl-tRNA synthetase from hyperthermophilic archaeon, Aeropyrum pernix K1.

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Tsuchiya W, Umehara T, Kuno A, and Hasegawa T

Nucleic acids symposium series (2004)(48):185-6, 2004 - Who cited this? | PubMed ID: 17150540 | Fulltext

Designing and analysis of a potent bi-functional aptamers that inhibit protease and helicase activities of HCV NS3.

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Umehara T, Fukuda K, Nishikawa F, Sekiya S, Kohara M, Hasegawa T, and Nishikawa S

Nucleic acids symposium series (2004)(48):195-6, 2004 - Who cited this? | PubMed ID: 17150545 | Fulltext

Genome-wide expression analysis of mouse liver reveals CLOCK-regulated circadian output genes.

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Oishi K, Miyazaki K, Kadota K, Kikuno R, Nagase T, Atsumi G, Ohkura N, Azama T, Mesaki M, Yukimasa S, Kobayashi H, Iitaka C, Umehara T, Horikoshi M, Kudo T, Shimizu Y,

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The Journal of biological chemistry 278(42):41519-27, 2003 Oct 17 - Who cited this? | PubMed ID: 12865428 | Fulltext

Transcription initiation factor IID-interactive histone chaperone CIA-II implicated in mammalian spermatogenesis.

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Umehara T and Horikoshi M

The Journal of biological chemistry 278(37):35660-7, 2003 Sep 12 - Who cited this? | PubMed ID: 12842904 | Fulltext

[New theory on gene regulation: mechanism of formation of chromosome functional and boundary regions].

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Horikoshi M, Yamamoto T, Umehara T, Suzuki T, Adachi N, and Kimura A

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 48(3):205-22, 2003 Mar - Who cited this? | PubMed ID: 12652741 | Fulltext

RNA aptamers targeted to domain II of hepatitis C virus IRES that bind to its apical loop region.

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Kikuchi K, Umehara T, Fukuda K, Hwang J, Kuno A, Hasegawa T, and Nishikawa S

Journal of biochemistry 133(3):263-70, 2003 Mar - Who cited this? | PubMed ID: 12761160 | Fulltext

Structure-inhibition analysis of RNA aptamers that bind to HCV IRES.

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Kikuchi K, Umehara T, Fukuda K, Hwang J, Kuno A, Hasegawa T, and Nishikawa S

Nucleic acids research. Supplement (2001)(3):291-2, 2003 - Who cited this? | PubMed ID: 14510495 | Fulltext

Chromosomal gradient of histone acetylation established by Sas2p and Sir2p functions as a shield against gene silencing.

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Kimura A, Umehara T, and Horikoshi M

Nature genetics 32(3):370-7, 2002 Nov - Who cited this? | PubMed ID: 12410229 | Fulltext

[A design of the measuring chart for magnifying-power compensation in brain angiography].

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Matsumoto K, Sakamoto K, Umehara T, Maeda K, and Itoh H

Nippon Hoshasen Gijutsu Gakkai zasshi 58(3):413-9, 2002 Mar - Who cited this? | PubMed ID: 12522350 | Fulltext

Polyanionic stretch-deleted histone chaperone cia1/Asf1p is functional both in vivo and in vitro.

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Umehara T, Chimura T, Ichikawa N, and Horikoshi M

Genes to cells : devoted to molecular & cellular mechanisms 7(1):59-73, 2002 Jan - Who cited this? | PubMed ID: 11856374 | Fulltext

Molecular recognition of threonine tRNA by threonyl-tRNA synthetase from an extreme thermophilic archaeon, Aeropyrum pernix K1.

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Nagaoka Y, Yokozawa J, Umehara T, Iwaki J, Okamoto K, Kawarabayasi Y, Koyama Y, Sako Y, Wakagi T, Kuno A, and Hasegawa T

Nucleic acids research. Supplement (2001)(2):81-2, 2002 - Who cited this? | PubMed ID: 12903115 | Fulltext

Differences in tyrosine tRNA identity between Escherichia coli and archaeon, Aeropyrum pernix K1.

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Iwaki J, Asahara H, Nagaoka Y, Yokozawa J, Umehara T, Kawarabayasi Y, Koyama Y, Sako Y, Kuno A, and Hasegawa T

Nucleic acids research. Supplement (2001)(2):225-6, 2002 - Who cited this? | PubMed ID: 12903187 | Fulltext

In vitro selection of RNA aptamers that bind to domain II of HCV IRES.

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Kikuchi K, Fukuda K, Umehara T, Hwang J, Kuno A, Hasegawa T, and Nishikawa S

Nucleic acids research. Supplement (2001)(2):267-8, 2002 - Who cited this? | PubMed ID: 12903207 | Fulltext

Cell death with predominant apoptotic features in Saccharomyces cerevisiae mediated by deletion of the histone chaperone ASF1/CIA1.

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Yamaki M, Umehara T, Chimura T, and Horikoshi M

Genes to cells : devoted to molecular & cellular mechanisms 6(12):1043-54, 2001 Dec - Who cited this? | PubMed ID: 11737265 | Fulltext

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