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Papers authored by Suttles J

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Functional plasticity of macrophages: in situ reprogramming of tumor-associated macrophages.

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Stout RD, Watkins SK, and Suttles J

Journal of leukocyte biology 86(5):1105-9, 2009 Nov - Who cited this? | PubMed ID: 19605698 | Fulltext

Identification and characterization of a small molecule inhibitor of Fatty Acid binding proteins.

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Hertzel AV, Hellberg K, Reynolds JM, Kruse AC, Juhlmann BE, Smith AJ, Sanders MA, Ohlendorf DH, Suttles J, and Bernlohr DA

Journal of medicinal chemistry 52(19):6024-31, 2009 Oct 8 - Who cited this? | PubMed ID: 19754198 | Fulltext

Macrophage CD40 signaling: A pivotal regulator of disease protection and pathogenesis.

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Suttles J and Stout RD

Seminars in immunology 21(5):257-64, 2009 Oct - Who cited this? | PubMed ID: 19540774 | Fulltext

Rapid release of cytoplasmic IL-15 from tumor-associated macrophages is an initial and critical event in IL-12-initiated tumor regression.

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Watkins SK, Li B, Richardson KS, Head K, Egilmez NK, Zeng Q, Suttles J, and Stout RD

European journal of immunology 39(8):2126-35, 2009 Aug - Who cited this? | PubMed ID: 19609975 | Fulltext

Regulation of Th17 differentiation by epidermal fatty acid-binding protein.

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Li B, Reynolds JM, Stout RD, Bernlohr DA, and Suttles J

Journal of immunology (Baltimore, Md. : 1950) 182(12):7625-33, 2009 Jun 15 - Who cited this? | PubMed ID: 19494286 | Fulltext

Interaction of Adipocyte Fatty Acid-binding Protein (AFABP) and JAK2: AFABP/aP2 AS A REGULATOR OF JAK2 SIGNALING.

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Thompson BR, Mazurkiewicz-Muñoz AM, Suttles J, Carter-Su C, and Bernlohr DA

The Journal of biological chemistry 284(20):13473-80, 2009 May 15 - Who cited this? | PubMed ID: 19318353 | Fulltext

Inhibition of methionine adenosyltransferase II induces FasL expression, Fas-DISC formation and caspase-8-dependent apoptotic death in T leukemic cells.

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Jani TS, Gobejishvili L, Hote PT, Barve AS, Joshi-Barve S, Kharebava G, Suttles J, Chen T, McClain CJ, and Barve S

Cell research 19(3):358-69, 2009 Mar - Who cited this? | PubMed ID: 19048023 | Fulltext

Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype.

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Sag D, Carling D, Stout RD, and Suttles J

Journal of immunology (Baltimore, Md. : 1950) 181(12):8633-41, 2008 Dec 15 - Who cited this? | PubMed ID: 19050283 | Fulltext

Deficiency of fatty acid-binding proteins in mice confers protection from development of experimental autoimmune encephalomyelitis.

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Reynolds JM, Liu Q, Brittingham KC, Liu Y, Gruenthal M, Gorgun CZ, Hotamisligil GS, Stout RD, and Suttles J

Journal of immunology (Baltimore, Md. : 1950) 179(1):313-21, 2007 Jul 1 - Who cited this? | PubMed ID: 17579051 | Fulltext

Genetic susceptibility and caspase activation in mouse and human macrophages are distinct for Legionella longbeachae and L. pneumophila.

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Asare R, Santic M, Gobin I, Doric M, Suttles J, Graham JE, Price CD, and Abu Kwaik Y

Infection and immunity 75(4):1933-45, 2007 Apr - Who cited this? | PubMed ID: 17261610 | Fulltext

IL-12 rapidly alters the functional profile of tumor-associated and tumor-infiltrating macrophages in vitro and in vivo.

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Watkins SK, Egilmez NK, Suttles J, and Stout RD

Journal of immunology (Baltimore, Md. : 1950) 178(3):1357-62, 2007 Feb 1 - Who cited this? | PubMed ID: 17237382 | Fulltext

Anti-apoptotic signalling by the Dot/Icm secretion system of L. pneumophila.

