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Papers authored by Theakston RD

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Apparent marked reduction in early antivenom reactions compared to historical controls: was it prophylaxis or method of administration?.

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Caron EJ, Manock SR, Maudlin J, Koleski J, Theakston RD, Warrell DA, and Smalligan RD

Toxicon : official journal of the International Society on Toxinology 54(6):779-83, 2009 Nov - Who cited this? | PubMed ID: 19520099 | Fulltext

Syndromic approach to treatment of snake bite in Sri Lanka based on results of a prospective national hospital-based survey of patients envenomed by identified snakes.

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Ariaratnam CA, Sheriff MH, Arambepola C, Theakston RD, and Warrell DA

The American journal of tropical medicine and hygiene 81(4):725-31, 2009 Oct - Who cited this? | PubMed ID: 19815895 | Fulltext

Frequent and potentially fatal envenoming by hump-nosed pit vipers (Hypnale hypnale and H. nepa) in Sri Lanka: lack of effective antivenom.

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Ariaratnam CA, Thuraisingam V, Kularatne SA, Sheriff MH, Theakston RD, de Silva A, and Warrell DA

Transactions of the Royal Society of Tropical Medicine and Hygiene 102(11):1120-6, 2008 Nov - Who cited this? | PubMed ID: 18455743 | Fulltext

Distinctive Epidemiologic and Clinical Features of Common Krait (Bungarus caeruleus) Bites in Sri Lanka.

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Ariaratnam CA, Sheriff MH, Theakston RD, and Warrell DA

The American journal of tropical medicine and hygiene 79(3):458-62, 2008 Sep - Who cited this? | PubMed ID: 18784244 | Fulltext

Envenoming after carpet viper (Echis ocellatus) bite during pregnancy: timely use of effective antivenom improves maternal and foetal outcomes.

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Habib AG, Abubakar SB, Abubakar IS, Larnyang S, Durfa N, Nasidi A, Yusuf PO, Garnvwa J, Theakston RD, Salako L, Warrell DA, and EchiTab Study Group (Nigeria & UK)

Tropical medicine & international health : TM & IH 13(9):1172-5, 2008 Sep - Who cited this? | PubMed ID: 18631310 | Fulltext

Haematological evaluation of patients bitten by the jararaca, Bothrops jararaca, in Brazil.

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Santoro ML, Sano-Martins IS, Fan HW, Cardoso JL, Theakston RD, Warrell DA, and BIASG

Toxicon : official journal of the International Society on Toxinology 51(8):1440-8, 2008 Jun 15 - Who cited this? | PubMed ID: 18471839 | Fulltext

Neutralization of the haemorrhagic activities of viperine snake venoms and venom metalloproteinases using synthetic peptide inhibitors and chelators.

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Howes JM, Theakston RD, and Laing GD

Toxicon : official journal of the International Society on Toxinology 49(5):734, 2007 Apr - Who cited this? | PubMed ID: 17196631 | Fulltext

Efficacy and safety of two whole IgG polyvalent antivenoms, refined by caprylic acid fractionation with or without beta-propiolactone, in the treatment of Bothrops asper bites in Colombia.

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Otero R, León G, Gutiérrez JM, Rojas G, Toro MF, Barona J, Rodríguez V, Díaz A, Núñez V, Quintana JC, Ayala S, Mosquera D, Conrado LL, Fernández D, Arroyo Y, Paniagua CA,

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Transactions of the Royal Society of Tropical Medicine and Hygiene 100(12):1173-82, 2006 Dec - Who cited this? | PubMed ID: 16698053 | Fulltext

Functional expression and purification of recombinant Tx1, a sodium channel blocker neurotoxin from the venom of the Brazilian "armed" spider, Phoneutria nigriventer.

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Diniz MR, Theakston RD, Crampton JM, Nascimento Cordeiro M, Pimenta AM, De Lima ME, and Diniz CR

Protein expression and purification 50(1):18-24, 2006 Nov - Who cited this? | PubMed ID: 16908187 | Fulltext

Parasitologists lost?.

