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Papers authored by Semenkovich CF

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Identification of a Physiologically Relevant Endogenous Ligand for PPARalpha in Liver.

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Chakravarthy MV, Lodhi IJ, Yin L, Malapaka RR, Xu HE, Turk J, and Semenkovich CF

Cell 138(3):476-88, 2009 Aug 7 - Who cited this? | PubMed ID: 19646743 | Fulltext

Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation.

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Chakravarthy MV, Zhu Y, Yin L, Coleman T, Pappan KL, Marshall CA, McDaniel ML, and Semenkovich CF

Journal of lipid research 50(4):630-40, 2009 Apr - Who cited this? | PubMed ID: 19029118 | Fulltext

Getting away from glucose: stop sugarcoating diabetes.

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Razani B and Semenkovich CF

Nature medicine 15(4):372-3, 2009 Apr - Who cited this? | PubMed ID: 19350008 | Fulltext

Why we should put clothes on mice.

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Lodhi IJ and Semenkovich CF

Cell metabolism 9(2):111-2, 2009 Feb - Who cited this? | PubMed ID: 19187768 | Fulltext

Insulin resistance and atherosclerosis.

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Razani B, Chakravarthy MV, and Semenkovich CF

Endocrinology and metabolism clinics of North America 37(3):603-21, 2008 Sep - Who cited this? | PubMed ID: 18775354 | Fulltext

Requirement for p38 mitogen-activated protein kinase activity in neointima formation after vascular injury.

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Proctor BM, Jin X, Lupu TS, Muglia LJ, Semenkovich CF, and Muslin AJ

Circulation 118(6):658, 2008 Aug 5 - Who cited this? | PubMed ID: 18645058 | Fulltext

Decreased Fetal Size is Associated with Beta Cell Hyperfunction in Early Life and Failure with Age.

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Chakravarthy MV, Zhu Y, Wice MB, Coleman T, Pappan KL, Marshall CA, McDaniel ML, and Semenkovich CF

Diabetes, 2008 Jun 30 - Who cited this? | PubMed ID: 18591393 | Fulltext

Altered hepatic triglyceride content after partial hepatectomy without impaired liver regeneration in multiple murine genetic models.

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Newberry EP, Kennedy SM, Xie Y, Luo J, Stanley SE, Semenkovich CF, Crooke RM, Graham MJ, and Davidson NO

Hepatology (Baltimore, Md.), 2008 Jun 19 - Who cited this? | PubMed ID: 18697204 | Fulltext

Niemann-Pick C1 protects against atherosclerosis in mice via regulation of macrophage intracellular cholesterol trafficking.

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Zhang JR, Coleman T, Langmade SJ, Scherrer DE, Lane L, Lanier MH, Feng C, Sands MS, Schaffer JE, Semenkovich CF, and Ory DS

The Journal of clinical investigation, 2008 May 15 - Who cited this? | PubMed ID: 18483620 | Fulltext

Lysosomal dysfunction results in altered energy balance.

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Woloszynek JC, Coleman T, Semenkovich CF, and Sands MS

The Journal of biological chemistry 282(49):35765-71, 2007 Dec 7 - Who cited this? | PubMed ID: 17911106 | Fulltext

Macrophage beta3 integrin suppresses hyperlipidemia-induced inflammation by modulating TNFalpha expression.

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Schneider JG, Zhu Y, Coleman T, and Semenkovich CF

Arteriosclerosis, thrombosis, and vascular biology 27(12):2699-706, 2007 Dec - Who cited this? | PubMed ID: 17951320 | Fulltext

Respiratory uncoupling in skeletal muscle delays death and diminishes age-related disease.

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Gates AC, Bernal-Mizrachi C, Chinault SL, Feng C, Schneider JG, Coleman T, Malone JP, Townsend RR, Chakravarthy MV, and Semenkovich CF

Cell metabolism 6(6):497-505, 2007 Dec - Who cited this? | PubMed ID: 18054318 | Fulltext

Absence of peroxisome proliferator-activated receptor-alpha abolishes hypertension and attenuates atherosclerosis in the Tsukuba hypertensive mouse.

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Tordjman KM, Semenkovich CF, Coleman T, Yudovich R, Bak S, Osher E, Vechoropoulos M, and Stern N

Hypertension 50(5):945-51, 2007 Nov - Who cited this? | PubMed ID: 17909121 | Fulltext

Retention of low-density lipoprotein in atherosclerotic lesions of the mouse: evidence for a role of lipoprotein lipase.

