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Papers authored by Tamagnan G

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SPECT imaging of nicotinic acetylcholine receptors in nonsmoking heavy alcohol drinking individuals.

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Esterlis I, Cosgrove KP, Petrakis IL, McKee SA, Bois F, Krantzler E, Stiklus SM, Perry EB, Tamagnan GD, Seibyl JP, Krystal JH, and Staley JK

Drug and alcohol dependence 108(1-2):146-50, 2010 Apr 1 - Who cited this? | PubMed ID: 20074869 | Fulltext

GABAA-benzodiazepine receptor availability in smokers and nonsmokers: relationship to subsyndromal anxiety and depression.

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Esterlis I, Cosgrove KP, Batis JC, Bois F, Kloczynski TA, Stiklus SM, Perry E, Tamagnan GD, Seibyl JP, Makuch R, Krishnan-Sarin S, O'Malley S, and Staley JK

Synapse (New York, N.Y.) 63(12):1089-99, 2009 Dec - Who cited this? | PubMed ID: 19642218 | Fulltext

Regional distribution and behavioral correlates of 5-HT(2A) receptors in Alzheimer's disease with [(18)F]deuteroaltanserin and PET.

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Santhosh L, Estok KM, Vogel RS, Tamagnan GD, Baldwin RM, Mitsis EM, Macavoy MG, Staley JK, and van Dyck CH

Psychiatry research 173(3):212-7, 2009 Sep 30 - Who cited this? | PubMed ID: 19682865 | Fulltext

Age-related decline in nicotinic receptor availability with [(123)I]5-IA-85380 SPECT.

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Mitsis EM, Cosgrove KP, Staley JK, Bois F, Frohlich EB, Tamagnan GD, Estok KM, Seibyl JP, and van Dyck CH

Neurobiology of aging 30(9):1490-7, 2009 Sep - Who cited this? | PubMed ID: 18242781 | Fulltext

Dopamine and serotonin transporter availability during acute alcohol withdrawal: effects of comorbid tobacco smoking.

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Cosgrove KP, Krantzler E, Frohlich EB, Stiklus S, Pittman B, Tamagnan GD, Baldwin RM, Bois F, Seibyl JP, Krystal JH, O'Malley SS, and Staley JK

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 34(10):2218-26, 2009 Sep - Who cited this? | PubMed ID: 19440191 | Fulltext

123I-5-IA-85380 SPECT imaging of nicotinic receptors in Alzheimer disease and mild cognitive impairment.

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Mitsis EM, Reech KM, Bois F, Tamagnan GD, Macavoy MG, Seibyl JP, Staley JK, and van Dyck CH

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 50(9):1455-63, 2009 Sep - Who cited this? | PubMed ID: 19690024 | Fulltext

beta2-Nicotinic acetylcholine receptor availability during acute and prolonged abstinence from tobacco smoking.

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Cosgrove KP, Batis J, Bois F, Maciejewski PK, Esterlis I, Kloczynski T, Stiklus S, Krishnan-Sarin S, O'Malley S, Perry E, Tamagnan G, Seibyl JP, and Staley JK

Archives of general psychiatry 66(6):666-76, 2009 Jun - Who cited this? | PubMed ID: 19487632 | Fulltext

Synthesis of 5- and 6-substituted 2-(4-dimethylaminophenyl)-1,3-benzoxazoles and their in vitro and in vivo evaluation as imaging agents for amyloid plaque.

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Hausner SH, Alagille D, Koren AO, Amici L, Staley JK, Cosgrove KP, Baldwin RM, and Tamagnan GD

Bioorganic & medicinal chemistry letters 19(2):543-5, 2009 Jan 15 - Who cited this? | PubMed ID: 19081717 | Fulltext

Synthesis, radiosynthesis, and biological evaluation of carbon-11 and fluorine-18 labeled reboxetine analogues: potential positron emission tomography radioligands for in vivo imaging of the norepinephrine transporter.

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Zeng F, Mun J, Jarkas N, Stehouwer JS, Voll RJ, Tamagnan GD, Howell L, Votaw JR, Kilts CD, Nemeroff CB, and Goodman MM

Journal of medicinal chemistry 52(1):62-73, 2009 Jan 8 - Who cited this? | PubMed ID: 19067522 | Fulltext

Biomarkers for Parkison's disease: tools to assess Parkinson's disease onset and progression.