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Barnish G, Crewe W, and Theakston RD

Trends in parasitology 22(10):454-5, 2006 Oct - Who cited this? | PubMed ID: 16901754 | Fulltext

Bioinformatics and multiepitope DNA immunization to design rational snake antivenom.

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Wagstaff SC, Laing GD, Theakston RD, Papaspyridis C, and Harrison RA

PLoS medicine 3(6):e184, 2006 Jun - Who cited this? | PubMed ID: 16737347 | Fulltext

Confronting the neglected problem of snake bite envenoming: the need for a global partnership.

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Gutiérrez JM, Theakston RD, and Warrell DA

PLoS medicine 3(6):e150, 2006 Jun - Who cited this? | PubMed ID: 16729843 | Fulltext

Isolation and characterization of cotiaractivase, a novel low molecular weight prothrombin activator from the venom of Bothrops cotiara.

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Senis YA, Kim PY, Fuller GL, García A, Prabhakar S, Wilkinson MC, Brittan H, Zitzmann N, Wait R, Warrell DA, Watson SP, Kamiguti AS, Theakston RD, Nesheim ME, and Laing GD

Biochimica et biophysica acta 1764(5):863-71, 2006 May - Who cited this? | PubMed ID: 16647309 | Fulltext

Neutralisation of venom-induced haemorrhage by IgG from camels and llamas immunised with viper venom and also by endogenous, non-IgG components in camelid sera.

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Harrison RA, Hasson SS, Harmsen M, Laing GD, Conrath K, and Theakston RD

Toxicon : official journal of the International Society on Toxinology 47(3):364-8, 2006 Mar - Who cited this? | PubMed ID: 16359717 | Fulltext

A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.

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Suzuki-Inoue K, Fuller GL, García A, Eble JA, Pöhlmann S, Inoue O, Gartner TK, Hughan SC, Pearce AC, Laing GD, Theakston RD, Schweighoffer E, Zitzmann N, Morita T, Tybulewicz VL, Ozaki Y,

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Blood 107(2):542-9, 2006 Jan 15 - Who cited this? | PubMed ID: 16174766 | Fulltext

Characterization of a novel protein from Proatheris superciliaris venom: proatherocytin, a 34-kDa platelet receptor PAR1 agonist.

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Laing GD, Compton SJ, Ramachandran R, Fuller GL, Wilkinson MC, Wagstaff SC, Watson SP, Kamiguti AS, Theakston RD, and Senis YA

Toxicon : official journal of the International Society on Toxinology 46(5):490-9, 2005 Oct - Who cited this? | PubMed ID: 16112700 | Fulltext

Role of the snake venom toxin jararhagin in proinflammatory pathogenesis: in vitro and in vivo gene expression analysis of the effects of the toxin.

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Gallagher P, Bao Y, Serrano SM, Laing GD, Theakston RD, Gutiérrez JM, Escalante T, Zigrino P, Moura-da-Silva AM, Nischt R, Mauch C, Moskaluk C, and Fox JW

Archives of biochemistry and biophysics 441(1):1-15, 2005 Sep 1 - Who cited this? | PubMed ID: 16083850 | Fulltext

Effects of three novel metalloproteinases from the venom of the West African saw-scaled viper, Echis ocellatus on blood coagulation and platelets.

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Howes JM, Kamiguti AS, Theakston RD, Wilkinson MC, and Laing GD

Biochimica et biophysica acta 1724(1-2):194-202, 2005 Jun 20 - Who cited this? | PubMed ID: 15863354 | Fulltext

Pan-African polyspecific antivenom produced by caprylic acid purification of horse IgG: an alternative to the antivenom crisis in Africa.

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Gutiérrez JM, Rojas E, Quesada L, León G, Núñez J, Laing GD, Sasa M, Renjifo JM, Nasidi A, Warrell DA, Theakston RD, and Rojas G

Transactions of the Royal Society of Tropical Medicine and Hygiene 99(6):468-75, 2005 Jun - Who cited this? | PubMed ID: 15837359 | Fulltext

Antigenic relationships and relative immunogenicities of isolated metalloproteinases from Echis ocellatus venom.

