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Papers authored by Shitara K

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Growth inhibition of AML cells with specific chromosome abnormalities by monoclonal antibodies to receptors for vascular endothelial growth factor.

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Imai N, Miwa H, Shikami M, Suganuma K, Gotoh M, Hiramatsu A, Wakabayashi M, Watarai M, Hanamura I, Imamura A, Mihara H, Shitara K, Shibuya M, and Nitta M

Leukemia research 33(12):1650-7, 2009 Dec - Who cited this? | PubMed ID: 19342098 | Fulltext

Association of prostate stem cell antigen gene polymorphisms with the risk of stomach cancer in Japanese.

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Matsuo K, Tajima K, Suzuki T, Kawase T, Watanabe M, Shitara K, Misawa K, Ito S, Sawaki A, Muro K, Nakamura T, Yamao K, Yamamura Y, Hamajima N, Hiraki A, and Tanaka H

International journal of cancer. Journal international du cancer 125(8):1961-4, 2009 Oct 15 - Who cited this? | PubMed ID: 19582881 | Fulltext

Engineered therapeutic antibodies with improved effector functions.

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Kubota T, Niwa R, Satoh M, Akinaga S, Shitara K, and Hanai N

Cancer science 100(9):1566-72, 2009 Sep - Who cited this? | PubMed ID: 19538497 | Fulltext

Neutropaenia as a prognostic factor in metastatic colorectal cancer patients undergoing chemotherapy with first-line FOLFOX.

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Shitara K, Matsuo K, Takahari D, Yokota T, Inaba Y, Yamaura H, Sato Y, Najima M, Ura T, and Muro K

European journal of cancer (Oxford, England : 1990) 45(10):1757-63, 2009 Jul - Who cited this? | PubMed ID: 19217278 | Fulltext

Cetuximab for patients with colon cancer and hepatic metastasis complicated by liver dysfunction and icterus.

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Shitara K, Yokota T, and Utsunomiya S

Gastrointestinal cancer research 3(4):171-2, 2009 Jul - Who cited this? | PubMed ID: 19742145 | Fulltext

[Molecular targeted therapy in colorectal cancer and its resistance.].

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Shitara K and Muro K

Gan to kagaku ryoho. Cancer & chemotherapy 36(4):557-66, 2009 Apr - Who cited this? | PubMed ID: 19381027 | Fulltext

Nonfucosylated rituximab potentiates human neutrophil phagocytosis through its high binding for FcgammaRIIIb and MHC class II expression on the phagocytotic neutrophils.

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Shibata-Koyama M, Iida S, Misaka H, Mori K, Yano K, Shitara K, and Satoh M

Experimental hematology 37(3):309-21, 2009 Mar - Who cited this? | PubMed ID: 19218011 | Fulltext

Chemoradiotherapy for treatment of esophageal cancer in Japan: current status and perspectives.

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Shitara K and Muro K

Gastrointestinal cancer research 3(2):66-72, 2009 Mar - Who cited this? | PubMed ID: 19461908 | Fulltext

The N-linked oligosaccharide at Fc{gamma}RIIIa Asn-45: an inhibitory element for high Fc{gamma}RIIIa binding affinity to IgG glycoforms lacking core fucosylation.

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Shibata-Koyama M, Iida S, Okazaki A, Mori K, Kitajima-Miyama K, Saitou S, Kakita S, Kanda Y, Shitara K, Kato K, and Satoh M

Glycobiology 19(2):126-34, 2009 Feb - Who cited this? | PubMed ID: 18952826 | Fulltext

[A Case Report-Gastric Stenosis Due to Primary Gastric Malignant Lymphoma after Administration of R-CHOP.].

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Muto O, Munakata M, Shitara K, Sasaki S, Shimaya S, Sato K, Kasai M, Wada R, Kawamura S, and Sakata Y

Gan to kagaku ryoho. Cancer & chemotherapy 36(2):283-5, 2009 Feb - Who cited this? | PubMed ID: 19223746 | Fulltext

Potelligent antibodies as next generation therapeutic antibodies.

