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Papers authored by Tino JA

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Enhanced gastrointestinal motility with orally active ghrelin receptor agonists.

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Charoenthongtrakul S, Giuliana D, Longo KA, Govek EK, Nolan A, Gagne S, Morgan K, Hixon J, Flynn N, Murphy BJ, Hernández AS, Li J, Tino JA, Gordon DA, Distefano PS, and Geddes BJ

The Journal of pharmacology and experimental therapeutics 329(3):1178-86, 2009 Jun - Who cited this? | PubMed ID: 19252061 | Fulltext

Discovery and optimization of (R)-prolinol-derived agonists of the Growth Hormone Secretagogue receptor (GHSR).

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Zhai W, Flynn N, Longhi DA, Tino JA, Murphy BJ, Slusarchyk D, Gordon DA, Pendri A, Shi S, Stoffel R, Ma B, Sofia MJ, and Gerritz SW

Bioorganic & medicinal chemistry letters 18(18):5083-6, 2008 Sep 15 - Who cited this? | PubMed ID: 18722770 | Fulltext

(d)-2-tert-Butoxycarbonylamino-5,5-difluoro-5-phenyl-pentanoic acid: Synthesis and incorporation into the growth hormone secretagogues.

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Li J, Chen SY, Murphy BJ, Flynn N, Seethala R, Slusarchyk D, Yan M, Sleph P, Zhang H, Humphreys WG, Ewing WR, Robl JA, Gordon D, and Tino JA

Bioorganic & medicinal chemistry letters 18(14):4072-4, 2008 Jul 15 - Who cited this? | PubMed ID: 18554903 | Fulltext

Tetrazole based amides as growth hormone secretagogues.

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Li JJ, Wang H, Li J, Qu F, Swartz SG, Hernández AS, Biller SA, Robl JA, Tino JA, Slusarchyk D, Seethala R, Sleph P, Yan M, Grover G, Flynn N, Murphy BJ,

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Bioorganic & medicinal chemistry letters 18(8):2536-9, 2008 Apr 15 - Who cited this? | PubMed ID: 18378446 | Fulltext

Optimization of 1H-tetrazole-1-alkanenitriles as potent orally bioavailable growth hormone secretagogues.

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Hernández AS, Swartz SG, Slusarchyk D, Yan M, Seethala RK, Sleph P, Grover G, Dickinson K, Giupponi L, Harper TW, Humphreys WG, Longhi DA, Flynn N, Murphy BJ, Gordon DA, Biller SA,

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Bioorganic & medicinal chemistry letters 18(6):2067-72, 2008 Mar 15 - Who cited this? | PubMed ID: 18282707 | Fulltext

Design and synthesis of tetrazole-based growth hormone secretagogue: the SAR studies of the O-benzyl serine side chain.

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Li J, Chen SY, Tao S, Wang H, Li JJ, Swartz S, Musial C, Hernandez AA, Flynn N, Murphy BJ, Beehler B, Dickinson KE, Giupponi L, Grover G, Seethala R, Sleph P,

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Bioorganic & medicinal chemistry letters 18(6):1825-9, 2008 Mar 15 - Who cited this? | PubMed ID: 18295486 | Fulltext

Discovery of a Tetrazole-Based Growth Hormone Secretagogue: 4-(Hydroxybutyl)carbamic Acid 2-{5-[1-(2-Amino-2-methylpropionylamino)-2- benzyloxyethyl]tetrazol-1-yl}ethyl Ester (BMS-317180).

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Li J, Chen SY, Li JJ, Wang H, Hernandez AS, Tao S, Musial CM, Qu F, Swartz S, Chao ST, Flynn N, Murphy BJ, Slusarchyk DA, Seethala R, Yan M, Sleph P,

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Journal of medicinal chemistry 50(24):5890-3, 2007 Nov 29 - Who cited this? | PubMed ID: 17973363 | Fulltext

Discovery, synthesis, and structure-activity studies of tetrazole based growth hormone secretagogues.