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Howes JM, Theakston RD, and Laing GD

Toxicon : official journal of the International Society on Toxinology 45(5):677-80, 2005 Apr - Who cited this? | PubMed ID: 15777964 | Fulltext

Crotaline snake bite in the Ecuadorian Amazon: randomised double blind comparative trial of three South American polyspecific antivenoms.

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Smalligan R, Cole J, Brito N, Laing GD, Mertz BL, Manock S, Maudlin J, Quist B, Holland G, Nelson S, Lalloo DG, Rivadeneira G, Barragan ME, Dolley D, Eddleston M, Warrell DA,

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BMJ (Clinical research ed.) 329(7475):1129, 2004 Nov 13 - Who cited this? | PubMed ID: 15539665 | Fulltext

Life-threatening envenoming by the Saharan horned viper (Cerastes cerastes) causing micro-angiopathic haemolysis, coagulopathy and acute renal failure: clinical cases and review.

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Schneemann M, Cathomas R, Laidlaw ST, El Nahas AM, Theakston RD, and Warrell DA

QJM : monthly journal of the Association of Physicians 97(11):717-27, 2004 Nov - Who cited this? | PubMed ID: 15496528 | Fulltext

Failure of chloramphenicol prophylaxis to reduce the frequency of abscess formation as a complication of envenoming by Bothrops snakes in Brazil: a double-blind randomized controlled trial.

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Jorge MT, Malaque C, Ribeiro LA, Fan HW, Cardoso JL, Nishioka SA, Sano-Martins IS, França FO, Kamiguti AS, Theakston RD, and Warrell DA

Transactions of the Royal Society of Tropical Medicine and Hygiene 98(9):529-34, 2004 Sep - Who cited this? | PubMed ID: 15251401 | Fulltext

Antibody zymography: a novel adaptation of zymography to determine the protease-neutralising potential of specific antibodies and snake antivenoms.

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Hasson SS, Theakston RD, and Harrison RA

Journal of immunological methods 292(1-2):131-9, 2004 Sep - Who cited this? | PubMed ID: 15350518 | Fulltext

Preclinical testing of three South American antivenoms against the venoms of five medically-important Peruvian snake venoms.

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Laing GD, Yarleque A, Marcelo A, Rodriguez E, Warrell DA, and Theakston RD

Toxicon : official journal of the International Society on Toxinology 44(1):103-6, 2004 Jul - Who cited this? | PubMed ID: 15225568 | Fulltext

Structural requirements of MLD-containing disintegrins for functional interaction with alpha 4 beta 1 and alpha 9 beta1 integrins.

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Bazan-Socha S, Kisiel DG, Young B, Theakston RD, Calvete JJ, Sheppard D, and Marcinkiewicz C

Biochemistry 43(6):1639-47, 2004 Feb 17 - Who cited this? | PubMed ID: 14769041 | Fulltext

Bothrops asper metalloproteinase BaP1 is inhibited by alpha(2)-macroglobulin and mouse serum and does not induce systemic hemorrhage or coagulopathy.

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Escalante T, Rucavado A, Kamiguti AS, Theakston RD, and Gutiérrez JM

Toxicon : official journal of the International Society on Toxinology 43(2):213-7, 2004 Feb - Who cited this? | PubMed ID: 15019481 | Fulltext

Clinical trial of two antivenoms for the treatment of Bothrops and Lachesis bites in the north eastern Amazon region of Brazil.

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Pardal PP, Souza SM, Monteiro MR, Fan HW, Cardoso JL, França FO, Tomy SC, Sano-Martins IS, de Sousa-e-Silva MC, Colombini M, Kodera NF, Moura-da-Silva AM, Cardoso DF, Velarde DT, Kamiguti AS, Theakston RD,

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Transactions of the Royal Society of Tropical Medicine and Hygiene 98(1):28-42, 2004 Jan - Who cited this? | PubMed ID: 14702836 | Fulltext

Inflammatory pathogenesis of snake venom metalloproteinase-induced skin necrosis.