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Gustafsson M, Levin M, Skålén K, Perman J, Fridén V, Jirholt P, Olofsson SO, Fazio S, Linton MF, Semenkovich CF, Olivecrona G, and Borén J

Circulation research 101(8):777-83, 2007 Oct 12 - Who cited this? | PubMed ID: 17761930 | Fulltext

Macrophage expression of peroxisome proliferator-activated receptor-alpha reduces atherosclerosis in low-density lipoprotein receptor-deficient mice.

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Babaev VR, Ishiguro H, Ding L, Yancey PG, Dove DE, Kovacs WJ, Semenkovich CF, Fazio S, and Linton MF

Circulation 116(12):1404-12, 2007 Sep 18 - Who cited this? | PubMed ID: 17724261 | Fulltext

Attenuated free cholesterol loading-induced apoptosis but preserved phospholipid composition of peritoneal macrophages from mice that do not express group VIA phospholipase A2.

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Bao S, Li Y, Lei X, Wohltmann M, Jin W, Bohrer A, Semenkovich CF, Ramanadham S, Tabas I, and Turk J

The Journal of biological chemistry 282(37):27100-14, 2007 Sep 14 - Who cited this? | PubMed ID: 17627946 | Fulltext

Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis.

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Chakravarthy MV, Zhu Y, López M, Yin L, Wozniak DF, Coleman T, Hu Z, Wolfgang M, Vidal-Puig A, Lane MD, and Semenkovich CF

The Journal of clinical investigation 117(9):2539, 2007 Sep - Who cited this? | PubMed ID: 17694178 | Fulltext

Bone weighs in on obesity.

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Semenkovich CF and Teitelbaum SL

Cell 130(3):409-11, 2007 Aug 10 - Who cited this? | PubMed ID: 17693252 | Fulltext

Grb2 is required for atherosclerotic lesion formation.

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Proctor BM, Ren J, Chen Z, Schneider JG, Coleman T, Lupu TS, Semenkovich CF, and Muslin AJ

Arteriosclerosis, thrombosis, and vascular biology 27(6):1361-7, 2007 Jun - Who cited this? | PubMed ID: 17363695 | Fulltext

The ABCs of beta-cell dysfunction in type 2 diabetes.

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Chakravarthy MV and Semenkovich CF

Nature medicine 13(3):241-2, 2007 Mar - Who cited this? | PubMed ID: 17342111 | Fulltext

An afferent vagal nerve pathway links hepatic PPARalpha activation to glucocorticoid-induced insulin resistance and hypertension.

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Bernal-Mizrachi C, Xiaozhong L, Yin L, Knutsen RH, Howard MJ, Arends JJ, Desantis P, Coleman T, and Semenkovich CF

Cell metabolism 5(2):91-102, 2007 Feb - Who cited this? | PubMed ID: 17276352 | Fulltext

Mechanisms underlying the resistance to diet-induced obesity in germ-free mice.

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Bäckhed F, Manchester JK, Semenkovich CF, and Gordon JI

Proceedings of the National Academy of Sciences of the United States of America 104(3):979, 2007 Jan 16 - Who cited this? | PubMed ID: 17210919 | Fulltext

PPARalpha activation elevates blood pressure and does not correct glucocorticoid-induced insulin resistance in humans.

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Subramanian S, DeRosa MA, Bernal-Mizrachi C, Laffely N, Cade WT, Yarasheski KE, Cryer PE, and Semenkovich CF

American journal of physiology. Endocrinology and metabolism 291(6):E1365-71, 2006 Dec - Who cited this? | PubMed ID: 16868225 | Fulltext

ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome.

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Schneider JG, Finck BN, Ren J, Standley KN, Takagi M, Maclean KH, Bernal-Mizrachi C, Muslin AJ, Kastan MB, and Semenkovich CF

Cell metabolism 4(5):377, 2006 Nov - Who cited this? | PubMed ID: 17084711 | Fulltext

Insulin resistance and atherosclerosis.

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Semenkovich CF

The Journal of clinical investigation 116(7):1813-22, 2006 Jul - Who cited this? | PubMed ID: 16823479 | Fulltext

Fast predators or fast food, the fit still survive.

