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Papers authored by Ulevitch RJ

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Modulation of Gene Expression Via Disruption of NF-{kappa}B Signaling by a Bacterial Small Molecule.

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Kravchenko VV, Kaufmann GF, Mathison JC, Scott DA, Katz AZ, Grauer DC, Lehmann M, Meijler MM, Janda KD, and Ulevitch RJ

Science (New York, N.Y.), 2008 Jun 19 - Who cited this? | PubMed ID: 18566250 | Fulltext

The quorum quenching antibody RS2-1G9 protects macrophages from the cytotoxic effects of the Pseudomonas aeruginosa quorum sensing signalling molecule N-3-oxo-dodecanoyl-homoserine lactone.

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Kaufmann GF, Park J, Mee JM, Ulevitch RJ, and Janda KD

Molecular immunology 45(9):2710-4, 2008 May - Who cited this? | PubMed ID: 18304641 | Fulltext

Infection control by antibody disruption of bacterial quorum sensing signaling.

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Park J, Jagasia R, Kaufmann GF, Mathison JC, Ruiz DI, Moss JA, Meijler MM, Ulevitch RJ, and Janda KD

Chemistry & biology 14(10):1119-27, 2007 Oct - Who cited this? | PubMed ID: 17961824 | Fulltext

MDP-induced interleukin-1beta processing requires Nod2 and CIAS1/NALP3.

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Pan Q, Mathison J, Fearns C, Kravchenko VV, Da Silva Correia J, Hoffman HM, Kobayashi KS, Bertin J, Grant EP, Coyle AJ, Sutterwala FS, Ogura Y, Flavell RA, and Ulevitch RJ

Journal of leukocyte biology 82(1):177-83, 2007 Jul - Who cited this? | PubMed ID: 17403772 | Fulltext

The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis.

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da Silva Correia J, Miranda Y, Leonard N, and Ulevitch RJ

The Journal of biological chemistry 282(17):12557-65, 2007 Apr 27 - Who cited this? | PubMed ID: 17337451 | Fulltext

Regulation of Nod1-mediated signaling pathways.

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da Silva Correia J, Miranda Y, Leonard N, Hsu J, and Ulevitch RJ

Cell death and differentiation 14(4):830-9, 2007 Apr - Who cited this? | PubMed ID: 17186025 | Fulltext

Cleavage of p65/RelA of the NF-kappaB pathway by Chlamydia.

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Lad SP, Li J, da Silva Correia J, Pan Q, Gadwal S, Ulevitch RJ, and Li E

Proceedings of the National Academy of Sciences of the United States of America 104(8):2933-8, 2007 Feb 20 - Who cited this? | PubMed ID: 17301240 | Fulltext

N-(3-oxo-acyl)homoserine lactones signal cell activation through a mechanism distinct from the canonical pathogen-associated molecular pattern recognition receptor pathways.

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Kravchenko VV, Kaufmann GF, Mathison JC, Scott DA, Katz AZ, Wood MR, Brogan AP, Lehmann M, Mee JM, Iwata K, Pan Q, Fearns C, Knaus UG, Meijler MM, Janda KD, and Ulevitch RJ

The Journal of biological chemistry 281(39):28822-30, 2006 Sep 29 - Who cited this? | PubMed ID: 16893899 | Fulltext

Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4.

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Raetz CR, Garrett TA, Reynolds CM, Shaw WA, Moore JD, Smith DC, Ribeiro AA, Murphy RC, Ulevitch RJ, Fearns C, Reichart D, Glass CK, Benner C, Subramaniam S, Harkewicz R, Bowers-Gentry RC,

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Journal of lipid research 47(5):1097, 2006 May - Who cited this? | PubMed ID: 16479018 | Fulltext

Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice.

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Saleh M, Mathison JC, Wolinski MK, Bensinger SJ, Fitzgerald P, Droin N, Ulevitch RJ, Green DR, and Nicholson DW

Nature 440(7087):1064-8, 2006 Apr 20 - Who cited this? | PubMed ID: 16625199 | Fulltext

NF-kappa B-inducing kinase regulates selected gene expression in the Nod2 signaling pathway.