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Laing GD, Clissa PB, Theakston RD, Moura-da-Silva AM, and Taylor MJ

European journal of immunology 33(12):3458-63, 2003 Dec - Who cited this? | PubMed ID: 14635056 | Fulltext

Pulmonary hemorrhage induced by jararhagin, a metalloproteinase from Bothrops jararaca snake venom.

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Escalante T, Núñez J, Moura da Silva AM, Rucavado A, Theakston RD, and Gutiérrez JM

Toxicology and applied pharmacology 193(1):17-28, 2003 Nov 15 - Who cited this? | PubMed ID: 14613713 | Fulltext

Cloning of a prothrombin activator-like metalloproteinase from the West African saw-scaled viper, Echis ocellatus.

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Hasson SS, Theakston RD, and Harrison RA

Toxicon : official journal of the International Society on Toxinology 42(6):629-34, 2003 Nov - Who cited this? | PubMed ID: 14602118 | Fulltext

Novel sequences encoding venom C-type lectins are conserved in phylogenetically and geographically distinct Echis and Bitis viper species.

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Harrison RA, Oliver J, Hasson SS, Bharati K, and Theakston RD

Gene 315:95-102, 2003 Oct 2 - Who cited this? | PubMed ID: 14557069 | Fulltext

Characterization of 'basparin A,' a prothrombin-activating metalloproteinase, from the venom of the snake Bothrops asper that inhibits platelet aggregation and induces defibrination and thrombosis.

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Loría GD, Rucavado A, Kamiguti AS, Theakston RD, Fox JW, Alape A, and Gutiérrez JM

Archives of biochemistry and biophysics 418(1):13-24, 2003 Oct 1 - Who cited this? | PubMed ID: 13679078 | Fulltext

Amino acid sequence and crystal structure of BaP1, a metalloproteinase from Bothrops asper snake venom that exerts multiple tissue-damaging activities.

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Watanabe L, Shannon JD, Valente RH, Rucavado A, Alape-Girón A, Kamiguti AS, Theakston RD, Fox JW, Gutiérrez JM, and Arni RK

Protein science : a publication of the Protein Society 12(10):2273-81, 2003 Oct - Who cited this? | PubMed ID: 14500885 | Fulltext

In vitro procoagulant and anticoagulant properties of Naja naja naja venom.

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Sundell IB, Rånby M, Zuzel M, Robinson KA, and Theakston RD

Toxicon : official journal of the International Society on Toxinology 42(3):239-47, 2003 Sep - Who cited this? | PubMed ID: 14559074 | Fulltext

Identification of sites in the cysteine-rich domain of the class P-III snake venom metalloproteinases responsible for inhibition of platelet function.

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Kamiguti AS, Gallagher P, Marcinkiewicz C, Theakston RD, Zuzel M, and Fox JW

FEBS letters 549(1-3):129-34, 2003 Aug 14 - Who cited this? | PubMed ID: 12914938 | Fulltext

The purification and partial characterisation of two novel metalloproteinases from the venom of the West African carpet viper, Echis ocellatus.

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Howes JM, Wilkinson MC, Theakston RD, and Laing GD

Toxicon : official journal of the International Society on Toxinology 42(1):21-7, 2003 Jul - Who cited this? | PubMed ID: 12893057 | Fulltext

A new Pan African polyspecific antivenom developed in response to the antivenom crisis in Africa.

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Laing GD, Renjifo JM, Ruiz F, Harrison RA, Nasidi A, Gutierrez JM, Rowley PD, Warrell DA, and Theakston RD

Toxicon : official journal of the International Society on Toxinology 42(1):35-41, 2003 Jul - Who cited this? | PubMed ID: 12893059 | Fulltext

Snake venom disintegrins: novel dimeric disintegrins and structural diversification by disulphide bond engineering.