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Marek K, Jennings D, Tamagnan G, and Seibyl J

Annals of neurology 64 Suppl 2:S111-21, 2008 Dec - Who cited this? | PubMed ID: 19127587 | Fulltext

Microwave-induced nucleophilic [(18)F]fluorination on aromatic rings: Synthesis and effect of halogen on [(18)F]fluoride substitution of meta-halo (F, Cl, Br, I)-benzonitrile derivatives.

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Guo N, Alagille D, Tamagnan G, Price RR, and Baldwin RM

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 66(10):1396-402, 2008 Oct - Who cited this? | PubMed ID: 18417350 | Fulltext

beta2 Nicotinic acetylcholine receptor availability in post-traumatic stress disorder.

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Czermak C, Staley JK, Kasserman S, Bois F, Young T, Henry S, Tamagnan GD, Seibyl JP, Krystal JH, and Neumeister A

The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 11(3):419-24, 2008 Jun - Who cited this? | PubMed ID: 18190729 | Fulltext

Synthesis, radiolabeling and baboon SPECT imaging of 2beta-carbomethoxy-3beta-(3'-[(123)I]iodophenyl)tropane ([(123)I]YP256) as a serotonin transporter radiotracer.

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Bois F, Baldwin RM, Amici L, Al-Tikriti MS, Kula N, Baldessarini R, Innis RB, Staley JK, and Tamagnan GD

Nuclear medicine and biology 35(1):53-9, 2008 Jan - Who cited this? | PubMed ID: 18158943 | Fulltext

Positive allosteric modulation of metabotropic glutamate 5 (mGlu5) receptors reverses N-Methyl-D-aspartate antagonist-induced alteration of neuronal firing in prefrontal cortex.

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Lecourtier L, Homayoun H, Tamagnan G, and Moghaddam B

Biological psychiatry 62(7):739-46, 2007 Oct 1 - Who cited this? | PubMed ID: 17511968 | Fulltext

123I-5-IA-85380 SPECT imaging of nicotinic acetylcholine receptor availability in nonsmokers: effects of sex and menstrual phase.

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Cosgrove KP, Mitsis EM, Bois F, Frohlich E, Tamagnan GD, Krantzler E, Perry E, Maciejewski PK, Epperson CN, Allen S, O'malley S, Mazure CM, Seibyl JP, van Dyck CH, and Staley JK

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 48(10):1633-40, 2007 Oct - Who cited this? | PubMed ID: 17873128 | Fulltext

A novel family of potent negative allosteric modulators of group II metabotropic glutamate receptors.

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Hemstapat K, Da Costa H, Nong Y, Brady AE, Luo Q, Niswender CM, Tamagnan GD, and Conn PJ

The Journal of pharmacology and experimental therapeutics 322(1):254-64, 2007 Jul - Who cited this? | PubMed ID: 17416742 | Fulltext

[123I]5-IA-85380 SPECT imaging of beta2-nicotinic acetylcholine receptor availability in the aging human brain.

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Mitsis EM, Cosgrove KP, Staley JK, Frohlich EB, Bois F, Tamagnan GD, Estok KM, Seibyl JP, and Van Dyck CH

Annals of the New York Academy of Sciences 1097:168-70, 2007 Feb - Who cited this? | PubMed ID: 17413019 | Fulltext

Development of SPECT imaging agents for the norepinephrine transporters: [123I]INER.

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Tamagnan GD, Brenner E, Alagille D, Staley JK, Haile C, Koren A, Early M, Baldwin RM, Tarazi FI, Baldessarini RJ, Jarkas N, Goodman MM, and Seibyl JP

Bioorganic & medicinal chemistry letters 17(2):533-7, 2007 Jan 15 - Who cited this? | PubMed ID: 17095215 | Fulltext

Synthesis and receptor binding studies of halogenated N,N-dialkylel-(2-phenyl-1H-indol-3-yl)glyoxylamides to visualize peripheral benzodiazepine receptors with SPECT or PET.

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Bennacef I, Haile CN, Schmidt A, Koren AO, Seibyl JP, Staley JK, Bois F, Baldwin RM, and Tamagnan G

Bioorganic & medicinal chemistry 14(22):7582-91, 2006 Nov 15 - Who cited this? | PubMed ID: 16908169 | Fulltext

Synthesis and monoamine transporter affinity of 2beta-carbomethoxy-3beta-(4'-p-substituted phenyl)-piperidine analogs of cocaine.

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Bois F, Baldwin RM, Kula NS, Baldessarini RJ, Al Tikriti M, Innis RB, and Tamagnan GD

Bioorganic & medicinal chemistry letters 16(19):5222-5, 2006 Oct 1 - Who cited this? | PubMed ID: 16908151 | Fulltext

Human tobacco smokers in early abstinence have higher levels of beta2* nicotinic acetylcholine receptors than nonsmokers.

