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Papers authored by Simpkins L

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N-Aryl-oxazolidin-2-imine Muscle Selective Androgen Receptor Modulators Enhance Potency through Pharmacophore Reorientation (dagger) ( big up tri, open).

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Nirschl AA, Zou Y, Krystek SR, Sutton JC, Simpkins LM, Lupisella JA, Kuhns JE, Seethala R, Golla R, Sleph PG, Beehler BC, Grover GJ, Egan D, Fura A, Vyas VP, Li YX,

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Journal of medicinal chemistry 52(9):2794-8, 2009 May 14 - Who cited this? | PubMed ID: 19351168 | Fulltext

Pyridine amides as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.

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Wang H, Ruan Z, Li JJ, Simpkins LM, Smirk RA, Wu SC, Hutchins RD, Nirschl DS, Van Kirk K, Cooper CB, Sutton JC, Ma Z, Golla R, Seethala R, Salyan ME, Nayeem A,

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Bioorganic & medicinal chemistry letters 18(11):3168-72, 2008 Jun 1 - Who cited this? | PubMed ID: 18485702 | Fulltext

Potent non-nitrile dipeptidic dipeptidyl peptidase IV inhibitors.

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Simpkins LM, Bolton S, Pi Z, Sutton JC, Kwon C, Zhao G, Magnin DR, Augeri DJ, Gungor T, Rotella DP, Sun Z, Liu Y, Slusarchyk WS, Marcinkeviciene J, Robertson JG, Wang A,

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Bioorganic & medicinal chemistry letters 17(23):6476-80, 2007 Dec 1 - Who cited this? | PubMed ID: 17937986 | Fulltext

Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP).

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Sulsky R, Magnin DR, Huang Y, Simpkins L, Taunk P, Patel M, Zhu Y, Stouch TR, Bassolino-Klimas D, Parker R, Harrity T, Stoffel R, Taylor DS, Lavoie TB, Kish K, Jacobson BL,

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Bioorganic & medicinal chemistry letters 17(12):3511-5, 2007 Jun 15 - Who cited this? | PubMed ID: 17502136 | Fulltext

Diprolyl nitriles as potent dipeptidyl peptidase IV inhibitors.

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Zhao G, Taunk PC, Magnin DR, Simpkins LM, Robl JA, Wang A, Robertson JG, Marcinkeviciene J, Sitkoff DF, Parker RA, Kirby MS, and Hamann LG

Bioorganic & medicinal chemistry letters 15(18):3992-5, 2005 Sep 15 - Who cited this? | PubMed ID: 16046120 | Fulltext

Discovery and preclinical profile of Saxagliptin (BMS-477118): a highly potent, long-acting, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.

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Augeri DJ, Robl JA, Betebenner DA, Magnin DR, Khanna A, Robertson JG, Wang A, Simpkins LM, Taunk P, Huang Q, Han SP, Abboa-Offei B, Cap M, Xin L, Tao L, Tozzo E,

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Journal of medicinal chemistry 48(15):5025-37, 2005 Jul 28 - Who cited this? | PubMed ID: 16033281 | Fulltext

Synthesis of novel potent dipeptidyl peptidase IV inhibitors with enhanced chemical stability: interplay between the N-terminal amino acid alkyl side chain and the cyclopropyl group of alpha-aminoacyl-l-cis-4,5-methanoprolinenitrile-based inhibitors.

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Magnin DR, Robl JA, Sulsky RB, Augeri DJ, Huang Y, Simpkins LM, Taunk PC, Betebenner DA, Robertson JG, Abboa-Offei BE, Wang A, Cap M, Xin L, Tao L, Sitkoff DF, Malley MF,

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Journal of medicinal chemistry 47(10):2587-98, 2004 May 6 - Who cited this? | PubMed ID: 15115400 | Fulltext

What is the worst story of intervention-gone-awry that you know of?.

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Simpkins L

Midwifery today with international midwife(63):8, 67, 2002 - Who cited this? | PubMed ID: 12298396 | Fulltext

A novel series of highly potent benzimidazole-based microsomal triglyceride transfer protein inhibitors.

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Robl JA, Sulsky R, Sun CQ, Simpkins LM, Wang T, Dickson JK, Chen Y, Magnin DR, Taunk P, Slusarchyk WA, Biller SA, Lan SJ, Connolly F, Kunselman LK, Sabrah T, Jamil H,

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Journal of medicinal chemistry 44(6):851-6, 2001 Mar 15 - Who cited this? | PubMed ID: 11300866 | Fulltext

N-formyl hydroxylamine containing dipeptides: generation of a new class of vasopeptidase inhibitors.

