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Papers authored by Skarnes WC

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Floxin, a resource for genetically engineering mouse ESCs.

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Singla V, Hunkapiller J, Santos N, Seol AD, Norman AR, Wakenight P, Skarnes WC, and Reiter JF

Nature methods 7(1):50-2, 2010 Jan - Who cited this? | PubMed ID: 19966808 | Fulltext

Agouti C57BL/6N embryonic stem cells for mouse genetic resources.

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Pettitt SJ, Liang Q, Rairdan XY, Moran JL, Prosser HM, Beier DR, Lloyd KC, Bradley A, and Skarnes WC

Nature methods 6(7):493-5, 2009 Jul - Who cited this? | PubMed ID: 19525957 | Fulltext

Extensive genomic copy number variation in embryonic stem cells.

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Liang Q, Conte N, Skarnes WC, and Bradley A

Proceedings of the National Academy of Sciences of the United States of America 105(45):17453-6, 2008 Nov 11 - Who cited this? | PubMed ID: 18988746 | Fulltext

ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a.

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Gao X, Tate P, Hu P, Tjian R, Skarnes WC, and Wang Z

Proceedings of the National Academy of Sciences of the United States of America, 2008 Apr 30 - Who cited this? | PubMed ID: 18448678 | Fulltext

Gene trapping in mouse embryonic stem cells.

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Brennan J and Skarnes WC

Methods in molecular biology (Clifton, N.J.) 461:133-48, 2008 - Who cited this? | PubMed ID: 19030794 | Fulltext

Modeling insertional mutagenesis using gene length and expression in murine embryonic stem cells.

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Nord AS, Vranizan K, Tingley W, Zambon AC, Hanspers K, Fong LG, Hu Y, Bacchetti P, Ferrin TE, Babbitt PC, Doniger SW, Skarnes WC, Young SG, and Conklin BR

PLoS ONE 2(7), 2007 - Who cited this? | PubMed ID: 17637833 | Fulltext

The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse.

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Nord AS, Chang PJ, Conklin BR, Cox AV, Harper CA, Hicks GG, Huang CC, Johns SJ, Kawamoto M, Liu S, Meng EC, Morris JH, Rossant J, Ruiz P, Skarnes WC, Soriano P,

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Nucleic acids research 34(Database issue):D642-8, 2006 Jan 1 - Who cited this? | PubMed ID: 16381950 | Fulltext

Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition.

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Reiter JF and Skarnes WC

Genes & development 20(1):22-7, 2006 Jan 1 - Who cited this? | PubMed ID: 16357211 | Fulltext

Two ways to trap a gene in mice.

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Skarnes WC

Proceedings of the National Academy of Sciences of the United States of America 102(37):13001-2, 2005 Sep 13 - Who cited this? | PubMed ID: 16150712 | Fulltext

JAM-A expression during embryonic development.

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Parris JJ, Cooke VG, Skarnes WC, Duncan MK, and Naik UP

Developmental dynamics : an official publication of the American Association of Anatomists 233(4):1517-24, 2005 Aug - Who cited this? | PubMed ID: 15977176 | Fulltext

Endoplasmic reticulum stress induction of the Grp78/BiP promoter: activating mechanisms mediated by YY1 and its interactive chromatin modifiers.

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Baumeister P, Luo S, Skarnes WC, Sui G, Seto E, Shi Y, and Lee AS

Molecular and cellular biology 25(11):4529, 2005 Jun - Who cited this? | PubMed ID: 15899857 | Fulltext

Beta1,3-N-acetylglucosaminyltransferase 1 glycosylation is required for axon pathfinding by olfactory sensory neurons.

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Henion TR, Raitcheva D, Grosholz R, Biellmann F, Skarnes WC, Hennet T, and Schwarting GA

The Journal of neuroscience : the official journal of the Society for Neuroscience 25(8):1894-903, 2005 Feb 23 - Who cited this? | PubMed ID: 15728829 | Fulltext

The Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic development.

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Ren J, Shi M, Liu R, Yang QH, Johnson T, Skarnes WC, and Du C

Proceedings of the National Academy of Sciences of the United States of America 102(3):565-70, 2005 Jan 18 - Who cited this? | PubMed ID: 15640352 | Fulltext

Polybromo protein BAF180 functions in mammalian cardiac chamber maturation.

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Wang Z, Zhai W, Richardson JA, Olson EN, Meneses JJ, Firpo MT, Kang C, Skarnes WC, and Tjian R

Genes & development 18(24):3106-16, 2004 Dec 15 - Who cited this? | PubMed ID: 15601824 | Fulltext

The knockout mouse project.

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Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, Koller BH,

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Nature genetics 36(9):921-4, 2004 Sep - Who cited this? | PubMed ID: 15340423 | Fulltext

Embryonic fibroblasts with a gene trap mutation in Ext1 produce short heparan sulfate chains.

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Yamada S, Busse M, Ueno M, Kelly OG, Skarnes WC, Sugahara K, and Kusche-Gullberg M

The Journal of biological chemistry 279(31):32134-41, 2004 Jul 30 - Who cited this? | PubMed ID: 15161920 | Fulltext

The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice.