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Shitara K

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 129(1):3-9, 2009 Jan - Who cited this? | PubMed ID: 19122430 | Fulltext

Two mechanisms of the enhanced antibody-dependent cellular cytotoxicity (ADCC) efficacy of non-fucosylated therapeutic antibodies in human blood.

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Iida S, Kuni-Kamochi R, Mori K, Misaka H, Inoue M, Okazaki A, Shitara K, and Satoh M

BMC cancer 9:58, 2009 - Who cited this? | PubMed ID: 19226457 | Fulltext

Chemotherapy for gastric cancer that recurs after adjuvant chemotherapy with S-1.

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Shitara K, Muro K, Ura T, Takahari D, Yokota T, Sawaki A, Kawai H, Ito S, and Yamamura Y

Japanese journal of clinical oncology 38(11):786-9, 2008 Nov - Who cited this? | PubMed ID: 18820010 | Fulltext

Mouse-Human Chimeric Anti-Tn IgG1 Induced Anti-tumor Activity against Jurkat Cells in Vitro and in Vivo.

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Ando H, Matsushita T, Wakitani M, Sato T, Kodama-Nishida S, Shibata K, Shitara K, and Ohta S

Biological & pharmaceutical bulletin 31(9):1739, 2008 Sep - Who cited this? | PubMed ID: 18758069 | Fulltext

Pilot Study of Combination Chemotherapy Using Irinotecan plus S-1 for Metastatic Pancreatic Cancer.

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Shitara K, Komatsu Y, Yuki S, Munakata M, Muto O, Shimaya S, and Sakata Y

Oncology 75(1-2):67, 2008 Aug 28 - Who cited this? | PubMed ID: 18753799 | Fulltext

Metastatic rectal cancer responding to third-line therapy employing bevacizumab after failure of oxaliplatin and irinotecan: case report.

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Shitara K, Munakata M, Muto O, and Sakata Y

Japanese journal of clinical oncology 38(7):493-6, 2008 Jul - Who cited this? | PubMed ID: 18567598 | Fulltext

A case of advanced breast cancer associated with development of liver atrophy with progressive liver failure during treatment.

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Shitara K, Nakamura K, Kasai M, Munakata M, Muto O, Kazaana K, and Sakata Y

Gan to kagaku ryoho. Cancer & chemotherapy 35(6):983, 2008 Jun - Who cited this? | PubMed ID: 18633229 | Fulltext

Engineered Antibodies of IgG1/IgG3 Mixed Isotype with Enhanced Cytotoxic Activities.

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Natsume A, In M, Takamura H, Nakagawa T, Shimizu Y, Kitajima K, Wakitani M, Ohta S, Satoh M, Shitara K, and Niwa R

Cancer research 68(10):3863-72, 2008 May 15 - Who cited this? | PubMed ID: 18483271 | Fulltext

A neutralizing anti-fibroblast growth factor (FGF) 8 monoclonal antibody shows anti-tumor activity against FGF8b-expressing LNCaP xenografts in androgen-dependent and -independent conditions.

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Maruyama-Takahashi K, Shimada N, Imada T, Maekawa-Tokuda Y, Ishii T, Ouchi J, Kusaka H, Miyaji H, Akinaga S, Tanaka A, and Shitara K

The Prostate 68(6):640-50, 2008 May 1 - Who cited this? | PubMed ID: 18213631 | Fulltext

Hepatic arterial infusion of mitomycin C with degradable starch microspheres for unresectable intrahepatic cholangiocarcinoma.

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Shitara K, Ikami I, Munakata M, Muto O, and Sakata Y

Clinical oncology (Royal College of Radiologists (Great Britain)) 20(3):241-6, 2008 Apr - Who cited this? | PubMed ID: 18222071 | Fulltext

Cryptic fragment alpha4 LG4-5 derived from laminin alpha4 chain inhibits de novo adipogenesis by modulating the effect of fibroblast growth factor-2.