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Pan Q, Kravchenko V, Katz A, Huang S, Ii M, Mathison JC, Kobayashi K, Flavell RA, Schreiber RD, Goeddel D, and Ulevitch RJ

Infection and immunity 74(4):2121, 2006 Apr - Who cited this? | PubMed ID: 16552041 | Fulltext

Nod1-dependent control of tumor growth.

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da Silva Correia J, Miranda Y, Austin-Brown N, Hsu J, Mathison J, Xiang R, Zhou H, Li Q, Han J, and Ulevitch RJ

Proceedings of the National Academy of Sciences of the United States of America 103(6):1840-5, 2006 Feb 7 - Who cited this? | PubMed ID: 16446438 | Fulltext

TLR2 is required for the altered transcription of p75NGF receptors in gram positive infection.

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Wirz SA, Tobias PS, Ulevitch RJ, Aribibe L, and Bartfai T

Neurochemical research 31(2):297-301, 2006 Feb - Who cited this? | PubMed ID: 16518575 | Fulltext

Limiting inflammatory responses during activation of innate immunity.

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Han J and Ulevitch RJ

Nature immunology 6(12):1198-205, 2005 Dec - Who cited this? | PubMed ID: 16369559 | Fulltext

A synthetic TLR4 antagonist has anti-inflammatory effects in two murine models of inflammatory bowel disease.

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Fort MM, Mozaffarian A, Stöver AG, Correia Jda S, Johnson DA, Crane RT, Ulevitch RJ, Persing DH, Bielefeldt-Ohmann H, Probst P, Jeffery E, Fling SP, and Hershberg RM

Journal of immunology (Baltimore, Md. : 1950) 174(10):6416-23, 2005 May 15 - Who cited this? | PubMed ID: 15879143 | Fulltext

Innate immune responses during infection.

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Ulevitch RJ, Mathison JC, and da Silva Correia J

Vaccine 22 Suppl 1:S25-30, 2004 Dec 6 - Who cited this? | PubMed ID: 15576198 | Fulltext

Therapeutics targeting the innate immune system.

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Ulevitch RJ

Nature reviews. Immunology 4(7):512, 2004 Jul - Who cited this? | PubMed ID: 15229470 | Fulltext

Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors.

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Chuang TH and Ulevitch RJ

Nature immunology 5(5):495-502, 2004 May - Who cited this? | PubMed ID: 15107846 | Fulltext

Targeted deletion of BMK1/ERK5 in adult mice perturbs vascular integrity and leads to endothelial failure.

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Hayashi M, Kim SW, Imanaka-Yoshida K, Yoshida T, Abel ED, Eliceiri B, Yang Y, Ulevitch RJ, and Lee JD

The Journal of clinical investigation 113(8):1138-48, 2004 Apr - Who cited this? | PubMed ID: 15085193 | Fulltext

Structure-activity relationship of synthetic toll-like receptor 4 agonists.

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Stöver AG, Da Silva Correia J, Evans JT, Cluff CW, Elliott MW, Jeffery EW, Johnson DA, Lacy MJ, Baldridge JR, Probst P, Ulevitch RJ, Persing DH, and Hershberg RM

The Journal of biological chemistry 279(6):4440, 2004 Feb 6 - Who cited this? | PubMed ID: 14570885 | Fulltext

MKK3 mitogen-activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury.

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Otterbein LE, Otterbein SL, Ifedigbo E, Liu F, Morse DE, Fearns C, Ulevitch RJ, Knickelbein R, Flavell RA, and Choi AM

The American journal of pathology 163(6):2555-63, 2003 Dec - Who cited this? | PubMed ID: 14633627 | Fulltext

How we detect microbes and respond to them: the Toll-like receptors and their transducers.

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Beutler B, Hoebe K, Du X, and Ulevitch RJ

Journal of leukocyte biology 74(4):479-85, 2003 Oct - Who cited this? | PubMed ID: 12960260 | Fulltext

IKKi/IKKepsilon plays a key role in integrating signals induced by pro-inflammatory stimuli.

