Papers authored by Sukhova GK

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Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation.
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Sun J, Zhang J, Lindholt JS, Sukhova GK, Liu J, He A, Abrink M, Pejler G, Stevens RL, Thompson RW, Ennis TL, Gurish MF, Libby P, and Shi GP
Circulation 120(11):973-82, 2009 Sep 15 - Who cited this? | PubMed ID: 19720934 | Fulltext
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Myeloid-related protein-8/14 is critical for the biological response to vascular injury.
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Croce K, Gao H, Wang Y, Mooroka T, Sakuma M, Shi C, Sukhova GK, Packard RR, Hogg N, Libby P, and Simon DI
Circulation 120(5):427-36, 2009 Aug 4 - Who cited this? | PubMed ID: 19620505 | Fulltext
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Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice.
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Liu J, Divoux A, Sun J, Zhang J, Clément K, Glickman JN, Sukhova GK, Wolters PJ, Du J, Gorgun CZ, Doria A, Libby P, Blumberg RS, Kahn BB, Hotamisligil GS, and Shi GP
Nature medicine 15(8):940-5, 2009 Aug - Who cited this? | PubMed ID: 19633655 | Fulltext
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Complement Regulator CD59 Protects Against Atherosclerosis by Restricting the Formation of Complement Membrane Attack Complex.
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Wu G, Hu W, Shahsafaei A, Song W, Dobarro M, Sukhova GK, Bronson RR, Shi GP, Rother RP, Halperin JA, and Qin X
Circulation research 104(4):550-8, 2009 Feb 27 - Who cited this? | PubMed ID: 19131645 | Fulltext
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Genetically programmed biases in Th1 and th2 immune responses modulate atherogenesis.
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Schulte S, Sukhova GK, and Libby P
The American journal of pathology 172(6):1500, 2008 Jun - Who cited this? | PubMed ID: 18467709 | Fulltext
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Matrix metalloproteinase-14 deficiency in bone marrow-derived cells promotes collagen accumulation in mouse atherosclerotic plaques.
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Schneider F, Sukhova GK, Aikawa M, Canner J, Gerdes N, Tang SM, Shi GP, Apte SS, and Libby P
Circulation 117(7):931-9, 2008 Feb 19 - Who cited this? | PubMed ID: 18250269 | Fulltext
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Adiponectin inhibits the production of CXC receptor 3 chemokine ligands in macrophages and reduces T-lymphocyte recruitment in atherogenesis.
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Okamoto Y, Folco EJ, Minami M, Wara AK, Feinberg MW, Sukhova GK, Colvin RA, Kihara S, Funahashi T, Luster AD, and Libby P
Circulation research 102(2):218, 2008 Feb 1 - Who cited this? | PubMed ID: 17991878 | Fulltext
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Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice.
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Sun J, Sukhova GK, Yang M, Wolters PJ, MacFarlane LA, Libby P, Sun C, Zhang Y, Liu J, Ennis TL, Knispel R, Xiong W, Thompson RW, Baxter BT, and Shi GP
The Journal of clinical investigation 117(11):3359, 2007 Nov - Who cited this? | PubMed ID: 17932568 | Fulltext
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Cathepsin L activity controls adipogenesis and glucose tolerance.
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Yang M, Zhang Y, Pan J, Sun J, Liu J, Libby P, Sukhova GK, Doria A, Katunuma N, Peroni OD, Guerre-Millo M, Kahn BB, Clement K, and Shi GP
Nature cell biology 9(8):970-7, 2007 Aug - Who cited this? | PubMed ID: 17643114 | Fulltext
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Mast cells promote atherosclerosis by releasing proinflammatory cytokines.
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Sun J, Sukhova GK, Wolters PJ, Yang M, Kitamoto S, Libby P, MacFarlane LA, Mallen-St Clair J, and Shi GP
Nature medicine 13(6):719-24, 2007 Jun - Who cited this? | PubMed ID: 17546038 | Fulltext
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Deletion of the phosphoinositide 3-kinase p110gamma gene attenuates murine atherosclerosis.
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Chang JD, Sukhova GK, Libby P, Schvartz E, Lichtenstein AH, Field SJ, Kennedy C, Madhavarapu S, Luo J, Wu D, and Cantley LC
Proceedings of the National Academy of Sciences of the United States of America 104(19):8077, 2007 May 8 - Who cited this? | PubMed ID: 17483449 | Fulltext
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Cathepsin L deficiency reduces diet-induced atherosclerosis in low-density lipoprotein receptor-knockout mice.
