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Papers authored by Sugamura K

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Significance of a multiple biomarkers strategy including endothelial dysfunction to improve risk stratification for cardiovascular events in patients at high risk for coronary heart disease.

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Nozaki T, Sugiyama S, Koga H, Sugamura K, Ohba K, Matsuzawa Y, Sumida H, Matsui K, Jinnouchi H, and Ogawa H

Journal of the American College of Cardiology 54(7):601-8, 2009 Aug 11 - Who cited this? | PubMed ID: 19660689 | Fulltext

The analysis of the functions of human B and T cells in humanized NOD/shi-scid/{gamma}cnull (NOG) mice (hu-HSC NOG mice).

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Watanabe Y, Takahashi T, Okajima A, Shiokawa M, Ishii N, Katano I, Ito R, Ito M, Minegishi M, Minegishi N, Tsuchiya S, and Sugamura K

International immunology 21(7):843-58, 2009 Jul - Who cited this? | PubMed ID: 19515798 | Fulltext

Procyanidins and butanol extract of Cinnamomi Cortex inhibit SARS-CoV infection.

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Zhuang M, Jiang H, Suzuki Y, Li X, Xiao P, Tanaka T, Ling H, Yang B, Saitoh H, Zhang L, Qin C, Sugamura K, and Hattori T

Antiviral research 82(1):73-81, 2009 Apr - Who cited this? | PubMed ID: 19428598 | Fulltext

Significant association between score of periodontal disease and coronary artery disease.

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Oe Y, Soejima H, Nakayama H, Fukunaga T, Sugamura K, Kawano H, Sugiyama S, Matsuo K, Shinohara M, Izumi Y, and Ogawa H

Heart and vessels 24(2):103-7, 2009 Mar - Who cited this? | PubMed ID: 19337793 | Fulltext

Activated endocannabinoid system in coronary artery disease and antiinflammatory effects of cannabinoid 1 receptor blockade on macrophages.

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Sugamura K, Sugiyama S, Nozaki T, Matsuzawa Y, Izumiya Y, Miyata K, Nakayama M, Kaikita K, Obata T, Takeya M, and Ogawa H

Circulation 119(1):28-36, 2009 Jan 6 - Who cited this? | PubMed ID: 19103987 | Fulltext

Generation of a syngeneic mouse model to study the intraperitoneal dissemination of ovarian cancer with in vivo luciferase imaging.

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Toyoshima M, Tanaka Y, Matumoto M, Yamazaki M, Nagase S, Sugamura K, and Yaegashi N

Luminescence : the journal of biological and chemical luminescence 24(5):324-31, 2009 - Who cited this? | PubMed ID: 19711487 | Fulltext

Loss of hrs in the central nervous system causes accumulation of ubiquitinated proteins and neurodegeneration.

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Tamai K, Toyoshima M, Tanaka N, Yamamoto N, Owada Y, Kiyonari H, Murata K, Ueno Y, Ono M, Shimosegawa T, Yaegashi N, Watanabe M, and Sugamura K

The American journal of pathology 173(6):1806-17, 2008 Dec - Who cited this? | PubMed ID: 19008375 | Fulltext

OX40 Costimulatory Signals Potentiate the Memory Commitment of Effector CD8+ T Cells.

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Mousavi SF, Soroosh P, Takahashi T, Yoshikai Y, Shen H, Lefrançois L, Borst J, Sugamura K, and Ishii N

Journal of immunology (Baltimore, Md. : 1950) 181(9):5990-6001, 2008 Nov 1 - Who cited this? | PubMed ID: 18941188 | Fulltext

Statin Ameliorates Hypoxia-Induced Pulmonary Hypertension Associated with Down-regulated Stromal Cell-Derived Factor-1.

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Satoh K, Fukumoto Y, Nakano M, Sugimura K, Nawata J, Demachi J, Karibe A, Kagaya Y, Ishii N, Sugamura K, and Shimokawa H

Cardiovascular research, 2008 Sep 8 - Who cited this? | PubMed ID: 18779230 | Fulltext

Synergism of CPT-11 and Apo2L/TRAIL against Two Differentially Sensitive Human Colon Tumor Xenografts.

