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Papers authored by Slusarchyk D

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Discovery and optimization of (R)-prolinol-derived agonists of the Growth Hormone Secretagogue receptor (GHSR).

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Zhai W, Flynn N, Longhi DA, Tino JA, Murphy BJ, Slusarchyk D, Gordon DA, Pendri A, Shi S, Stoffel R, Ma B, Sofia MJ, and Gerritz SW

Bioorganic & medicinal chemistry letters 18(18):5083-6, 2008 Sep 15 - Who cited this? | PubMed ID: 18722770 | Fulltext

(d)-2-tert-Butoxycarbonylamino-5,5-difluoro-5-phenyl-pentanoic acid: Synthesis and incorporation into the growth hormone secretagogues.

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Li J, Chen SY, Murphy BJ, Flynn N, Seethala R, Slusarchyk D, Yan M, Sleph P, Zhang H, Humphreys WG, Ewing WR, Robl JA, Gordon D, and Tino JA

Bioorganic & medicinal chemistry letters 18(14):4072-4, 2008 Jul 15 - Who cited this? | PubMed ID: 18554903 | Fulltext

Tetrazole based amides as growth hormone secretagogues.

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Li JJ, Wang H, Li J, Qu F, Swartz SG, Hernández AS, Biller SA, Robl JA, Tino JA, Slusarchyk D, Seethala R, Sleph P, Yan M, Grover G, Flynn N, Murphy BJ,

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Bioorganic & medicinal chemistry letters 18(8):2536-9, 2008 Apr 15 - Who cited this? | PubMed ID: 18378446 | Fulltext

Optimization of 1H-tetrazole-1-alkanenitriles as potent orally bioavailable growth hormone secretagogues.

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Hernández AS, Swartz SG, Slusarchyk D, Yan M, Seethala RK, Sleph P, Grover G, Dickinson K, Giupponi L, Harper TW, Humphreys WG, Longhi DA, Flynn N, Murphy BJ, Gordon DA, Biller SA,

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Bioorganic & medicinal chemistry letters 18(6):2067-72, 2008 Mar 15 - Who cited this? | PubMed ID: 18282707 | Fulltext

Design and synthesis of tetrazole-based growth hormone secretagogue: the SAR studies of the O-benzyl serine side chain.

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Li J, Chen SY, Tao S, Wang H, Li JJ, Swartz S, Musial C, Hernandez AA, Flynn N, Murphy BJ, Beehler B, Dickinson KE, Giupponi L, Grover G, Seethala R, Sleph P,

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Bioorganic & medicinal chemistry letters 18(6):1825-9, 2008 Mar 15 - Who cited this? | PubMed ID: 18295486 | Fulltext

Discovery of a Tetrazole-Based Growth Hormone Secretagogue: 4-(Hydroxybutyl)carbamic Acid 2-{5-[1-(2-Amino-2-methylpropionylamino)-2- benzyloxyethyl]tetrazol-1-yl}ethyl Ester (BMS-317180).

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Li J, Chen SY, Li JJ, Wang H, Hernandez AS, Tao S, Musial CM, Qu F, Swartz S, Chao ST, Flynn N, Murphy BJ, Slusarchyk DA, Seethala R, Yan M, Sleph P,

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Journal of medicinal chemistry 50(24):5890-3, 2007 Nov 29 - Who cited this? | PubMed ID: 17973363 | Fulltext

Discovery, synthesis, and structure-activity studies of tetrazole based growth hormone secretagogues.

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Hernández AS, Cheng PT, Musial CM, Swartz SG, George RJ, Grover G, Slusarchyk D, Seethala RK, Smith M, Dickinson K, Giupponi L, Longhi DA, Flynn N, Murphy BJ, Gordon DA, Biller SA,

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Bioorganic & medicinal chemistry letters 17(21):5928-33, 2007 Nov 1 - Who cited this? | PubMed ID: 17869100 | Fulltext

Arylpropanolamines: selective beta3 agonists arising from strategies to mitigate phase I metabolic transformations.

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Washburn WN, Harper TW, Wu G, Godfrey JD, McCann P, Girotra R, Shao C, Zhang H, Gavai A, Mikkilineni A, Dejneka T, Ahmed S, Caringal Y, Hangeland J, Zhang M, Cheng PT,

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Bioorganic & medicinal chemistry letters 17(15):4290-6, 2007 Aug 1 - Who cited this? | PubMed ID: 17533126 | Fulltext

Tetrahydroisoquinoline 1-carboxamides as growth hormone secretagogues.

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Li JJ, Wang H, Qu F, Musial C, Tino JA, Robl JA, Slusarchyk D, Golla R, Seethala R, Dickinson K, Giupponi L, Grover G, Sleph P, Flynn N, Murphy BJ, Gordon D,

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Bioorganic & medicinal chemistry letters 15(7):1799-802, 2005 Apr 1 - Who cited this? | PubMed ID: 15780609 | Fulltext

BMS-201620: a selective beta 3 agonist.

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Washburn WN, Sun CQ, Bisacchi G, Wu G, Cheng PT, Sher PM, Ryono D, Gavai AV, Poss K, Girotra RN, McCann PJ, Mikkilineni AB, Dejneka TC, Wang TC, Merchant Z, Morella M,

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Bioorganic & medicinal chemistry letters 14(13):3525-9, 2004 Jul 5 - Who cited this? | PubMed ID: 15177466 | Fulltext

Discovery of a potent and novel motilin agonist.

