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Papers authored by Spector TD

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The genetic epidemiology of osteoarthritis.

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Valdes AM and Spector TD

Current opinion in rheumatology 22(2):139-43, 2010 Mar - Who cited this? | PubMed ID: 20090528 | Fulltext

Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies.

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Kung AW, Xiao SM, Cherny S, Li GH, Gao Y, Tso G, Lau KS, Luk KD, Liu JM, Cui B, Zhang MJ, Zhang ZL, He JW, Yue H, Xia WB, Luo LM,

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American journal of human genetics 86(2):229-39, 2010 Feb 12 - Who cited this? | PubMed ID: 20096396 | Fulltext

Vertebral anti-fracture efficacy of strontium ranelate according to pre-treatment bone turnover.

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Collette J, Bruyère O, Kaufman JM, Lorenc R, Felsenberg D, Spector TD, Diaz-Curiel M, Boonen S, and Reginster JY

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 21(2):233-41, 2010 Feb - Who cited this? | PubMed ID: 19436941 | Fulltext

A genome-wide perspective of genetic variation in human metabolism.

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Illig T, Gieger C, Zhai G, Römisch-Margl W, Wang-Sattler R, Prehn C, Altmaier E, Kastenmüller G, Kato BS, Mewes HW, Meitinger T, de Angelis MH, Kronenberg F, Soranzo N, Wichmann HE, Spector TD,

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Nature genetics 42(2):137-41, 2010 Feb - Who cited this? | PubMed ID: 20037589 | Fulltext

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.

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Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, Elliott P,

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Nature genetics 42(2):105-16, 2010 Feb - Who cited this? | PubMed ID: 20081858 | Fulltext

A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22.

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Kerkhof HJ, Lories RJ, Meulenbelt I, Jonsdottir I, Valdes AM, Arp P, Ingvarsson T, Jhamai M, Jonsson H, Stolk L, Thorleifsson G, Zhai G, Zhang F, Zhu Y, van der Breggen R, Carr A,

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Arthritis and rheumatism 62(2):499-510, 2010 Feb - Who cited this? | PubMed ID: 20112360 | Fulltext

The clinical relevance of genetic susceptibility to osteoarthritis.

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Valdes AM and Spector TD

Best practice & research. Clinical rheumatology 24(1):3-14, 2010 Feb - Who cited this? | PubMed ID: 20129195 | Fulltext

Phenotypic and Genetic Relations Between the HEXACO Dimensions and Trait Emotional Intelligence.

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Veselka L, Petrides KV, Schermer JA, Cherkas LF, Spector TD, and Vernon PA

Twin research and human genetics : the official journal of the International Society for Twin Studies 13(1):66-71, 2010 Feb - Who cited this? | PubMed ID: 20158308 | Fulltext

Genome-wide association study identifies five loci associated with lung function.

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Repapi E, Sayers I, Wain LV, Burton PR, Johnson T, Obeidat M, Zhao JH, Ramasamy A, Zhai G, Vitart V, Huffman JE, Igl W, Albrecht E, Deloukas P, Henderson J, Granell R,

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Nature genetics 42(1):36-44, 2010 Jan - Who cited this? | PubMed ID: 20010834 | Fulltext

Quantitative trait loci for CD4:CD8 lymphocyte ratio are associated with risk of type 1 diabetes and HIV-1 immune control.

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Ferreira MA, Mangino M, Brumme CJ, Zhao ZZ, Medland SE, Wright MJ, Nyholt DR, Gordon S, Campbell M, McEvoy BP, Henders A, Evans DM, Lanchbury JS, Pereyra F, International HIV Controllers Study, Walker BD,

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American journal of human genetics 86(1):88-92, 2010 Jan - Who cited this? | PubMed ID: 20045101 | Fulltext

A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.

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Need AC, Attix DK, McEvoy JM, Cirulli ET, Linney KL, Hunt P, Ge D, Heinzen EL, Maia JM, Shianna KV, Weale ME, Cherkas LF, Clement G, Spector TD, Gibson G, and Goldstein DB

Human molecular genetics 18(23):4650-61, 2009 Dec 1 - Who cited this? | PubMed ID: 19734545 | Fulltext

Association of the DVWA and GDF5 polymorphisms with osteoarthritis in UK populations.

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Valdes AM, Spector TD, Doherty S, Wheeler M, Hart DJ, and Doherty M

Annals of the rheumatic diseases 68(12):1916-20, 2009 Dec - Who cited this? | PubMed ID: 19054821 | Fulltext

Common Sequence Variation in FLNB Regulates Bone Structure in Women in the General Population and FLNB mRNA Expression in Osteoblasts In Vitro.