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Kitamoto S, Sukhova GK, Sun J, Yang M, Libby P, Love V, Duramad P, Sun C, Zhang Y, Yang X, Peters C, and Shi GP
Circulation 115(15):2065, 2007 Apr 17 - Who cited this? | PubMed ID: 17404153 | Fulltext
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Do cathepsins play a role in abdominal aortic aneurysm pathogenesis?.
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Sukhova GK and Shi GP
Annals of the New York Academy of Sciences 1085:161-9, 2006 Nov - Who cited this? | PubMed ID: 17182932 | Fulltext
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A novel prostaglandin E receptor 4-associated protein participates in antiinflammatory signaling.
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Takayama K, Sukhova GK, Chin MT, and Libby P
Circulation research 98(4):499, 2006 Mar 3 - Who cited this? | PubMed ID: 16424369 | Fulltext
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Cathepsin L expression and regulation in human abdominal aortic aneurysm, atherosclerosis, and vascular cells.
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Liu J, Sukhova GK, Yang JT, Sun J, Ma L, Ren A, Xu WH, Fu H, Dolganov GM, Hu C, Libby P, and Shi GP
Atherosclerosis 184(2):302-11, 2006 Feb - Who cited this? | PubMed ID: 15982660 | Fulltext
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Angiotensin type 2 receptor is expressed in murine atherosclerotic lesions and modulates lesion evolution.
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Sales VL, Sukhova GK, Lopez-Ilasaca MA, Libby P, Dzau VJ, and Pratt RE
Circulation 112(21):3328-36, 2005 Nov 22 - Who cited this? | PubMed ID: 16286588 | Fulltext
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Cystatin C deficiency increases elastic lamina degradation and aortic dilatation in apolipoprotein E-null mice.
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Sukhova GK, Wang B, Libby P, Pan JH, Zhang Y, Grubb A, Fang K, Chapman HA, and Shi GP
Circulation research 96(3):368-75, 2005 Feb 18 - Who cited this? | PubMed ID: 15653570 | Fulltext
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Enhanced expression of CD44 variants in human atheroma and abdominal aortic aneurysm: possible role for a feedback loop in endothelial cells.
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Krettek A, Sukhova GK, Schönbeck U, and Libby P
The American journal of pathology 165(5):1571-81, 2004 Nov - Who cited this? | PubMed ID: 15509527 | Fulltext
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Lysosomal cysteine proteases in atherosclerosis.
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Liu J, Sukhova GK, Sun JS, Xu WH, Libby P, and Shi GP
Arteriosclerosis, thrombosis, and vascular biology 24(8):1359-66, 2004 Aug - Who cited this? | PubMed ID: 15178558 | Fulltext
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Macrophage migration inhibitory factor deficiency impairs atherosclerosis in low-density lipoprotein receptor-deficient mice.
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Pan JH, Sukhova GK, Yang JT, Wang B, Xie T, Fu H, Zhang Y, Satoskar AR, David JR, Metz CN, Bucala R, Fang K, Simon DI, Chapman HA, Libby P, and Shi GP
Circulation 109(25):3149-53, 2004 Jun 29 - Who cited this? | PubMed ID: 15197138 | Fulltext
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Neutrophil elastase in human atherosclerotic plaques: production by macrophages.
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Dollery CM, Owen CA, Sukhova GK, Krettek A, Shapiro SD, and Libby P
Circulation 107(22):2829-36, 2003 Jun 10 - Who cited this? | PubMed ID: 12771009 | Fulltext
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Elastogenesis in human arterial disease: a role for macrophages in disordered elastin synthesis.
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Krettek A, Sukhova GK, and Libby P
Arteriosclerosis, thrombosis, and vascular biology 23(4):582-7, 2003 Apr 1 - Who cited this? | PubMed ID: 12615674 | Fulltext
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Deficiency of the cysteine protease cathepsin S impairs microvessel growth.
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Shi GP, Sukhova GK, Kuzuya M, Ye Q, Du J, Zhang Y, Pan JH, Lu ML, Cheng XW, Iguchi A, Perrey S, Lee AM, Chapman HA, and Libby P
Circulation research 92(5):493-500, 2003 Mar 21 - Who cited this? | PubMed ID: 12600886 | Fulltext
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Macrophage migration inhibitory factor is associated with aneurysmal expansion.