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Abu-Zant A, Jones S, Asare R, Suttles J, Price C, Graham J, and Kwaik YA

Cellular microbiology 9(1):246-64, 2007 Jan - Who cited this? | PubMed ID: 16911566 | Fulltext

Generation of a multimeric form of CD40L with potent immunostimulatory activity using streptavidin as a chaperon.

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Kilinc MO, Mukundan L, Yolcu ES, Singh NP, Suttles J, and Shirwan H

Experimental and molecular pathology 80(3):252-61, 2006 Jun - Who cited this? | PubMed ID: 16487512 | Fulltext

Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis.

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Baumgartl J, Baudler S, Scherner M, Babaev V, Makowski L, Suttles J, McDuffie M, Tobe K, Kadowaki T, Fazio S, Kahn CR, Hotamisligil GS, Krone W, Linton M, and Brüning JC

Cell metabolism 3(4):247, 2006 Apr - Who cited this? | PubMed ID: 16581002 | Fulltext

The vaccinia virus N1L protein influences cytokine secretion in vitro after infection.

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Zhang Z, Abrahams MR, Hunt LA, Suttles J, Marshall W, Lahiri DK, and Kotwal GJ

Annals of the New York Academy of Sciences 1056:69-86, 2005 Nov - Who cited this? | PubMed ID: 16387678 | Fulltext

Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences.

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Stout RD, Jiang C, Matta B, Tietzel I, Watkins SK, and Suttles J

Journal of immunology (Baltimore, Md. : 1950) 175(1):342-9, 2005 Jul 1 - Who cited this? | PubMed ID: 15972667 | Fulltext

Immunosenescence and macrophage functional plasticity: dysregulation of macrophage function by age-associated microenvironmental changes.

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Stout RD and Suttles J

Immunological reviews 205:60-71, 2005 Jun - Who cited this? | PubMed ID: 15882345 | Fulltext

The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity. Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor gamma and IkappaB kinase activities.

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Makowski L, Brittingham KC, Reynolds JM, Suttles J, and Hotamisligil GS

The Journal of biological chemistry 280(13):12888-95, 2005 Apr 1 - Who cited this? | PubMed ID: 15684432 | Fulltext

TNF receptor-associated factor 6 is an essential mediator of CD40-activated proinflammatory pathways in monocytes and macrophages.

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Mukundan L, Bishop GA, Head KZ, Zhang L, Wahl LM, and Suttles J

Journal of immunology (Baltimore, Md. : 1950) 174(2):1081-90, 2005 Jan 15 - Who cited this? | PubMed ID: 15634933 | Fulltext

Functional plasticity of macrophages: reversible adaptation to changing microenvironments.

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Stout RD and Suttles J

Journal of leukocyte biology 76(3):509-13, 2004 Sep - Who cited this? | PubMed ID: 15218057 | Fulltext

CD40-mediated activation of vascular smooth muscle cell chemokine production through a Src-initiated, MAPK-dependent pathway.

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Mukundan L, Milhorn DM, Matta B, and Suttles J

Cellular signalling 16(3):375-84, 2004 Mar - Who cited this? | PubMed ID: 14687667 | Fulltext

Role of leukotriene B4 receptors in the development of atherosclerosis: potential mechanisms.

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Subbarao K, Jala VR, Mathis S, Suttles J, Zacharias W, Ahamed J, Ali H, Tseng MT, and Haribabu B

Arteriosclerosis, thrombosis, and vascular biology 24(2):369-75, 2004 Feb - Who cited this? | PubMed ID: 14656734 | Fulltext

Ectopic expression of protein-tyrosine kinase Bcr-Abl suppresses tumor necrosis factor (TNF)-induced NF-kappa B activation and IkappaBalpha phosphorylation. Relationship with down-regulation of TNF receptors.

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Mukhopadhyay A, Shishodia S, Suttles J, Brittingham K, Lamothe B, Nimmanapalli R, Bhalla KN, and Aggarwal BB

The Journal of biological chemistry 277(34):30622-8, 2002 Aug 23 - Who cited this? | PubMed ID: 12060665 | Fulltext

Genetic deletion of the tumor necrosis factor receptor p60 or p80 abrogates ligand-mediated activation of nuclear factor-kappa B and of mitogen-activated protein kinases in macrophages.

