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Papers authored by Scheffler IE

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Mitochondrial p32 Protein Is a Critical Regulator of Tumor Metabolism via Maintenance of Oxidative Phosphorylation.

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Fogal V, Richardson AD, Karmali PP, Scheffler IE, Smith JW, and Ruoslahti E

Molecular and cellular biology 30(6):1303-18, 2010 Mar - Who cited this? | PubMed ID: 20100866 | Fulltext

A novel NDUFA1 mutation leads to a progressive mitochondrial complex I-specific neurodegenerative disease.

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Potluri P, Davila A, Ruiz-Pesini E, Mishmar D, O'Hearn S, Hancock S, Simon M, Scheffler IE, Wallace DC, and Procaccio V

Molecular genetics and metabolism 96(4):189-95, 2009 Apr - Who cited this? | PubMed ID: 19185523 | Fulltext

Suppression of Tumor Growth In vivo by the Mitocan {alpha}-tocopheryl Succinate Requires Respiratory Complex II.

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Dong LF, Freeman R, Liu J, Zobalova R, Marin-Hernandez A, Stantic M, Rohlena J, Valis K, Rodriguez-Enriquez S, Butcher B, Goodwin J, Brunk UT, Witting PK, Moreno-Sanchez R, Scheffler IE, Ralph SJ,

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Clinical cancer research : an official journal of the American Association for Cancer Research 15(5):1593-600, 2009 Mar 1 - Who cited this? | PubMed ID: 19223492 | Fulltext

Alpha-tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II.

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Dong LF, Low P, Dyason JC, Wang XF, Prochazka L, Witting PK, Freeman R, Swettenham E, Valis K, Liu J, Zobalova R, Turanek J, Spitz DR, Domann FE, Scheffler IE, Ralph SJ,

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Oncogene 27(31):4324-35, 2008 Jul 17 - Who cited this? | PubMed ID: 18372923 | Fulltext

Investigations of the potential effects of phosphorylation of the MWFE and ESSS subunits on complex I activity and assembly.

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Yadava N, Potluri P, and Scheffler IE

The international journal of biochemistry & cell biology 40(3):447-60, 2008 - Who cited this? | PubMed ID: 17931954 | Fulltext

Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense.

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Sonoda J, Laganière J, Mehl IR, Barish GD, Chong LW, Li X, Scheffler IE, Mock DC, Bataille AR, Robert F, Lee CH, Giguère V, and Evans RM

Genes & development 21(15):1909, 2007 Aug 1 - Who cited this? | PubMed ID: 17671090 | Fulltext

Cyanide detoxification by the cobalamin precursor cobinamide.

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Broderick KE, Potluri P, Zhuang S, Scheffler IE, Sharma VS, Pilz RB, and Boss GR

Experimental biology and medicine (Maywood, N.J.) 231(5):641-9, 2006 May - Who cited this? | PubMed ID: 16636313 | Fulltext

Molecular genetics of complex I-deficient Chinese hamster cell lines.

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Scheffler IE, Yadava N, and Potluri P

Biochimica et biophysica acta 1659(2-3):160-71, 2004 Dec 6 - Who cited this? | PubMed ID: 15576048 | Fulltext

The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase).

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Potluri P, Yadava N, and Scheffler IE

European journal of biochemistry / FEBS 271(15):3265-73, 2004 Aug - Who cited this? | PubMed ID: 15265046 | Fulltext

Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain.

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Ricci JE, Muñoz-Pinedo C, Fitzgerald P, Bailly-Maitre B, Perkins GA, Yadava N, Scheffler IE, Ellisman MH, and Green DR

Cell 117(6):773-86, 2004 Jun 11 - Who cited this? | PubMed ID: 15186778 | Fulltext

Import and orientation of the MWFE protein in mitochondrial NADH-ubiquinone oxidoreductase.

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Yadava N and Scheffler IE

Mitochondrion 4(1):1-12, 2004 Jun - Who cited this? | PubMed ID: 16120368 | Fulltext

Development and characterization of a conditional mitochondrial complex I assembly system.

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Yadava N, Houchens T, Potluri P, and Scheffler IE

The Journal of biological chemistry 279(13):12406-13, 2004 Mar 26 - Who cited this? | PubMed ID: 14722084 | Fulltext

The tumor suppressor cybL, a component of the respiratory chain, mediates apoptosis induction.

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Albayrak T, Scherhammer V, Schoenfeld N, Braziulis E, Mund T, Bauer MK, Scheffler IE, and Grimm S

Molecular biology of the cell 14(8):3082-96, 2003 Aug - Who cited this? | PubMed ID: 12925748 | Fulltext

The role of the 5' untranslated region (UTR) in glucose-dependent mRNA decay.

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de la Cruz BJ, Prieto S, and Scheffler IE

Yeast (Chichester, England) 19(10):887-902, 2002 Jul - Who cited this? | PubMed ID: 12112242 | Fulltext

Species-specific and mutant MWFE proteins. Their effect on the assembly of a functional mammalian mitochondrial complex I.