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Yamashita H, Goto C, Tajima R, Koparal AT, Kobori M, Ohki Y, Shitara K, Narita R, Toriyama K, Torii S, Niimi T, and Kitagawa Y

Development, growth & differentiation 50(2):97-107, 2008 Feb - Who cited this? | PubMed ID: 18067585 | Fulltext

Prolongation of survival and improvement in performance status following palliative chemotherapy in gastrointestinal cancer patients with a poor performance status.

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Shitara K, Munakata M, Kasai M, Muto O, and Sakata Y

Oncology 74(3-4):135-42, 2008 - Who cited this? | PubMed ID: 18714163 | Fulltext

Non-fucosylated therapeutic antibodies: the next generation of therapeutic antibodies.

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Mori K, Iida S, Yamane-Ohnuki N, Kanda Y, Kuni-Kamochi R, Nakano R, Imai-Nishiya H, Okazaki A, Shinkawa T, Natsume A, Niwa R, Shitara K, and Satoh M

Cytotechnology 55(2-3):109-14, 2007 Dec - Who cited this? | PubMed ID: 19003000 | Fulltext

A case of suspected vasospastic angina related to S-1 administration.

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Shitara K, Kameda K, Hoshi Y, Munakata M, Muto O, and Sakata Y

Gan to kagaku ryoho. Cancer & chemotherapy 34(10):1705-8, 2007 Oct - Who cited this? | PubMed ID: 17940396 | Fulltext

Oxaliplatin plus 5-fluorouracil/leucovorin (FOLFOX-4) as salvage chemotherapy in patients with pretreated colorectal cancer.

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Shitara K, Munakata M, Muto O, Kasai M, Okada R, Mitobe S, and Sakata Y

Gan to kagaku ryoho. Cancer & chemotherapy 34(7):1079-84, 2007 Jul - Who cited this? | PubMed ID: 17637544 | Fulltext

[A case of unresectable advanced gallbladder cancer treated by systemic chemotherapy combined with hepatic arterial infusion].

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Ishiguro A, Munakata M, Shitara K, Suzuki K, Takahata T, Itoh J, Sakata Y, and Munakata A

Gan to kagaku ryoho. Cancer & chemotherapy 34(7):1127-30, 2007 Jul - Who cited this? | PubMed ID: 17637555 | Fulltext

Hepatic arterial infusion of oxaliplatin for a patient with hepatic metastases from colon cancer undergoing hemodialysis.

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Shitara K, Munakata M, Muto O, Okada R, Mitobe S, Mino M, Ikami I, and Sakata Y

Japanese journal of clinical oncology 37(7):540-3, 2007 Jul - Who cited this? | PubMed ID: 17675650 | Fulltext

Establishment of a GDP-mannose 4,6-dehydratase (GMD) knockout host cell line: a new strategy for generating completely non-fucosylated recombinant therapeutics.

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Kanda Y, Imai-Nishiya H, Kuni-Kamochi R, Mori K, Inoue M, Kitajima-Miyama K, Okazaki A, Iida S, Shitara K, and Satoh M

Journal of biotechnology 130(3):300-10, 2007 Jun 30 - Who cited this? | PubMed ID: 17559959 | Fulltext

[A case of unresectable advanced pancreatic cancer treated by S-1 with concurrent radiotherapy].

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Ishiguro A, Munakata M, Shitara K, Suzuki K, Takahata T, Itoh J, Aoki M, Sakata Y, and Munakata A

Gan to kagaku ryoho. Cancer & chemotherapy 34(6):937-40, 2007 Jun - Who cited this? | PubMed ID: 17565261 | Fulltext

Structural comparison of fucosylated and nonfucosylated Fc fragments of human immunoglobulin G1.

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Matsumiya S, Yamaguchi Y, Saito J, Nagano M, Sasakawa H, Otaki S, Satoh M, Shitara K, and Kato K

Journal of molecular biology 368(3):767-79, 2007 May 4 - Who cited this? | PubMed ID: 17368483 | Fulltext

Enhanced binding affinity for FcgammaRIIIa of fucose-negative antibody is sufficient to induce maximal antibody-dependent cellular cytotoxicity.