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Wilson SG, Jones MR, Mullin BH, Dick IM, Richards JB, Pastinen TM, Grundberg E, Ljunggren O, Surdulescu GL, Dudbridge F, Elliott KS, Cervino AC, Spector TD, and Prince RL

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 24(12):1989-97, 2009 Dec - Who cited this? | PubMed ID: 19453265 | Fulltext

A Genome-Wide Association Study Reveals Variants in ARL15 that Influence Adiponectin Levels.

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Richards JB, Waterworth D, O'Rahilly S, Hivert MF, Loos RJ, Perry JR, Tanaka T, Timpson NJ, Semple RK, Soranzo N, Song K, Rocha N, Grundberg E, Dupuis J, Florez JC, Langenberg C,

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PLoS genetics 5(12):e1000768, 2009 Dec - Who cited this? | PubMed ID: 20011104 | Fulltext

Heritability of insulin sensitivity and lipid profile depend on BMI: evidence for gene-obesity interaction.

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Wang X, Ding X, Su S, Spector TD, Mangino M, Iliadou A, and Snieder H

Diabetologia 52(12):2578-84, 2009 Dec - Who cited this? | PubMed ID: 19820914 | Fulltext

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.

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Soranzo N, Spector TD, Mangino M, Kühnel B, Rendon A, Teumer A, Willenborg C, Wright B, Chen L, Li M, Salo P, Voight BF, Burns P, Laskowski RA, Xue Y, Menzel S,

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Nature genetics 41(11):1182-90, 2009 Nov - Who cited this? | PubMed ID: 19820697 | Fulltext

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.

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Ganesh SK, Zakai NA, van Rooij FJ, Soranzo N, Smith AV, Nalls MA, Chen MH, Kottgen A, Glazer NL, Dehghan A, Kuhnel B, Aspelund T, Yang Q, Tanaka T, Jaffe A, Bis JC,

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Nature genetics 41(11):1191-8, 2009 Nov - Who cited this? | PubMed ID: 19862010 | Fulltext

Repeated measures of intraocular pressure result in higher heritability and greater power in genetic linkage studies.

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Carbonaro F, Andrew T, Mackey DA, Young TL, Spector TD, and Hammond CJ

Investigative ophthalmology & visual science 50(11):5115-9, 2009 Nov - Who cited this? | PubMed ID: 19420339 | Fulltext

No clear genetic influences on the association between dyslexia and anxiety in a population-based sample of female twins.

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Whitehouse AJ, Spector TD, and Cherkas LF

Dyslexia (Chichester, England) 15(4):282-90, 2009 Nov - Who cited this? | PubMed ID: 19025968 | Fulltext

Multicenter dizygotic twin cohort study confirms two linkage susceptibility loci for body mass index at 3q29 and 7q36 and identifies three further potential novel loci.

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Kettunen J, Perola M, Martin NG, Cornes BK, Wilson SG, Montgomery GW, Benyamin B, Harris JR, Boomsma D, Willemsen G, Hottenga JJ, Slagboom PE, Christensen K, Kyvik KO, Sørensen TI, Pedersen NL,

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International journal of obesity (2005) 33(11):1235-42, 2009 Nov - Who cited this? | PubMed ID: 19721450 | Fulltext

Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture.

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Richards JB, Kavvoura FK, Rivadeneira F, Styrkársdóttir U, Estrada K, Halldórsson BV, Hsu YH, Zillikens MC, Wilson SG, Mullin BH, Amin N, Aulchenko YS, Cupples LA, Deloukas P, Demissie S, Hofman A,

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Annals of internal medicine 151(8):528-37, 2009 Oct 20 - Who cited this? | PubMed ID: 19841454 | Fulltext

A General Factor of Personality: Evidence from the HEXACO Model and a Measure of Trait Emotional Intelligence.

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Veselka L, Schermer JA, Petrides KV, Cherkas LF, Spector TD, and Vernon PA

Twin research and human genetics : the official journal of the International Society for Twin Studies 12(5):420-4, 2009 Oct - Who cited this? | PubMed ID: 19803769 | Fulltext

A genome-wide association study suggests that a locus within the ataxin 2 binding protein 1 gene is associated with hand osteoarthritis: the Treat-OA consortium.

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Zhai G, van Meurs JB, Livshits G, Meulenbelt I, Valdes AM, Soranzo N, Hart D, Zhang F, Kato BS, Richards JB, Williams FM, Inouye M, Kloppenburg M, Deloukas P, Slagboom E, Uitterlinden A,

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Journal of medical genetics 46(9):614-6, 2009 Sep - Who cited this? | PubMed ID: 19508968 | Fulltext

Further genetic evidence suggesting a role for the RhoGTPase-RhoGEF pathway in osteoporosis.

