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Papers authored by Shepherd FA

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Resident preparedness in discussing prognosis in patients with advanced lung cancer.

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Wheatley-Price P, Massey C, Panzarella T, Shepherd FA, and Mikhael J

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 18(4):491-7, 2010 Apr - Who cited this? | PubMed ID: 19629536 | Fulltext

Economic analysis: randomized placebo-controlled clinical trial of erlotinib in advanced non-small cell lung cancer.

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Bradbury PA, Tu D, Seymour L, Isogai PK, Zhu L, Ng R, Mittmann N, Tsao MS, Evans WK, Shepherd FA, Leighl NB, and NCIC Clinical Trials Group Working Group on Economic Analysis

Journal of the National Cancer Institute 102(5):298-306, 2010 Mar 3 - Who cited this? | PubMed ID: 20160168 | Fulltext

Treatment of small-cell lung cancer in elderly patients.

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Pallis AG, Shepherd FA, Lacombe D, and Gridelli C

Cancer 116(5):1192-200, 2010 Mar 1 - Who cited this? | PubMed ID: 20082450 | Fulltext

Epidermal growth factor receptor biomarkers in non-small-cell lung cancer: a riddle, wrapped in a mystery, inside an enigma.

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Shepherd FA and Tsao MS

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 28(6):903-5, 2010 Feb 20 - Who cited this? | PubMed ID: 20100955 | Fulltext

Molecular Predictors of Outcome With Gefitinib and Docetaxel in Previously Treated Non-Small-Cell Lung Cancer: Data From the Randomized Phase III INTEREST Trial.

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Douillard JY, Shepherd FA, Hirsh V, Mok T, Socinski MA, Gervais R, Liao ML, Bischoff H, Reck M, Sellers MV, Watkins CL, Speake G, Armour AA, and Kim ES

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 28(5):744-52, 2010 Feb 10 - Who cited this? | PubMed ID: 20038723 | Fulltext

Surgery for limited stage small cell lung cancer: time to fish or cut bait.

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Shepherd FA

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 5(2):147-9, 2010 Feb - Who cited this? | PubMed ID: 20101141 | Fulltext

Adjuvant cisplatin and vinorelbine for completely resected non-small cell lung cancer: subgroup analysis of the Lung Adjuvant Cisplatin Evaluation.

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Douillard JY, Tribodet H, Aubert D, Shepherd FA, Rosell R, Ding K, Veillard AS, Seymour L, Le Chevalier T, Spiro S, Stephens R, Pignon JP, and LACE Collaborative Group

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 5(2):220-8, 2010 Feb - Who cited this? | PubMed ID: 20027124 | Fulltext

The strength of female sex as a prognostic factor in small-cell lung cancer: a pooled analysis of chemotherapy trials from the Manchester Lung Group and Medical Research Council Clinical Trials Unit.

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Wheatley-Price P, Ma C, Ashcroft LF, Nankivell M, Stephens RJ, White SC, Lorigan P, Thatcher N, Blackhall FH, and Shepherd FA

Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 21(2):232-7, 2010 Feb - Who cited this? | PubMed ID: 19675093 | Fulltext

Lung cancer screening using low-dose computed tomography in at-risk individuals: the Toronto experience.

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Menezes RJ, Roberts HC, Paul NS, McGregor M, Chung TB, Patsios D, Weisbrod G, Herman S, Pereira A, McGregor A, Dong Z, Sitartchouk I, Boerner S, Tsao MS, Keshavjee S, and Shepherd FA

Lung cancer (Amsterdam, Netherlands) 67(2):177-83, 2010 Feb - Who cited this? | PubMed ID: 19427055 | Fulltext

Randomized, Double-Blind Trial of Carboplatin and Paclitaxel With Either Daily Oral Cediranib or Placebo in Advanced Non-Small-Cell Lung Cancer: NCIC Clinical Trials Group BR24 Study.