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Masuda K, Kubota T, Kaneko E, Iida S, Wakitani M, Kobayashi-Natsume Y, Kubota A, Shitara K, and Nakamura K

Molecular immunology 44(12):3122-31, 2007 May - Who cited this? | PubMed ID: 17379311 | Fulltext

A case of suspected S-1 induced interstitial pneumonia.

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Shitara K, Munakata M, Koizumi W, and Sakata Y

Gan to kagaku ryoho. Cancer & chemotherapy 34(4):619-22, 2007 Apr - Who cited this? | PubMed ID: 17431352 | Fulltext

A nonfucosylated anti-HER2 antibody augments antibody-dependent cellular cytotoxicity in breast cancer patients.

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Suzuki E, Niwa R, Saji S, Muta M, Hirose M, Iida S, Shiotsu Y, Satoh M, Shitara K, Kondo M, and Toi M

Clinical cancer research : an official journal of the American Association for Cancer Research 13(6):1875, 2007 Mar 15 - Who cited this? | PubMed ID: 17363544 | Fulltext

Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex types.

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Kanda Y, Yamada T, Mori K, Okazaki A, Inoue M, Kitajima-Miyama K, Kuni-Kamochi R, Nakano R, Yano K, Kakita S, Shitara K, and Satoh M

Glycobiology 17(1):104, 2007 Jan - Who cited this? | PubMed ID: 17012310 | Fulltext

Double knockdown of alpha1,6-fucosyltransferase (FUT8) and GDP-mannose 4,6-dehydratase (GMD) in antibody-producing cells: a new strategy for generating fully non-fucosylated therapeutic antibodies with enhanced ADCC.

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Imai-Nishiya H, Mori K, Inoue M, Wakitani M, Iida S, Shitara K, and Satoh M

BMC biotechnology 7:84, 2007 - Who cited this? | PubMed ID: 18047682 | Fulltext

Enhanced Fc-dependent cellular cytotoxicity of Fc fusion proteins derived from TNF receptor II and LFA-3 by fucose removal from Asn-linked oligosaccharides.

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Shoji-Hosaka E, Kobayashi Y, Wakitani M, Uchida K, Niwa R, Nakamura K, and Shitara K

Journal of biochemistry 140(6):777-83, 2006 Dec - Who cited this? | PubMed ID: 17038352 | Fulltext

[Combination chemotherapy with hepatic arterial infusion of 5-fluorouracil (5-FU) and systemic irinotecan (CPT-11) in patients with unresectable liver metastases from colorectal cancer].

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Shitara K, Munakata M, Kudo T, Kasai M, Muto O, Okada R, Mitobe S, Ishiguro A, Sakuraba H, Ikami I, and Sakata Y

Gan to kagaku ryoho. Cancer & chemotherapy 33(13):2033-7, 2006 Dec - Who cited this? | PubMed ID: 17197748 | Fulltext

[A case of advanced hepatocellular carcinoma with lung metastases and cirrhosis that responded to combination chemotherapy with interferon-alpha and 5-fluorouracil].

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Shitara K, Munakata M, Kudo T, Muto O, Okada R, Mitobe S, Sakata Y, Kondo M, Ishii E, and Yabu K

Gan to kagaku ryoho. Cancer & chemotherapy 33(13):2083-6, 2006 Dec - Who cited this? | PubMed ID: 17197759 | Fulltext

Non-fucosylated therapeutic antibodies as next-generation therapeutic antibodies.

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Satoh M, Iida S, and Shitara K

Expert opinion on biological therapy 6(11):1161-73, 2006 Nov - Who cited this? | PubMed ID: 17049014 | Fulltext

[A case of duodenal carcinoma with massive peritoneal carcinomatosis complicating a pulmonary embolism].

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Shitara K, Munakata M, Sakata Y, Ishii E, Kondo M, and Wada R

Gan to kagaku ryoho. Cancer & chemotherapy 33(11):1661-4, 2006 Nov - Who cited this? | PubMed ID: 17108737 | Fulltext

[Dislocation of an indwelling catheter from digestive organs in arterial infusion chemotherapy].

