Please enable Javascript

Labmeeting uses lots of Javascript - basically you can't use the site without it. So please enable Javascript in your browser. If your browser does not support Javascript, we recommend Firefox.

Papers authored by Thornberry NA

Collect these papers and discover other ones on Labmeeting. Learn more.

Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes.

+ cite this

+ View Abstract

Mu J, Petrov A, Eiermann GJ, Woods J, Zhou YP, Li Z, Zycband E, Feng Y, Zhu L, Roy RS, Howard AD, Li C, Thornberry NA, and Zhang BB

European journal of pharmacology 623(1-3):148-54, 2009 Nov 25 - Who cited this? | PubMed ID: 19765579 | Fulltext

Aminopiperidine-fused imidazoles as dipeptidyl peptidase-IV inhibitors.

+ cite this

+ View Abstract

Edmondson SD, Mastracchio A, Cox JM, Eiermann GJ, He H, Lyons KA, Patel RA, Patel SB, Petrov A, Scapin G, Wu JK, Xu S, Zhu B, Thornberry NA, Roy RS, and Weber AE

Bioorganic & medicinal chemistry letters 19(15):4097-101, 2009 Aug 1 - Who cited this? | PubMed ID: 19539471 | Fulltext

Mechanism of action of inhibitors of dipeptidyl-peptidase-4 (DPP-4).

+ cite this

+ View Abstract

Thornberry NA and Gallwitz B

Best practice & research. Clinical endocrinology & metabolism 23(4):479-86, 2009 Aug - Who cited this? | PubMed ID: 19748065 | Fulltext

Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice.

+ cite this

+ View Abstract

Zhao E, Keller MP, Rabaglia ME, Oler AT, Stapleton DS, Schueler KL, Neto EC, Moon JY, Wang P, Wang IM, Lum PY, Ivanovska I, Cleary M, Greenawalt D, Tsang J, Choi YJ,

(show remaining authors)

Mammalian genome : official journal of the International Mammalian Genome Society 20(8):476-85, 2009 Aug - Who cited this? | PubMed ID: 19727952 | Fulltext

Discovery of new binding elements in DPP-4 inhibition and their applications in novel DPP-4 inhibitor design.

+ cite this

+ View Abstract

Liang GB, Qian X, Biftu T, Singh S, Gao YD, Scapin G, Patel S, Leiting B, Patel R, Wu J, Zhang X, Thornberry NA, and Weber AE

Bioorganic & medicinal chemistry letters 18(13):3706-10, 2008 Jul 1 - Who cited this? | PubMed ID: 18524582 | Fulltext

Selective Small-Molecule Agonists of G protein-coupled Receptor 40 Promote Glucose-Dependent Insulin Secretion and Reduce Blood Glucose in Mice.

+ cite this

+ View Abstract

Tan CP, Feng Y, Zhou YP, Eiermann GJ, Petrov A, Zhou C, Lin S, Salituro G, Meinke P, Mosley R, Akiyama TE, Einstein M, Kumar S, Berger JP, Mills SG, Thornberry NA,

(show remaining authors)

Diabetes, 2008 May 13 - Who cited this? | PubMed ID: 18477808 | Fulltext

Fluoroolefins as amide bond mimics in dipeptidyl peptidase IV inhibitors.

+ cite this

+ View Abstract

Edmondson SD, Wei L, Xu J, Shang J, Xu S, Pang J, Chaudhary A, Dean DC, He H, Leiting B, Lyons KA, Patel RA, Patel SB, Scapin G, Wu JK, Beconi MG,

(show remaining authors)

Bioorganic & medicinal chemistry letters 18(7):2409-13, 2008 Apr 1 - Who cited this? | PubMed ID: 18331795 | Fulltext

Identification of Glucose-Dependant Insulin Secretion Targets in Pancreatic {beta} Cells by Combining Defined-Mechanism Compound Library Screening and siRNA Gene Silencing.

+ cite this

+ View Abstract

Weizhen Wu, Jin Shang, Yue Feng, Thompson CM, Horwitz S, Thompson JR, Macintyre ED, Thornberry NA, Chapman K, Zhou YP, Howard AD, and Jing Li

Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening 13(2):128-34, 2008 Mar - Who cited this? | PubMed ID: 18216393 | Fulltext

Discovery of Potent and Selective Dipeptidyl Peptidase IV Inhibitors Derived from beta-Aminoamides Bearing Subsituted Triazolopiperazines.

