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Papers authored by Sirard JC

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Toll-like receptor 2 is critical for induction of Reg3{beta} expression and intestinal clearance of Yersinia pseudotuberculosis.

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Dessein R, Gironella M, Vignal C, Peyrin-Biroulet L, Sokol H, Secher T, Lacas-Gervais S, Gratadoux JJ, Lafont F, Dagorn JC, Ryffel B, Akira S, Langella P, Nùñez G, Sirard JC, Iovanna J,

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Gut 58(6):771-6, 2009 Jun - Who cited this? | PubMed ID: 19174417 | Fulltext

Radioresistant cells expressing TLR5 control the respiratory epithelium's innate immune responses to flagellin.

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Janot L, Sirard JC, Secher T, Noulin N, Fick L, Akira S, Uematsu S, Didierlaurent A, Hussell T, Ryffel B, and Erard F

European journal of immunology 39(6):1587-96, 2009 Jun - Who cited this? | PubMed ID: 19424969 | Fulltext

Toll-like receptor 5- and lymphotoxin beta receptor-dependent epithelial Ccl20 expression involves the same NF-kappaB binding site but distinct NF-kappaB pathways and dynamics.

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Sirard JC, Didierlaurent A, Cayet D, Sierro F, and Rumbo M

Biochimica et biophysica acta 1789(5):386-94, 2009 May - Who cited this? | PubMed ID: 19303953 | Fulltext

Deletion of flagellin's hypervariable region abrogates antibody-mediated neutralization and systemic activation of TLR5-dependent immunity.

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Nempont C, Cayet D, Rumbo M, Bompard C, Villeret V, and Sirard JC

Journal of immunology (Baltimore, Md. : 1950) 181(3):2036, 2008 Aug 1 - Who cited this? | PubMed ID: 18641341 | Fulltext

Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection.

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Didierlaurent A, Goulding J, Patel S, Snelgrove R, Low L, Bebien M, Lawrence T, van Rijt LS, Lambrecht BN, Sirard JC, and Hussell T

The Journal of experimental medicine 205(2):323-9, 2008 Feb 18 - Who cited this? | PubMed ID: 18227219 | Fulltext

Nod-like receptors: cytosolic watchdogs for immunity against pathogens.

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Sirard JC, Vignal C, Dessein R, and Chamaillard M

PLoS pathogens 3(12), 2007 Dec 28 - Who cited this? | PubMed ID: 18166077 | Fulltext

Adhesin-dependent binding and uptake of Salmonella enterica serovar Typhimurium by dendritic cells.

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Guo A, Lasaro MA, Sirard JC, Kraehenbühl JP, and Schifferli DM

Microbiology (Reading, England) 153(Pt 4):1059-69, 2007 Apr - Who cited this? | PubMed ID: 17379714 | Fulltext

A key role of dendritic cells in probiotic functionality.

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Foligne B, Zoumpopoulou G, Dewulf J, Ben Younes A, Chareyre F, Sirard JC, Pot B, and Grangette C

PLoS ONE 2(3), 2007 - Who cited this? | PubMed ID: 17375199 | Fulltext

Delayed expansion and contraction of CD8+ T cell response during infection with virulent Salmonella typhimurium.

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Luu RA, Gurnani K, Dudani R, Kammara R, van Faassen H, Sirard JC, Krishnan L, and Sad S

Journal of immunology (Baltimore, Md. : 1950) 177(3):1516-25, 2006 Aug 1 - Who cited this? | PubMed ID: 16849458 | Fulltext

Mucosal interplay among commensal and pathogenic bacteria: lessons from flagellin and Toll-like receptor 5.

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Rumbo M, Nempont C, Kraehenbuhl JP, and Sirard JC

FEBS letters 580(12):2976-84, 2006 May 22 - Who cited this? | PubMed ID: 16650409 | Fulltext

Pathogen-specific TLR signaling in mucosa: mutual contribution of microbial TLR agonists and virulence factors.

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Sirard JC, Bayardo M, and Didierlaurent A

European journal of immunology 36(2):260, 2006 Feb - Who cited this? | PubMed ID: 16453385 | Fulltext

Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo.

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Le Borgne M, Etchart N, Goubier A, Lira SA, Sirard JC, Van Rooijen N, Caux C, Aït-Yahia S, Vicari A, Kaiserlian D, and Dubois B

Immunity 24(2):191, 2006 Feb - Who cited this? | PubMed ID: 16473831 | Fulltext

Tollip regulates proinflammatory responses to interleukin-1 and lipopolysaccharide.

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Didierlaurent A, Brissoni B, Velin D, Aebi N, Tardivel A, Käslin E, Sirard JC, Angelov G, Tschopp J, and Burns K

Molecular and cellular biology 26(3):735-42, 2006 Feb - Who cited this? | PubMed ID: 16428431 | Fulltext

Innate and acquired plasticity of the intestinal immune system.