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Kravchenko VV, Mathison JC, Schwamborn K, Mercurio F, and Ulevitch RJ

The Journal of biological chemistry 278(29):26612-9, 2003 Jul 18 - Who cited this? | PubMed ID: 12736252 | Fulltext

Regulation of receptor-dependent activation of the innate immune response.

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Ulevitch RJ

The Journal of infectious diseases 187 Suppl 2:S351-5, 2003 Jun 15 - Who cited this? | PubMed ID: 12792851 | Fulltext

ILPIP, a novel anti-apoptotic protein that enhances XIAP-mediated activation of JNK1 and protection against apoptosis.

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Sanna MG, da Silva Correia J, Luo Y, Chuang B, Paulson LM, Nguyen B, Deveraux QL, and Ulevitch RJ

The Journal of biological chemistry 277(34):30454-62, 2002 Aug 23 - Who cited this? | PubMed ID: 12048196 | Fulltext

Two msbB genes encoding maximal acylation of lipid A are required for invasive Shigella flexneri to mediate inflammatory rupture and destruction of the intestinal epithelium.

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d'Hauteville H, Khan S, Maskell DJ, Kussak A, Weintraub A, Mathison J, Ulevitch RJ, Wuscher N, Parsot C, and Sansonetti PJ

Journal of immunology (Baltimore, Md. : 1950) 168(10):5240, 2002 May 15 - Who cited this? | PubMed ID: 11994481 | Fulltext

IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition.

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Sanna MG, da Silva Correia J, Ducrey O, Lee J, Nomoto K, Schrantz N, Deveraux QL, and Ulevitch RJ

Molecular and cellular biology 22(6):1754-66, 2002 Mar - Who cited this? | PubMed ID: 11865055 | Fulltext

Toll-like receptor 9 mediates CpG-DNA signaling.

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Chuang TH, Lee J, Kline L, Mathison JC, and Ulevitch RJ

Journal of leukocyte biology 71(3):538-44, 2002 Mar - Who cited this? | PubMed ID: 11867692 | Fulltext

MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha.

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Ge B, Gram H, Di Padova F, Huang B, New L, Ulevitch RJ, Luo Y, and Han J

Science (New York, N.Y.) 295(5558):1291-4, 2002 Feb 15 - Who cited this? | PubMed ID: 11847341 | Fulltext

MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptor.

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da Silva Correia J and Ulevitch RJ

The Journal of biological chemistry 277(3):1845-54, 2002 Jan 18 - Who cited this? | PubMed ID: 11706042 | Fulltext

New therapeutic targets revealed through investigations of innate immunity.

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Ulevitch RJ

Critical care medicine 29(7 Suppl):S8-12, 2001 Jul - Who cited this? | PubMed ID: 11445726 | Fulltext

Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2.

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da Silva Correia J, Soldau K, Christen U, Tobias PS, and Ulevitch RJ

The Journal of biological chemistry 276(24):21129-35, 2001 Jun 15 - Who cited this? | PubMed ID: 11274165 | Fulltext

Gene induction by coagulation factor Xa is mediated by activation of protease-activated receptor 1.

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Riewald M, Kravchenko VV, Petrovan RJ, O'Brien PJ, Brass LF, Ulevitch RJ, and Ruf W

Blood 97(10):3109-16, 2001 May 15 - Who cited this? | PubMed ID: 11342437 | Fulltext

Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism.

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Werts C, Tapping RI, Mathison JC, Chuang TH, Kravchenko V, Saint Girons I, Haake DA, Godowski PJ, Hayashi F, Ozinsky A, Underhill DM, Kirschning CJ, Wagner H, Aderem A, Tobias PS, and Ulevitch RJ

Nature immunology 2(4):346-52, 2001 Apr - Who cited this? | PubMed ID: 11276206 | Fulltext

Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells.

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Chuang T and Ulevitch RJ

Biochimica et biophysica acta 1518(1-2):157-61, 2001 Mar 19 - Who cited this? | PubMed ID: 11267672 | Fulltext

TAK1 regulates multiple protein kinase cascades activated by bacterial lipopolysaccharide.

