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Papers authored by Shi GP

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Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation.

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Sun J, Zhang J, Lindholt JS, Sukhova GK, Liu J, He A, Abrink M, Pejler G, Stevens RL, Thompson RW, Ennis TL, Gurish MF, Libby P, and Shi GP

Circulation 120(11):973-82, 2009 Sep 15 - Who cited this? | PubMed ID: 19720934 | Fulltext

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice.

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Liu J, Divoux A, Sun J, Zhang J, Clément K, Glickman JN, Sukhova GK, Wolters PJ, Du J, Gorgun CZ, Doria A, Libby P, Blumberg RS, Kahn BB, Hotamisligil GS, and Shi GP

Nature medicine 15(8):940-5, 2009 Aug - Who cited this? | PubMed ID: 19633655 | Fulltext

Mechanism of diastolic stiffening of the failing myocardium and its prevention by angiotensin receptor and calcium channel blockers.

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Cheng XW, Okumura K, Kuzuya M, Jin Z, Nagata K, Obata K, Inoue A, Hirashiki A, Takeshita K, Unno K, Harada K, Shi GP, Yokota M, and Murohara T

Journal of cardiovascular pharmacology 54(1):47-56, 2009 Jul - Who cited this? | PubMed ID: 19528815 | Fulltext

The immunomodulatory action of sialostatin L on dendritic cells reveals its potential to interfere with autoimmunity.

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Sá-Nunes A, Bafica A, Antonelli LR, Choi EY, Francischetti IM, Andersen JF, Shi GP, Chavakis T, Ribeiro JM, and Kotsyfakis M

Journal of immunology (Baltimore, Md. : 1950) 182(12):7422-9, 2009 Jun 15 - Who cited this? | PubMed ID: 19494265 | Fulltext

Arterial and aortic valve calcification abolished by elastolytic cathepsin S deficiency in chronic renal disease.

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Aikawa E, Aikawa M, Libby P, Figueiredo JL, Rusanescu G, Iwamoto Y, Fukuda D, Kohler RH, Shi GP, Jaffer FA, and Weissleder R

Circulation 119(13):1785-94, 2009 Apr 7 - Who cited this? | PubMed ID: 19307473 | Fulltext

Complement Regulator CD59 Protects Against Atherosclerosis by Restricting the Formation of Complement Membrane Attack Complex.

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Wu G, Hu W, Shahsafaei A, Song W, Dobarro M, Sukhova GK, Bronson RR, Shi GP, Rother RP, Halperin JA, and Qin X

Circulation research 104(4):550-8, 2009 Feb 27 - Who cited this? | PubMed ID: 19131645 | Fulltext

Usefulness of serum cathepsin L as an independent biomarker in patients with coronary heart disease.

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Liu Y, Li X, Peng D, Tan Z, Liu H, Qing Y, Xue Y, and Shi GP

The American journal of cardiology 103(4):476-81, 2009 Feb 15 - Who cited this? | PubMed ID: 19195505 | Fulltext

Leukocyte cathepsin S is a potent regulator of both cell and matrix turnover in advanced atherosclerosis.

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de Nooijer R, Bot I, von der Thüsen JH, Leeuwenburgh MA, Overkleeft HS, Kraaijeveld AO, Dorland R, van Santbrink PJ, van Heiningen SH, Westra MM, Kovanen PT, Jukema JW, van der Wall EE, van Berkel TJ, Shi GP, and Biessen EA

Arteriosclerosis, thrombosis, and vascular biology 29(2):188-94, 2009 Feb - Who cited this? | PubMed ID: 19095996 | Fulltext

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.

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Ewald SE, Lee BL, Lau L, Wickliffe KE, Shi GP, Chapman HA, and Barton GM

Nature, 2008 Sep 28 - Who cited this? | PubMed ID: 18820679 | Fulltext

Deficiency and Inhibition of Cathepsin K Reduce Body Weight Gain and Increase Glucose Metabolism in Mice.

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Yang M, Sun J, Zhang T, Liu J, Zhang J, Shi MA, Darakhshan F, Guerre-Millo M, Clement K, Gelb BD, Dolgnov G, and Shi GP

Arteriosclerosis, thrombosis, and vascular biology, 2008 Sep 25 - Who cited this? | PubMed ID: 18818416 | Fulltext

[Cathepsin S in pathogenesis of neurological diseases.].

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Wang DM, Liu JR, Hu HY, and Shi GP

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 37(4):422-6, 2008 Jul - Who cited this? | PubMed ID: 18705018 | Fulltext

Superoxide-Dependent Cathepsin Activation Is Associated with Hypertensive Myocardial Remodeling and Represents a Target for Angiotensin II Type 1 Receptor Blocker Treatment.