+ cite this

+ View Abstract

Kim D, Kowalchick JE, Brockunier LL, Parmee ER, Eiermann GJ, Fisher MH, He H, Leiting B, Lyons K, Scapin G, Patel SB, Petrov A, Pryor KD, Roy RS, Wu JK, Zhang X,

(show remaining authors)

Journal of medicinal chemistry 51(3):589-602, 2008 Feb 14 - Who cited this? | PubMed ID: 18201067 | Fulltext

Design, synthesis, and biological evaluation of triazolopiperazine-based beta-amino amides as potent, orally active dipeptidyl peptidase IV (DPP-4) inhibitors.

+ cite this

+ View Abstract

Kowalchick JE, Leiting B, Pryor KD, Marsilio F, Wu JK, He H, Lyons KA, Eiermann GJ, Petrov A, Scapin G, Patel RA, Thornberry NA, Weber AE, and Kim D

Bioorganic & medicinal chemistry letters 17(21):5934-9, 2007 Nov 1 - Who cited this? | PubMed ID: 17827003 | Fulltext

4-arylcyclohexylalanine analogs as potent, selective, and orally active inhibitors of dipeptidyl peptidase IV.

+ cite this

+ View Abstract

Kaelin DE, Smenton AL, Eiermann GJ, He H, Leiting B, Lyons KA, Patel RA, Patel SB, Petrov A, Scapin G, Wu JK, Thornberry NA, Weber AE, and Duffy JL

Bioorganic & medicinal chemistry letters 17(21):5806-11, 2007 Nov 1 - Who cited this? | PubMed ID: 17851076 | Fulltext

Imidazopiperidine amides as dipeptidyl peptidase IV inhibitors for the treatment of diabetes.

+ cite this

+ View Abstract

Chen P, Caldwell CG, Mathvink RJ, Leiting B, Marsilio F, Patel RA, Wu JK, He H, Lyons KA, Thornberry NA, and Weber AE

Bioorganic & medicinal chemistry letters 17(21):5853-7, 2007 Nov 1 - Who cited this? | PubMed ID: 17869513 | Fulltext

Discovery of 3-aminopiperidines as potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitors.

+ cite this

+ View Abstract

Cox JM, Harper B, Mastracchio A, Leiting B, Sinha Roy R, Patel RA, Wu JK, Lyons KA, He H, Xu S, Zhu B, Thornberry NA, Weber AE, and Edmondson SD

Bioorganic & medicinal chemistry letters 17(16):4579-83, 2007 Aug 15 - Who cited this? | PubMed ID: 17562364 | Fulltext

Modeling assisted rational design of novel, potent, and selective pyrrolopyrimidine DPP-4 inhibitors.

+ cite this

+ View Abstract

Gao YD, Feng D, Sheridan RP, Scapin G, Patel SB, Wu JK, Zhang X, Sinha-Roy R, Thornberry NA, Weber AE, and Biftu T

Bioorganic & medicinal chemistry letters 17(14):3877-9, 2007 Jul 15 - Who cited this? | PubMed ID: 17502141 | Fulltext

Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin.

+ cite this

+ View Abstract

Biftu T, Scapin G, Singh S, Feng D, Becker JW, Eiermann G, He H, Lyons K, Patel S, Petrov A, Sinha-Roy R, Zhang B, Wu J, Zhang X, Doss GA, Thornberry NA,

(show remaining authors)

Bioorganic & medicinal chemistry letters 17(12):3384-7, 2007 Jun 15 - Who cited this? | PubMed ID: 17433672 | Fulltext

Triazolopiperazine-amides as dipeptidyl peptidase IV inhibitors: close analogs of JANUVIA (sitagliptin phosphate).

+ cite this

+ View Abstract

Kim D, Kowalchick JE, Edmondson SD, Mastracchio A, Xu J, Eiermann GJ, Leiting B, Wu JK, Pryor KD, Patel RA, He H, Lyons KA, Thornberry NA, and Weber AE

Bioorganic & medicinal chemistry letters 17(12):3373-7, 2007 Jun 15 - Who cited this? | PubMed ID: 17434732 | Fulltext

4-aminophenylalanine and 4-aminocyclohexylalanine derivatives as potent, selective, and orally bioavailable inhibitors of dipeptidyl peptidase IV.