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Sugamura K, Gibbs JF, Belicha-Villanueva A, Andrews C, Repasky EA, and Hylander BL

Oncology 74(3-4):188, 2008 Aug 20 - Who cited this? | PubMed ID: 18714167 | Fulltext

Co-inhibitory roles for glucocorticoid-induced TNF receptor in CD1d-dependent natural killer T cells.

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Chen S, Ndhlovu LC, Takahashi T, Takeda K, Ikarashi Y, Kikuchi T, Murata K, Pandolfi PP, Riccardi C, Ono M, Sugamura K, and Ishii N

European journal of immunology 38(8):2229, 2008 Aug - Who cited this? | PubMed ID: 18624295 | Fulltext

Endosomal sorting complex required for transport proteins in cancer pathogenesis, vesicular transport, and non-endosomal functions.

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Tanaka N, Kyuuma M, and Sugamura K

Cancer science 99(7):1293-303, 2008 Jul - Who cited this? | PubMed ID: 18429951 | Fulltext

Benefit of adding pioglitazone to successful statin therapy in nondiabetic patients with coronary artery disease.

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Sugamura K, Sugiyama S, Matsuzawa Y, Nozaki T, Horibata Y, and Ogawa H

Circulation journal : official journal of the Japanese Circulation Society 72(7):1193-7, 2008 Jul - Who cited this? | PubMed ID: 18577834 | Fulltext

c-Cbl-dependent Monoubiquitination and Lysosomal Degradation of gp130.

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Tanaka Y, Tanaka N, Saeki Y, Tanaka K, Murakami M, Hirano T, Ishii N, and Sugamura K

Molecular and cellular biology, 2008 Jun 2 - Who cited this? | PubMed ID: 18519587 | Fulltext

Ubiquitin-independent binding of Hrs mediates endosomal sorting of the interleukin-2 receptor {beta}-chain.

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Yamashita Y, Kojima K, Tsukahara T, Agawa H, Yamada K, Amano Y, Kurotori N, Tanaka N, Sugamura K, and Takeshita T

Journal of cell science 121(Pt 10):1727-38, 2008 May 15 - Who cited this? | PubMed ID: 18445679 | Fulltext

Mannose-Binding Lectin (MBL)-Associated Serine Protease (MASP)-1 Contributes to Activation of the Lectin Complement Pathway.

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Takahashi M, Iwaki D, Kanno K, Ishida Y, Xiong J, Matsushita M, Endo Y, Miura S, Ishii N, Sugamura K, and Fujita T

Journal of immunology (Baltimore, Md. : 1950) 180(9):6132-8, 2008 May 1 - Who cited this? | PubMed ID: 18424734 | Fulltext

Elevated mature macrophage expression of human ABHD2 gene in vulnerable plaque.

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Miyata K, Nakayama M, Mizuta S, Hokimoto S, Sugamura K, Oshima S, Oike Y, Sugiyama S, Ogawa H, and Yamamura K

Biochemical and biophysical research communications 365(2):207-13, 2008 Jan 11 - Who cited this? | PubMed ID: 17980156 | Fulltext

OX40 ligand expressed by DCs costimulates NKT and CD4+ Th cell antitumor immunity in mice.

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Zaini J, Andarini S, Tahara M, Saijo Y, Ishii N, Kawakami K, Taniguchi M, Sugamura K, Nukiwa T, and Kikuchi T

The Journal of clinical investigation 117(11):3330-8, 2007 Nov - Who cited this? | PubMed ID: 17975668 | Fulltext

Differential requirements for OX40 signals on generation of effector and central memory CD4+ T cells.

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Soroosh P, Ine S, Sugamura K, and Ishii N

Journal of immunology (Baltimore, Md. : 1950) 179(8):5014-23, 2007 Oct 15 - Who cited this? | PubMed ID: 17911586 | Fulltext

Human CD4+ central and effector memory T cells produce IL-21: effect on cytokine-driven proliferation of CD4+ T cell subsets.

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Onoda T, Rahman M, Nara H, Araki A, Makabe K, Tsumoto K, Kumagai I, Kudo T, Ishii N, Tanaka N, Sugamura K, Hayasaka K, and Asao H

International immunology 19(10):1191-9, 2007 Oct - Who cited this? | PubMed ID: 17698559 | Fulltext

Pravastatin improved glucose metabolism associated with increasing plasma adiponectin in patients with impaired glucose tolerance and coronary artery disease.

