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Papers authored by Ting JP

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NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways.

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Willingham SB, Allen IC, Bergstralh DT, Brickey WJ, Huang MT, Taxman DJ, Duncan JA, and Ting JP

Journal of immunology (Baltimore, Md. : 1950) 183(3):2008-15, 2009 Aug 1 - Who cited this? | PubMed ID: 19587006 | Fulltext

Neisseria gonorrhoeae Activates the Proteinase Cathepsin B to Mediate the Signaling Activities of the NLRP3 and ASC-Containing Inflammasome.

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Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, Bergstralh DT, Jarvis GA, Sparling PF, and Ting JP

Journal of immunology (Baltimore, Md. : 1950) 182(10):6460-9, 2009 May 15 - Who cited this? | PubMed ID: 19414800 | Fulltext

The NLRP3 inflammasome mediates in vivo innate immunity to influenza a virus through recognition of viral RNA.

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Allen IC, Scull MA, Moore CB, Holl EK, McElvania-TeKippe E, Taxman DJ, Guthrie EH, Pickles RJ, and Ting JP

Immunity 30(4):556-65, 2009 Apr - Who cited this? | PubMed ID: 19362020 | Fulltext

Blimp-1/PRDM1 Mediates Transcriptional Suppression of the NLR Gene NLRP12/Monarch-1.

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Lord CA, Savitsky D, Sitcheran R, Calame K, Wright JR, Ting JP, and Williams KL

Journal of immunology (Baltimore, Md. : 1950) 182(5):2948-58, 2009 Mar 1 - Who cited this? | PubMed ID: 19234190 | Fulltext

Critical Role of Apoptotic Speck Protein Containing a Caspase Recruitment Domain (ASC) and NLRP3 in Causing Necrosis and ASC Speck Formation Induced by Porphyromonas gingivalis in Human Cells.

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Huang MT, Taxman DJ, Holley-Guthrie EA, Moore CB, Willingham SB, Madden V, Parsons RK, Featherstone GL, Arnold RR, O'Connor BP, and Ting JP

Journal of immunology (Baltimore, Md. : 1950) 182(4):2395-404, 2009 Feb 15 - Who cited this? | PubMed ID: 19201894 | Fulltext

MAVS-mediated apoptosis and its inhibition by viral proteins.

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Lei Y, Moore CB, Liesman RM, O'Connor BP, Bergstralh DT, Chen ZJ, Pickles RJ, and Ting JP

PLoS ONE 4(5):e5466, 2009 - Who cited this? | PubMed ID: 19404494 | Fulltext

Staphylococcus aureus alpha-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells.

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Craven RR, Gao X, Allen IC, Gris D, Bubeck Wardenburg J, McElvania-Tekippe E, Ting JP, and Duncan JA

PLoS ONE 4(10):e7446, 2009 - Who cited this? | PubMed ID: 19826485 | Fulltext

MHC class II exacerbates demyelination in vivo independently of T cells.

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Hiremath MM, Chen VS, Suzuki K, Ting JP, and Matsushima GK

Journal of neuroimmunology 203(1):23-32, 2008 Oct 15 - Who cited this? | PubMed ID: 18805594 | Fulltext

Semaphorin 6D regulates the late phase of CD4+ T cell primary immune responses.

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O'Connor BP, Eun SY, Ye Z, Zozulya AL, Lich JD, Moore CB, Iocca HA, Roney KE, Holl EK, Wu QP, van Deventer HW, Fabry Z, and Ting JP

Proceedings of the National Academy of Sciences of the United States of America 105(35):13015-20, 2008 Sep 2 - Who cited this? | PubMed ID: 18728195 | Fulltext

Selective targeting of leukemic cells growth in vivo and in vitro using a gene silencing approach to diminish S-adenosylmethionine (SAMe) synthesis.

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Ramy AR, Gardner L, Mahrous E, Taxman DJ, Legros LL, Rowe S, Ting JP, Geller AM, and Kotb M

The Journal of biological chemistry, 2008 Aug 27 - Who cited this? | PubMed ID: 18753136 | Fulltext

NLRs and the dangers of pollution and aging.

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Willingham SB and Ting JP

Nature immunology 9(8):831, 2008 Aug - Who cited this? | PubMed ID: 18645588 | Fulltext

The evolving role of semaphorins and plexins in the immune system: Plexin-A1 regulation of dendritic cell function.