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Staley JK, Krishnan-Sarin S, Cosgrove KP, Krantzler E, Frohlich E, Perry E, Dubin JA, Estok K, Brenner E, Baldwin RM, Tamagnan GD, Seibyl JP, Jatlow P, Picciotto MR, London ED, O'Malley S,

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The Journal of neuroscience : the official journal of the Society for Neuroscience 26(34):8707-14, 2006 Aug 23 - Who cited this? | PubMed ID: 16928859 | Fulltext

A novel class of positive allosteric modulators of metabotropic glutamate receptor subtype 1 interact with a site distinct from that of negative allosteric modulators.

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Hemstapat K, de Paulis T, Chen Y, Brady AE, Grover VK, Alagille D, Tamagnan GD, and Conn PJ

Molecular pharmacology 70(2):616, 2006 Aug - Who cited this? | PubMed ID: 16645124 | Fulltext

Substituent effects of N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides on positive allosteric modulation of the metabotropic glutamate-5 receptor in rat cortical astrocytes.

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de Paulis T, Hemstapat K, Chen Y, Zhang Y, Saleh S, Alagille D, Baldwin RM, Tamagnan GD, and Conn PJ

Journal of medicinal chemistry 49(11):3332-44, 2006 Jun 1 - Who cited this? | PubMed ID: 16722652 | Fulltext

Chemical fate of the nicotinic acetylcholinergic radiotracer [123I]5-IA-85380 in baboon brain and plasma.

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Baldwin RM, Zoghbi SS, Staley JK, Brenner E, Al-Tikriti MS, Amici L, Fujita M, Innis RB, and Tamagnan G

Nuclear medicine and biology 33(4):549-54, 2006 May - Who cited this? | PubMed ID: 16720248 | Fulltext

Synthesis and monoamine transporter affinity of new 2beta-carbomethoxy-3beta-[aryl or heteroaryl]phenyltropanes.

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Tamagnan G, Alagille D, Fu X, Kula NS, Baldessarini RJ, Innis RB, and Baldwin RM

Bioorganic & medicinal chemistry letters 16(1):217-20, 2006 Jan 1 - Who cited this? | PubMed ID: 16236497 | Fulltext

Sex differences in diencephalon serotonin transporter availability in major depression.

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Staley JK, Sanacora G, Tamagnan G, Maciejewski PK, Malison RT, Berman RM, Vythilingam M, Kugaya A, Baldwin RM, Seibyl JP, Charney D, and Innis RB

Biological psychiatry 59(1):40-7, 2006 Jan 1 - Who cited this? | PubMed ID: 16139815 | Fulltext

A close structural analog of 2-methyl-6-(phenylethynyl)-pyridine acts as a neutral allosteric site ligand on metabotropic glutamate receptor subtype 5 and blocks the effects of multiple allosteric modulators.

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Rodriguez AL, Nong Y, Sekaran NK, Alagille D, Tamagnan GD, and Conn PJ

Molecular pharmacology 68(6):1793-802, 2005 Dec - Who cited this? | PubMed ID: 16155210 | Fulltext

Synthesis, radiosynthesis, and biological evaluation of carbon-11 and fluorine-18 (N-fluoroalkyl) labeled 2beta-carbomethoxy-3beta-(4'-(3-furyl)phenyl)tropanes and -nortropanes: candidate radioligands for in vivo imaging of the serotonin transporter with positron emission tomography.

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Stehouwer JS, Plisson C, Jarkas N, Zeng F, Voll RJ, Williams L, Martarello L, Votaw JR, Tamagnan G, and Goodman MM

Journal of medicinal chemistry 48(22):7080-3, 2005 Nov 3 - Who cited this? | PubMed ID: 16250668 | Fulltext

123I-5-IA-85380 SPECT measurement of nicotinic acetylcholine receptors in human brain by the constant infusion paradigm: feasibility and reproducibility.

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Staley JK, van Dyck CH, Weinzimmer D, Brenner E, Baldwin RM, Tamagnan GD, Riccardi P, Mitsis E, and Seibyl JP

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 46(9):1466-72, 2005 Sep - Who cited this? | PubMed ID: 16157529 | Fulltext

Asymmetric synthesis of (+)-(S,S)-reboxetine via a new (S)-2-(hydroxymethyl)morpholine preparation.