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Sugiyama S, Fukushima H, Kugiyama K, Maruyoshi H, Kojima S, Funahashi T, Sakamoto T, Horibata Y, Watanabe K, Koga H, Sugamura K, Otsuka F, Shimomura I, and Ogawa H

Atherosclerosis 194(2):e43-51, 2007 Oct - Who cited this? | PubMed ID: 17112529 | Fulltext

Role of Hrs in maturation of autophagosomes in mammalian cells.

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Tamai K, Tanaka N, Nara A, Yamamoto A, Nakagawa I, Yoshimori T, Ueno Y, Shimosegawa T, and Sugamura K

Biochemical and biophysical research communications 360(4):721, 2007 Sep 7 - Who cited this? | PubMed ID: 17624298 | Fulltext

Clathrin-dependent entry of severe acute respiratory syndrome coronavirus into target cells expressing ACE2 with the cytoplasmic tail deleted.

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Inoue Y, Tanaka N, Tanaka Y, Inoue S, Morita K, Zhuang M, Hattori T, and Sugamura K

Journal of virology 81(16):8722-9, 2007 Aug - Who cited this? | PubMed ID: 17522231 | Fulltext

Relation between CD4+ T-cell activation and severity of chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.

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Fukunaga T, Soejima H, Irie A, Sugamura K, Oe Y, Tanaka T, Nagayoshi Y, Kaikita K, Sugiyama S, Yoshimura M, Nishimura Y, and Ogawa H

The American journal of cardiology 100(3):483-8, 2007 Aug 1 - Who cited this? | PubMed ID: 17659933 | Fulltext

Inhibition of tumor growth and metastasis by depletion of vesicular sorting protein Hrs: its regulatory role on E-cadherin and beta-catenin.

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Toyoshima M, Tanaka N, Aoki J, Tanaka Y, Murata K, Kyuuma M, Kobayashi H, Ishii N, Yaegashi N, and Sugamura K

Cancer research 67(11):5162-71, 2007 Jun 1 - Who cited this? | PubMed ID: 17545595 | Fulltext

Expression of interferon-gamma and interleukin-4 production in CD4+ T cells in patients with chronic heart failure.

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Fukunaga T, Soejima H, Irie A, Sugamura K, Oe Y, Tanaka T, Kojima S, Sakamoto T, Yoshimura M, Nishimura Y, and Ogawa H

Heart and vessels 22(3):178-83, 2007 May - Who cited this? | PubMed ID: 17533522 | Fulltext

Important role of erythropoietin receptor to promote VEGF expression and angiogenesis in peripheral ischemia in mice.

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Nakano M, Satoh K, Fukumoto Y, Ito Y, Kagaya Y, Ishii N, Sugamura K, and Shimokawa H

Circulation research 100(5):662-9, 2007 Mar 16 - Who cited this? | PubMed ID: 17293480 | Fulltext

AMSH, an ESCRT-III associated enzyme, deubiquitinates cargo on MVB/late endosomes.

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Kyuuma M, Kikuchi K, Kojima K, Sugawara Y, Sato M, Mano N, Goto J, Takeshita T, Yamamoto A, Sugamura K, and Tanaka N

Cell structure and function 31(2):159-72, 2007 - Who cited this? | PubMed ID: 17159328 | Fulltext

Fulminant myocarditis survivor after 56 hours of non-responsive cardiac arrest successfully returned to normal life by cardiac resynchronization therapy: a case report.

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Sugamura K, Sugiyama S, Kawano H, Horio E, Ono S, Kojima S, Kaikita K, Sagishima K, Sakamoto T, Yoshimura M, Kinoshita Y, and Ogawa H

Journal of cardiology 48(6):345-52, 2006 Dec - Who cited this? | PubMed ID: 17243629 | Fulltext

Prostaglandin D2 plays an essential role in chronic allergic inflammation of the skin via CRTH2 receptor.

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Satoh T, Moroi R, Aritake K, Urade Y, Kanai Y, Sumi K, Yokozeki H, Hirai H, Nagata K, Hara T, Utsuyama M, Hirokawa K, Sugamura K, Nishioka K, and Nakamura M

Journal of immunology (Baltimore, Md. : 1950) 177(4):2621, 2006 Aug 15 - Who cited this? | PubMed ID: 16888024 | Fulltext

Clinical manifestations and outcomes of parvovirus B19 infection during pregnancy in Japan.