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Calvete JJ, Moreno-Murciano MP, Theakston RD, Kisiel DG, and Marcinkiewicz C

The Biochemical journal 372(Pt 3):725-34, 2003 Jun 15 - Who cited this? | PubMed ID: 12667142 | Fulltext

Molecular cloning of phospholipases A(2) from venom glands of Echis carpet vipers.

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Bharati K, Hasson SS, Oliver J, Laing GD, Theakston RD, and Harrison RA

Toxicon : official journal of the International Society on Toxinology 41(8):941-7, 2003 Jun - Who cited this? | PubMed ID: 12875867 | Fulltext

Report of a WHO workshop on the standardization and control of antivenoms.

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Theakston RD, Warrell DA, and Griffiths E

Toxicon : official journal of the International Society on Toxinology 41(5):541-57, 2003 Apr - Who cited this? | PubMed ID: 12676433 | Fulltext

Use of microarrays for investigating the subtoxic effects of snake venoms: insights into venom-induced apoptosis in human umbilical vein endothelial cells.

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Gallagher PG, Bao Y, Serrano SM, Kamiguti AS, Theakston RD, and Fox JW

Toxicon : official journal of the International Society on Toxinology 41(4):429-40, 2003 Mar - Who cited this? | PubMed ID: 12657312 | Fulltext

The conserved structure of snake venom toxins confers extensive immunological cross-reactivity to toxin-specific antibody.

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Harrison RA, Wüster W, and Theakston RD

Toxicon : official journal of the International Society on Toxinology 41(4):441-9, 2003 Mar - Who cited this? | PubMed ID: 12657313 | Fulltext

The role of phospholipases A2 in the stimulation of neutrophil motility by cobra venoms.

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Sundell IB, Aziz KA, Zuzel M, and Theakston RD

Toxicon : official journal of the International Society on Toxinology 41(4):459-68, 2003 Mar - Who cited this? | PubMed ID: 12657315 | Fulltext

Polyspecific snake antivenom may help in antivenom crisis.

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Laing GD, Harrison RA, Theakston RD, Renjifo JM, Nasidi A, Gutierrez JM, and Warrell DA

BMJ (Clinical research ed.) 326(7386):447, 2003 Feb 22 - Who cited this? | PubMed ID: 12595392 | Fulltext

Snake antivenoms.

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Lalloo DG and Theakston RD

Journal of toxicology. Clinical toxicology 41(3):277-90; 317-27, 2003 - Who cited this? | PubMed ID: 12807311 | Fulltext

Geographic Information System mapping of snakebite incidence in northern Ghana and Nigeria using environmental indicators: a preliminary study.

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Molesworth AM, Harrison R, Theakston RD, and Lalloo DG

Transactions of the Royal Society of Tropical Medicine and Hygiene 97(2):188-92, 2003 - Who cited this? | PubMed ID: 14584375 | Fulltext

Envenoming by Bothrops jararaca in Brazil: association between venom antigenaemia and severity at admission to hospital.

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França FO, Barbaro KC, Fan HW, Cardoso JL, Sano-Martins IS, Tomy SC, Lopes MH, Warrell DA, Theakston RD, and Butantan Institute Antivenom Study Group

Transactions of the Royal Society of Tropical Medicine and Hygiene 97(3):312-7, 2003 - Who cited this? | PubMed ID: 15228251 | Fulltext

Crystallization and preliminary diffraction data of BaP1, a haemorrhagic metalloproteinase from Bothrops asper snake venom.

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Watanabe L, Rucavado A, Kamiguti A, Theakston RD, Gutiérrez JM, and Arni RK

Acta crystallographica. Section D, Biological crystallography 58(Pt 6 Pt 2):1034-5, 2002 Jun - Who cited this? | PubMed ID: 12037308 | Fulltext

A list of animal toxins and some other natural products with biological activity.

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Theakston RD and Kamiguti AS

Toxicon : official journal of the International Society on Toxinology 40(5):579-651, 2002 May - Who cited this? | PubMed ID: 11951814 | Fulltext

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Papers authored by Theakston RD

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