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Brenner E, Baldwin RM, and Tamagnan G

Organic letters 7(5):937-9, 2005 Mar 3 - Who cited this? | PubMed ID: 15727479 | Fulltext

Functionalization at position 3 of the phenyl ring of the potent mGluR5 noncompetitive antagonists MPEP.

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Alagille D, Baldwin RM, Roth BL, Wroblewski JT, Grajkowska E, and Tamagnan GD

Bioorganic & medicinal chemistry letters 15(4):945-9, 2005 Feb 15 - Who cited this? | PubMed ID: 15686891 | Fulltext

Synthesis and monoamine transporter affinity of new 2beta-carbomethoxy-3beta-[4-(substituted thiophenyl)]phenyltropanes: discovery of a selective SERT antagonist with picomolar potency.

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Tamagnan G, Alagille D, Fu X, Kula NS, Baldessarini RJ, Innis RB, and Baldwin RM

Bioorganic & medicinal chemistry letters 15(4):1131-3, 2005 Feb 15 - Who cited this? | PubMed ID: 15686927 | Fulltext

Synthesis and receptor assay of aromatic-ethynyl-aromatic derivatives with potent mGluR5 antagonist activity.

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Alagille D, Baldwin RM, Roth BL, Wroblewski JT, Grajkowska E, and Tamagnan GD

Bioorganic & medicinal chemistry 13(1):197-209, 2005 Jan 3 - Who cited this? | PubMed ID: 15582465 | Fulltext

Synthesis and monoamine transporter affinity of 3'-analogs of 2-beta-carbomethoxy-3-beta-(4'-iodophenyl)tropane (beta-CIT).

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Bois F, Baldwin RM, Kula NS, Baldessarini RJ, Innis RB, and Tamagnan G

Bioorganic & medicinal chemistry letters 14(9):2117-20, 2004 May 3 - Who cited this? | PubMed ID: 15080991 | Fulltext

Local anesthetic effects of cocaethylene and isopropylcocaine on rat peripheral nerves.

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Tokuno HA, Bradberry CW, Everill B, Agulian SK, Wilkes S, Baldwin RM, Tamagnan GD, and Kocsis JD

Brain research 996(2):159-67, 2004 Jan 23 - Who cited this? | PubMed ID: 14697493 | Fulltext

Radiosynthesis of [18F] N-(3-Fluoropropyl)-2-beta-Carbomethoxy-3-beta-(4-Bromophenyl) Nortropane and the regional brain uptake in non human primate using PET.

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Chaly T, Baldwin RM, Neumeyer JL, Hellman MJ, Dhawan V, Garg PK, Tamagnan G, Staley JK, Al-Tikriti MS, Hou Y, Zoghbi SS, Gu XH, Zong R, and Eidelberg D

Nuclear medicine and biology 31(1):125-31, 2004 Jan - Who cited this? | PubMed ID: 14741577 | Fulltext

Quantification of nicotinic acetylcholine receptors in human brain using [123I]5-I-A-85380 SPET.

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Fujita M, Ichise M, van Dyck CH, Zoghbi SS, Tamagnan G, Mukhin AG, Bozkurt A, Seneca N, Tipre D, DeNucci CC, Iida H, Vaupel DB, Horti AG, Koren AO, Kimes AS, London ED,

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European journal of nuclear medicine and molecular imaging 30(12):1620-9, 2003 Dec - Who cited this? | PubMed ID: 14523584 | Fulltext

Synthesis and affinity of a possible byproduct of electrophilic radiolabeling of [123I]IBZM.

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Baldwin RM, Fu X, Kula NS, Baldessarini RJ, Amici L, Innis RB, and Tamagnan GD

Bioorganic & medicinal chemistry letters 13(22):4015-7, 2003 Nov 17 - Who cited this? | PubMed ID: 14592497 | Fulltext

Influence of acetylcholine levels on the binding of a SPECT nicotinic acetylcholine receptor ligand [123I]5-I-A-85380.

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Fujita M, Al-Tikriti MS, Tamagnan G, Zoghbi SS, Bozkurt A, Baldwin RM, and Innis RB

Synapse (New York, N.Y.) 48(3):116-22, 2003 Jun 1 - Who cited this? | PubMed ID: 12645036 | Fulltext

Rearrangement of a mesylate tropane intermediate in nucleophilic substitution reactions. Synthesis of aza-bicyclo[3.2.1]octane and aza-bicyclo[3.2.2]nonane ethers, imides, and amines.

