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Papers authored by Sparwasser T

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Nonfunctional regulatory T cells and defective control of th2 cytokine production in natural scurfy mutant mice.

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Lahl K, Mayer CT, Bopp T, Huehn J, Loddenkemper C, Eberl G, Wirnsberger G, Dornmair K, Geffers R, Schmitt E, Buer J, and Sparwasser T

Journal of immunology (Baltimore, Md. : 1950) 183(9):5662-72, 2009 Nov 1 - Who cited this? | PubMed ID: 19812199 | Fulltext

The regulatory T-cell response during acute retroviral infection is locally defined and controls the magnitude and duration of the virus-specific cytotoxic T-cell response.

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Zelinskyy G, Dietze KK, Hüsecken YP, Schimmer S, Nair S, Werner T, Gibbert K, Kershaw O, Gruber AD, Sparwasser T, and Dittmer U

Blood 114(15):3199-207, 2009 Oct 8 - Who cited this? | PubMed ID: 19671923 | Fulltext

Conventional bone marrow-derived dendritic cells contribute to toll-like receptor-independent production of alpha/beta interferon in response to inactivated parapoxvirus ovis.

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Siegemund S, Hartl A, von Buttlar H, Dautel F, Raue R, Freudenberg MA, Fejer G, Büttner M, Köhler G, Kirschning CJ, Sparwasser T, and Alber G

Journal of virology 83(18):9411-22, 2009 Sep - Who cited this? | PubMed ID: 19570869 | Fulltext

Regulatory T cells suppress antiviral immune responses and increase viral loads during acute infection with a lymphotropic retrovirus.

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Zelinskyy G, Dietze K, Sparwasser T, and Dittmer U

PLoS pathogens 5(8):e1000406, 2009 Aug - Who cited this? | PubMed ID: 19714239 | Fulltext

Secretory phospholipase A2-IID is an effector molecule of CD4+CD25+ regulatory T cells.

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von Allmen CE, Schmitz N, Bauer M, Hinton HJ, Kurrer MO, Buser RB, Gwerder M, Muntwiler S, Sparwasser T, Beerli RR, and Bachmann MF

Proceedings of the National Academy of Sciences of the United States of America 106(28):11673-8, 2009 Jul 14 - Who cited this? | PubMed ID: 19564598 | Fulltext

Corrigendum: Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies.

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Pellegrini M, Calzascia T, Elford AR, Shahinian A, Lin AE, Dissanayake D, Dhanji S, Nguyen LT, Gronski MA, Morre M, Assouline B, Lahl K, Sparwasser T, Ohashi PS, and Mak TW

Nature medicine 15(7):819, 2009 Jul - Who cited this? | PubMed ID: 19584868 | Fulltext

Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies.

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Pellegrini M, Calzascia T, Elford AR, Shahinian A, Lin AE, Dissanayake D, Dhanji S, Nguyen LT, Gronski MA, Morre M, Assouline B, Lahl K, Sparwasser T, Ohashi PS, and Mak TW

Nature medicine 15(5):528-36, 2009 May - Who cited this? | PubMed ID: 19396174 | Fulltext

DC activated via dectin-1 convert Treg into IL-17 producers.

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Osorio F, Leibundgut-Landmann S, Lochner M, Lahl K, Sparwasser T, Eberl G, and Reis E Sousa C

European journal of immunology 38(12):3274-81, 2008 Dec - Who cited this? | PubMed ID: 19039774 | Fulltext

Circumvention of regulatory CD4(+) T cell activity during cross-priming strongly enhances T cell-mediated immunity.

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Heit A, Gebhardt F, Lahl K, Neuenhahn M, Schmitz F, Anderl F, Wagner H, Sparwasser T, Busch DH, and Kastenmüller K

European journal of immunology 38(6):1585-97, 2008 Jun - Who cited this? | PubMed ID: 18465771 | Fulltext

Decreased Pathology and Prolonged Survival of Human DC-SIGN Transgenic Mice during Mycobacterial Infection.

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Schaefer M, Reiling N, Fessler C, Stephani J, Taniuchi I, Hatam F, Yildirim AO, Fehrenbach H, Walter K, Ruland J, Wagner H, Ehlers S, and Sparwasser T

Journal of immunology (Baltimore, Md. : 1950) 180(10):6836-45, 2008 May 15 - Who cited this? | PubMed ID: 18453604 | Fulltext

BAC to immunology--bacterial artificial chromosome-mediated transgenesis for targeting of immune cells.

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Sparwasser T and Eberl G

Immunology 121(3):308-13, 2007 Jul - Who cited this? | PubMed ID: 17437533 | Fulltext

Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease.

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Lahl K, Loddenkemper C, Drouin C, Freyer J, Arnason J, Eberl G, Hamann A, Wagner H, Huehn J, and Sparwasser T

The Journal of experimental medicine 204(1):57-63, 2007 Jan 22 - Who cited this? | PubMed ID: 17200412 | Fulltext

Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity.

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Gross O, Gewies A, Finger K, Schäfer M, Sparwasser T, Peschel C, Förster I, and Ruland J

Nature 442(7103):651-6, 2006 Aug 10 - Who cited this? | PubMed ID: 16862125 | Fulltext

The Bcl10-Malt1 complex segregates Fc epsilon RI-mediated nuclear factor kappa B activation and cytokine production from mast cell degranulation.