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Cheng XW, Murohara T, Kuzuya M, Izawa H, Sasaki T, Obata K, Nagata K, Nishizawa T, Kobayashi M, Yamada T, Kim W, Sato K, Shi GP, Okumura K, and Yokota M

The American journal of pathology, 2008 Jun 26 - Who cited this? | PubMed ID: 18583318 | Fulltext

Matrix metalloproteinase-14 deficiency in bone marrow-derived cells promotes collagen accumulation in mouse atherosclerotic plaques.

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Schneider F, Sukhova GK, Aikawa M, Canner J, Gerdes N, Tang SM, Shi GP, Apte SS, and Libby P

Circulation 117(7):931-9, 2008 Feb 19 - Who cited this? | PubMed ID: 18250269 | Fulltext

Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice.

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Sun J, Sukhova GK, Yang M, Wolters PJ, MacFarlane LA, Libby P, Sun C, Zhang Y, Liu J, Ennis TL, Knispel R, Xiong W, Thompson RW, Baxter BT, and Shi GP

The Journal of clinical investigation 117(11):3359, 2007 Nov - Who cited this? | PubMed ID: 17932568 | Fulltext

Role of cathepsin C in elastase-induced mouse abdominal aortic aneurysms.

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Shi GP

Future cardiology 3(6):591-3, 2007 Nov - Who cited this? | PubMed ID: 19804279 | Fulltext

Cathepsin S deficiency confers protection from neonatal hyperoxia-induced lung injury.

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Hirakawa H, Pierce RA, Bingol-Karakoc G, Karaaslan C, Weng M, Shi GP, Saad A, Weber E, Mariani TJ, Starcher B, Shapiro SD, and Cataltepe S

American journal of respiratory and critical care medicine 176(8):778-85, 2007 Oct 15 - Who cited this? | PubMed ID: 17673697 | Fulltext

Cathepsin L activity controls adipogenesis and glucose tolerance.

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Yang M, Zhang Y, Pan J, Sun J, Liu J, Libby P, Sukhova GK, Doria A, Katunuma N, Peroni OD, Guerre-Millo M, Kahn BB, Clement K, and Shi GP

Nature cell biology 9(8):970-7, 2007 Aug - Who cited this? | PubMed ID: 17643114 | Fulltext

Mast cells promote atherosclerosis by releasing proinflammatory cytokines.

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Sun J, Sukhova GK, Wolters PJ, Yang M, Kitamoto S, Libby P, MacFarlane LA, Mallen-St Clair J, and Shi GP

Nature medicine 13(6):719-24, 2007 Jun - Who cited this? | PubMed ID: 17546038 | Fulltext

Mast cells as mediators and modulators of atherogenesis.

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Libby P and Shi GP

Circulation 115(19):2471-3, 2007 May 15 - Who cited this? | PubMed ID: 17502588 | Fulltext

Optical visualization of cathepsin K activity in atherosclerosis with a novel, protease-activatable fluorescence sensor.

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Jaffer FA, Kim DE, Quinti L, Tung CH, Aikawa E, Pande AN, Kohler RH, Shi GP, Libby P, and Weissleder R

Circulation 115(17):2292, 2007 May 1 - Who cited this? | PubMed ID: 17420353 | Fulltext

Cathepsin L deficiency reduces diet-induced atherosclerosis in low-density lipoprotein receptor-knockout mice.

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Kitamoto S, Sukhova GK, Sun J, Yang M, Libby P, Love V, Duramad P, Sun C, Zhang Y, Yang X, Peters C, and Shi GP

Circulation 115(15):2065, 2007 Apr 17 - Who cited this? | PubMed ID: 17404153 | Fulltext

Expression of cathepsin K is regulated by shear stress in cultured endothelial cells and is increased in endothelium in human atherosclerosis.

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Platt MO, Ankeny RF, Shi GP, Weiss D, Vega JD, Taylor WR, and Jo H

American journal of physiology. Heart and circulatory physiology 292(3):H1479-86, 2007 Mar - Who cited this? | PubMed ID: 17098827 | Fulltext

Cathepsin L function in insect moulting: molecular cloning and functional analysis in cotton bollworm, Helicoverpa armigera.

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Liu J, Shi GP, Zhang WQ, Zhang GR, and Xu WH

Insect molecular biology 15(6):823-34, 2006 Dec - Who cited this? | PubMed ID: 17201774 | Fulltext

Cutting edge: Deficiency of macrophage migration inhibitory factor impairs murine airway allergic responses.