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Lee J, Mira-Arbibe L, and Ulevitch RJ

Journal of leukocyte biology 68(6):909-15, 2000 Dec - Who cited this? | PubMed ID: 11129660 | Fulltext

Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway.

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Arbibe L, Mira JP, Teusch N, Kline L, Guha M, Mackman N, Godowski PJ, Ulevitch RJ, and Knaus UG

Nature immunology 1(6):533-40, 2000 Dec - Who cited this? | PubMed ID: 11101877 | Fulltext

Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9.

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Chuang TH and Ulevitch RJ

European cytokine network 11(3):372-8, 2000 Sep - Who cited this? | PubMed ID: 11022120 | Fulltext

Toll-like receptors in the induction of the innate immune response.

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Aderem A and Ulevitch RJ

Nature 406(6797):782-7, 2000 Aug 17 - Who cited this? | PubMed ID: 10963608 | Fulltext

Coordinate activation of endogenous p38alpha, beta, gamma, and delta by inflammatory stimuli.

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Fearns C, Kline L, Gram H, Di Padova F, Zurini M, Han J, and Ulevitch RJ

Journal of leukocyte biology 67(5):705-11, 2000 May - Who cited this? | PubMed ID: 10811012 | Fulltext

Blockade of CD14 increases Shigella-mediated invasion and tissue destruction.

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Wennerås C, Ave P, Huerre M, Arondel J, Ulevitch RJ, Mathison JC, and Sansonetti P

Journal of immunology (Baltimore, Md. : 1950) 164(6):3214-21, 2000 Mar 15 - Who cited this? | PubMed ID: 10706713 | Fulltext

Molecular mechanisms of innate immunity.

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Ulevitch RJ

Immunologic research 21(2-3):49-54, 2000 - Who cited this? | PubMed ID: 10852101 | Fulltext

Toll gates for pathogen selection.

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Ulevitch RJ

Nature 401(6755):755-6, 1999 Oct 21 - Who cited this? | PubMed ID: 10548095 | Fulltext

Emerging targets for anti-inflammatory therapy.

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Han J and Ulevitch RJ

Nature cell biology 1(2):E39-40, 1999 Jun - Who cited this? | PubMed ID: 10559893 | Fulltext

Lipopolysaccharide induction of tissue factor expression in rabbits.

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Erlich J, Fearns C, Mathison J, Ulevitch RJ, and Mackman N

Infection and immunity 67(5):2540-6, 1999 May - Who cited this? | PubMed ID: 10225918 | Fulltext

Endotoxin opens the Tollgates to innate immunity.

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Ulevitch RJ

Nature medicine 5(2):144-5, 1999 Feb - Who cited this? | PubMed ID: 9930855 | Fulltext

Recognition of gram-negative bacteria and endotoxin by the innate immune system.

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Ulevitch RJ and Tobias PS

Current opinion in immunology 11(1):19-22, 1999 Feb - Who cited this? | PubMed ID: 10047547 | Fulltext

[The signal transduction of cell activation by LPS: the studies from CD14 to p38 MAPK].

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Jiang Y and Ulevitch RJ

Sheng li ke xue jin zhan [Progress in physiology] 30(1):29-34, 1999 Jan - Who cited this? | PubMed ID: 12532845 | Fulltext

Regulation of the MEF2 family of transcription factors by p38.

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Zhao M, New L, Kravchenko VV, Kato Y, Gram H, di Padova F, Olson EN, Ulevitch RJ, and Han J

Molecular and cellular biology 19(1):21-30, 1999 Jan - Who cited this? | PubMed ID: 9858528 | Fulltext

Anti-CD14 mAb treatment provides therapeutic benefit after in vivo exposure to endotoxin.

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Schimke J, Mathison J, Morgiewicz J, and Ulevitch RJ

Proceedings of the National Academy of Sciences of the United States of America 95(23):13875-80, 1998 Nov 10 - Who cited this? | PubMed ID: 9811894 | Fulltext

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