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Pan JH, Lindholt JS, Sukhova GK, Baugh JA, Henneberg EW, Bucala R, Donnelly SC, Libby P, Metz C, and Shi GP
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 37(3):628, 2003 Mar - Who cited this? | PubMed ID: 12618703 | Fulltext
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Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice.
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Sukhova GK, Zhang Y, Pan JH, Wada Y, Yamamoto T, Naito M, Kodama T, Tsimikas S, Witztum JL, Lu ML, Sakara Y, Chin MT, Libby P, and Shi GP
The Journal of clinical investigation 111(6):897-906, 2003 Mar - Who cited this? | PubMed ID: 12639996 | Fulltext
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Prostaglandin E2 suppresses chemokine production in human macrophages through the EP4 receptor.
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Takayama K, García-Cardena G, Sukhova GK, Comander J, Gimbrone MA, and Libby P
The Journal of biological chemistry 277(46):44147, 2002 Nov 15 - Who cited this? | PubMed ID: 12215436 | Fulltext
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Statins reduce inflammation in atheroma of nonhuman primates independent of effects on serum cholesterol.
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Sukhova GK, Williams JK, and Libby P
Arteriosclerosis, thrombosis, and vascular biology 22(9):1452-8, 2002 Sep 1 - Who cited this? | PubMed ID: 12231565 | Fulltext
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T(H)2 predominant immune responses prevail in human abdominal aortic aneurysm.
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Schönbeck U, Sukhova GK, Gerdes N, and Libby P
The American journal of pathology 161(2):499-506, 2002 Aug - Who cited this? | PubMed ID: 12163375 | Fulltext
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Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for atherogenesis.
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Gerdes N, Sukhova GK, Libby P, Reynolds RS, Young JL, and Schönbeck U
The Journal of experimental medicine 195(2):245-57, 2002 Jan 21 - Who cited this? | PubMed ID: 11805151 | Fulltext
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Influence of Helicobacter pylori infection during atherogenesis in vivo in mice.
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Mach F, Sukhova GK, Michetti M, Libby P, and Michetti P
Circulation research 90(1):E1-4, 2002 Jan 11 - Who cited this? | PubMed ID: 11786527 | Fulltext
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Expression of neutrophil collagenase (matrix metalloproteinase-8) in human atheroma: a novel collagenolytic pathway suggested by transcriptional profiling.
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Herman MP, Sukhova GK, Libby P, Gerdes N, Tang N, Horton DB, Kilbride M, Breitbart RE, Chun M, and Schönbeck U
Circulation 104(16):1899-904, 2001 Oct 16 - Who cited this? | PubMed ID: 11602491 | Fulltext
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Pathogenesis of abdominal aortic aneurysms: a multidisciplinary research program supported by the National Heart, Lung, and Blood Institute.
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Wassef M, Baxter BT, Chisholm RL, Dalman RL, Fillinger MF, Heinecke J, Humphrey JD, Kuivaniemi H, Parks WC, Pearce WH, Platsoucas CD, Sukhova GK, Thompson RW, Tilson MD, and Zarins CK
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 34(4):730-8, 2001 Oct - Who cited this? | PubMed ID: 11668331 | Fulltext
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Tissue factor pathway inhibitor-2 is a novel inhibitor of matrix metalloproteinases with implications for atherosclerosis.
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Herman MP, Sukhova GK, Kisiel W, Foster D, Kehry MR, Libby P, and Schönbeck U
The Journal of clinical investigation 107(9):1117-26, 2001 May - Who cited this? | PubMed ID: 11342575 | Fulltext
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Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes.
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Sugiyama S, Okada Y, Sukhova GK, Virmani R, Heinecke JW, and Libby P
The American journal of pathology 158(3):879-91, 2001 Mar - Who cited this? | PubMed ID: 11238037 | Fulltext
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Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice.
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Schönbeck U, Sukhova GK, Shimizu K, Mach F, and Libby P
Proceedings of the National Academy of Sciences of the United States of America 97(13):7458-63, 2000 Jun 20 - Who cited this? | PubMed ID: 10861012 | Fulltext
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The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells.
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Young JL, Sukhova GK, Foster D, Kisiel W, Libby P, and Schönbeck U
The Journal of experimental medicine 191(9):1535-44, 2000 May 1 - Who cited this? | PubMed ID: 10790428 | Fulltext
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The stromal cell-derived factor-1 chemokine is a potent platelet agonist highly expressed in atherosclerotic plaques.