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Bernal-Mizrachi C and Semenkovich CF

Nature medicine 12(1):46-7; discussion 47, 2006 Jan - Who cited this? | PubMed ID: 16397564 | Fulltext

PPARalpha: savior or savage?.

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Schneider JG and Semenkovich CF

Cell metabolism 2(6):341, 2005 Dec - Who cited this? | PubMed ID: 16330317 | Fulltext

Targeted intestinal overexpression of the immediate early gene tis7 in transgenic mice increases triglyceride absorption and adiposity.

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Wang Y, Iordanov H, Swietlicki EA, Wang L, Fritsch C, Coleman T, Semenkovich CF, Levin MS, and Rubin DC

The Journal of biological chemistry 280(41):34764-75, 2005 Oct 14 - Who cited this? | PubMed ID: 16085642 | Fulltext

Maternal genotype affects adult offspring lipid, obesity, and diabetes phenotypes in LGXSM recombinant inbred strains.

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Jarvis JP, Kenney-Hunt J, Ehrich TH, Pletscher LS, Semenkovich CF, and Cheverud JM

Journal of lipid research 46(8):1692-702, 2005 Aug - Who cited this? | PubMed ID: 15897602 | Fulltext

TZDs and diabetes: testing the waters.

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Semenkovich CF

Nature medicine 11(8):822-4, 2005 Aug - Who cited this? | PubMed ID: 16079871 | Fulltext

Fine-mapping gene-by-diet interactions on chromosome 13 in a LG/J x SM/J murine model of obesity.

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Ehrich TH, Hrbek T, Kenney-Hunt JP, Pletscher LS, Wang B, Semenkovich CF, and Cheverud JM

Diabetes 54(6):1863-72, 2005 Jun - Who cited this? | PubMed ID: 15919810 | Fulltext

Vascular respiratory uncoupling increases blood pressure and atherosclerosis.

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Bernal-Mizrachi C, Gates AC, Weng S, Imamura T, Knutsen RH, DeSantis P, Coleman T, Townsend RR, Muglia LJ, and Semenkovich CF

Nature 435(7041):502, 2005 May 26 - Who cited this? | PubMed ID: 15917810 | Fulltext

"New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis.

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Chakravarthy MV, Pan Z, Zhu Y, Tordjman K, Schneider JG, Coleman T, Turk J, and Semenkovich CF

Cell metabolism 1(5):309, 2005 May - Who cited this? | PubMed ID: 16054078 | Fulltext

Alterations in thigh subcutaneous adipose tissue gene expression in protease inhibitor-based highly active antiretroviral therapy.

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Chaparro J, Reeds DN, Wen W, Xueping E, Klein S, Semenkovich CF, Bae KT, Quirk EK, Powderly WG, Yarasheski KE, and Li E

Metabolism: clinical and experimental 54(5):561-7, 2005 May - Who cited this? | PubMed ID: 15877283 | Fulltext

PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.

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Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, Boudina S, Courtois M, Wozniak DF, Sambandam N, Bernal-Mizrachi C, Chen Z, Holloszy JO, Medeiros DM, Schmidt RE, Saffitz JE, Abel ED,

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PLoS biology 3(4):e101, 2005 Apr - Who cited this? | PubMed ID: 15760270 | Fulltext

Pancreatic beta-cell lipoprotein lipase independently regulates islet glucose metabolism and normal insulin secretion.

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Pappan KL, Pan Z, Kwon G, Marshall CA, Coleman T, Goldberg IJ, McDaniel ML, and Semenkovich CF

The Journal of biological chemistry 280(10):9023-9, 2005 Mar 11 - Who cited this? | PubMed ID: 15637076 | Fulltext

A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes.

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Finck BN, Bernal-Mizrachi C, Han DH, Coleman T, Sambandam N, LaRiviere LL, Holloszy JO, Semenkovich CF, and Kelly DP

Cell metabolism 1(2):133, 2005 Feb - Who cited this? | PubMed ID: 16054054 | Fulltext

Quantitative trait loci for obesity- and diabetes-related traits and their dietary responses to high-fat feeding in LGXSM recombinant inbred mouse strains.

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Cheverud JM, Ehrich TH, Hrbek T, Kenney JP, Pletscher LS, and Semenkovich CF

Diabetes 53(12):3328-36, 2004 Dec - Who cited this? | PubMed ID: 15561968 | Fulltext

The gut microbiota as an environmental factor that regulates fat storage.