+ cite this

+ View Abstract

Duffy JL, Kirk BA, Wang L, Eiermann GJ, He H, Leiting B, Lyons KA, Patel RA, Patel SB, Petrov A, Scapin G, Wu JK, Thornberry NA, and Weber AE

Bioorganic & medicinal chemistry letters 17(10):2879-85, 2007 May 15 - Who cited this? | PubMed ID: 17350841 | Fulltext

Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: focus on sitagliptin.

+ cite this

+ View Abstract

Herman GA, Stein PP, Thornberry NA, and Wagner JA

Clinical pharmacology and therapeutics 81(5):761-7, 2007 May - Who cited this? | PubMed ID: 17392725 | Fulltext

Optimization of 1,4-diazepan-2-one containing dipeptidyl peptidase IV inhibitors for the treatment of type 2 diabetes.

+ cite this

+ View Abstract

Liang GB, Qian X, Feng D, Biftu T, Eiermann G, He H, Leiting B, Lyons K, Petrov A, Sinha-Roy R, Zhang B, Wu J, Zhang X, Thornberry NA, and Weber AE

Bioorganic & medicinal chemistry letters 17(7):1903-7, 2007 Apr 1 - Who cited this? | PubMed ID: 17291750 | Fulltext

Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the bid pathway.

+ cite this

+ View Abstract

Casciola-Rosen L, Garcia-Calvo M, Bull HG, Becker JW, Hines T, Thornberry NA, and Rosen A

The Journal of biological chemistry 282(7):4545-52, 2007 Feb 16 - Who cited this? | PubMed ID: 17179148 | Fulltext

(3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one, a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.

+ cite this

+ View Abstract

Biftu T, Feng D, Qian X, Liang GB, Kieczykowski G, Eiermann G, He H, Leiting B, Lyons K, Petrov A, Sinha-Roy R, Zhang B, Scapin G, Patel S, Gao YD, Singh S,

(show remaining authors)

Bioorganic & medicinal chemistry letters 17(1):49, 2007 Jan 1 - Who cited this? | PubMed ID: 17055272 | Fulltext

Discovery of JANUVIA (Sitagliptin), a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.

+ cite this

+ View Abstract

Thornberry NA and Weber AE

Current topics in medicinal chemistry 7(6):557-68, 2007 - Who cited this? | PubMed ID: 17352677 | Fulltext

Discovery of potent, selective, and orally bioavailable oxadiazole-based dipeptidyl peptidase IV inhibitors.

+ cite this

+ View Abstract

Xu J, Wei L, Mathvink RJ, Edmondson SD, Eiermann GJ, He H, Leone JF, Leiting B, Lyons KA, Marsilio F, Patel RA, Patel SB, Petrov A, Scapin G, Wu JK, Thornberry NA,

(show remaining authors)

Bioorganic & medicinal chemistry letters 16(20):5373-7, 2006 Oct 15 - Who cited this? | PubMed ID: 16919457 | Fulltext

(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-a]-pyridin-6-ylphenyl)butanamide: a selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.

+ cite this

+ View Abstract

Edmondson SD, Mastracchio A, Mathvink RJ, He J, Harper B, Park YJ, Beconi M, Di Salvo J, Eiermann GJ, He H, Leiting B, Leone JF, Levorse DA, Lyons K, Patel RA, Patel SB,

(show remaining authors)

Journal of medicinal chemistry 49(12):3614-27, 2006 Jun 15 - Who cited this? | PubMed ID: 16759103 | Fulltext

Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic beta-cell mass and function in a rodent model of type 2 diabetes.

+ cite this

+ View Abstract

Mu J, Woods J, Zhou YP, Roy RS, Li Z, Zycband E, Feng Y, Zhu L, Li C, Howard AD, Moller DE, Thornberry NA, and Zhang BB

Diabetes 55(6):1695-704, 2006 Jun - Who cited this? | PubMed ID: 16731832 | Fulltext

Discovery of potent, selective, and orally bioavailable pyridone-based dipeptidyl peptidase-4 inhibitors.