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O'Connor BP and Ting JP

Immunologic research, 2008 Jul 23 - Who cited this? | PubMed ID: 18649144 | Fulltext

Cutting Edge: Inflammasome Activation by Alum and Alum's Adjuvant Effect Are Mediated by NLRP3.

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Li H, Willingham SB, Ting JP, and Re F

Journal of immunology (Baltimore, Md. : 1950) 181(1):17-21, 2008 Jul 1 - Who cited this? | PubMed ID: 18566365 | Fulltext

C-C chemokine receptor 5 on pulmonary fibrocytes facilitates migration and promotes metastasis via matrix metalloproteinase 9.

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van Deventer HW, Wu QP, Bergstralh DT, Davis BK, O'Connor BP, Ting JP, and Serody JS

The American journal of pathology 173(1):253-64, 2008 Jul - Who cited this? | PubMed ID: 18535183 | Fulltext

Regulation of mitochondrial antiviral signaling pathways.

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Moore CB and Ting JP

Immunity 28(6):735, 2008 Jun - Who cited this? | PubMed ID: 18549796 | Fulltext

Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK.

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Dan HC, Cooper MJ, Cogswell PC, Duncan JA, Ting JP, and Baldwin AS

Genes & development 22(11):1490-500, 2008 Jun 1 - Who cited this? | PubMed ID: 18519641 | Fulltext

Enhancement of DNA vaccine potency through coadministration of CIITA DNA with DNA vaccines via gene gun.

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Kim D, Hoory T, Monie A, Ting JP, Hung CF, and Wu TC

Journal of immunology (Baltimore, Md. : 1950) 180(10):7019, 2008 May 15 - Who cited this? | PubMed ID: 18453624 | Fulltext

NLRs at the intersection of cell death and immunity.

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Ting JP, Willingham SB, and Bergstralh DT

Nature reviews. Immunology 8(5):372-9, 2008 May - Who cited this? | PubMed ID: 18362948 | Fulltext

The 19S proteasome ATPase Sug1 plays a critical role in regulating MHC class II transcription.

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Bhat KP, Turner JD, Myers SE, Cape AD, Ting JP, and Greer SF

Molecular immunology 45(8):2214, 2008 Apr - Who cited this? | PubMed ID: 18215421 | Fulltext

Development of an inhaled endotoxin challenge protocol for characterizing evoked cell surface phenotype and genomic responses of airway cells in allergic individuals.

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Alexis NE, Brickey WJ, Lay JC, Wang Y, Roubey RA, Ting JP, and Peden DB

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 100(3):206, 2008 Mar - Who cited this? | PubMed ID: 18426139 | Fulltext

The NLR gene family: a standard nomenclature.

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Ting JP, Lovering RC, Alnemri ES, Bertin J, Boss JM, Davis BK, Flavell RA, Girardin SE, Godzik A, Harton JA, Hoffman HM, Hugot JP, Inohara N, MacKenzie A, Maltais LJ, Nunez G,

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Immunity 28(3):285, 2008 Mar - Who cited this? | PubMed ID: 18341998 | Fulltext

ATP binding by monarch-1/NLRP12 is critical for its inhibitory function.

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Ye Z, Lich JD, Moore CB, Duncan JA, Williams KL, and Ting JP

Molecular and cellular biology 28(5):1841-50, 2008 Mar - Who cited this? | PubMed ID: 18160710 | Fulltext

TNF superfamily member TWEAK exacerbates inflammation and demyelination in the cuprizone-induced model.

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Iocca HA, Plant SR, Wang Y, Runkel L, O'Connor BP, Lundsmith ET, Hahm K, van Deventer HW, Burkly LC, and Ting JP

Journal of neuroimmunology 194(1-2):97, 2008 Feb - Who cited this? | PubMed ID: 18207576 | Fulltext

NLR, the nucleotide-binding domain leucine-rich repeat containing gene family.

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Ye Z and Ting JP

Current opinion in immunology 20(1):3-9, 2008 Feb - Who cited this? | PubMed ID: 18280719 | Fulltext

NLRX1 is a regulator of mitochondrial antiviral immunity.

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Moore CB, Bergstralh DT, Duncan JA, Lei Y, Morrison TE, Zimmermann AG, Accavitti-Loper MA, Madden VJ, Sun L, Ye Z, Lich JD, Heise MT, Chen Z, and Ting JP

Nature 451(7178):573-7, 2008 Jan 31 - Who cited this? | PubMed ID: 18200010 | Fulltext

Osteoblasts express NLRP3, a nucleotide-binding domain and leucine-rich repeat region containing receptor implicated in bacterially induced cell death.