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Didierlaurent A, Simonet M, and Sirard JC

Cellular and molecular life sciences : CMLS 62(12):1285-7, 2005 Jun - Who cited this? | PubMed ID: 15971103 | Fulltext

Polarized distribution of inducible nitric oxide synthase regulates activity in intestinal epithelial cells.

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Rumbo M, Courjault-Gautier F, Sierro F, Sirard JC, and Felley-Bosco E

The FEBS journal 272(2):444-53, 2005 Jan - Who cited this? | PubMed ID: 15654882 | Fulltext

How the gut links innate and adaptive immunity.

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Rumbo M, Anderle P, Didierlaurent A, Sierro F, Debard N, Sirard JC, Finke D, and Kraehenbuhl JP

Annals of the New York Academy of Sciences 1029:16-21, 2004 Dec - Who cited this? | PubMed ID: 15681739 | Fulltext

Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa.

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Ramos HC, Rumbo M, and Sirard JC

Trends in microbiology 12(11):509-17, 2004 Nov - Who cited this? | PubMed ID: 15488392 | Fulltext

Attenuated poxviruses expressing a synthetic HIV protein stimulate HLA-A2-restricted cytotoxic T-cell responses.

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Didierlaurent A, Ramirez JC, Gherardi M, Zimmerli SC, Graf M, Orbea HA, Pantaleo G, Wagner R, Esteban M, Kraehenbuhl JP, and Sirard JC

Vaccine 22(25-26):3395-403, 2004 Sep 3 - Who cited this? | PubMed ID: 15308364 | Fulltext

Flagellin promotes myeloid differentiation factor 88-dependent development of Th2-type response.

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Didierlaurent A, Ferrero I, Otten LA, Dubois B, Reinhardt M, Carlsen H, Blomhoff R, Akira S, Kraehenbuhl JP, and Sirard JC

Journal of immunology (Baltimore, Md. : 1950) 172(11):6922-30, 2004 Jun 1 - Who cited this? | PubMed ID: 15153511 | Fulltext

Interaction of pathogenic bacteria with rabbit appendix M cells: bacterial motility is a key feature in vivo.

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Marchetti M, Sirard JC, Sansonetti P, Pringault E, and Kernéis S

Microbes and infection / Institut Pasteur 6(6):521-8, 2004 May - Who cited this? | PubMed ID: 15158184 | Fulltext

Dendritic cells: the host Achille's heel for mucosal pathogens?.

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Niedergang F, Didierlaurent A, Kraehenbuhl JP, and Sirard JC

Trends in microbiology 12(2):79-88, 2004 Feb - Who cited this? | PubMed ID: 15036324 | Fulltext

Role of Toll-like receptors in costimulating cytotoxic T cell responses.

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Schwarz K, Storni T, Manolova V, Didierlaurent A, Sirard JC, Röthlisberger P, and Bachmann MF

European journal of immunology 33(6):1465-70, 2003 Jun - Who cited this? | PubMed ID: 12778463 | Fulltext

How the gut senses its content.

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Didierlaurent A, Sirard JC, Kraehenbuhl JP, and Neutra MR

Cellular microbiology 4(2):61-72, 2002 Feb - Who cited this? | PubMed ID: 11896763 | Fulltext

Flagellin stimulation of intestinal epithelial cells triggers CCL20-mediated migration of dendritic cells.

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Sierro F, Dubois B, Coste A, Kaiserlian D, Kraehenbuhl JP, and Sirard JC

Proceedings of the National Academy of Sciences of the United States of America 98(24):13722-7, 2001 Nov 20 - Who cited this? | PubMed ID: 11717433 | Fulltext

Nasal immunisation with Salmonella typhimurium producing rotavirus VP2 and VP6 antigens stimulates specific antibody response in serum and milk but fails to protect offspring.

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Coste A, Cohen J, Reinhardt M, Kraehenbuhl JP, and Sirard JC

Vaccine 19(30):4167-74, 2001 Jul 20 - Who cited this? | PubMed ID: 11457542 | Fulltext

Entry and survival of Salmonella typhimurium in dendritic cells and presentation of recombinant antigens do not require macrophage-specific virulence factors.

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Niedergang F, Sirard JC, Blanc CT, and Kraehenbuhl JP

Proceedings of the National Academy of Sciences of the United States of America 97(26):14650, 2000 Dec 19 - Who cited this? | PubMed ID: 11121065 | Fulltext

Nasal immunization of mice with virus-like particles protects offspring against rotavirus diarrhea.

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Coste A, Sirard JC, Johansen K, Cohen J, and Kraehenbuhl JP

Journal of virology 74(19):8966-71, 2000 Oct - Who cited this? | PubMed ID: 10982340 | Fulltext

Protective antigen-mediated antibody response against a heterologous protein produced in vivo by Bacillus anthracis.