+ cite this

+ View Abstract

Xu J, Wei L, Mathvink R, Edmondson SD, Mastracchio A, Eiermann GJ, He H, Leone JF, Leiting B, Lyons KA, Marsilio F, Patel RA, Petrov A, Wu JK, Thornberry NA, and Weber AE

Bioorganic & medicinal chemistry letters 16(5):1346-9, 2006 Mar 1 - Who cited this? | PubMed ID: 16332437 | Fulltext

Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9.

+ cite this

+ View Abstract

Lankas GR, Leiting B, Roy RS, Eiermann GJ, Beconi MG, Biftu T, Chan CC, Edmondson S, Feeney WP, He H, Ippolito DE, Kim D, Lyons KA, Ok HO, Patel RA, Petrov AN,

(show remaining authors)

Diabetes 54(10):2988-94, 2005 Oct - Who cited this? | PubMed ID: 16186403 | Fulltext

Lipophilic versus hydrogen-bonding effect in P3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitors.

+ cite this

+ View Abstract

Mellon C, Aspiotis R, Black CW, Bayly CI, Grimm EL, Giroux A, Han Y, Isabel E, McKay DJ, Nicholson DW, Rasper DM, Roy S, Tam J, Thornberry NA, Vaillancourt JP, Xanthoudakis S,

(show remaining authors)

Bioorganic & medicinal chemistry letters 15(17):3886-90, 2005 Sep 1 - Who cited this? | PubMed ID: 16023344 | Fulltext

Discovery of potent and selective orally bioavailable beta-substituted phenylalanine derived dipeptidyl peptidase IV inhibitors.

+ cite this

+ View Abstract

Edmondson SD, Mastracchio A, Duffy JL, Eiermann GJ, He H, Ita I, Leiting B, Leone JF, Lyons KA, Makarewicz AM, Patel RA, Petrov A, Wu JK, Thornberry NA, and Weber AE

Bioorganic & medicinal chemistry letters 15(12):3048-52, 2005 Jun 15 - Who cited this? | PubMed ID: 15908206 | Fulltext

The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1).

+ cite this

+ View Abstract

Garcia-Calvo M, Lisnock J, Bull HG, Hawes BE, Burnett DA, Braun MP, Crona JH, Davis HR, Dean DC, Detmers PA, Graziano MP, Hughes M, Macintyre DE, Ogawa A, O'neill KA, Iyer SP,

(show remaining authors)

Proceedings of the National Academy of Sciences of the United States of America 102(23):8132-7, 2005 Jun 7 - Who cited this? | PubMed ID: 15928087 | Fulltext

Discovery of potent and selective phenylalanine based dipeptidyl peptidase IV inhibitors.

+ cite this

+ View Abstract

Xu J, Wei L, Mathvink R, He J, Park YJ, He H, Leiting B, Lyons KA, Marsilio F, Patel RA, Wu JK, Thornberry NA, and Weber AE

Bioorganic & medicinal chemistry letters 15(10):2533-6, 2005 May 16 - Who cited this? | PubMed ID: 15863311 | Fulltext

Dipeptidyl peptidase IV inhibitors derived from beta-aminoacylpiperidines bearing a fused thiazole, oxazole, isoxazole, or pyrazole.

+ cite this

+ View Abstract

Ashton WT, Sisco RM, Dong H, Lyons KA, He H, Doss GA, Leiting B, Patel RA, Wu JK, Marsilio F, Thornberry NA, and Weber AE

Bioorganic & medicinal chemistry letters 15(9):2253-8, 2005 May 2 - Who cited this? | PubMed ID: 15837304 | Fulltext

(2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: a potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.

+ cite this

+ View Abstract

Kim D, Wang L, Beconi M, Eiermann GJ, Fisher MH, He H, Hickey GJ, Kowalchick JE, Leiting B, Lyons K, Marsilio F, McCann ME, Patel RA, Petrov A, Scapin G, Patel SB,

(show remaining authors)

Journal of medicinal chemistry 48(1):141-51, 2005 Jan 13 - Who cited this? | PubMed ID: 15634008 | Fulltext

Potent and selective proline derived dipeptidyl peptidase IV inhibitors.