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Chisaka H, Ito K, Niikura H, Sugawara J, Takano T, Murakami T, Terada Y, Okamura K, Shiroishi H, Sugamura K, and Yaegashi N

The Tohoku journal of experimental medicine 209(4):277-83, 2006 Aug - Who cited this? | PubMed ID: 16864949 | Fulltext

Grb2 and Gads exhibit different interactions with CD28 and play distinct roles in CD28-mediated costimulation.

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Watanabe R, Harada Y, Takeda K, Takahashi J, Ohnuki K, Ogawa S, Ohgai D, Kaibara N, Koiwai O, Tanabe K, Toma H, Sugamura K, and Abe R

Journal of immunology (Baltimore, Md. : 1950) 177(2):1085-91, 2006 Jul 15 - Who cited this? | PubMed ID: 16818765 | Fulltext

Elevated plasma osteopontin levels were associated with osteopontin expression of CD4+ T cells in patients with unstable angina.

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Soejima H, Irie A, Fukunaga T, Sugamura K, Kojima S, Sakamoto T, Yoshimura M, Kishikawa H, Nishimura Y, and Ogawa H

Circulation journal : official journal of the Japanese Circulation Society 70(7):851-6, 2006 Jul - Who cited this? | PubMed ID: 16799237 | Fulltext

Survival of parvovirus B19-infected cells by cellular autophagy.

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Nakashima A, Tanaka N, Tamai K, Kyuuma M, Ishikawa Y, Sato H, Yoshimori T, Saito S, and Sugamura K

Virology 349(2):254-63, 2006 Jun 5 - Who cited this? | PubMed ID: 16643977 | Fulltext

OX40-OX40 ligand interaction through T cell-T cell contact contributes to CD4 T cell longevity.

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Soroosh P, Ine S, Sugamura K, and Ishii N

Journal of immunology (Baltimore, Md. : 1950) 176(10):5975-87, 2006 May 15 - Who cited this? | PubMed ID: 16670306 | Fulltext

Phage phiC31 integrase-mediated genomic integration of the common cytokine receptor gamma chain in human T-cell lines.

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Ishikawa Y, Tanaka N, Murakami K, Uchiyama T, Kumaki S, Tsuchiya S, Kugoh H, Oshimura M, Calos MP, and Sugamura K

The journal of gene medicine 8(5):646-53, 2006 May - Who cited this? | PubMed ID: 16508910 | Fulltext

Acute myocardial infarction induced by cisplatin-based combination chemotherapy for malignant melanoma: a case report.

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Fukunaga T, Soejima H, Sugamura K, Kojima S, Sugiyama S, Sakamoto T, Yoshimura M, Tanoue T, Kageshita T, Ono T, and Ogawa H

Journal of cardiology 47(4):191-5, 2006 Apr - Who cited this? | PubMed ID: 16637253 | Fulltext

Important role of endogenous erythropoietin system in recruitment of endothelial progenitor cells in hypoxia-induced pulmonary hypertension in mice.

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Satoh K, Kagaya Y, Nakano M, Ito Y, Ohta J, Tada H, Karibe A, Minegishi N, Suzuki N, Yamamoto M, Ono M, Watanabe J, Shirato K, Ishii N, Sugamura K, and Shimokawa H

Circulation 113(11):1442, 2006 Mar 21 - Who cited this? | PubMed ID: 16534010 | Fulltext

Application of HSVtk suicide gene to X-SCID gene therapy: ganciclovir treatment offsets gene corrected X-SCID B cells.

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Uchiyama T, Kumaki S, Ishikawa Y, Onodera M, Sato M, Du W, Sasahara Y, Tanaka N, Sugamura K, and Tsuchiya S

Biochemical and biophysical research communications 341(2):391, 2006 Mar 10 - Who cited this? | PubMed ID: 16426573 | Fulltext

Regulatory T cell-like activity of Foxp3+ adult T cell leukemia cells.