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Mullin BH, Prince RL, Mamotte C, Spector TD, Hart DJ, Dudbridge F, and Wilson SG

Bone 45(2):387-91, 2009 Aug - Who cited this? | PubMed ID: 19427924 | Fulltext

An obesogenic postnatal environment is more important than the fetal environment for the development of adult adiposity: a study of female twins.

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Skidmore PM, Cassidy A, Swaminathan R, Richards JB, Mangino M, Spector TD, and MacGregor AJ

The American journal of clinical nutrition 90(2):401-6, 2009 Aug - Who cited this? | PubMed ID: 19553297 | Fulltext

Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi.

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Falchi M, Bataille V, Hayward NK, Duffy DL, Bishop JA, Pastinen T, Cervino A, Zhao ZZ, Deloukas P, Soranzo N, Elder DE, Barrett JH, Martin NG, Bishop DT, Montgomery GW, and Spector TD

Nature genetics 41(8):915-9, 2009 Aug - Who cited this? | PubMed ID: 19578365 | Fulltext

A genome-wide association study identifies a novel locus on chromosome 18q12.2 influencing white cell telomere length.

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Mangino M, Richards JB, Soranzo N, Zhai G, Aviv A, Valdes AM, Samani NJ, Deloukas P, and Spector TD

Journal of medical genetics 46(7):451-4, 2009 Jul - Who cited this? | PubMed ID: 19359265 | Fulltext

Emotional intelligence and its association with orgasmic frequency in women.

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Burri AV, Cherkas LM, and Spector TD

The journal of sexual medicine 6(7):1930-7, 2009 Jul - Who cited this? | PubMed ID: 19453897 | Fulltext

Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford study.

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Livshits G, Zhai G, Hart DJ, Kato BS, Wang H, Williams FM, and Spector TD

Arthritis and rheumatism 60(7):2037-45, 2009 Jul - Who cited this? | PubMed ID: 19565477 | Fulltext

Variation at the ANP32A gene is associated with risk of hip osteoarthritis in women.

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Valdes AM, Lories RJ, van Meurs JB, Kerkhof H, Doherty S, Hofman A, Hart DJ, Zhang F, Luyten FP, Uitterlinden AG, Doherty M, and Spector TD

Arthritis and rheumatism 60(7):2046-54, 2009 Jul - Who cited this? | PubMed ID: 19565487 | Fulltext

EPHA2 Is Associated with Age-Related Cortical Cataract in Mice and Humans.

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Jun G, Guo H, Klein BE, Klein R, Wang JJ, Mitchell P, Miao H, Lee KE, Joshi T, Buck M, Chugha P, Bardenstein D, Klein AP, Bailey-Wilson JE, Gong X, Spector TD,

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PLoS genetics 5(7):e1000584, 2009 Jul - Who cited this? | PubMed ID: 19649315 | Fulltext

Bivariate genetic modelling of the response to an oral glucose tolerance challenge: a gene x environment interaction approach.

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Liu GF, Riese H, Spector TD, Mangino M, O'Dell SD, Stolk RP, and Snieder H

Diabetologia 52(6):1048-55, 2009 Jun - Who cited this? | PubMed ID: 19288074 | Fulltext

Genetic and environmental determinants on bone loss in postmenopausal Caucasian women: a 14-year longitudinal twin study.

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Zhai G, Andrew T, Kato BS, Blake GM, and Spector TD

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20(6):949-53, 2009 Jun - Who cited this? | PubMed ID: 18810303 | Fulltext

Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations.

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Kolz M, Johnson T, Sanna S, Teumer A, Vitart V, Perola M, Mangino M, Albrecht E, Wallace C, Farrall M, Johansson A, Nyholt DR, Aulchenko Y, Beckmann JS, Bergmann S, Bochud M,

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PLoS genetics 5(6):e1000504, 2009 Jun - Who cited this? | PubMed ID: 19503597 | Fulltext

Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand.

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Evangelou E, Chapman K, Meulenbelt I, Karassa FB, Loughlin J, Carr A, Doherty M, Doherty S, Gómez-Reino JJ, Gonzalez A, Halldorsson BV, Hauksson VB, Hofman A, Hart DJ, Ikegawa S, Ingvarsson T,

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Arthritis and rheumatism 60(6):1710-21, 2009 Jun - Who cited this? | PubMed ID: 19479880 | Fulltext

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.

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Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L, Speliotes EK, Thorleifsson G, Willer CJ, Herrera BM, Jackson AU, Lim N, Scheet P, Soranzo N, Amin N, Aulchenko YS,

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PLoS genetics 5(6):e1000508, 2009 Jun - Who cited this? | PubMed ID: 19557161 | Fulltext

Geographical structure and differential natural selection among North European populations.

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McEvoy BP, Montgomery GW, McRae AF, Ripatti S, Perola M, Spector TD, Cherkas L, Ahmadi KR, Boomsma D, Willemsen G, Hottenga JJ, Pedersen NL, Magnusson PK, Kyvik KO, Christensen K, Kaprio J,

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Genome research 19(5):804-14, 2009 May - Who cited this? | PubMed ID: 19265028 | Fulltext

A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function.