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Goss GD, Arnold A, Shepherd FA, Dediu M, Ciuleanu TE, Fenton D, Zukin M, Walde D, Laberge F, Vincent MD, Ellis PM, Laurie SA, Ding K, Frymire E, Gauthier I, Leighl NB,

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Journal of clinical oncology : official journal of the American Society of Clinical Oncology 28(1):49-55, 2010 Jan 1 - Who cited this? | PubMed ID: 19917841 | Fulltext

Randomized Phase III Trial of Vinorelbine Plus Cisplatin Compared With Observation in Completely Resected Stage IB and II Non-Small-Cell Lung Cancer: Updated Survival Analysis of JBR-10.

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Butts CA, Ding K, Seymour L, Twumasi-Ankrah P, Graham B, Gandara D, Johnson DH, Kesler KA, Green M, Vincent M, Cormier Y, Goss G, Findlay B, Johnston M, Tsao MS, and Shepherd FA

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 28(1):29-34, 2010 Jan 1 - Who cited this? | PubMed ID: 19933915 | Fulltext

Phase II Study of Preoperative Gefitinib in Clinical Stage I Non-Small-Cell Lung Cancer.

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Lara-Guerra H, Waddell TK, Salvarrey MA, Joshua AM, Chung CT, Paul N, Boerner S, Sakurada A, Ludkovski O, Ma C, Squire J, Liu G, Shepherd FA, Tsao MS, and Leighl NB

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27(36):6229-36, 2009 Dec 20 - Who cited this? | PubMed ID: 19884551 | Fulltext

Venous thromboembolism and nonsmall cell lung cancer: a pooled analysis of National Cancer Institute of Canada Clinical Trials Group trials.

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Hicks LK, Cheung MC, Ding K, Hasan B, Seymour L, Le Maître A, Leighl NB, and Shepherd FA

Cancer 115(23):5516-25, 2009 Dec 1 - Who cited this? | PubMed ID: 19711465 | Fulltext

Venous thromboembolism in patients receiving multimodality therapy for thoracic malignancies.

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Patel A, Anraku M, Darling GE, Shepherd FA, Pierre AF, Waddell TK, Keshavjee S, and de Perrot M

The Journal of thoracic and cardiovascular surgery 138(4):843-8, 2009 Oct - Who cited this? | PubMed ID: 19660355 | Fulltext

Efficacy of everolimus (RAD001) in patients with advanced NSCLC previously treated with chemotherapy alone or with chemotherapy and EGFR inhibitors.

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Soria JC, Shepherd FA, Douillard JY, Wolf J, Giaccone G, Crino L, Cappuzzo F, Sharma S, Gross SH, Dimitrijevic S, Di Scala L, Gardner H, Nogova L, and Papadimitrakopoulou V

Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 20(10):1674-81, 2009 Oct - Who cited this? | PubMed ID: 19549709 | Fulltext

Molecular predictive and prognostic markers in non-small-cell lung cancer.

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Coate LE, John T, Tsao MS, and Shepherd FA

The lancet oncology 10(10):1001-10, 2009 Oct - Who cited this? | PubMed ID: 19796752 | Fulltext

Quality-adjusted time without symptoms or toxicity analysis of adjuvant chemotherapy in non-small-cell lung cancer: an analysis of the National Cancer Institute of Canada Clinical Trials Group JBR.10 trial.

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Jang RW, Le Maître A, Ding K, Winton T, Bezjak A, Seymour L, Shepherd FA, and Leighl NB

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27(26):4268-73, 2009 Sep 10 - Who cited this? | PubMed ID: 19667274 | Fulltext

The IASLC Lung Cancer Staging Project: proposals regarding the relevance of TNM in the pathologic staging of small cell lung cancer in the forthcoming (seventh) edition of the TNM classification for lung cancer.

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Vallières E, Shepherd FA, Crowley J, Van Houtte P, Postmus PE, Carney D, Chansky K, Shaikh Z, Goldstraw P, and International Association for the Study of Lung Cancer International Staging Committee and Participating Institutions

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 4(9):1049-59, 2009 Sep - Who cited this? | PubMed ID: 19652623 | Fulltext

A phase I/II study of GTI-2040 plus docetaxel as second-line treatment in advanced non-small cell lung cancer: a study of the PMH phase II consortium.

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Leighl NB, Laurie SA, Chen XE, Ellis P, Shepherd FA, Knox JJ, Goss G, Burkes RL, Pond GR, Dick C, Yen Y, Zwiebel JA, and Moore MJ

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 4(9):1163-9, 2009 Sep - Who cited this? | PubMed ID: 19704337 | Fulltext

Understanding prognostic gene expression signatures in lung cancer.