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Ogier L, Turpin F, Baldwin RM, Riché F, Law H, Innis RB, and Tamagnan G

The Journal of organic chemistry 67(11):3637-42, 2002 May 31 - Who cited this? | PubMed ID: 12027674 | Fulltext

Synthesis, receptor potency, and selectivity of halogenated diphenylpiperidines as serotonin 5-HT2A ligands for PET or SPECT brain imaging.

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Fu X, Tan PZ, Kula NS, Baldessarini R, Tamagnan G, Innis RB, and Baldwin RM

Journal of medicinal chemistry 45(11):2319-24, 2002 May 23 - Who cited this? | PubMed ID: 12014970 | Fulltext

Whole-body biodistribution, radiation absorbed dose, and brain SPET imaging with [123i]5-i-A-85380 in healthy human subjects.

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Fujita M, Seibyl JP, Vaupel DB, Tamagnan G, Early M, Zoghbi SS, Baldwin RM, Horti AG, KoreN AO, Mukhin AG, Khan S, Bozkurt A, Kimes AS, London ED, and Innis RB

European journal of nuclear medicine and molecular imaging 29(2):183-90, 2002 Feb - Who cited this? | PubMed ID: 11926380 | Fulltext

Synthesis of cyclopentadienyltricarbonyl rhenium phenyltropanes by double ligand transfer: organometallic ligands for the dopamine transporter.

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Cesati RR, Tamagnan G, Baldwin RM, Zoghbi SS, Innis RB, Kula NS, Baldessarini RJ, and Katzenellenbogen JA

Bioconjugate chemistry 13(1):29-39, 2002 - Who cited this? | PubMed ID: 11792176 | Fulltext

Sex differences in [123I]beta-CIT SPECT measures of dopamine and serotonin transporter availability in healthy smokers and nonsmokers.

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Staley JK, Krishnan-Sarin S, Zoghbi S, Tamagnan G, Fujita M, Seibyl JP, Maciejewski PK, O'Malley S, and Innis RB

Synapse (New York, N.Y.) 41(4):275-84, 2001 Sep 15 - Who cited this? | PubMed ID: 11494398 | Fulltext

Measurement of plasma metabolites of (S)-5-[123I]iodo-3-(2-azetidinylmethoxy)pyridine (5-IA-85380), a nicotinic acetylcholine receptor imaging agent, in nonhuman primates.

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Zoghbi SS, Tamagnan G, Baldwin MF, Al-Tikriti MS, Amici L, Seibyl JP, and Innis RB

Nuclear medicine and biology 28(1):91-6, 2001 Jan - Who cited this? | PubMed ID: 11182569 | Fulltext

Measurement of alpha4beta2 nicotinic acetylcholine receptors with [123I]5-I-A-85380 SPECT.

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Fujita M, Tamagnan G, Zoghbi SS, Al-Tikriti MS, Baldwin RM, Seibyl JP, and Innis RB

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 41(9):1552-60, 2000 Sep - Who cited this? | PubMed ID: 10994738 | Fulltext

Synthesis and monoamine transporter affinity of 2beta-carbomethoxy-3beta-(2''-, 3''- or 4''-substituted) biphenyltropanes.

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Tamagnan G, Baldwin RM, Kula NS, Baldessarini RJ, and Innis RB

Bioorganic & medicinal chemistry letters 10(16):1783-5, 2000 Aug 21 - Who cited this? | PubMed ID: 10969967 | Fulltext

SPECT imaging with the D(4) receptor antagonist L-750,667 in nonhuman primate brain.

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Staley JK, Tamagnan G, Baldwin RM, Fujita M, Al Tikriti MS, Eshima L, Thornback J, Roe D, Lu L, Seibyl JP, and Innis RB

Nuclear medicine and biology 27(6):547-56, 2000 Aug - Who cited this? | PubMed ID: 11056368 | Fulltext

Cyclopentadienyltricarbonylrheniumbenzazepines: synthesis and binding affinity.

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Tamagnan G, Baldwin RM, Kula NS, Baldessarini RJ, and Innis RB

Bioorganic & medicinal chemistry letters 10(10):1113-5, 2000 May 15 - Who cited this? | PubMed ID: 10843230 | Fulltext

5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors.

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Mukhin AG, Gündisch D, Horti AG, Koren AO, Tamagnan G, Kimes AS, Chambers J, Vaupel DB, King SL, Picciotto MR, Innis RB, and London ED

Molecular pharmacology 57(3):642-9, 2000 Mar - Who cited this? | PubMed ID: 10692507 | Fulltext

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