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Klemm S, Gutermuth J, Hültner L, Sparwasser T, Behrendt H, Peschel C, Mak TW, Jakob T, and Ruland J

The Journal of experimental medicine 203(2):337-47, 2006 Feb 20 - Who cited this? | PubMed ID: 16432253 | Fulltext

Toll-like receptor 9 contributes to recognition of Mycobacterium bovis Bacillus Calmette-Guérin by Flt3-ligand generated dendritic cells.

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von Meyenn F, Schaefer M, Weighardt H, Bauer S, Kirschning CJ, Wagner H, and Sparwasser T

Immunobiology 211(6-8):557-65, 2006 - Who cited this? | PubMed ID: 16920494 | Fulltext

General method for the modification of different BAC types and the rapid generation of BAC transgenic mice.

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Sparwasser T, Gong S, Li JY, and Eberl G

Genesis (New York, N.Y. : 2000) 38(1):39-50, 2004 Jan - Who cited this? | PubMed ID: 14755803 | Fulltext

In vivo depletion of CD11c(+) dendritic cells abrogates priming of CD8(+) T cells by exogenous cell-associated antigens.

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Jung S, Unutmaz D, Wong P, Sano G, De los Santos K, Sparwasser T, Wu S, Vuthoori S, Ko K, Zavala F, Pamer EG, Littman DR, and Lang RA

Immunity 17(2):211-20, 2002 Aug - Who cited this? | PubMed ID: 12196292 | Fulltext

Functional and antigenic characterization of human, rhesus macaque, pigtailed macaque, and murine DC-SIGN.

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Baribaud F, Pöhlmann S, Sparwasser T, Kimata MT, Choi YK, Haggarty BS, Ahmad N, Macfarlan T, Edwards TG, Leslie GJ, Arnason J, Reinhart TA, Kimata JT, Littman DR, Hoxie JA, and Doms RW

Journal of virology 75(21):10281-9, 2001 Nov - Who cited this? | PubMed ID: 11581396 | Fulltext

Bacterial CpG-DNA activates dendritic cells in vivo: T helper cell-independent cytotoxic T cell responses to soluble proteins.

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Sparwasser T, Vabulas RM, Villmow B, Lipford GB, and Wagner H

European journal of immunology 30(12):3591-7, 2000 Dec - Who cited this? | PubMed ID: 11169401 | Fulltext

CpG-DNA-mediated transient lymphadenopathy is associated with a state of Th1 predisposition to antigen-driven responses.

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Lipford GB, Sparwasser T, Zimmermann S, Heeg K, and Wagner H

Journal of immunology (Baltimore, Md. : 1950) 165(3):1228-35, 2000 Aug 1 - Who cited this? | PubMed ID: 10903720 | Fulltext

Immunostimulatory CpG-oligonucleotides cause proliferation, cytokine production, and an immunogenic phenotype in chronic lymphocytic leukemia B cells.

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Decker T, Schneller F, Sparwasser T, Tretter T, Lipford GB, Wagner H, and Peschel C

Blood 95(3):999-1006, 2000 Feb 1 - Who cited this? | PubMed ID: 10648415 | Fulltext

Consequences of bacterial CpG DNA-driven activation of antigen-presenting cells.

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Sparwasser T and Lipford GB

Current topics in microbiology and immunology 247:59-75, 2000 - Who cited this? | PubMed ID: 10689779 | Fulltext

Hematopoietic remodeling triggered by CpG DNA.

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Lipford GB and Sparwasser T

Current topics in microbiology and immunology 247:119-29, 2000 - Who cited this? | PubMed ID: 10689783 | Fulltext

Immunostimulatory CpG-oligodeoxynucleotides cause extramedullary murine hemopoiesis.

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Sparwasser T, Hültner L, Koch ES, Luz A, Lipford GB, and Wagner H

Journal of immunology (Baltimore, Md. : 1950) 162(4):2368-74, 1999 Feb 15 - Who cited this? | PubMed ID: 9973517 | Fulltext

CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation.

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Häcker H, Mischak H, Miethke T, Liptay S, Schmid R, Sparwasser T, Heeg K, Lipford GB, and Wagner H

The EMBO journal 17(21):6230-40, 1998 Nov 2 - Who cited this? | PubMed ID: 9799232 | Fulltext

Bacterial DNA as an evolutionary conserved ligand signalling danger of infection to immune cells.

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Heeg K, Sparwasser T, Lipford GB, Häcker H, Zimmermann S, and Wagner H

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 17(7):464-9, 1998 Jul - Who cited this? | PubMed ID: 9764548 | Fulltext

Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells.

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Sparwasser T, Koch ES, Vabulas RM, Heeg K, Lipford GB, Ellwart JW, and Wagner H

European journal of immunology 28(6):2045-54, 1998 Jun - Who cited this? | PubMed ID: 9645386 | Fulltext

Immunostimulatory DNA: sequence-dependent production of potentially harmful or useful cytokines.

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Lipford GB, Sparwasser T, Bauer M, Zimmermann S, Koch ES, Heeg K, and Wagner H

European journal of immunology 27(12):3420-6, 1997 Dec - Who cited this? | PubMed ID: 9464831 | Fulltext

Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor-alpha-mediated shock.

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Sparwasser T, Miethke T, Lipford G, Erdmann A, Häcker H, Heeg K, and Wagner H

European journal of immunology 27(7):1671-9, 1997 Jul - Who cited this? | PubMed ID: 9247576 | Fulltext

Bacterial DNA causes septic shock.

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Sparwasser T, Miethke T, Lipford G, Borschert K, Häcker H, Heeg K, and Wagner H

Nature 386(6623):336-7, 1997 Mar 27 - Who cited this? | PubMed ID: 9121548 | Fulltext

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