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Zhu CQ, Pintilie M, John T, Strumpf D, Shepherd FA, Der SD, Jurisica I, and Tsao MS

Clinical lung cancer 10(5):331-40, 2009 Sep - Who cited this? | PubMed ID: 19808191 | Fulltext

A randomized phase 2 study of erlotinib alone and in combination with bortezomib in previously treated advanced non-small cell lung cancer.

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Lynch TJ, Fenton D, Hirsh V, Bodkin D, Middleman EL, Chiappori A, Halmos B, Favis R, Liu H, Trepicchio WL, Eton O, and Shepherd FA

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 4(8):1002-9, 2009 Aug - Who cited this? | PubMed ID: 19633475 | Fulltext

Radiotherapy plus chemotherapy with or without surgical resection for stage III non-small-cell lung cancer: a phase III randomised controlled trial.

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Albain KS, Swann RS, Rusch VW, Turrisi AT, Shepherd FA, Smith C, Chen Y, Livingston RB, Feins RH, Gandara DR, Fry WA, Darling G, Johnson DH, Green MR, Miller RC, Ley J,

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Lancet 374(9687):379-86, 2009 Aug 1 - Who cited this? | PubMed ID: 19632716 | Fulltext

Cisplatin pharmacogenetics, DNA repair polymorphisms, and esophageal cancer outcomes.

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Bradbury PA, Kulke MH, Heist RS, Zhou W, Ma C, Xu W, Marshall AL, Zhai R, Hooshmand SM, Asomaning K, Su L, Shepherd FA, Lynch TJ, Wain JC, Christiani DC, and Liu G

Pharmacogenetics and genomics 19(8):613-25, 2009 Aug - Who cited this? | PubMed ID: 19620936 | Fulltext

The IASLC Lung Cancer Staging Project: data elements for the prospective project.

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Giroux DJ, Rami-Porta R, Chansky K, Crowley JJ, Groome PA, Postmus PE, Rusch V, Sculier JP, Shepherd FA, Sobin L, Goldstraw P, and International Association for the Study of Lung Cancer International Staging Committee

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 4(6):679-83, 2009 Jun - Who cited this? | PubMed ID: 19461401 | Fulltext

Anticoagulation and bleeding: a pooled analysis of lung cancer trials of the NCIC Clinical Trials Group.

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Le Maître A, Ding K, Shepherd FA, Leighl N, Arnold A, Seymour L, and NCIC Clinical Trials Group

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 4(5):586-94, 2009 May - Who cited this? | PubMed ID: 19357539 | Fulltext

A phase I and pharmacokinetic study of daily oral cediranib, an inhibitor of vascular endothelial growth factor tyrosine kinases, in combination with cisplatin and gemcitabine in patients with advanced non-small cell lung cancer: A study of the National Cancer Institute of Canada Clinical Trials Group.

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Goss G, Shepherd FA, Laurie S, Gauthier I, Leighl N, Chen E, Feld R, Powers J, and Seymour L

European journal of cancer (Oxford, England : 1990) 45(5):782-8, 2009 Mar - Who cited this? | PubMed ID: 19091548 | Fulltext

The Differential Efficacy of Pemetrexed According to NSCLC Histology: A Review of Two Phase III Studies.

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Scagliotti G, Hanna N, Fossella F, Sugarman K, Blatter J, Peterson P, Simms L, and Shepherd FA

The oncologist 14(3):253-63, 2009 Mar - Who cited this? | PubMed ID: 19221167 | Fulltext

Prognostic gene signatures for non-small-cell lung cancer.

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Boutros PC, Lau SK, Pintilie M, Liu N, Shepherd FA, Der SD, Tsao MS, Penn LZ, and Jurisica I

Proceedings of the National Academy of Sciences of the United States of America 106(8):2824-8, 2009 Feb 24 - Who cited this? | PubMed ID: 19196983 | Fulltext

Predictors of referral for specialized psychosocial oncology care in patients with metastatic cancer: the contributions of age, distress, and marital status.