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Mukhopadhyay A, Suttles J, Stout RD, and Aggarwal BB

The Journal of biological chemistry 276(34):31906-12, 2001 Aug 24 - Who cited this? | PubMed ID: 11438547 | Fulltext

Panning T cells on vascular endothelial cell monolayers: a rapid method for enriching naive T cells.

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Hoellman JR, Suttles J, and Stout RD

Immunobiology 203(5):769-77, 2001 Aug - Who cited this? | PubMed ID: 11563676 | Fulltext

Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis.

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Makowski L, Boord JB, Maeda K, Babaev VR, Uysal KT, Morgan MA, Parker RA, Suttles J, Fazio S, Hotamisligil GS, and Linton MF

Nature medicine 7(6):699-705, 2001 Jun - Who cited this? | PubMed ID: 11385507 | Fulltext

LPS stimulation of TNF-receptor deficient macrophages: a differential role for TNF-alpha autocrine signaling in the induction of cytokine and nitric oxide production.

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Clemons-Miller AR, Cox GW, Suttles J, and Stout RD

Immunobiology 202(5):477-92, 2000 Nov - Who cited this? | PubMed ID: 11205376 | Fulltext

CD40 signaling of monocyte inflammatory cytokine synthesis through an ERK1/2-dependent pathway. A target of interleukin (il)-4 and il-10 anti-inflammatory action.

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Suttles J, Milhorn DM, Miller RW, Poe JC, Wahl LM, and Stout RD

The Journal of biological chemistry 274(9):5835-42, 1999 Feb 26 - Who cited this? | PubMed ID: 10026206 | Fulltext

Membrane potassium channels and human bladder tumor cells: II. Growth properties.

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Wondergem R, Cregan M, Strickler L, Miller R, and Suttles J

The Journal of membrane biology 161(3):257-62, 1998 Feb 1 - Who cited this? | PubMed ID: 9493131 | Fulltext

IL-4 and IL-10 modulation of CD40-mediated signaling of monocyte IL-1beta synthesis and rescue from apoptosis.

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Poe JC, Wagner DH, Miller RW, Stout RD, and Suttles J

Journal of immunology (Baltimore, Md. : 1950) 159(2):846-52, 1997 Jul 15 - Who cited this? | PubMed ID: 9218603 | Fulltext

T cell signaling of macrophage function in inflammatory disease.

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Stout RD and Suttles J

Frontiers in bioscience : a journal and virtual library 2:d197-206, 1997 May 1 - Who cited this? | PubMed ID: 9206987 | Fulltext

Multifunctional cytokine expression by human mast cells: regulation by T cell membrane contact and glucocorticoids.

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Krishnaswamy G, Lakshman T, Miller AR, Srikanth S, Hall K, Huang SK, Suttles J, Smith JK, and Stout R

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 17(3):167-76, 1997 Mar - Who cited this? | PubMed ID: 9085942 | Fulltext

Cytokine priming reduces dependence on TNF-R2 for TNF-alpha-mediated induction of macrophage nitric oxide generation.

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Miller AR, Suttles J, and Stout RD

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 16(12):1055-63, 1996 Dec - Who cited this? | PubMed ID: 8974009 | Fulltext

T cell rescue of monocytes from apoptosis: role of the CD40-CD40L interaction and requirement for CD40-mediated induction of protein tyrosine kinase activity.

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Suttles J, Evans M, Miller RW, Poe JC, Stout RD, and Wahl LM

Journal of leukocyte biology 60(5):651-7, 1996 Nov - Who cited this? | PubMed ID: 8929557 | Fulltext

The many roles of CD40 in cell-mediated inflammatory responses.

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Stout RD and Suttles J

Immunology today 17(10):487-92, 1996 Oct - Who cited this? | PubMed ID: 8908815 | Fulltext

Impaired T cell-mediated macrophage activation in CD40 ligand-deficient mice.

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Stout RD, Suttles J, Xu J, Grewal IS, and Flavell RA

Journal of immunology (Baltimore, Md. : 1950) 156(1):8-11, 1996 Jan 1 - Who cited this? | PubMed ID: 8598498 | Fulltext

Indomethacin does not alter natural killer cell response to 2.5 h of running.

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Nieman DC, Ahle JC, Henson DA, Warren BJ, Suttles J, Davis JM, Buckley KS, Simandle S, Butterworth DE, and Fagoaga OR

Journal of applied physiology (Bethesda, Md. : 1985) 79(3):748-55, 1995 Sep - Who cited this? | PubMed ID: 8567513 | Fulltext

Lymphocyte proliferative response to 2.5 hours of running.

