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Papers authored by Seiki M

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Mint3 Enhances the Activity of Hypoxia-inducible Factor-1 (HIF-1) in Macrophages by Suppressing the Activity of Factor Inhibiting HIF-1.

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Sakamoto T and Seiki M

The Journal of biological chemistry 284(44):30350-9, 2009 Oct 30 - Who cited this? | PubMed ID: 19726677 | Fulltext

A novel protein associated with membrane-type 1 matrix metalloproteinase binds p27(kip1) and regulates RhoA activation, actin remodeling, and matrigel invasion.

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Hoshino D, Tomari T, Nagano M, Koshikawa N, and Seiki M

The Journal of biological chemistry 284(40):27315-26, 2009 Oct 2 - Who cited this? | PubMed ID: 19654316 | Fulltext

Identification and characterization of Lutheran blood group glycoprotein as a new substrate of membrane-type 1 matrix metalloproteinase 1 (MT1-MMP): a systemic whole cell analysis of MT1-MMP-associating proteins in A431 cells.

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Niiya D, Egawa N, Sakamoto T, Kikkawa Y, Shinkawa T, Isobe T, Koshikawa N, and Seiki M

The Journal of biological chemistry 284(40):27360-9, 2009 Oct 2 - Who cited this? | PubMed ID: 19667067 | Fulltext

High throughput analysis of proteins associating with a proinvasive MT1-MMP in human malignant melanoma A375 cells.

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Tomari T, Koshikawa N, Uematsu T, Shinkawa T, Hoshino D, Egawa N, Isobe T, and Seiki M

Cancer science 100(7):1284-90, 2009 Jul - Who cited this? | PubMed ID: 19432894 | Fulltext

Cytoplasmic tail of MT1-MMP regulates macrophage motility independently from its protease activity.

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Sakamoto T and Seiki M

Genes to cells : devoted to molecular & cellular mechanisms 14(5):617-26, 2009 May - Who cited this? | PubMed ID: 19371380 | Fulltext

Membrane type 1 matrix metalloproteinase is a crucial promoter of synovial invasion in human rheumatoid arthritis.

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Miller MC, Manning HB, Jain A, Troeberg L, Dudhia J, Essex D, Sandison A, Seiki M, Nanchahal J, Nagase H, and Itoh Y

Arthritis and rheumatism 60(3):686-97, 2009 Mar - Who cited this? | PubMed ID: 19248098 | Fulltext

Spontaneous transformation of human granulosa cell tumours into an aggressive phenotype: a metastasis model cell line.

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Imai M, Muraki M, Takamatsu K, Saito H, Seiki M, and Takahashi Y

BMC cancer 8(1):319, 2008 Nov 4 - Who cited this? | PubMed ID: 18980698 | Fulltext

The second dimer interface of MT1-MMP, the transmembrane domain, is essential for ProMMP-2 activation on the cell surface.

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Itoh Y, Ito N, Nagase H, and Seiki M

The Journal of biological chemistry 283(19):13053, 2008 May 9 - Who cited this? | PubMed ID: 18337248 | Fulltext

Development of a new tracking tool for the human monomeric laminin-gamma 2 chain in vitro and in vivo.

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Koshikawa N, Minegishi T, Nabeshima K, and Seiki M

Cancer research 68(2):530, 2008 Jan 15 - Who cited this? | PubMed ID: 18199549 | Fulltext

Establishment of an MT4-MMP-deficient mouse strain representing an efficient tracking system for MT4-MMP/MMP-17 expression in vivo using beta-galactosidase.

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Rikimaru A, Komori K, Sakamoto T, Ichise H, Yoshida N, Yana I, and Seiki M

Genes to cells : devoted to molecular & cellular mechanisms 12(9):1091-100, 2007 Sep - Who cited this? | PubMed ID: 17825051 | Fulltext

Crosstalk between neovessels and mural cells directs the site-specific expression of MT1-MMP to endothelial tip cells.

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Yana I, Sagara H, Takaki S, Takatsu K, Nakamura K, Nakao K, Katsuki M, Taniguchi S, Aoki T, Sato H, Weiss SJ, and Seiki M

Journal of cell science 120(Pt 9):1607, 2007 May 1 - Who cited this? | PubMed ID: 17405818 | Fulltext

Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice.

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Taniwaki K, Fukamachi H, Komori K, Ohtake Y, Nonaka T, Sakamoto T, Shiomi T, Okada Y, Itoh T, Itohara S, Seiki M, and Yana I

Cancer research 67(9):4311-9, 2007 May 1 - Who cited this? | PubMed ID: 17483344 | Fulltext

Regulated nucleo-cytoplasmic shuttling of human aci-reductone dioxygenase (hADI1) and its potential role in mRNA processing.