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Ellis J, Lin J, Walsh A, Lo C, Shepherd FA, Moore M, Li M, Gagliese L, Zimmermann C, and Rodin G

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27(5):699-705, 2009 Feb 10 - Who cited this? | PubMed ID: 19114706 | Fulltext

Prevention and management of bone metastases in lung cancer: a review.

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Al Husaini H, Wheatley-Price P, Clemons M, and Shepherd FA

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 4(2):251-9, 2009 Feb - Who cited this? | PubMed ID: 19179905 | Fulltext

Induction chemoradiotherapy facilitates radical resection of T4 non-small cell lung cancer invading the spine.

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Anraku M, Waddell TK, de Perrot M, Lewis SJ, Pierre AF, Darling GE, Johnston MR, Zener RE, Rampersaud YR, Shepherd FA, Leighl N, Bezjak A, Sun AY, Hwang DM, Tsao MS, and Keshavjee S

The Journal of thoracic and cardiovascular surgery 137(2):441-447.e1, 2009 Feb - Who cited this? | PubMed ID: 19185167 | Fulltext

Tumor cavitation: impact on objective response evaluation in trials of angiogenesis inhibitors in non-small-cell lung cancer.

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Crabb SJ, Patsios D, Sauerbrei E, Ellis PM, Arnold A, Goss G, Leighl NB, Shepherd FA, Powers J, Seymour L, and Laurie SA

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27(3):404-10, 2009 Jan 20 - Who cited this? | PubMed ID: 19047292 | Fulltext

The role of the epidermal growth factor receptor tyrosine kinase inhibitors as therapy for advanced, metastatic, and recurrent non-small-cell lung cancer: a Canadian national consensus statement.

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Ellis PM, Morzycki W, Melosky B, Butts C, Hirsh V, Krasnoshtein F, Murray N, Shepherd FA, Soulieres D, Tsao MS, and Goss G

Current oncology (Toronto, Ont.) 16(1):27-48, 2009 Jan - Who cited this? | PubMed ID: 19229369 | Fulltext

Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial.

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Kim ES, Hirsh V, Mok T, Socinski MA, Gervais R, Wu YL, Li LY, Watkins CL, Sellers MV, Lowe ES, Sun Y, Liao ML, Osterlind K, Reck M, Armour AA, Shepherd FA,

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Lancet 372(9652):1809-18, 2008 Nov 22 - Who cited this? | PubMed ID: 19027483 | Fulltext

Targeting angiogenesis in the treatment of lung cancer.

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Wheatley-Price P and Shepherd FA

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 3(10):1173-84, 2008 Oct - Who cited this? | PubMed ID: 18827616 | Fulltext

Quality-of-Life Outcomes for Adjuvant Chemotherapy in Early-Stage Non-Small-Cell Lung Cancer: Results From a Randomized Trial, JBR.10.

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Bezjak A, Lee CW, Ding K, Brundage M, Winton T, Graham B, Whitehead M, Johnson DH, Livingston RB, Seymour L, and Shepherd FA

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008 Sep 22 - Who cited this? | PubMed ID: 18809617 | Fulltext

Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study.

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, Shedden K, Taylor JM, Enkemann SA, Tsao MS, Yeatman TJ, Gerald WL, Eschrich S, Jurisica I, Giordano TJ, Misek DE, Chang AC, Zhu CQ, Strumpf D, Hanash S, Shepherd FA,

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Nature medicine 14(8):822, 2008 Aug - Who cited this? | PubMed ID: 18641660 | Fulltext

Lung Adjuvant Cisplatin Evaluation: A Pooled Analysis by the LACE Collaborative Group.

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Pignon JP, Tribodet H, Scagliotti GV, Douillard JY, Shepherd FA, Stephens RJ, Dunant A, Torri V, Rosell R, Seymour L, Spiro SG, Rolland E, Fossati R, Aubert D, Ding K, Waller D,

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Journal of clinical oncology : official journal of the American Society of Clinical Oncology 26(21):3552-9, 2008 Jul 20 - Who cited this? | PubMed ID: 18506026 | Fulltext

Pooled analysis of the effect of age on adjuvant Cisplatin-based chemotherapy for completely resected non-small-cell lung cancer.