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Nieman DC, Simandle S, Henson DA, Warren BJ, Suttles J, Davis JM, Buckley KS, Ahle JC, Butterworth DE, and Fagoaga OR

International journal of sports medicine 16(6):404-9, 1995 Aug - Who cited this? | PubMed ID: 7591393 | Fulltext

The acute immune response to exhaustive resistance exercise.

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Nieman DC, Henson DA, Sampson CS, Herring JL, Suttles J, Conley M, Stone MH, Butterworth DE, and Davis JM

International journal of sports medicine 16(5):322-8, 1995 Jul - Who cited this? | PubMed ID: 7558530 | Fulltext

Immune function in athletes versus nonathletes.

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Nieman DC, Brendle D, Henson DA, Suttles J, Cook VD, Warren BJ, Butterworth DE, Fagoaga OR, and Nehlsen-Cannarella SL

International journal of sports medicine 16(5):329-33, 1995 Jul - Who cited this? | PubMed ID: 7558531 | Fulltext

Moderate exercise training and natural killer cell cytotoxic activity in breast cancer patients.

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Nieman DC, Cook VD, Henson DA, Suttles J, Rejeski WJ, Ribisl PM, Fagoaga OR, and Nehlsen-Cannarella SL

International journal of sports medicine 16(5):334-7, 1995 Jul - Who cited this? | PubMed ID: 7558532 | Fulltext

Immune function in marathon runners versus sedentary controls.

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Nieman DC, Buckley KS, Henson DA, Warren BJ, Suttles J, Ahle JC, Simandle S, Fagoaga OR, and Nehlsen-Cannarella SL

Medicine and science in sports and exercise 27(7):986-92, 1995 Jul - Who cited this? | PubMed ID: 7564985 | Fulltext

T cell--vascular smooth muscle cell interactions: antigen-specific activation and cell cycle blockade of T helper clones by cloned vascular smooth muscle cells.

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Suttles J, Miller RW, and Moyer CF

Experimental cell research 218(1):331-8, 1995 May - Who cited this? | PubMed ID: 7737369 | Fulltext

Role of the CD40-CD40 ligand interaction in CD4+ T cell contact-dependent activation of monocyte interleukin-1 synthesis.

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Wagner DH, Stout RD, and Suttles J

European journal of immunology 24(12):3148-54, 1994 Dec - Who cited this? | PubMed ID: 7528671 | Fulltext

T cells which do not express membrane tumor necrosis factor-alpha activate macrophage effector function by cell contact-dependent signaling of macrophage tumor necrosis factor-alpha production.

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Suttles J, Miller RW, Tao X, and Stout RD

European journal of immunology 24(8):1736-42, 1994 Aug - Who cited this? | PubMed ID: 8056032 | Fulltext

T cell-macrophage cognate interaction in the activation of macrophage effector function by Th2 cells.

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Stout RD and Suttles J

Journal of immunology (Baltimore, Md. : 1950) 150(12):5330-7, 1993 Jun 15 - Who cited this? | PubMed ID: 8515061 | Fulltext

T cells bearing the CD44hi "memory" phenotype display characteristics of activated cells in G1 stage of cell cycle.

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Stout RD and Suttles J

Cellular immunology 141(2):433-43, 1992 May - Who cited this? | PubMed ID: 1533571 | Fulltext

Evidence for involvement of TNF-alpha in the induction phase and IFN-beta in the effector phase of antiproliferative activity of splenic macrophages.

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Stout RD and Suttles J

Cellular immunology 139(2):363-74, 1992 Feb - Who cited this? | PubMed ID: 1733508 | Fulltext

Costimulatory function of APCs.

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Suttles J

Immunology today 11(9):304, 1990 Sep - Who cited this? | PubMed ID: 2206274 | Fulltext

Detection of IL-1 alpha and IL-1 beta in the supernatants of paraformaldehyde-treated human monocytes. Evidence against a membrane form of IL-1.

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Suttles J, Carruth LM, and Mizel SB

Journal of immunology (Baltimore, Md. : 1950) 144(1):170-4, 1990 Jan 1 - Who cited this? | PubMed ID: 2295789 | Fulltext

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