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Wang B, Huang X, Wolters PJ, Sun J, Kitamoto S, Yang M, Riese R, Leng L, Chapman HA, Finn PW, David JR, Bucala R, and Shi GP

Journal of immunology (Baltimore, Md. : 1950) 177(9):5779, 2006 Nov 1 - Who cited this? | PubMed ID: 17056501 | Fulltext

Elastolytic cathepsin induction/activation system exists in myocardium and is upregulated in hypertensive heart failure.

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Cheng XW, Obata K, Kuzuya M, Izawa H, Nakamura K, Asai E, Nagasaka T, Saka M, Kimata T, Noda A, Nagata K, Jin H, Shi GP, Iguchi A, Murohara T, and Yokota M

Hypertension 48(5):979-87, 2006 Nov - Who cited this? | PubMed ID: 16982960 | Fulltext

Do cathepsins play a role in abdominal aortic aneurysm pathogenesis?.

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Sukhova GK and Shi GP

Annals of the New York Academy of Sciences 1085:161-9, 2006 Nov - Who cited this? | PubMed ID: 17182932 | Fulltext

Cathepsins L and S are not required for activation of dipeptidyl peptidase I (cathepsin C) in mice.

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Mallen-St Clair J, Shi GP, Sutherland RE, Chapman HA, Caughey GH, and Wolters PJ

Biological chemistry 387(8):1143, 2006 Aug - Who cited this? | PubMed ID: 16895486 | Fulltext

Atherosclerosis progression and monocyte emigration from plaque.

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Packard RR and Shi GP

Future cardiology 2(4):415-8, 2006 Jul - Who cited this? | PubMed ID: 19804177 | Fulltext

Increased serum cathepsin S in patients with atherosclerosis and diabetes.

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Liu J, Ma L, Yang J, Ren A, Sun Z, Yan G, Sun J, Fu H, Xu W, Hu C, and Shi GP

Atherosclerosis 186(2):411-9, 2006 Jun - Who cited this? | PubMed ID: 16140306 | Fulltext

Chronic inflammation, immune response, and infection in abdominal aortic aneurysms.

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Lindholt JS and Shi GP

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 31(5):453-63, 2006 May - Who cited this? | PubMed ID: 16414293 | Fulltext

Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors.

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Wang B, Sun J, Kitamoto S, Yang M, Grubb A, Chapman HA, Kalluri R, and Shi GP

The Journal of biological chemistry 281(9):6020-9, 2006 Mar 3 - Who cited this? | PubMed ID: 16365041 | Fulltext

Comprehensive transcriptome of proteases and protease inhibitors in vascular cells.

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Shi GP and Dolganov GM

Stroke; a journal of cerebral circulation 37(2):537, 2006 Feb - Who cited this? | PubMed ID: 16373647 | Fulltext

Cathepsin L expression and regulation in human abdominal aortic aneurysm, atherosclerosis, and vascular cells.

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Liu J, Sukhova GK, Yang JT, Sun J, Ma L, Ren A, Xu WH, Fu H, Dolganov GM, Hu C, Libby P, and Shi GP

Atherosclerosis 184(2):302-11, 2006 Feb - Who cited this? | PubMed ID: 15982660 | Fulltext

Localization of cysteine protease, cathepsin S, to the surface of vascular smooth muscle cells by association with integrin alphanubeta3.

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Cheng XW, Kuzuya M, Nakamura K, Di Q, Liu Z, Sasaki T, Kanda S, Jin H, Shi GP, Murohara T, Yokota M, and Iguchi A

The American journal of pathology 168(2):685-94, 2006 Feb - Who cited this? | PubMed ID: 16436681 | Fulltext

Cathepsins: novel drug targets for cardiovascular diseases?.

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Shi GP

Future cardiology 1(5):563-5, 2005 Sep - Who cited this? | PubMed ID: 19804093 | Fulltext

Cystatin C deficiency increases elastic lamina degradation and aortic dilatation in apolipoprotein E-null mice.

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Sukhova GK, Wang B, Libby P, Pan JH, Zhang Y, Grubb A, Fang K, Chapman HA, and Shi GP

Circulation research 96(3):368-75, 2005 Feb 18 - Who cited this? | PubMed ID: 15653570 | Fulltext

Assignment of murine placental cathepsin R to mouse chromosome bands 13B2-B3 by fluorescence in situ hybridization.

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Zimonjic DB, Liu J, Xu WH, Zhou X, Popescu NC, and Shi GP

Cytogenetic and genome research 111(1):96, 2005 - Who cited this? | PubMed ID: 16097084 | Fulltext

Lysosomal cysteine proteases in atherosclerosis.

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Liu J, Sukhova GK, Sun JS, Xu WH, Libby P, and Shi GP

Arteriosclerosis, thrombosis, and vascular biology 24(8):1359-66, 2004 Aug - Who cited this? | PubMed ID: 15178558 | Fulltext

Macrophage migration inhibitory factor deficiency impairs atherosclerosis in low-density lipoprotein receptor-deficient mice.