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Früh M, Rolland E, Pignon JP, Seymour L, Ding K, Tribodet H, Winton T, Le Chevalier T, Scagliotti GV, Douillard JY, Spiro S, and Shepherd FA

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 26(21):3573-81, 2008 Jul 20 - Who cited this? | PubMed ID: 18640938 | Fulltext

Role of KRAS and EGFR As Biomarkers of Response to Erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21.

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Zhu CQ, da Cunha Santos G, Ding K, Sakurada A, Cutz JC, Liu N, Zhang T, Marrano P, Whitehead M, Squire JA, Kamel-Reid S, Seymour L, Shepherd FA, and Tsao MS

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008 Jul 14 - Who cited this? | PubMed ID: 18626007 | Fulltext

Validation of treatment induced specific adverse effect as a predictor of treatment benefit: a case study of NCIC CTG BR21.

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Ding K, Pater J, Whitehead M, Seymour L, and Shepherd FA

Contemporary clinical trials 29(4):527-36, 2008 Jul - Who cited this? | PubMed ID: 18280222 | Fulltext

Enhancing treatment decision-making: pilot study of a treatment decision aid in stage IV non-small cell lung cancer.

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Leighl NB, Shepherd FA, Zawisza D, Burkes RL, Feld R, Waldron J, Sun A, Payne D, Bezjak A, and Tattersall MH

British journal of cancer 98(11):1769-73, 2008 Jun 3 - Who cited this? | PubMed ID: 18506180 | Fulltext

Immunotherapy for lung cancer.

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Bradbury PA and Shepherd FA

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 3(6 Suppl 2), 2008 Jun - Who cited this? | PubMed ID: 18520304 | Fulltext

A clinical prognostic index for patients treated with erlotinib in National Cancer Institute of Canada Clinical Trials Group study BR.21.

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Florescu M, Hasan B, Seymour L, Ding K, Shepherd FA, and National Cancer Institute of Canada Clinical Trials Group

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 3(6):590-8, 2008 Jun - Who cited this? | PubMed ID: 18520796 | Fulltext

Molecular selection of patients for first-line treatment of advanced non-small-cell lung cancer with epidermal growth factor inhibitors: not quite ready for prime time.

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Shepherd FA

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 26(15):2426-7, 2008 May 20 - Who cited this? | PubMed ID: 18458043 | Fulltext

Erlotinib for advanced non-small-cell lung cancer in the elderly: an analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR.21.

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Wheatley-Price P, Ding K, Seymour L, Clark GM, and Shepherd FA

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 26(14):2350-7, 2008 May 10 - Who cited this? | PubMed ID: 18467727 | Fulltext

Tissue heterogeneity of EGFR mutation in lung adenocarcinoma.

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Sakurada A, Lara-Guerra H, Liu N, Shepherd FA, and Tsao MS

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 3(5):527, 2008 May - Who cited this? | PubMed ID: 18449007 | Fulltext

Phase I and pharmacokinetic study of daily oral AZD2171, an inhibitor of vascular endothelial growth factor tyrosine kinases, in combination with carboplatin and paclitaxel in patients with advanced non-small-cell lung cancer: the National Cancer Institute of Canada clinical trials group.

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Laurie SA, Gauthier I, Arnold A, Shepherd FA, Ellis PM, Chen E, Goss G, Powers J, Walsh W, Tu D, Robertson J, Puchalski TA, and Seymour L

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 26(11):1871-8, 2008 Apr 10 - Who cited this? | PubMed ID: 18398152 | Fulltext

Second-line treatment of advanced non-small cell lung cancer.

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Gridelli C, Ardizzoni A, Ciardiello F, Hanna N, Heymach JV, Perrone F, Rosell R, Shepherd FA, Thatcher N, Vansteenkiste J, De Petris L, Di Maio M, and De Marinis F

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 3(4):430-40, 2008 Apr - Who cited this? | PubMed ID: 18379366 | Fulltext

Epidermal growth factor receptor inhibitors in the treatment of lung cancer: reality and hopes.

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Wheatley-Price P and Shepherd FA

Current opinion in oncology 20(2):162-75, 2008 Mar - Who cited this? | PubMed ID: 18300766 | Fulltext

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