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McCall SH, Sahraei M, Young AB, Worley CS, Duncan JA, Ting JP, and Marriott I

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 23(1):30-40, 2008 Jan - Who cited this? | PubMed ID: 17907925 | Fulltext

Heat shock protein 90 associates with monarch-1 and regulates its ability to promote degradation of NF-kappaB-inducing kinase.

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Arthur JC, Lich JD, Aziz RK, Kotb M, and Ting JP

Journal of immunology (Baltimore, Md. : 1950) 179(9):6291-6, 2007 Nov 1 - Who cited this? | PubMed ID: 17947705 | Fulltext

Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC.

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Willingham SB, Bergstralh DT, O'Connor W, Morrison AC, Taxman DJ, Duncan JA, Barnoy S, Venkatesan MM, Flavell RA, Deshmukh M, Hoffman HM, and Ting JP

Cell host & microbe 2(3):147-59, 2007 Sep 13 - Who cited this? | PubMed ID: 18005730 | Fulltext

Lymphotoxin beta receptor (Lt betaR): dual roles in demyelination and remyelination and successful therapeutic intervention using Lt betaR-Ig protein.

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Plant SR, Iocca HA, Wang Y, Thrash JC, O'Connor BP, Arnett HA, Fu YX, Carson MJ, and Ting JP

The Journal of neuroscience : the official journal of the Society for Neuroscience 27(28):7429, 2007 Jul 11 - Who cited this? | PubMed ID: 17626203 | Fulltext

CATERPILLER (NLR) family members as positive and negative regulators of inflammatory responses.

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Lich JD and Ting JP

Proceedings of the American Thoracic Society 4(3):263-6, 2007 Jul - Who cited this? | PubMed ID: 17607010 | Fulltext

Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models.

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Burrer R, Neuman BW, Ting JP, Stein DA, Moulton HM, Iversen PL, Kuhn P, and Buchmeier MJ

Journal of virology 81(11):5637-48, 2007 Jun - Who cited this? | PubMed ID: 17344287 | Fulltext

Mapping the landscape of the lymphocytic choriomeningitis virus stable signal peptide reveals novel functional domains.

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Saunders AA, Ting JP, Meisner J, Neuman BW, Perez M, de la Torre JC, and Buchmeier MJ

Journal of virology 81(11):5649-57, 2007 Jun - Who cited this? | PubMed ID: 17376927 | Fulltext

Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling.

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Duncan JA, Bergstralh DT, Wang Y, Willingham SB, Ye Z, Zimmermann AG, and Ting JP

Proceedings of the National Academy of Sciences of the United States of America 104(19):8041-6, 2007 May 8 - Who cited this? | PubMed ID: 17483456 | Fulltext

Monarch-1/PYPAF7 and other CATERPILLER (CLR, NOD, NLR) proteins with negative regulatory functions.

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Lich JD and Ting JP

Microbes and infection / Institut Pasteur 9(5):672-6, 2007 Apr - Who cited this? | PubMed ID: 17418609 | Fulltext

Rebuilding host-pathogen interaction from the ground up: in vitro reconstitution of the inflammasome.

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Duncan JA and Ting JP

Cell host & microbe 1(1):7-9, 2007 Mar 15 - Who cited this? | PubMed ID: 18005676 | Fulltext

HLA-A2-restricted protection against lethal lymphocytic choriomeningitis.

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Botten J, Whitton JL, Barrowman P, Sidney J, Whitmire JK, Alexander J, Ting JP, Bui HH, Sette A, and Buchmeier MJ

Journal of virology 81(5):2307-17, 2007 Mar - Who cited this? | PubMed ID: 17166907 | Fulltext

Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes.

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Lich JD, Williams KL, Moore CB, Arthur JC, Davis BK, Taxman DJ, and Ting JP

Journal of immunology (Baltimore, Md. : 1950) 178(3):1256-60, 2007 Feb 1 - Who cited this? | PubMed ID: 17237370 | Fulltext

Exacerbated pathology of viral encephalitis in mice with central nervous system-specific autoantibodies.