+ cite this

+ View Abstract

Edmondson SD, Mastracchio A, Beconi M, Colwell LF, Habulihaz B, He H, Kumar S, Leiting B, Lyons KA, Mao A, Marsilio F, Patel RA, Wu JK, Zhu L, Thornberry NA, Weber AE,

(show remaining authors)

Bioorganic & medicinal chemistry letters 14(20):5151-5, 2004 Oct 18 - Who cited this? | PubMed ID: 15380217 | Fulltext

Discovery of potent and selective beta-homophenylalanine based dipeptidyl peptidase IV inhibitors.

+ cite this

+ View Abstract

Xu J, Ok HO, Gonzalez EJ, Colwell LF, Habulihaz B, He H, Leiting B, Lyons KA, Marsilio F, Patel RA, Wu JK, Thornberry NA, Weber AE, and Parmee ER

Bioorganic & medicinal chemistry letters 14(18):4759-62, 2004 Sep 20 - Who cited this? | PubMed ID: 15324903 | Fulltext

Substituted piperazines as novel dipeptidyl peptidase IV inhibitors.

+ cite this

+ View Abstract

Brockunier LL, He J, Colwell LF, Habulihaz B, He H, Leiting B, Lyons KA, Marsilio F, Patel RA, Teffera Y, Wu JK, Thornberry NA, Weber AE, and Parmee ER

Bioorganic & medicinal chemistry letters 14(18):4763-6, 2004 Sep 20 - Who cited this? | PubMed ID: 15324904 | Fulltext

Fluoropyrrolidine amides as dipeptidyl peptidase IV inhibitors.

+ cite this

+ View Abstract

Caldwell CG, Chen P, He J, Parmee ER, Leiting B, Marsilio F, Patel RA, Wu JK, Eiermann GJ, Petrov A, He H, Lyons KA, Thornberry NA, and Weber AE

Bioorganic & medicinal chemistry letters 14(5):1265-8, 2004 Mar 8 - Who cited this? | PubMed ID: 14980678 | Fulltext

Diastereoselective synthesis and configuration-dependent activity of (3-substituted-cycloalkyl)glycine pyrrolidides and thiazolidides as dipeptidyl peptidase IV inhibitors.

+ cite this

+ View Abstract

Ashton WT, Dong H, Sisco RM, Doss GA, Leiting B, Patel RA, Wu JK, Marsilio F, Thornberry NA, and Weber AE

Bioorganic & medicinal chemistry letters 14(4):859-63, 2004 Feb 23 - Who cited this? | PubMed ID: 15012982 | Fulltext

Discovery of novel aspartyl ketone dipeptides as potent and selective caspase-3 inhibitors.

+ cite this

+ View Abstract

Han Y, Giroux A, Grimm EL, Aspiotis R, Francoeur S, Bayly CI, Mckay DJ, Roy S, Xanthoudakis S, Vaillancourt JP, Rasper DM, Tam J, Tawa P, Thornberry NA, Paterson EP, Garcia-Calvo M,

(show remaining authors)

Bioorganic & medicinal chemistry letters 14(3):805-8, 2004 Feb 9 - Who cited this? | PubMed ID: 14741294 | Fulltext

4-Amino cyclohexylglycine analogues as potent dipeptidyl peptidase IV inhibitors.

+ cite this

+ View Abstract

Parmee ER, He J, Mastracchio A, Edmondson SD, Colwell L, Eiermann G, Feeney WP, Habulihaz B, He H, Kilburn R, Leiting B, Lyons K, Marsilio F, Patel RA, Petrov A, Di Salvo J,

(show remaining authors)

Bioorganic & medicinal chemistry letters 14(1):43-6, 2004 Jan 5 - Who cited this? | PubMed ID: 14684294 | Fulltext

The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites.

+ cite this

+ View Abstract

Kisselev AF, Garcia-Calvo M, Overkleeft HS, Peterson E, Pennington MW, Ploegh HL, Thornberry NA, and Goldberg AL

The Journal of biological chemistry 278(38):35869, 2003 Sep 19 - Who cited this? | PubMed ID: 12815064 | Fulltext

Nicotinyl aspartyl ketones as inhibitors of caspase-3.