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Abi-Younes S, Sauty A, Mach F, Sukhova GK, Libby P, and Luster AD
Circulation research 86(2):131-8, 2000 Feb 4 - Who cited this? | PubMed ID: 10666407 | Fulltext
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CD40 ligation induces tissue factor expression in human vascular smooth muscle cells.
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Schönbeck U, Mach F, Sukhova GK, Herman M, Graber P, Kehry MR, and Libby P
The American journal of pathology 156(1):7-14, 2000 Jan - Who cited this? | PubMed ID: 10623647 | Fulltext
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Cystatin C deficiency in human atherosclerosis and aortic aneurysms.
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Shi GP, Sukhova GK, Grubb A, Ducharme A, Rhode LH, Lee RT, Ridker PM, Libby P, and Chapman HA
The Journal of clinical investigation 104(9):1191-7, 1999 Nov - Who cited this? | PubMed ID: 10545518 | Fulltext
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Augmented expression of cyclooxygenase-2 in human atherosclerotic lesions.
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Schönbeck U, Sukhova GK, Graber P, Coulter S, and Libby P
The American journal of pathology 155(4):1281-91, 1999 Oct - Who cited this? | PubMed ID: 10514410 | Fulltext
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Differential expression of three T lymphocyte-activating CXC chemokines by human atheroma-associated cells.
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Mach F, Sauty A, Iarossi AS, Sukhova GK, Neote K, Libby P, and Luster AD
The Journal of clinical investigation 104(8):1041-50, 1999 Oct - Who cited this? | PubMed ID: 10525042 | Fulltext
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CD1 expression in human atherosclerosis. A potential mechanism for T cell activation by foam cells.
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Melián A, Geng YJ, Sukhova GK, Libby P, and Porcelli SA
The American journal of pathology 155(3):775-86, 1999 Sep - Who cited this? | PubMed ID: 10487835 | Fulltext
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PPARalpha activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells.
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Marx N, Sukhova GK, Collins T, Libby P, and Plutzky J
Circulation 99(24):3125-31, 1999 Jun 22 - Who cited this? | PubMed ID: 10377075 | Fulltext
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Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques.
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Sukhova GK, Schönbeck U, Rabkin E, Schoen FJ, Poole AR, Billinghurst RC, and Libby P
Circulation 99(19):2503-9, 1999 May 18 - Who cited this? | PubMed ID: 10330380 | Fulltext
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Expression of stromelysin-3 in atherosclerotic lesions: regulation via CD40-CD40 ligand signaling in vitro and in vivo.
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Schönbeck U, Mach F, Sukhova GK, Atkinson E, Levesque E, Herman M, Graber P, Basset P, and Libby P
The Journal of experimental medicine 189(5):843-53, 1999 Mar 1 - Who cited this? | PubMed ID: 10049948 | Fulltext
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PPARgamma activation in human endothelial cells increases plasminogen activator inhibitor type-1 expression: PPARgamma as a potential mediator in vascular disease.
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Marx N, Bourcier T, Sukhova GK, Libby P, and Plutzky J
Arteriosclerosis, thrombosis, and vascular biology 19(3):546-51, 1999 Mar - Who cited this? | PubMed ID: 10073956 | Fulltext
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Death of smooth muscle cells and expression of mediators of apoptosis by T lymphocytes in human abdominal aortic aneurysms.
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Henderson EL, Geng YJ, Sukhova GK, Whittemore AD, Knox J, and Libby P
Circulation 99(1):96-104, 1999 - Who cited this? | PubMed ID: 9884385 | Fulltext
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Expression of tissue inhibitor of metalloproteinases-3 in human atheroma and regulation in lesion-associated cells: a potential protective mechanism in plaque stability.
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Fabunmi RP, Sukhova GK, Sugiyama S, and Libby P
Circulation research 83(3):270-8, 1998 Aug 10 - Who cited this? | PubMed ID: 9710119 | Fulltext
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Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells.
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Sukhova GK, Shi GP, Simon DI, Chapman HA, and Libby P
The Journal of clinical investigation 102(3):576-83, 1998 Aug 1 - Who cited this? | PubMed ID: 9691094 | Fulltext
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Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice.
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Gu L, Okada Y, Clinton SK, Gerard C, Sukhova GK, Libby P, and Rollins BJ
Molecular cell 2(2):275-81, 1998 Aug - Who cited this? | PubMed ID: 9734366 | Fulltext
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