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Robl JA, Simpkins LM, and Asaad MM

Bioorganic & medicinal chemistry letters 10(3):257-60, 2000 Feb 7 - Who cited this? | PubMed ID: 10698448 | Fulltext

Herpes zoster and postherpetic neuralgia in the elderly.

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Lee VK and Simpkins L

Geriatric nursing (New York, N.Y.) 21(3):132-5; quiz 136, 2000 - Who cited this? | PubMed ID: 10864692 | Fulltext

Vasopeptidase inhibitors: incorporation of geminal and spirocyclic substituted azepinones in mercaptoacyl dipeptides.

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Robl JA, Sulsky R, Sieber-McMaster E, Ryono DE, Cimarusti MP, Simpkins LM, Karanewsky DS, Chao S, Asaad MM, Seymour AA, Fox M, Smith PL, and Trippodo NC

Journal of medicinal chemistry 42(2):305-11, 1999 Jan 28 - Who cited this? | PubMed ID: 9925736 | Fulltext

Taking care of your skin as you age.

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Simpkins LH

Lippincott's primary care practice 3(2):179-81, 1999 - Who cited this? | PubMed ID: 10426062 | Fulltext

Depression.

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Simpkins LH

Lippincott's primary care practice 3(2):182-4, 1999 - Who cited this? | PubMed ID: 10426063 | Fulltext

An MTP inhibitor that normalizes atherogenic lipoprotein levels in WHHL rabbits.

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Wetterau JR, Gregg RE, Harrity TW, Arbeeny C, Cap M, Connolly F, Chu CH, George RJ, Gordon DA, Jamil H, Jolibois KG, Kunselman LK, Lan SJ, Maccagnan TJ, Ricci B, Yan M,

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Science (New York, N.Y.) 282(5389):751-4, 1998 Oct 23 - Who cited this? | PubMed ID: 9784135 | Fulltext

Dual metalloprotease inhibitors: mercaptoacetyl-based fused heterocyclic dipeptide mimetics as inhibitors of angiotensin-converting enzyme and neutral endopeptidase.

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Robl JA, Sun CQ, Stevenson J, Ryono DE, Simpkins LM, Cimarusti MP, Dejneka T, Slusarchyk WA, Chao S, Stratton L, Misra RN, Bednarz MS, Asaad MM, Cheung HS, Abboa-Offei BE, Smith PL,

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Journal of medicinal chemistry 40(11):1570-7, 1997 May 23 - Who cited this? | PubMed ID: 9171867 | Fulltext

Dual metalloprotease inhibitors. 6. Incorporation of bicyclic and substituted monocyclic azepinones as dipeptide surrogates in angiotensin-converting enzyme/neutral endopeptidase inhibitors.

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Robl JA, Cimarusti MP, Simpkins LM, Brown B, Ryono DE, Bird JE, Asaad MM, Schaeffer TR, and Trippodo NC

Journal of medicinal chemistry 39(2):494-502, 1996 Jan 19 - Who cited this? | PubMed ID: 8558518 | Fulltext

Influence of tryptophan residues on melittin's hemolytic activity.

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Blondelle SE, Simpkins LR, Pérez-Payá E, and Houghten RA

Biochimica et biophysica acta 1202(2):331-6, 1993 Oct 6 - Who cited this? | PubMed ID: 8399397 | Fulltext

The effects of elastic tights on the post-exercise response.

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Berry MJ, Bailey SP, Simpkins LS, and TeWinkle JA

Canadian journal of sport sciences = Journal canadien des sciences du sport 15(4):244-8, 1990 Dec - Who cited this? | PubMed ID: 2272006 | Fulltext

Phosphorus-containing inhibitors of HMG-CoA reductase. 1. 4-[(2-arylethyl)hydroxyphosphinyl]-3-hydroxy-butanoic acids: a new class of cell-selective inhibitors of cholesterol biosynthesis.

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Karanewsky DS, Badia MC, Ciosek CP, Robl JA, Sofia MJ, Simpkins LM, DeLange B, Harrity TW, Biller SA, and Gordon EM

Journal of medicinal chemistry 33(11):2952-6, 1990 Nov - Who cited this? | PubMed ID: 2231594 | Fulltext

1-Acyltriazoles as antiinflammatory agents.

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Wade PC, Vogt BR, Kissick TP, Simpkins LM, Palmer DM, and Millonig RC

Journal of medicinal chemistry 25(3):331-3, 1982 Mar - Who cited this? | PubMed ID: 6461764 | Fulltext

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