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Gotoh I, Uekita T, and Seiki M

Genes to cells : devoted to molecular & cellular mechanisms 12(1):105-17, 2007 Jan - Who cited this? | PubMed ID: 17212658 | Fulltext

Membrane type 1 matrix metalloproteinase (MT1-MMP/MMP-14) cleaves and releases a 22-kDa extracellular matrix metalloproteinase inducer (EMMPRIN) fragment from tumor cells.

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Egawa N, Koshikawa N, Tomari T, Nabeshima K, Isobe T, and Seiki M

The Journal of biological chemistry 281(49):37576-85, 2006 Dec 8 - Who cited this? | PubMed ID: 17050542 | Fulltext

Negative regulation of osteoclastogenesis by ectodomain shedding of receptor activator of NF-kappaB ligand.

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Hikita A, Yana I, Wakeyama H, Nakamura M, Kadono Y, Oshima Y, Nakamura K, Seiki M, and Tanaka S

The Journal of biological chemistry 281(48):36846-55, 2006 Dec 1 - Who cited this? | PubMed ID: 17018528 | Fulltext

Cell surface collagenolysis requires homodimerization of the membrane-bound collagenase MT1-MMP.

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Itoh Y, Ito N, Nagase H, Evans RD, Bird SA, and Seiki M

Molecular biology of the cell 17(12):5390-9, 2006 Dec - Who cited this? | PubMed ID: 17050733 | Fulltext

Multifunctional roles of MT1-MMP in myofiber formation and morphostatic maintenance of skeletal muscle.

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Ohtake Y, Tojo H, and Seiki M

Journal of cell science 119(Pt 18):3822-32, 2006 Sep 15 - Who cited this? | PubMed ID: 16926191 | Fulltext

Membrane-type 1 matrix metalloproteinase modulates focal adhesion stability and cell migration.

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Takino T, Watanabe Y, Matsui M, Miyamori H, Kudo T, Seiki M, and Sato H

Experimental cell research 312(8):1381-9, 2006 May 1 - Who cited this? | PubMed ID: 16473349 | Fulltext

Type I collagen abrogates the clathrin-mediated internalization of membrane type 1 matrix metalloproteinase (MT1-MMP) via the MT1-MMP hemopexin domain.

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Lafleur MA, Mercuri FA, Ruangpanit N, Seiki M, Sato H, and Thompson EW

The Journal of biological chemistry 281(10):6826-40, 2006 Mar 10 - Who cited this? | PubMed ID: 16407177 | Fulltext

MT1-MMP: a potent modifier of pericellular microenvironment.

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Itoh Y and Seiki M

Journal of cellular physiology 206(1):1-8, 2006 Jan - Who cited this? | PubMed ID: 15920734 | Fulltext

Palmitoylation at Cys574 is essential for MT1-MMP to promote cell migration.

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Anilkumar N, Uekita T, Couchman JR, Nagase H, Seiki M, and Itoh Y

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19(10):1326, 2005 Aug - Who cited this? | PubMed ID: 15946988 | Fulltext

Competitive disruption of the tumor-promoting function of membrane type 1 matrix metalloproteinase/matrix metalloproteinase-14 in vivo.

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Nonaka T, Nishibashi K, Itoh Y, Yana I, and Seiki M

Molecular cancer therapeutics 4(8):1157, 2005 Aug - Who cited this? | PubMed ID: 16093431 | Fulltext

Membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1 (MTCBP-1) acts as an eukaryotic aci-reductone dioxygenase (ARD) in the methionine salvage pathway.

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Hirano W, Gotoh I, Uekita T, and Seiki M

Genes to cells : devoted to molecular & cellular mechanisms 10(6):565, 2005 Jun - Who cited this? | PubMed ID: 15938715 | Fulltext

Matrix metalloproteinase expression and function during fin regeneration in zebrafish: analysis of MT1-MMP, MMP2 and TIMP2.

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Bai S, Thummel R, Godwin AR, Nagase H, Itoh Y, Li L, Evans R, McDermott J, Seiki M, and Sarras MP

Matrix biology : journal of the International Society for Matrix Biology 24(4):247-60, 2005 Jun - Who cited this? | PubMed ID: 15935631 | Fulltext

Impaired alveolization in mice deficient in membrane-type matrix metalloproteinase 1 (MT1-MMP).