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Brossier F, Weber-Levy M, Mock M, and Sirard JC

Infection and immunity 68(10):5731-4, 2000 Oct - Who cited this? | PubMed ID: 10992478 | Fulltext

Characterization of a plasmid region involved in Bacillus anthracis toxin production and pathogenesis.

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Sirard JC, Guidi-Rontani C, Fouet A, and Mock M

International journal of medical microbiology : IJMM 290(4-5):313-6, 2000 Oct - Who cited this? | PubMed ID: 11111904 | Fulltext

Role of toxin functional domains in anthrax pathogenesis.

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Brossier F, Weber-Levy M, Mock M, and Sirard JC

Infection and immunity 68(4):1781, 2000 Apr - Who cited this? | PubMed ID: 10722564 | Fulltext

Live attenuated Salmonella: a paradigm of mucosal vaccines.

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Sirard JC, Niedergang F, and Kraehenbuhl JP

Immunological reviews 171:5-26, 1999 Oct - Who cited this? | PubMed ID: 10582163 | Fulltext

Antigen delivery by attenuated Bacillus anthracis: new prospects in veterinary vaccines.

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Brossier F, Mock M, and Sirard JC

Journal of applied microbiology 87(2):298-302, 1999 Aug - Who cited this? | PubMed ID: 10475973 | Fulltext

Identification and characterization of a germination operon on the virulence plasmid pXO1 of Bacillus anthracis.

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Guidi-Rontani C, Pereira Y, Ruffie S, Sirard JC, Weber-Levy M, and Mock M

Molecular microbiology 33(2):407-14, 1999 Jul - Who cited this? | PubMed ID: 10411756 | Fulltext

Functional analysis of the carboxy-terminal domain of Bacillus anthracis protective antigen.

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Brossier F, Sirard JC, Guidi-Rontani C, Duflot E, and Mock M

Infection and immunity 67(2):964-7, 1999 Feb - Who cited this? | PubMed ID: 9916116 | Fulltext

Intracytoplasmic delivery of listeriolysin O by a vaccinal strain of Bacillus anthracis induces CD8-mediated protection against Listeria monocytogenes.

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Sirard JC, Fayolle C, de Chastellier C, Mock M, Leclerc C, and Berche P

Journal of immunology (Baltimore, Md. : 1950) 159(9):4435-43, 1997 Nov 1 - Who cited this? | PubMed ID: 9379042 | Fulltext

A recombinant Bacillus anthracis strain producing the Clostridium perfringens Ib component induces protection against iota toxins.

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Sirard JC, Weber M, Duflot E, Popoff MR, and Mock M

Infection and immunity 65(6):2029-33, 1997 Jun - Who cited this? | PubMed ID: 9169728 | Fulltext

Protective immunity induced by Bacillus anthracis toxin mutant strains.

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Pezard C, Sirard JC, and Mock M

Advances in experimental medicine and biology 397:69-72, 1996 - Who cited this? | PubMed ID: 8718584 | Fulltext

The atxA gene product activates transcription of the anthrax toxin genes and is essential for virulence.

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Dai Z, Sirard JC, Mock M, and Koehler TM

Molecular microbiology 16(6):1171-81, 1995 Jun - Who cited this? | PubMed ID: 8577251 | Fulltext

Protective immunity induced by Bacillus anthracis toxin-deficient strains.

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Pezard C, Weber M, Sirard JC, Berche P, and Mock M

Infection and immunity 63(4):1369-72, 1995 Apr - Who cited this? | PubMed ID: 7890396 | Fulltext

Characterization of the Bacillus anthracis S-layer: cloning and sequencing of the structural gene.

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Etienne-Toumelin I, Sirard JC, Duflot E, Mock M, and Fouet A

Journal of bacteriology 177(3):614-20, 1995 Feb - Who cited this? | PubMed ID: 7836294 | Fulltext

Molecular tools for the study of transcriptional regulation in Bacillus anthracis.

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Sirard JC, Mock M, and Fouet A

Research in microbiology 146(9):729-37, 1995 - Who cited this? | PubMed ID: 8584795 | Fulltext

The three Bacillus anthracis toxin genes are coordinately regulated by bicarbonate and temperature.

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Sirard JC, Mock M, and Fouet A

Journal of bacteriology 176(16):5188-92, 1994 Aug - Who cited this? | PubMed ID: 8051039 | Fulltext

Bacillus anthracis pXO1 virulence plasmid encodes a type 1 DNA topoisomerase.

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Fouet A, Sirard JC, and Mock M

Molecular microbiology 11(3):471-9, 1994 Feb - Who cited this? | PubMed ID: 8152371 | Fulltext

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