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Pan JH, Sukhova GK, Yang JT, Wang B, Xie T, Fu H, Zhang Y, Satoskar AR, David JR, Metz CN, Bucala R, Fang K, Simon DI, Chapman HA, Libby P, and Shi GP

Circulation 109(25):3149-53, 2004 Jun 29 - Who cited this? | PubMed ID: 15197138 | Fulltext

Increased expression of elastolytic cysteine proteases, cathepsins S and K, in the neointima of balloon-injured rat carotid arteries.

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Cheng XW, Kuzuya M, Sasaki T, Arakawa K, Kanda S, Sumi D, Koike T, Maeda K, Tamaya-Mori N, Shi GP, Saito N, and Iguchi A

The American journal of pathology 164(1):243-51, 2004 Jan - Who cited this? | PubMed ID: 14695337 | Fulltext

Relationships between activators and inhibitors of plasminogen, and the progression of small abdominal aortic aneurysms.

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Lindholt JS, Jørgensen B, Shi GP, and Henneberg EW

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 25(6):546-51, 2003 Jun - Who cited this? | PubMed ID: 12787697 | Fulltext

Deficiency of the cysteine protease cathepsin S impairs microvessel growth.

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Shi GP, Sukhova GK, Kuzuya M, Ye Q, Du J, Zhang Y, Pan JH, Lu ML, Cheng XW, Iguchi A, Perrey S, Lee AM, Chapman HA, and Libby P

Circulation research 92(5):493-500, 2003 Mar 21 - Who cited this? | PubMed ID: 12600886 | Fulltext

Macrophage migration inhibitory factor is associated with aneurysmal expansion.

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Pan JH, Lindholt JS, Sukhova GK, Baugh JA, Henneberg EW, Bucala R, Donnelly SC, Libby P, Metz C, and Shi GP

Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 37(3):628, 2003 Mar - Who cited this? | PubMed ID: 12618703 | Fulltext

Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice.

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Sukhova GK, Zhang Y, Pan JH, Wada Y, Yamamoto T, Naito M, Kodama T, Tsimikas S, Witztum JL, Lu ML, Sakara Y, Chin MT, Libby P, and Shi GP

The Journal of clinical investigation 111(6):897-906, 2003 Mar - Who cited this? | PubMed ID: 12639996 | Fulltext

[Effects of hydrogen peroxide on intracellular free Ca2+ content in rat liver oval cells].

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Shi GP, Du HZ, Liu ZW, Liu X, and Wu YD

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 24(3):281-4, 2002 Jun - Who cited this? | PubMed ID: 12905635 | Fulltext

Regulation of CD1 function and NK1.1(+) T cell selection and maturation by cathepsin S.

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Riese RJ, Shi GP, Villadangos J, Stetson D, Driessen C, Lennon-Dumenil AM, Chu CL, Naumov Y, Behar SM, Ploegh H, Locksley R, and Chapman HA

Immunity 15(6):909-19, 2001 Dec - Who cited this? | PubMed ID: 11754813 | Fulltext

[Role of hydrogen peroxide in promoting proliferation and transformation of rat liver oval cell line WB-F344].

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Shi GP, Li Y, Wang QY, and Wu YD

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 23(4):346-50, 2001 Aug - Who cited this? | PubMed ID: 12940074 | Fulltext

The transcription factor early growth-response factor 1 modulates tumor necrosis factor-alpha, immunoglobulin E, and airway responsiveness in mice.

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Silverman ES, De Sanctis GT, Boyce J, Maclean JA, Jiao A, Green FH, Grasemann H, Faunce D, Fitzmaurice G, Shi GP, Stein-Streilein J, Milbrandt J, Collins T, and Drazen JM

American journal of respiratory and critical care medicine 163(3 Pt 1):778-85, 2001 Mar - Who cited this? | PubMed ID: 11254538 | Fulltext

Expression of cathepsins B and S in the progression of prostate carcinoma.

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Fernández PL, Farré X, Nadal A, Fernández E, Peiró N, Sloane BF, Shi GP, Chapman HA, Campo E, and Cardesa A

International journal of cancer. Journal international du cancer 95(1):51-5, 2001 Jan 20 - Who cited this? | PubMed ID: 11241311 | Fulltext

Pathologic gene expression in Gaucher disease: up-regulation of cysteine proteinases including osteoclastic cathepsin K.

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Moran MT, Schofield JP, Hayman AR, Shi GP, Young E, and Cox TM

Blood 96(5):1969-78, 2000 Sep 1 - Who cited this? | PubMed ID: 10961902 | Fulltext

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