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Li JJ, Chao HG, Wang H, Tino JA, Lawrence RM, Ewing WR, Ma Z, Yan M, Slusarchyk D, Seethala R, Sun H, Li D, Burford NT, Stoffel RH, Salyan ME, Li CY,

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Journal of medicinal chemistry 47(7):1704-8, 2004 Mar 25 - Who cited this? | PubMed ID: 15027861 | Fulltext

Beta 3 agonists. Part 1: evolution from inception to BMS-194449.

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Washburn WN, Sher PM, Poss KM, Girotra RN, McCann PJ, Gavai AV, Mikkilineni AB, Mathur A, Cheng P, Dejneka TC, Sun CQ, Wang TC, Harper TW, Russell AD, Slusarchyk DA, Skwish S,

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Bioorganic & medicinal chemistry letters 11(23):3035-9, 2001 Dec 3 - Who cited this? | PubMed ID: 11714605 | Fulltext

BMS-196085: a potent and selective full agonist of the human beta(3) adrenergic receptor.

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Gavai AV, Sher PM, Mikkilineni AB, Poss KM, McCann PJ, Girotra RN, Fisher LG, Wu G, Bednarz MS, Mathur A, Wang TC, Sun CQ, Slusarchyk DA, Skwish S, Allen GT, Hillyer DE,

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Bioorganic & medicinal chemistry letters 11(23):3041-4, 2001 Dec 3 - Who cited this? | PubMed ID: 11714606 | Fulltext

alpha-Phosphonosulfonic acids: potent and selective inhibitors of squalene synthase.

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Magnin DR, Biller SA, Chen Y, Dickson JK, Fryszman OM, Lawrence RM, Logan JV, Sieber-McMaster ES, Sulsky RB, Traeger SC, Hsieh DC, Lan SJ, Rinehart JK, Harrity TW, Jolibois KG, Kunselman LK,

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Journal of medicinal chemistry 39(3):657-60, 1996 Feb 2 - Who cited this? | PubMed ID: 8576905 | Fulltext

Phosphorus-containing inhibitors of HMG-CoA reductase. 2. Synthesis and biological activities of a series of substituted pyridines containing a hydroxyphosphinyl moiety.

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Robl JA, Duncan LA, Pluscec J, Karanewsky DS, Gordon EM, Ciosek CP, Rich LC, Dehmel VC, Slusarchyk DA, and Harrity TW

Journal of medicinal chemistry 34(9):2804-15, 1991 Sep - Who cited this? | PubMed ID: 1895299 | Fulltext

Xylocandin: a new complex of antifungal peptides. I. Taxonomy, isolation and biological activity.

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Meyers E, Bisacchi GS, Dean L, Liu WC, Minassian B, Slusarchyk DS, Sykes RB, Tanaka SK, and Trejo W

The Journal of antibiotics 40(11):1515-9, 1987 Nov - Who cited this? | PubMed ID: 3693121 | Fulltext

Catacandins, novel anticandidal antibiotics of bacterial origin.

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Meyers E, Cooper R, Dean L, Johnson JH, Slusarchyk DS, Trejo WH, and Singh PD

The Journal of antibiotics 38(12):1642-8, 1985 Dec - Who cited this? | PubMed ID: 4093330 | Fulltext

Phenacein--an angiotensin-converting enzyme inhibitor produced by a streptomycete. I. Taxonomy, fermentation and biological properties.

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Bush K, Henry PR, Souser-Woehleke M, Trejo WH, and Slusarchyk DS

The Journal of antibiotics 37(11):1308-12, 1984 Nov - Who cited this? | PubMed ID: 6096340 | Fulltext

Muraceins--muramyl peptides produced by Nocardia orientalis as angiotensin-converting enzyme inhibitors. I. Taxonomy, fermentation and biological properties.

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Bush K, Henry PR, and Slusarchyk DS

The Journal of antibiotics 37(4):330-5, 1984 Apr - Who cited this? | PubMed ID: 6327590 | Fulltext

Activity of sulfa drugs and dihydrofolate reductase inhibitors against Candida albicans.

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Bush K, Freudenberger JS, Slusarchyk DS, Sykes RB, and Meyers E

Experientia 38(4):436-7, 1982 Apr 15 - Who cited this? | PubMed ID: 7044814 | Fulltext

Ionomycin, a new polyether antibiotic.

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Liu WC, Slusarchyk DS, Astle G, Trejo WH, Brown WE, and Meyers E

The Journal of antibiotics 31(9):815-9, 1978 Sep - Who cited this? | PubMed ID: 711623 | Fulltext

EM49, a new peptide antibiotic. 3. biological characterization in vitro and in vivo.

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Meyers E, Pansy FE, Basch HI, McRipley RJ, Slusarchyk DS, Graham SF, and Trejo WH

The Journal of antibiotics 26(8):457-62, 1973 Aug - Who cited this? | PubMed ID: 4209832 | Fulltext

Biological characterization of diumycin, a phosphorus-containing glycolipid antibiotic.

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Meyers E, Slusarchyk DS, Pansy FE, Basch HI, and Trejo WH

The Journal of antibiotics 25(3):163-70, 1972 Mar - Who cited this? | PubMed ID: 5034812 | Fulltext

Janiemycin, a new peptide antibiotic.

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Meyers E, Weisenborn FL, Pansy FE, Slusarchyk DS, Von Saltza MH, Rathnum ML, and Parker WL

The Journal of antibiotics 23(10):502-7, 1970 Oct - Who cited this? | PubMed ID: 5482761 | Fulltext

The diumycins. New members of an antibiotic family having prolonged in vivo activity.

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Myers E, Slusarchyk DS, Bouchard JL, and Weisenborn FL

The Journal of antibiotics 22(10):490-3, 1969 Oct - Who cited this? | PubMed ID: 5350506 | Fulltext

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