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Kelly OG, Pinson KI, and Skarnes WC

Development (Cambridge, England) 131(12):2803, 2004 Jun - Who cited this? | PubMed ID: 15142971 | Fulltext

A public gene trap resource for mouse functional genomics.

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Skarnes WC, von Melchner H, Wurst W, Hicks G, Nord AS, Cox T, Young SG, Ruiz P, Soriano P, Tessier-Lavigne M, Conklin BR, Stanford WL, Rossant J, and International Gene Trap Consortium

Nature genetics 36(6):543-4, 2004 Jun - Who cited this? | PubMed ID: 15167922 | Fulltext

ATP-citrate lyase deficiency in the mouse.

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Beigneux AP, Kosinski C, Gavino B, Horton JD, Skarnes WC, and Young SG

The Journal of biological chemistry 279(10):9557-64, 2004 Mar 5 - Who cited this? | PubMed ID: 14662765 | Fulltext

Expression of laminin chains by central neurons: analysis with gene and protein trapping techniques.

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Yin Y, Kikkawa Y, Mudd JL, Skarnes WC, Sanes JR, and Miner JH

Genesis (New York, N.Y. : 2000) 36(2):114-27, 2003 Jun - Who cited this? | PubMed ID: 12820173 | Fulltext

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.

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Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, and Ferrin TE

Nucleic acids research 31(1):278-81, 2003 Jan 1 - Who cited this? | PubMed ID: 12520002 | Fulltext

Defining the importance of phosphatidylserine synthase 2 in mice.

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Bergo MO, Gavino BJ, Steenbergen R, Sturbois B, Parlow AF, Sanan DA, Skarnes WC, Vance JE, and Young SG

The Journal of biological chemistry 277(49):47701-8, 2002 Dec 6 - Who cited this? | PubMed ID: 12361952 | Fulltext

Gene structure and functional analysis of the mouse nidogen-2 gene: nidogen-2 is not essential for basement membrane formation in mice.

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Schymeinsky J, Nedbal S, Miosge N, Pöschl E, Rao C, Beier DR, Skarnes WC, Timpl R, and Bader BL

Molecular and cellular biology 22(19):6820-30, 2002 Oct - Who cited this? | PubMed ID: 12215539 | Fulltext

Maternal effect for DNA mismatch repair in the mouse.

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Gurtu VE, Verma S, Grossmann AH, Liskay RM, Skarnes WC, and Baker SM

Genetics 160(1):271-7, 2002 Jan - Who cited this? | PubMed ID: 11805062 | Fulltext

Functional analysis of secreted and transmembrane proteins critical to mouse development.

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Mitchell KJ, Pinson KI, Kelly OG, Brennan J, Zupicich J, Scherz P, Leighton PA, Goodrich LV, Lu X, Avery BJ, Tate P, Dill K, Pangilinan E, Wakenight P, Tessier-Lavigne M, and Skarnes WC

Nature genetics 28(3):241-9, 2001 Jul - Who cited this? | PubMed ID: 11431694 | Fulltext

Defining brain wiring patterns and mechanisms through gene trapping in mice.

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Leighton PA, Mitchell KJ, Goodrich LV, Lu X, Pinson K, Scherz P, Skarnes WC, and Tessier-Lavigne M

Nature 410(6825):174, 2001 Mar 8 - Who cited this? | PubMed ID: 11242070 | Fulltext

Sequence interpretation. Functional annotation of mouse genome sequences.

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Nadeau JH, Balling R, Barsh G, Beier D, Brown SD, Bucan M, Camper S, Carlson G, Copeland N, Eppig J, Fletcher C, Frankel WN, Ganten D, Goldowitz D, Goodnow C, Guenet JL,

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Science (New York, N.Y.) 291(5507):1251-5, 2001 Feb 16 - Who cited this? | PubMed ID: 11233449 | Fulltext

Mutation and analysis of Dan, the founding member of the Dan family of transforming growth factor beta antagonists.

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Dionne MS, Skarnes WC, and Harland RM

Molecular and cellular biology 21(2):636-43, 2001 Jan - Who cited this? | PubMed ID: 11134349 | Fulltext

Computational prediction of membrane-tethered transcription factors.

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Zupicich J, Brenner SE, and Skarnes WC

Genome biology 2(12):RESEARCH0050, 2001 - Who cited this? | PubMed ID: 11790253 | Fulltext

Agrin isoforms with distinct amino termini: differential expression, localization, and function.

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Burgess RW, Skarnes WC, and Sanes JR

The Journal of cell biology 151(1):41-52, 2000 Oct 2 - Who cited this? | PubMed ID: 11018052 | Fulltext

An LDL-receptor-related protein mediates Wnt signalling in mice.

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Pinson KI, Brennan J, Monkley S, Avery BJ, and Skarnes WC

Nature 407(6803):535-8, 2000 Sep 28 - Who cited this? | PubMed ID: 11029008 | Fulltext

glypican-3 controls cellular responses to Bmp4 in limb patterning and skeletal development.