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Burrer R, Buchmeier MJ, Wolfe T, Ting JP, Feuer R, Iglesias A, and von Herrath MG

The American journal of pathology 170(2):557-66, 2007 Feb - Who cited this? | PubMed ID: 17255324 | Fulltext

Differential induction of type I interferon responses in myeloid dendritic cells by mosquito and mammalian-cell-derived alphaviruses.

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Shabman RS, Morrison TE, Moore C, White L, Suthar MS, Hueston L, Rulli N, Lidbury B, Ting JP, Mahalingam S, and Heise MT

Journal of virology 81(1):237-47, 2007 Jan - Who cited this? | PubMed ID: 17079324 | Fulltext

Global functional analysis of nucleophosmin in Taxol response, cancer, chromatin regulation, and ribosomal DNA transcription.

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Bergstralh DT, Conti BJ, Moore CB, Brickey WJ, Taxman DJ, and Ting JP

Experimental cell research 313(1):65-76, 2007 Jan 1 - Who cited this? | PubMed ID: 17069796 | Fulltext

Downregulation of immune signaling genes in patients with large surface burn injury.

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Moore CB, Medina MA, van Deventer HW, O'Connor BP, Cameron S, Taxman DJ, Maile R, Ting JP, and Cairns BA

Journal of burn care & research : official publication of the American Burn Association 28(6):879-87, 2007 - Who cited this? | PubMed ID: 17925653 | Fulltext

The SecA2 secretion factor of Mycobacterium tuberculosis promotes growth in macrophages and inhibits the host immune response.

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Kurtz S, McKinnon KP, Runge MS, Ting JP, and Braunstein M

Infection and immunity 74(12):6855, 2006 Dec - Who cited this? | PubMed ID: 17030572 | Fulltext

DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2.

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Clements CM, McNally RS, Conti BJ, Mak TW, and Ting JP

Proceedings of the National Academy of Sciences of the United States of America 103(41):15091-6, 2006 Oct 10 - Who cited this? | PubMed ID: 17015834 | Fulltext

Cutting edge: ASC mediates the induction of multiple cytokines by Porphyromonas gingivalis via caspase-1-dependent and -independent pathways.

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Taxman DJ, Zhang J, Champagne C, Bergstralh DT, Iocca HA, Lich JD, and Ting JP

Journal of immunology (Baltimore, Md. : 1950) 177(7):4252-6, 2006 Oct 1 - Who cited this? | PubMed ID: 16982856 | Fulltext

Cutting edge: rho activation and actin polarization are dependent on plexin-A1 in dendritic cells.

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Eun SY, O'Connor BP, Wong AW, van Deventer HW, Taxman DJ, Reed W, Li P, Blum JS, McKinnon KP, and Ting JP

Journal of immunology (Baltimore, Md. : 1950) 177(7):4271-5, 2006 Oct 1 - Who cited this? | PubMed ID: 16982860 | Fulltext

Epigenetic regulation of MHC-II and CIITA genes.

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Wright KL and Ting JP

Trends in immunology 27(9):405-12, 2006 Sep - Who cited this? | PubMed ID: 16870508 | Fulltext

Microtubule stabilizing agents: their molecular signaling consequences and the potential for enhancement by drug combination.

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Bergstralh DT and Ting JP

Cancer treatment reviews 32(3):166-79, 2006 May - Who cited this? | PubMed ID: 16527420 | Fulltext

The immunogenicity of human adipose-derived cells: temporal changes in vitro.

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McIntosh K, Zvonic S, Garrett S, Mitchell JB, Floyd ZE, Hammill L, Kloster A, Di Halvorsen Y, Ting JP, Storms RW, Goh B, Kilroy G, Wu X, and Gimble JM

Stem cells (Dayton, Ohio) 24(5):1246-53, 2006 May - Who cited this? | PubMed ID: 16410391 | Fulltext

Upregulation of the stress-associated gene p8 in mouse models of demyelination and in multiple sclerosis tissues.

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Plant SR, Wang Y, Vasseur S, Thrash JC, McMahon EJ, Bergstralh DT, Arnett HA, Miller SD, Carson MJ, Iovanna JL, and Ting JP

Glia 53(5):529-37, 2006 Apr 1 - Who cited this? | PubMed ID: 16374777 | Fulltext

Cryopyrin: in from the cold.

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Lich JD, Arthur JC, and Ting JP

Immunity 24(3):241, 2006 Mar - Who cited this? | PubMed ID: 16546091 | Fulltext

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