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Chen S, Ishii N, Ine S, Ikeda S, Fujimura T, Ndhlovu LC, Soroosh P, Tada K, Harigae H, Kameoka J, Kasai N, Sasaki T, and Sugamura K

International immunology 18(2):269, 2006 Feb - Who cited this? | PubMed ID: 16361311 | Fulltext

Aberrant activation of the interleukin-2 autocrine loop through the nuclear factor of activated T cells by nonleukemogenic human T-cell leukemia virus type 2 but not by leukemogenic type 1 virus.

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Niinuma A, Higuchi M, Takahashi M, Oie M, Tanaka Y, Gejyo F, Tanaka N, Sugamura K, Xie L, Green PL, and Fujii M

Journal of virology 79(18):11925-34, 2005 Sep - Who cited this? | PubMed ID: 16140768 | Fulltext

During viral infection of the respiratory tract, CD27, 4-1BB, and OX40 collectively determine formation of CD8+ memory T cells and their capacity for secondary expansion.

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Hendriks J, Xiao Y, Rossen JW, van der Sluijs KF, Sugamura K, Ishii N, and Borst J

Journal of immunology (Baltimore, Md. : 1950) 175(3):1665-76, 2005 Aug 1 - Who cited this? | PubMed ID: 16034107 | Fulltext

Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility.

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Wang X, Ria M, Kelmenson PM, Eriksson P, Higgins DC, Samnegård A, Petros C, Rollins J, Bennet AM, Wiman B, de Faire U, Wennberg C, Olsson PG, Ishii N, Sugamura K, Hamsten A,

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Nature genetics 37(4):365-72, 2005 Apr - Who cited this? | PubMed ID: 15750594 | Fulltext

Hrs, a mammalian master molecule in vesicular transport and protein sorting, suppresses the degradation of ESCRT proteins signal transducing adaptor molecule 1 and 2.

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Kobayashi H, Tanaka N, Asao H, Miura S, Kyuuma M, Semura K, Ishii N, and Sugamura K

The Journal of biological chemistry 280(11):10468-77, 2005 Mar 18 - Who cited this? | PubMed ID: 15640163 | Fulltext

Human Parvovirus B19 nonstructural protein transactivates the p21/WAF1 through Sp1.

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Nakashima A, Morita E, Saito S, and Sugamura K

Virology 329(2):493-504, 2004 Nov 24 - Who cited this? | PubMed ID: 15518826 | Fulltext

Ibudilast, a nonselective phosphodiesterase inhibitor, regulates Th1/Th2 balance and NKT cell subset in multiple sclerosis.

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Feng J, Misu T, Fujihara K, Sakoda S, Nakatsuji Y, Fukaura H, Kikuchi S, Tashiro K, Suzumura A, Ishii N, Sugamura K, Nakashima I, and Itoyama Y

Multiple sclerosis (Houndmills, Basingstoke, England) 10(5):494-8, 2004 Oct - Who cited this? | PubMed ID: 15471363 | Fulltext

Therapeutic targeting of the effector T-cell co-stimulatory molecule OX40.

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Sugamura K, Ishii N, and Weinberg AD

Nature reviews. Immunology 4(6):420-31, 2004 Jun - Who cited this? | PubMed ID: 15173831 | Fulltext

Essential role of OX40L on B cells in persistent alloantibody production following repeated alloimmunizations.

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Kato H, Kojima H, Ishii N, Hase H, Imai Y, Fujibayashi T, Sugamura K, and Kobata T

Journal of clinical immunology 24(3):237-48, 2004 May - Who cited this? | PubMed ID: 15114054 | Fulltext

Adenovirus vector-mediated in vivo gene transfer of OX40 ligand to tumor cells enhances antitumor immunity of tumor-bearing hosts.

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Andarini S, Kikuchi T, Nukiwa M, Pradono P, Suzuki T, Ohkouchi S, Inoue A, Maemondo M, Ishii N, Saijo Y, Sugamura K, and Nukiwa T

Cancer research 64(9):3281-7, 2004 May 1 - Who cited this? | PubMed ID: 15126371 | Fulltext

Distinct roles for the OX40-OX40 ligand interaction in regulatory and nonregulatory T cells.

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Takeda I, Ine S, Killeen N, Ndhlovu LC, Murata K, Satomi S, Sugamura K, and Ishii N

Journal of immunology (Baltimore, Md. : 1950) 172(6):3580-9, 2004 Mar 15 - Who cited this? | PubMed ID: 15004159 | Fulltext

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