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Paine-Saunders S, Viviano BL, Zupicich J, Skarnes WC, and Saunders S

Developmental biology 225(1):179-87, 2000 Sep 1 - Who cited this? | PubMed ID: 10964473 | Fulltext

Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections.

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Chen H, Bagri A, Zupicich JA, Zou Y, Stoeckli E, Pleasure SJ, Lowenstein DH, Skarnes WC, Chédotal A, and Tessier-Lavigne M

Neuron 25(1):43-56, 2000 Jan - Who cited this? | PubMed ID: 10707971 | Fulltext

Gene trapping methods for the identification and functional analysis of cell surface proteins in mice.

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Skarnes WC

Methods in enzymology 328:592-615, 2000 - Who cited this? | PubMed ID: 11075368 | Fulltext

Gene trapping in mouse embryonic stem cells.

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Brennan J and Skarnes WC

Methods in molecular biology (Clifton, N.J.) 97:123-38, 1999 - Who cited this? | PubMed ID: 10443362 | Fulltext

Capturing novel mouse genes encoding chromosomal and other nuclear proteins.

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Tate P, Lee M, Tweedie S, Skarnes WC, and Bickmore WA

Journal of cell science 111 ( Pt 17):2575, 1998 Sep - Who cited this? | PubMed ID: 9701556 | Fulltext

Gene-trapping to identify and analyze genes expressed in the mouse hippocampus.

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Steel M, Moss J, Clark KA, Kearns IR, Davies CH, Morris RG, Skarnes WC, and Lathe R

Hippocampus 8(5):444-57, 1998 - Who cited this? | PubMed ID: 9825957 | Fulltext

Rapid sequence analysis of gene trap integrations to generate a resource of insertional mutations in mice.

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Townley DJ, Avery BJ, Rosen B, and Skarnes WC

Genome research 7(3):293-8, 1997 Mar - Who cited this? | PubMed ID: 9074932 | Fulltext

Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system.

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Serafini T, Colamarino SA, Leonardo ED, Wang H, Beddington R, Skarnes WC, and Tessier-Lavigne M

Cell 87(6):1001-14, 1996 Dec 13 - Who cited this? | PubMed ID: 8978605 | Fulltext

Capturing genes encoding membrane and secreted proteins important for mouse development.

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Skarnes WC, Moss JE, Hurtley SM, and Beddington RS

Proceedings of the National Academy of Sciences of the United States of America 92(14):6592, 1995 Jul 3 - Who cited this? | PubMed ID: 7604039 | Fulltext

The T gene is necessary for normal mesodermal morphogenetic cell movements during gastrulation.

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Wilson V, Manson L, Skarnes WC, and Beddington RS

Development (Cambridge, England) 121(3):877-86, 1995 Mar - Who cited this? | PubMed ID: 7720590 | Fulltext

The identification of new genes: gene trapping in transgenic mice.

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Skarnes WC

Current opinion in biotechnology 4(6):684-9, 1993 Dec - Who cited this? | PubMed ID: 7764465 | Fulltext

A gene trap approach in mouse embryonic stem cells: the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice.

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Skarnes WC, Auerbach BA, and Joyner AL

Genes & development 6(6):903-18, 1992 Jun - Who cited this? | PubMed ID: 1592261 | Fulltext

The gene trap approach in embryonic stem cells: the potential for genetic screens in mice.

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Joyner AL, Auerbach A, and Skarnes WC

Ciba Foundation symposium 165:277-88; discussion 288-97, 1992 - Who cited this? | PubMed ID: 1516474 | Fulltext

RNA polymerase II pauses in vitro, but does not terminate, at discrete sites in promoter-proximal regions on polyomavirus transcription complexes.

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Skarnes WC and Acheson NH

Virology 182(1):54-60, 1991 May - Who cited this? | PubMed ID: 1850913 | Fulltext

Entrapment vectors: a new tool for mammalian genetics.

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Skarnes WC

Bio/technology (Nature Publishing Company) 8(9):827-31, 1990 Sep - Who cited this? | PubMed ID: 1366793 | Fulltext

Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes.

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Gossler A, Joyner AL, Rossant J, and Skarnes WC

Science (New York, N.Y.) 244(4903):463-5, 1989 Apr 28 - Who cited this? | PubMed ID: 2497519 | Fulltext

Production of a mutation in mouse En-2 gene by homologous recombination in embryonic stem cells.

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Joyner AL, Skarnes WC, and Rossant J

Nature 338(6211):153-6, 1989 Mar 9 - Who cited this? | PubMed ID: 2563902 | Fulltext

Nerve growth factor regulates gene expression by several distinct mechanisms.

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Cho KO, Skarnes WC, Minsk B, Palmieri S, Jackson-Grusby L, and Wagner JA

Molecular and cellular biology 9(1):135-43, 1989 Jan - Who cited this? | PubMed ID: 2538715 | Fulltext

RNA polymerases stall and/or prematurely terminate nearby both early and late promoters on polyomavirus DNA.

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Skarnes WC, Tessier DC, and Acheson NH

Journal of molecular biology 203(1):153-71, 1988 Sep 5 - Who cited this? | PubMed ID: 2846852 | Fulltext

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