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Bäckhed F, Ding H, Wang T, Hooper LV, Koh GY, Nagy A, Semenkovich CF, and Gordon JI

Proceedings of the National Academy of Sciences of the United States of America 101(44):15718, 2004 Nov 2 - Who cited this? | PubMed ID: 15505215 | Fulltext

Genetic evidence for discordance between obesity- and diabetes-related traits in the LGXSM recombinant inbred mouse strains.

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Cheverud JM, Ehrich TH, Kenney JP, Pletscher LS, and Semenkovich CF

Diabetes 53(10):2700, 2004 Oct - Who cited this? | PubMed ID: 15448104 | Fulltext

Numerous transcriptional alterations in liver persist after short-term enzyme-replacement therapy in a murine model of mucopolysaccharidosis type VII.

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Woloszynek JC, Roberts M, Coleman T, Vogler C, Sly W, Semenkovich CF, and Sands MS

The Biochemical journal 379(Pt 2):461-9, 2004 Apr 15 - Who cited this? | PubMed ID: 14705966 | Fulltext

UCP-mediated energy depletion in skeletal muscle increases glucose transport despite lipid accumulation and mitochondrial dysfunction.

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Han DH, Nolte LA, Ju JS, Coleman T, Holloszy JO, and Semenkovich CF

American journal of physiology. Endocrinology and metabolism 286(3):E347-53, 2004 Mar - Who cited this? | PubMed ID: 14613927 | Fulltext

Fatty acid metabolism and vascular disease.

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Semenkovich CF

Trends in cardiovascular medicine 14(2):72-6, 2004 Feb - Who cited this? | PubMed ID: 15030793 | Fulltext

Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association.

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Nesto RW, Bell D, Bonow RO, Fonseca V, Grundy SM, Horton ES, Le Winter M, Porte D, Semenkovich CF, Smith S, Young LH, and Kahn R

Diabetes care 27(1):256-63, 2004 Jan - Who cited this? | PubMed ID: 14693998 | Fulltext

Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. October 7, 2003.

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Nesto RW, Bell D, Bonow RO, Fonseca V, Grundy SM, Horton ES, Le Winter M, Porte D, Semenkovich CF, Smith S, Young LH, Kahn R, American Heart Association , and American Diabetes Association

Circulation 108(23):2941-8, 2003 Dec 9 - Who cited this? | PubMed ID: 14662691 | Fulltext

Alpha2beta1 integrin and development of atherosclerosis in a mouse model: assessment of risk.

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Grenache DG, Coleman T, Semenkovich CF, Santoro SA, and Zutter MM

Arteriosclerosis, thrombosis, and vascular biology 23(11):2104-9, 2003 Nov 1 - Who cited this? | PubMed ID: 14512368 | Fulltext

Visceral adiposity, C-peptide levels, and low lipase activities predict HIV-dyslipidemia.

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Yarasheski KE, Tebas P, Claxton S, Marin D, Coleman T, Powderly WG, and Semenkovich CF

American journal of physiology. Endocrinology and metabolism 285(4):E899-905, 2003 Oct - Who cited this? | PubMed ID: 12837664 | Fulltext

Skeletal muscle overexpression of nuclear respiratory factor 1 increases glucose transport capacity.

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Baar K, Song Z, Semenkovich CF, Jones TE, Han DH, Nolte LA, Ojuka EO, Chen M, and Holloszy JO

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 17(12):1666-73, 2003 Sep - Who cited this? | PubMed ID: 12958173 | Fulltext

Transgenic mice expressing lipoprotein lipase in adipose tissue. Absence of the proximal 3'-untranslated region causes translational upregulation.

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Hensley LL, Ranganathan G, Wagner EM, Wells BD, Daniel JC, Vu D, Semenkovich CF, Zechner R, and Kern PA

The Journal of biological chemistry 278(35):32702-9, 2003 Aug 29 - Who cited this? | PubMed ID: 12796491 | Fulltext

Dexamethasone induction of hypertension and diabetes is PPAR-alpha dependent in LDL receptor-null mice.

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Bernal-Mizrachi C, Weng S, Feng C, Finck BN, Knutsen RH, Leone TC, Coleman T, Mecham RP, Kelly DP, and Semenkovich CF

Nature medicine 9(8):1069-75, 2003 Aug - Who cited this? | PubMed ID: 12847522 | Fulltext

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