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Papers authored by Stoffel RH

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Eleven Amino Acid Glucagon-like Peptide-1 Receptor Agonists with Antidiabetic Activity.

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Mapelli C, Natarajan SI, Meyer JP, Bastos MM, Bernatowicz MS, Lee VG, Pluscec J, Riexinger DJ, Sieber-McMaster ES, Constantine KL, Smith-Monroy CA, Golla R, Ma Z, Longhi DA, Shi D, Xin L,

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Journal of medicinal chemistry 52(23):7788-99, 2009 Dec 10 - Who cited this? | PubMed ID: 19702274 | Fulltext

Scalable synthesis and isolation of the four stereoisomers of methyl 1-amino-3-(4-bromophenyl)cyclopentanecarboxylate, useful intermediates for the synthesis of S1P1 receptor agonists.

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Wallace GA, Gordon TD, Hayes ME, Konopacki DB, Fix-Stenzel SR, Zhang X, Grongsaard P, Cusack KP, Schaffter LM, Henry RF, and Stoffel RH

The Journal of organic chemistry 74(13):4886-9, 2009 Jul 3 - Who cited this? | PubMed ID: 19489574 | Fulltext

Lead identification of 2-iminobenzimidazole antagonists of the chemokine receptor CXCR3.

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Hayes ME, Breinlinger EC, Wallace GA, Grongsaard P, Miao W, McPherson MJ, Stoffel RH, Green DW, and Roth GP

Bioorganic & medicinal chemistry letters 18(7):2414-9, 2008 Apr 1 - Who cited this? | PubMed ID: 18337097 | Fulltext

Discovery of small molecule benzimidazole antagonists of the chemokine receptor CXCR3.

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Hayes ME, Wallace GA, Grongsaard P, Bischoff A, George DM, Miao W, McPherson MJ, Stoffel RH, Green DW, and Roth GP

Bioorganic & medicinal chemistry letters 18(5):1573-6, 2008 Mar 1 - Who cited this? | PubMed ID: 18242988 | Fulltext

Discovery of a potent and novel motilin agonist.

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Li JJ, Chao HG, Wang H, Tino JA, Lawrence RM, Ewing WR, Ma Z, Yan M, Slusarchyk D, Seethala R, Sun H, Li D, Burford NT, Stoffel RH, Salyan ME, Li CY,

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Journal of medicinal chemistry 47(7):1704-8, 2004 Mar 25 - Who cited this? | PubMed ID: 15027861 | Fulltext

Palmitoylation increases the kinase activity of the G protein-coupled receptor kinase, GRK6.

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Stoffel RH, Inglese J, Macrae AD, Lefkowitz RJ, and Premont RT

Biochemistry 37(46):16053-9, 1998 Nov 17 - Who cited this? | PubMed ID: 9819198 | Fulltext

The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange.

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Hall RA, Premont RT, Chow CW, Blitzer JT, Pitcher JA, Claing A, Stoffel RH, Barak LS, Shenolikar S, Weinman EJ, Grinstein S, and Lefkowitz RJ

Nature 392(6676):626-30, 1998 Apr 9 - Who cited this? | PubMed ID: 9560162 | Fulltext

Phosphorylation and desensitization of human endothelin A and B receptors. Evidence for G protein-coupled receptor kinase specificity.

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Freedman NJ, Ament AS, Oppermann M, Stoffel RH, Exum ST, and Lefkowitz RJ

The Journal of biological chemistry 272(28):17734-43, 1997 Jul 11 - Who cited this? | PubMed ID: 9211925 | Fulltext

Targeting G protein-coupled receptor kinases to their receptor substrates.

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Stoffel RH, Pitcher JA, and Lefkowitz RJ

The Journal of membrane biology 157(1):1-8, 1997 May 1 - Who cited this? | PubMed ID: 9141353 | Fulltext

Receptor and G betagamma isoform-specific interactions with G protein-coupled receptor kinases.

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Daaka Y, Pitcher JA, Richardson M, Stoffel RH, Robishaw JD, and Lefkowitz RJ

Proceedings of the National Academy of Sciences of the United States of America 94(6):2180-5, 1997 Mar 18 - Who cited this? | PubMed ID: 9122168 | Fulltext

Phosphatidylinositol 4,5-bisphosphate (PIP2)-enhanced G protein-coupled receptor kinase (GRK) activity. Location, structure, and regulation of the PIP2 binding site distinguishes the GRK subfamilies.

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Pitcher JA, Fredericks ZL, Stone WC, Premont RT, Stoffel RH, Koch WJ, and Lefkowitz RJ

The Journal of biological chemistry 271(40):24907-13, 1996 Oct 4 - Who cited this? | PubMed ID: 8798768 | Fulltext

Characterization of the G protein-coupled receptor kinase GRK4. Identification of four splice variants.

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Premont RT, Macrae AD, Stoffel RH, Chung N, Pitcher JA, Ambrose C, Inglese J, MacDonald ME, and Lefkowitz RJ

The Journal of biological chemistry 271(11):6403-10, 1996 Mar 15 - Who cited this? | PubMed ID: 8626439 | Fulltext

G protein-coupled receptor kinase mediates desensitization of norepinephrine-induced Ca2+ channel inhibition.

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Diverse-Pierluissi M, Inglese J, Stoffel RH, Lefkowitz RJ, and Dunlap K

Neuron 16(3):579-85, 1996 Mar - Who cited this? | PubMed ID: 8785055 | Fulltext

A region of adenylyl cyclase 2 critical for regulation by G protein beta gamma subunits.

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Chen J, DeVivo M, Dingus J, Harry A, Li J, Sui J, Carty DJ, Blank JL, Exton JH, and Stoffel RH

Science (New York, N.Y.) 268(5214):1166-9, 1995 May 26 - Who cited this? | PubMed ID: 7761832 | Fulltext

Palmitoylation of G protein-coupled receptor kinase, GRK6. Lipid modification diversity in the GRK family.

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Stoffel RH, Randall RR, Premont RT, Lefkowitz RJ, and Inglese J

The Journal of biological chemistry 269(45):27791-4, 1994 Nov 11 - Who cited this? | PubMed ID: 7961702 | Fulltext

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