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Soranzo N, Rendon A, Gieger C, Jones CI, Watkins NA, Menzel S, Döring A, Stephens J, Prokisch H, Erber W, Potter SC, Bray SL, Burns P, Jolley J, Falchi M, Kühnel B,

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Blood 113(16):3831-7, 2009 Apr 16 - Who cited this? | PubMed ID: 19221038 | Fulltext

Common variants in the region around Osterix are associated with bone mineral density and growth in childhood.

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Timpson NJ, Tobias JH, Richards JB, Soranzo N, Duncan EL, Sims AM, Whittaker P, Kumanduri V, Zhai G, Glaser B, Eisman J, Jones G, Nicholson G, Prince R, Seeman E, Spector TD,

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Human molecular genetics 18(8):1510-7, 2009 Apr 15 - Who cited this? | PubMed ID: 19181680 | Fulltext

Identification of quantitative trait loci for fibrin clot phenotypes: the EuroCLOT study.

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Williams FM, Carter AM, Kato B, Falchi M, Bathum L, Surdulescu G, Kyvik KO, Palotie A, Spector TD, Grant PJ, and EuroCLOT Investigators

Arteriosclerosis, thrombosis, and vascular biology 29(4):600-5, 2009 Apr - Who cited this? | PubMed ID: 19150881 | Fulltext

Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size.

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Soranzo N, Rivadeneira F, Chinappen-Horsley U, Malkina I, Richards JB, Hammond N, Stolk L, Nica A, Inouye M, Hofman A, Stephens J, Wheeler E, Arp P, Gwilliam R, Jhamai PM, Potter S,

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PLoS genetics 5(4):e1000445, 2009 Apr - Who cited this? | PubMed ID: 19343178 | Fulltext

The genetic influence on radiographic osteoarthritis is site specific at the hand, hip and knee.

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Macgregor AJ, Li Q, Spector TD, and Williams FM

Rheumatology (Oxford, England) 48(3):277-80, 2009 Mar - Who cited this? | PubMed ID: 19153142 | Fulltext

A new 5-lipoxygenase inhibitor seems to be safe and effective for the treatment of osteoarthritis.

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Williams FM and Spector TD

Nature clinical practice. Rheumatology 5(3):132-3, 2009 Mar - Who cited this? | PubMed ID: 19190622 | Fulltext

Ethnic differences in F cell levels in Jamaica: a potential tool for identifying new genetic loci controlling fetal haemoglobin.

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Creary LE, McKenzie CA, Menzel S, Hanchard NA, Taylor V, Hambleton I, Spector TD, Forrester TE, and Thein SL

British journal of haematology 144(6):954-60, 2009 Mar - Who cited this? | PubMed ID: 19120354 | Fulltext

Genome-wide association study of smoking initiation and current smoking.

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Vink JM, Smit AB, de Geus EJ, Sullivan P, Willemsen G, Hottenga JJ, Smit JH, Hoogendijk WJ, Zitman FG, Peltonen L, Kaprio J, Pedersen NL, Magnusson PK, Spector TD, Kyvik KO, Morley KI,

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American journal of human genetics 84(3):367-79, 2009 Mar - Who cited this? | PubMed ID: 19268276 | Fulltext

The genetics and epidemiology of female sexual dysfunction: a review.

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Burri AV, Cherkas LM, and Spector TD

The journal of sexual medicine 6(3):646-57, 2009 Mar - Who cited this? | PubMed ID: 19143906 | Fulltext

Plasma adiponectin concentrations are associated with body composition and plant-based dietary factors in female twins.

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Cassidy A, Skidmore P, Rimm EB, Welch A, Fairweather-Tait S, Skinner J, Burling K, Richards JB, Spector TD, and MacGregor AJ

The Journal of nutrition 139(2):353-8, 2009 Feb - Who cited this? | PubMed ID: 19106327 | Fulltext

The contribution of genes to osteoarthritis.

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Valdes AM and Spector TD

The Medical clinics of North America 93(1):45-66, 2009 Jan - Who cited this? | PubMed ID: 19059021 | Fulltext

Effective measurement of knee alignment using AP knee radiographs.

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Colebatch AN, Hart DJ, Zhai G, Williams FM, Spector TD, and Arden NK

The Knee 16(1):42-5, 2009 Jan - Who cited this? | PubMed ID: 18790641 | Fulltext

Variants in MTNR1B influence fasting glucose levels.

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Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, Kaakinen M,

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Nature genetics 41(1):77-81, 2009 Jan - Who cited this? | PubMed ID: 19060907 | Fulltext

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Papers authored by Spector TD

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