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Irie K, Komori K, Seiki M, Tsuruga E, Sakakura Y, Kaku T, and Yajima T

Medical molecular morphology 38(1):43-6, 2005 Mar - Who cited this? | PubMed ID: 16158179 | Fulltext

CD44 binding through the hemopexin-like domain is critical for its shedding by membrane-type 1 matrix metalloproteinase.

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Suenaga N, Mori H, Itoh Y, and Seiki M

Oncogene 24(5):859-68, 2005 Jan 27 - Who cited this? | PubMed ID: 15558018 | Fulltext

Membrane-type matrix metalloproteinase-1 (MT1-MMP) is a processing enzyme for human laminin gamma 2 chain.

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Koshikawa N, Minegishi T, Sharabi A, Quaranta V, and Seiki M

The Journal of biological chemistry 280(1):88-93, 2005 Jan 7 - Who cited this? | PubMed ID: 15525652 | Fulltext

'Do experiments that will help solve clinical problems'. An interview with Professor Seiki Matsuno by Martin E. Fernandez-Zapico.

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Seiki M

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 5(4-5):312-3, 2005 - Who cited this? | PubMed ID: 15980660 | Fulltext

Expression and localization of matrix metalloproteinases (MT1-MMP, MMP-2) and tissue inhibitor of metalloproteinase-2 (TIMP-2) during synepitheliochorial placentation of goats (Capra hircus).

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Uekita T, Yamanouchi K, Sato H, Tojo H, Seiki M, and Tachi C

Placenta 25(10):810-9, 2004 Nov - Who cited this? | PubMed ID: 15451196 | Fulltext

Expression and localization of membrane-type-1 matrix metalloproteinase, CD 44, and laminin-5gamma2 chain during colorectal carcinoma tumor progression.

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Murai S, Umemiya T, Seiki M, and Harigaya K

Virchows Archiv : an international journal of pathology 445(3):271-8, 2004 Sep - Who cited this? | PubMed ID: 15517370 | Fulltext

IRSp53/Eps8 complex is important for positive regulation of Rac and cancer cell motility/invasiveness.

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Funato Y, Terabayashi T, Suenaga N, Seiki M, Takenawa T, and Miki H

Cancer research 64(15):5237-44, 2004 Aug 1 - Who cited this? | PubMed ID: 15289329 | Fulltext

Mutations in two matrix metalloproteinase genes, MMP-2 and MT1-MMP, are synthetic lethal in mice.

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Oh J, Takahashi R, Adachi E, Kondo S, Kuratomi S, Noma A, Alexander DB, Motoda H, Okada A, Seiki M, Itoh T, Itohara S, Takahashi C, and Noda M

Oncogene 23(29):5041-8, 2004 Jun 24 - Who cited this? | PubMed ID: 15064723 | Fulltext

MT1-MMP: an enzyme with multidimensional regulation.

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Itoh Y and Seiki M

Trends in biochemical sciences 29(6):285-9, 2004 Jun - Who cited this? | PubMed ID: 15276180 | Fulltext

Activation of pro-MMP-2 mediated by MT1-MMP in human salivary gland carcinomas: possible regulation of pro-MMP-2 activation by TIMP-2.

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Kayano K, Shimada T, Shinomiya T, Nakai S, Hisa Y, Aoki T, Seiki M, and Okada Y

The Journal of pathology 202(4):403-11, 2004 Apr - Who cited this? | PubMed ID: 15095267 | Fulltext

Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down-regulated in tumors.

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Uekita T, Gotoh I, Kinoshita T, Itoh Y, Sato H, Shiomi T, Okada Y, and Seiki M

The Journal of biological chemistry 279(13):12734-43, 2004 Mar 26 - Who cited this? | PubMed ID: 14718544 | Fulltext

Constitutive and induced CD44 shedding by ADAM-like proteases and membrane-type 1 matrix metalloproteinase.

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Nakamura H, Suenaga N, Taniwaki K, Matsuki H, Yonezawa K, Fujii M, Okada Y, and Seiki M

Cancer research 64(3):876-82, 2004 Feb 1 - Who cited this? | PubMed ID: 14871815 | Fulltext

Membrane type 1 matrix metalloproteinase regulates collagen-dependent mitogen-activated protein/extracellular signal-related kinase activation and cell migration.

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Takino T, Miyamori H, Watanabe Y, Yoshioka K, Seiki M, and Sato H

Cancer research 64(3):1044-9, 2004 Feb 1 - Who cited this? | PubMed ID: 14871836 | Fulltext

Absence of mechanical allodynia and Abeta-fiber sprouting after sciatic nerve injury in mice lacking membrane-type 5 matrix metalloproteinase.

