Papers authored by Siu WY

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Polyploidization increases the sensitivity to DNA-damaging agents in mammalian cells.
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Hau PM, Siu WY, Wong N, Lai PB, and Poon RY
FEBS letters 580(19):4727, 2006 Aug 21 - Who cited this? | PubMed ID: 16887121 | Fulltext
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Stalled replication induces p53 accumulation through distinct mechanisms from DNA damage checkpoint pathways.
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Ho CC, Siu WY, Lau A, Chan WM, Arooz T, and Poon RY
Cancer research 66(4):2233-41, 2006 Feb 15 - Who cited this? | PubMed ID: 16489026 | Fulltext
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Ubiquitination of p53 at multiple sites in the DNA-binding domain.
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Chan WM, Mak MC, Fung TK, Lau A, Siu WY, and Poon RY
Molecular cancer research : MCR 4(1):15-25, 2006 Jan - Who cited this? | PubMed ID: 16446403 | Fulltext
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The relative contribution of CHK1 and CHK2 to Adriamycin-induced checkpoint.
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Ho CC, Siu WY, Chow JP, Lau A, Arooz T, Tong HY, Ng IO, and Poon RY
Experimental cell research 304(1):1-15, 2005 Mar 10 - Who cited this? | PubMed ID: 15707569 | Fulltext
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Topoisomerase poisons differentially activate DNA damage checkpoints through ataxia-telangiectasia mutated-dependent and -independent mechanisms.
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Siu WY, Lau A, Arooz T, Chow JP, Ho HT, and Poon RY
Molecular cancer therapeutics 3(5):621-32, 2004 May - Who cited this? | PubMed ID: 15141020 | Fulltext
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How many mutant p53 molecules are needed to inactivate a tetramer?.
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Chan WM, Siu WY, Lau A, and Poon RY
Molecular and cellular biology 24(8):3536-51, 2004 Apr - Who cited this? | PubMed ID: 15060172 | Fulltext
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Differential mode of regulation of the checkpoint kinases CHK1 and CHK2 by their regulatory domains.
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Ng CP, Lee HC, Ho CW, Arooz T, Siu WY, Lau A, and Poon RY
The Journal of biological chemistry 279(10):8808-19, 2004 Mar 5 - Who cited this? | PubMed ID: 14681223 | Fulltext
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ING1b decreases cell proliferation through p53-dependent and -independent mechanisms.
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Tsang FC, Po LS, Leung KM, Lau A, Siu WY, and Poon RY
FEBS letters 553(3):277, 2003 Oct 23 - Who cited this? | PubMed ID: 14572637 | Fulltext
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Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints.
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Chow JP, Siu WY, Ho HT, Ma KH, Ho CC, and Poon RY
The Journal of biological chemistry 278(42):40815-28, 2003 Oct 17 - Who cited this? | PubMed ID: 12912980 | Fulltext
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DNA damage during the spindle-assembly checkpoint degrades CDC25A, inhibits cyclin-CDC2 complexes, and reverses cells to interphase.
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Chow JP, Siu WY, Fung TK, Chan WM, Lau A, Arooz T, Ng CP, Yamashita K, and Poon RY
Molecular biology of the cell 14(10):3989-4002, 2003 Oct - Who cited this? | PubMed ID: 14517313 | Fulltext
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Cyclin F is degraded during G2-M by mechanisms fundamentally different from other cyclins.
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Fung TK, Siu WY, Yam CH, Lau A, and Poon RY
The Journal of biological chemistry 277(38):35140-9, 2002 Sep 20 - Who cited this? | PubMed ID: 12122006 | Fulltext
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The candidate tumor suppressor ING1b can stabilize p53 by disrupting the regulation of p53 by MDM2.
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Leung KM, Po LS, Tsang FC, Siu WY, Lau A, Ho HT, and Poon RY
Cancer research 62(17):4890, 2002 Sep 1 - Who cited this? | PubMed ID: 12208736 | Fulltext
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MDM2 and MDMX can interact differently with ARF and members of the p53 family.
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Wang X, Arooz T, Siu WY, Chiu CH, Lau A, Yamashita K, and Poon RY
FEBS letters 490(3):202-8, 2001 Feb 16 - Who cited this? | PubMed ID: 11223036 | Fulltext
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Cleavage of cyclin A at R70/R71 by the bacterial protease OmpT.
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Yam CH, Siu WY, Kaganovich D, Ruderman JV, and Poon RY
Proceedings of the National Academy of Sciences of the United States of America 98(2):497, 2001 Jan 16 - Who cited this? | PubMed ID: 11136238 | Fulltext
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On the concentrations of cyclins and cyclin-dependent kinases in extracts of cultured human cells.
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Arooz T, Yam CH, Siu WY, Lau A, Li KK, and Poon RY
Biochemistry 39(31):9494, 2000 Aug 8 - Who cited this? | PubMed ID: 10924145 | Fulltext
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Degradation of cyclin A does not require its phosphorylation by CDC2 and cyclin-dependent kinase 2.
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Yam CH, Siu WY, Lau A, and Poon RY
The Journal of biological chemistry 275(5):3158-67, 2000 Feb 4 - Who cited this? | PubMed ID: 10652300 | Fulltext
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G1 versus G2 cell cycle arrest after adriamycin-induced damage in mouse Swiss3T3 cells.
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Siu WY, Yam CH, and Poon RY
FEBS letters 461(3):299-305, 1999 Nov 19 - Who cited this? | PubMed ID: 10567715 | Fulltext
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MDM2 and MDMX inhibit the transcriptional activity of ectopically expressed SMAD proteins.
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Yam CH, Siu WY, Arooz T, Chiu CH, Lau A, Wang XQ, and Poon RY
Cancer research 59(20):5075-8, 1999 Oct 15 - Who cited this? | PubMed ID: 10537276 | Fulltext
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Differential responses of proliferating versus quiescent cells to adriamycin.
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Siu WY, Arooz T, and Poon RY
Experimental cell research 250(1):131-41, 1999 Jul 10 - Who cited this? | PubMed ID: 10388527 | Fulltext
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Regulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2.
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Yam CH, Ng RW, Siu WY, Lau AW, and Poon RY
Molecular and cellular biology 19(1):635-45, 1999 Jan - Who cited this? | PubMed ID: 9858587 | Fulltext
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MDM2 and MDMX bind and stabilize the p53-related protein p73.
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Ongkeko WM, Wang XQ, Siu WY, Lau AW, Yamashita K, Harris AL, Cox LS, and Poon RY
Current biology : CB 9(15):829-32, 1999 - Who cited this? | PubMed ID: 10469568 | Fulltext
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Supplementation with vitamins C and E enhances cytokine production by peripheral blood mononuclear cells in healthy adults.
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Jeng KC, Yang CS, Siu WY, Tsai YS, Liao WJ, and Kuo JS
The American journal of clinical nutrition 64(6):960-5, 1996 Dec - Who cited this? | PubMed ID: 8942423 | Fulltext
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