+ cite this

+ View Abstract

Isabel E, Black WC, Bayly CI, Grimm EL, Janes MK, McKay DJ, Nicholson DW, Rasper DM, Renaud J, Roy S, Tam J, Thornberry NA, Vaillancourt JP, Xanthoudakis S, and Zamboni R

Bioorganic & medicinal chemistry letters 13(13):2137-40, 2003 Jul 7 - Who cited this? | PubMed ID: 12798321 | Fulltext

The role of dipeptidyl peptidase IV in the cleavage of glucagon family peptides: in vivo metabolism of pituitary adenylate cyclase activating polypeptide-(1-38).

+ cite this

+ View Abstract

Zhu L, Tamvakopoulos C, Xie D, Dragovic J, Shen X, Fenyk-Melody JE, Schmidt K, Bagchi A, Griffin PR, Thornberry NA, and Sinha Roy R

The Journal of biological chemistry 278(25):22418-23, 2003 Jun 20 - Who cited this? | PubMed ID: 12690116 | Fulltext

Mice lacking dipeptidyl peptidase IV are protected against obesity and insulin resistance.

+ cite this

+ View Abstract

Conarello SL, Li Z, Ronan J, Roy RS, Zhu L, Jiang G, Liu F, Woods J, Zycband E, Moller DE, Thornberry NA, and Zhang BB

Proceedings of the National Academy of Sciences of the United States of America 100(11):6825-30, 2003 May 27 - Who cited this? | PubMed ID: 12748388 | Fulltext

Catalytic properties and inhibition of proline-specific dipeptidyl peptidases II, IV and VII.

+ cite this

+ View Abstract

Leiting B, Pryor KD, Wu JK, Marsilio F, Patel RA, Craik CS, Ellman JA, Cummings RT, and Thornberry NA

The Biochemical journal 371(Pt 2):525-32, 2003 Apr 15 - Who cited this? | PubMed ID: 12529175 | Fulltext

Apoptosis. Life and death decisions.

+ cite this

Nicholson DW and Thornberry NA

Science (New York, N.Y.) 299(5604):214-5, 2003 Jan 10 - Who cited this? | PubMed ID: 12522239 | Fulltext

Discovery of potent, selective human granzyme B inhibitors that inhibit CTL mediated apoptosis.

+ cite this

+ View Abstract

Willoughby CA, Bull HG, Garcia-Calvo M, Jiang J, Chapman KT, and Thornberry NA

Bioorganic & medicinal chemistry letters 12(16):2197-200, 2002 Aug 19 - Who cited this? | PubMed ID: 12127536 | Fulltext

Adenovirus L4-100K assembly protein is a granzyme B substrate that potently inhibits granzyme B-mediated cell death.

+ cite this

+ View Abstract

Andrade F, Bull HG, Thornberry NA, Ketner GW, Casciola-Rosen LA, and Rosen A

Immunity 14(6):751-61, 2001 Jun - Who cited this? | PubMed ID: 11420045 | Fulltext

Maintenance of caspase-3 proenzyme dormancy by an intrinsic "safety catch" regulatory tripeptide.

+ cite this

+ View Abstract

Roy S, Bayly CI, Gareau Y, Houtzager VM, Kargman S, Keen SL, Rowland K, Seiden IM, Thornberry NA, and Nicholson DW

Proceedings of the National Academy of Sciences of the United States of America 98(11):6132-7, 2001 May 22 - Who cited this? | PubMed ID: 11353841 | Fulltext

The three-dimensional structure of human granzyme B compared to caspase-3, key mediators of cell death with cleavage specificity for aspartic acid in P1.

+ cite this

+ View Abstract

Rotonda J, Garcia-Calvo M, Bull HG, Geissler WM, McKeever BM, Willoughby CA, Thornberry NA, and Becker JW

Chemistry & biology 8(4):357-68, 2001 Apr - Who cited this? | PubMed ID: 11325591 | Fulltext

Search Google Scholar for Thornberry NA

Join Labmeeting

Organize and search your PDF collection
Collect papers
Search millions of papers
Keep up to date with paper alerts
Read your papers from anywhere
Recommend papers to colleagues
Manage your lab

Labmeeting is a web service for researchers. Sign up with your academic email address.

Individuals or corporations not affiliated with an academic institution can request a trial subscription.

Papers authored by Thornberry NA

Join Labmeeting

Sponsored Product