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Hernández AS, Cheng PT, Musial CM, Swartz SG, George RJ, Grover G, Slusarchyk D, Seethala RK, Smith M, Dickinson K, Giupponi L, Longhi DA, Flynn N, Murphy BJ, Gordon DA, Biller SA,

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Bioorganic & medicinal chemistry letters 17(21):5928-33, 2007 Nov 1 - Who cited this? | PubMed ID: 17869100 | Fulltext

2-hydroxy-N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors.

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Li JJ, Wang H, Tino JA, Robl JA, Herpin TF, Lawrence RM, Biller S, Jamil H, Ponticiello R, Chen L, Chu CH, Flynn N, Cheng D, Zhao R, Chen B, Schnur D,

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Bioorganic & medicinal chemistry letters 17(11):3208-11, 2007 Jun 1 - Who cited this? | PubMed ID: 17383874 | Fulltext

Tetrahydroisoquinoline 1-carboxamides as growth hormone secretagogues.

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Li JJ, Wang H, Qu F, Musial C, Tino JA, Robl JA, Slusarchyk D, Golla R, Seethala R, Dickinson K, Giupponi L, Grover G, Sleph P, Flynn N, Murphy BJ, Gordon D,

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Bioorganic & medicinal chemistry letters 15(7):1799-802, 2005 Apr 1 - Who cited this? | PubMed ID: 15780609 | Fulltext

Discovery of a potent and novel motilin agonist.

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Li JJ, Chao HG, Wang H, Tino JA, Lawrence RM, Ewing WR, Ma Z, Yan M, Slusarchyk D, Seethala R, Sun H, Li D, Burford NT, Stoffel RH, Salyan ME, Li CY,

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Journal of medicinal chemistry 47(7):1704-8, 2004 Mar 25 - Who cited this? | PubMed ID: 15027861 | Fulltext

An MTP inhibitor that normalizes atherogenic lipoprotein levels in WHHL rabbits.

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Wetterau JR, Gregg RE, Harrity TW, Arbeeny C, Cap M, Connolly F, Chu CH, George RJ, Gordon DA, Jamil H, Jolibois KG, Kunselman LK, Lan SJ, Maccagnan TJ, Ricci B, Yan M,

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Science (New York, N.Y.) 282(5389):751-4, 1998 Oct 23 - Who cited this? | PubMed ID: 9784135 | Fulltext

Aminodiol HIV protease inhibitors. Synthesis and structure-activity relationships of P1/P1' compounds: correlation between lipophilicity and cytotoxicity.

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Chen P, Cheng PT, Alam M, Beyer BD, Bisacchi GS, Dejneka T, Evans AJ, Greytok JA, Hermsmeier MA, Humphreys WG, Jacobs GA, Kocy O, Lin PF, Lis KA, Marella MA, Ryono DE,

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Journal of medicinal chemistry 39(10):1991-2007, 1996 May 10 - Who cited this? | PubMed ID: 8642558 | Fulltext

Antiviral properties of aminodiol inhibitors against human immunodeficiency virus and protease.

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Bechtold CM, Patick AK, Alam M, Greytok J, Tino JA, Chen P, Gordon E, Ahmad S, Barrish JC, and Zahler R

Antimicrobial agents and chemotherapy 39(2):374-9, 1995 Feb - Who cited this? | PubMed ID: 7726501 | Fulltext

Synthesis and antiviral activity of novel isonucleoside analogs.

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Tino JA, Clark JM, Field AK, Jacobs GA, Lis KA, Michalik TL, McGeever-Rubin B, Slusarchyk WA, Spergel SH, and Sundeen JE

Journal of medicinal chemistry 36(9):1221-9, 1993 Apr 30 - Who cited this? | PubMed ID: 8387600 | Fulltext

Synthesis and antiviral activity of 1-cyclobutyl-5-(2-bromovinyl)uracil nucleoside analogues and related compounds.

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Slusarchyk WA, Bisacchi GS, Field AK, Hockstein DR, Jacobs GA, McGeever-Rubin B, Tino JA, Tuomari AV, Yamanaka GA, and Young MG

Journal of medicinal chemistry 35(10):1799-806, 1992 May 15 - Who cited this? | PubMed ID: 1316966 | Fulltext

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