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Komori K, Nonaka T, Okada A, Kinoh H, Hayashita-Kinoh H, Yoshida N, Yana I, and Seiki M

FEBS letters 557(1-3):125-8, 2004 Jan 16 - Who cited this? | PubMed ID: 14741353 | Fulltext

Differences between scirrhous and non-scirrhous human gastric carcinomas from the aspect of proMMP-2 activation regulated by TIMP-3.

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Yokoyama T, Nakamura H, Otani Y, Kubota T, Fujimoto N, Seiki M, Kitajima M, and Okada Y

Clinical & experimental metastasis 21(3):223-33, 2004 - Who cited this? | PubMed ID: 15387372 | Fulltext

Ageladine A: an antiangiogenic matrixmetalloproteinase inhibitor from the marine sponge Agelas nakamurai.

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Fujita M, Nakao Y, Matsunaga S, Seiki M, Itoh Y, Yamashita J, Van Soest RW, and Fusetani N

Journal of the American Chemical Society 125(51):15700-1, 2003 Dec 24 - Who cited this? | PubMed ID: 14677933 | Fulltext

Monoclonal antibodies with defined recognition sequences in the stem region of CD44: detection of differential glycosylation of CD44 between tumor and stromal cells in tissue.

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Matsuki H, Yonezawa K, Obata K, Iwata K, Nakamura H, Okada Y, and Seiki M

Cancer research 63(23):8278-83, 2003 Dec 1 - Who cited this? | PubMed ID: 14678986 | Fulltext

Sequence-specific silencing of MT1-MMP expression suppresses tumor cell migration and invasion: importance of MT1-MMP as a therapeutic target for invasive tumors.

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Ueda J, Kajita M, Suenaga N, Fujii K, and Seiki M

Oncogene 22(54):8716-22, 2003 Nov 27 - Who cited this? | PubMed ID: 14647466 | Fulltext

Clusterin, an abundant serum factor, is a possible negative regulator of MT6-MMP/MMP-25 produced by neutrophils.

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Matsuda A, Itoh Y, Koshikawa N, Akizawa T, Yana I, and Seiki M

The Journal of biological chemistry 278(38):36350-7, 2003 Sep 19 - Who cited this? | PubMed ID: 12860995 | Fulltext

Cleavage of metastasis suppressor gene product KiSS-1 protein/metastin by matrix metalloproteinases.

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Takino T, Koshikawa N, Miyamori H, Tanaka M, Sasaki T, Okada Y, Seiki M, and Sato H

Oncogene 22(30):4617-26, 2003 Jul 24 - Who cited this? | PubMed ID: 12879005 | Fulltext

Roles of pericellular proteolysis by membrane type-1 matrix metalloproteinase in cancer invasion and angiogenesis.

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Seiki M and Yana I

Cancer science 94(7):569-74, 2003 Jul - Who cited this? | PubMed ID: 12841863 | Fulltext

Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion.

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Seiki M

Cancer letters 194(1):1-11, 2003 May 8 - Who cited this? | PubMed ID: 12706853 | Fulltext

Tetraspanin CD63 promotes targeting and lysosomal proteolysis of membrane-type 1 matrix metalloproteinase.

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Takino T, Miyamori H, Kawaguchi N, Uekita T, Seiki M, and Sato H

Biochemical and biophysical research communications 304(1):160-6, 2003 Apr 25 - Who cited this? | PubMed ID: 12705901 | Fulltext

Callysponginol sulfate A, an MT1-MMP inhibitor isolated from the marine sponge Callyspongia truncata.

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Fujita M, Nakao Y, Matsunaga S, van Soest RW, Itoh Y, Seiki M, and Fusetani N

Journal of natural products 66(4):569-71, 2003 Apr - Who cited this? | PubMed ID: 12713420 | Fulltext

[Matrix metalloproteinases; the past, present, and future].

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Yana I and Seiki M

Nippon Shokakibyo Gakkai zasshi The Japanese journal of gastro-enterology 100(2):144-51, 2003 Feb - Who cited this? | PubMed ID: 12649853 | Fulltext

Membrane-type 1 matrix metalloproteinase and cell migration.

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Seiki M, Mori H, Kajita M, Uekita T, and Itoh Y

Biochemical Society symposium(70):253-62, 2003 - Who cited this? | PubMed ID: 14587298 | Fulltext

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