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Otsuki S, Fukunari H, Fujimori Y, Shitara K, and Hayashi T

Gan to kagaku ryoho. Cancer & chemotherapy 33(12):1785-7, 2006 Nov - Who cited this? | PubMed ID: 17212107 | Fulltext

[A case of diffuse invasive hepatocellular carcinoma associated with thrombosis of the main trunk of the portal vein in which hepatic transcatheter arterial chemoembolization concomitant to the use of degradable starch microspheres (DSM-TACE) was very effective].

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Shitara K, Fukunari H, Fujimori Y, Sho O, and Hayashi T

Gan to kagaku ryoho. Cancer & chemotherapy 33(12):1807-10, 2006 Nov - Who cited this? | PubMed ID: 17212114 | Fulltext

[A case of advanced gastric cancer with long-term survival treated by chemotherapy and surgical cytoreduction].

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Ishiguro A, Munakata M, Shitara K, Kasai M, and Sakata Y

Gan to kagaku ryoho. Cancer & chemotherapy 33(10):1457-60, 2006 Oct - Who cited this? | PubMed ID: 17033237 | Fulltext

[Colonic perforation in a patient treated with combination chemotherapy for recurrent ovarian clear cell adenocarcinoma].

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Shitara K, Munakata M, Ishiguro A, Kudo T, Okada R, Tomioka R, Mitobe S, Yokoyama S, and Sakata Y

Gan to kagaku ryoho. Cancer & chemotherapy 33(10):1497-1500, 2006 Oct - Who cited this? | PubMed ID: 17033246 | Fulltext

Retrospective analysis of stage IV advanced gastric cancer treated with S-1 or other chemotherapy.

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Shitara K, Ishiguro A, Munakata M, Wada R, and Sakata Y

International journal of clinical oncology / Japan Society of Clinical Oncology 11(5):367-74, 2006 Oct - Who cited this? | PubMed ID: 17058134 | Fulltext

Fucose removal from complex-type oligosaccharide enhances the antibody-dependent cellular cytotoxicity of single-gene-encoded bispecific antibody comprising of two single-chain antibodies linked to the antibody constant region.

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Natsume A, Wakitani M, Yamane-Ohnuki N, Shoji-Hosaka E, Niwa R, Uchida K, Satoh M, and Shitara K

Journal of biochemistry 140(3):359-68, 2006 Sep - Who cited this? | PubMed ID: 16861252 | Fulltext

[A case of advanced esophageal cancer with suspected tracheoesophageal fistula that responded to chemoradiotherapy].

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Shitara K, Munakata M, Ishiguro A, Hoshi Y, Okada R, Tomioka R, Mitobe S, Sakata Y, Ebina A, and Aoki M

Gan to kagaku ryoho. Cancer & chemotherapy 33(8):1137-41, 2006 Aug - Who cited this? | PubMed ID: 16912535 | Fulltext

Comparison of cell lines for stable production of fucose-negative antibodies with enhanced ADCC.

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Kanda Y, Yamane-Ohnuki N, Sakai N, Yamano K, Nakano R, Inoue M, Misaka H, Iida S, Wakitani M, Konno Y, Yano K, Shitara K, Hosoi S, and Satoh M

Biotechnology and bioengineering 94(4):680-8, 2006 Jul 5 - Who cited this? | PubMed ID: 16609957 | Fulltext

[A case of recurrent breast cancer complicated with pericardial effusions and cardiac tamponade].

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Shitara K, Munakata M, Ishiguro A, Okada R, Tomioka R, Mitobe S, and Sakata Y

Gan to kagaku ryoho. Cancer & chemotherapy 33(7):961-4, 2006 Jul - Who cited this? | PubMed ID: 16835487 | Fulltext

[S-1 for gastric cancer-S-1 monotherapy and its progress].

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Shitara K, Sakata Y, Kudou T, and Munakata M

Gan to kagaku ryoho. Cancer & chemotherapy 33 Suppl 1:43-51, 2006 Jun - Who cited this? | PubMed ID: 16897971 | Fulltext

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