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Yadava N, Potluri P, Smith EN, Bisevac A, and Scheffler IE

The Journal of biological chemistry 277(24):21221, 2002 Jun 14 - Who cited this? | PubMed ID: 11937507 | Fulltext

Mitochondria make a come back.

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Scheffler IE

Advanced drug delivery reviews 49(1-2):3-26, 2001 Jul 2 - Who cited this? | PubMed ID: 11377800 | Fulltext

Molecular genetics of the mammalian NADH-ubiquinone oxidoreductase.

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Scheffler IE and Yadava N

Journal of bioenergetics and biomembranes 33(3):243-50, 2001 Jun - Who cited this? | PubMed ID: 11695834 | Fulltext

A century of mitochondrial research: achievements and perspectives.

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Scheffler IE

Mitochondrion 1(1):3-31, 2001 Jun - Who cited this? | PubMed ID: 16120266 | Fulltext

Combined and individual mitochondrial HSP60 and HSP10 expression in cardiac myocytes protects mitochondrial function and prevents apoptotic cell deaths induced by simulated ischemia-reoxygenation.

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Lin KM, Lin B, Lian IY, Mestril R, Scheffler IE, and Dillmann WH

Circulation 103(13):1787-92, 2001 Apr 3 - Who cited this? | PubMed ID: 11282911 | Fulltext

Glucose-regulated turnover of mRNA and the influence of poly(A) tail length on half-life.

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Prieto S, de la Cruz BJ, and Scheffler IE

The Journal of biological chemistry 275(19):14155-66, 2000 May 12 - Who cited this? | PubMed ID: 10799492 | Fulltext

The NDUFA1 gene product (MWFE protein) is essential for activity of complex I in mammalian mitochondria.

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Au HC, Seo BB, Matsuno-Yagi A, Yagi T, and Scheffler IE

Proceedings of the National Academy of Sciences of the United States of America 96(8):4354, 1999 Apr 13 - Who cited this? | PubMed ID: 10200266 | Fulltext

Targeted integration of a dominant neo(R) marker into a 2- to 3-Mb human minichromosome and transfer between cells.

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Au HC, Mascarello JT, and Scheffler IE

Cytogenetics and cell genetics 86(3-4):194-203, 1999 - Who cited this? | PubMed ID: 10575205 | Fulltext

Control of mRNA turnover as a mechanism of glucose repression in Saccharomyces cerevisiae.

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Scheffler IE, de la Cruz BJ, and Prieto S

The international journal of biochemistry & cell biology 30(11):1175-93, 1998 Nov - Who cited this? | PubMed ID: 9839444 | Fulltext

Molecular remedy of complex I defects: rotenone-insensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae mitochondria restores the NADH oxidase activity of complex I-deficient mammalian cells.

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Seo BB, Kitajima-Ihara T, Chan EK, Scheffler IE, Matsuno-Yagi A, and Yagi T

Proceedings of the National Academy of Sciences of the United States of America 95(16):9167-71, 1998 Aug 4 - Who cited this? | PubMed ID: 9689052 | Fulltext

Characterization of the human SDHC gene encoding of the integral membrane proteins of succinate-quinone oxidoreductase in mitochondria.

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Elbehti-Green A, Au HC, Mascarello JT, Ream-Robinson D, and Scheffler IE

Gene 213(1-2):133-40, 1998 Jun 15 - Who cited this? | PubMed ID: 9714607 | Fulltext

Promoter analysis of the human succinate dehydrogenase iron-protein gene--both nuclear respiratory factors NRF-1 and NRF-2 are required.

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Au HC and Scheffler IE

European journal of biochemistry / FEBS 251(1-2):164-74, 1998 Jan 15 - Who cited this? | PubMed ID: 9492280 | Fulltext

Molecular genetics of succinate:quinone oxidoreductase in eukaryotes.

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Scheffler IE

Progress in nucleic acid research and molecular biology 60:267-315, 1998 - Who cited this? | PubMed ID: 9594577 | Fulltext

Co-operation of the 5' and 3' untranslated regions of ornithine decarboxylase mRNA and inhibitory role of its 3' untranslated region in regulating the translational efficiency of hybrid RNA species via cellular factor.

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Lorenzini EC and Scheffler IE

The Biochemical journal 326 ( Pt 2):361-7, 1997 Sep 1 - Who cited this? | PubMed ID: 9291106 | Fulltext

A respiration-deficient Chinese hamster cell line with a defect in mitochondrial protein synthesis: rapid turnover of some mitochondrial transcripts.

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Au HC and Scheffler IE

Somatic cell and molecular genetics 23(1):27-35, 1997 Jan - Who cited this? | PubMed ID: 9217999 | Fulltext

Genetic analysis of glucose regulation in saccharomyces cerevisiae: control of transcription versus mRNA turnover.

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Cereghino GP and Scheffler IE

The EMBO journal 15(2):363-74, 1996 Jan 15 - Who cited this? | PubMed ID: 8617211 | Fulltext

A Chinese hamster mutant cell line with a defect in the integral membrane protein CII-3 of complex II of the mitochondrial electron transport chain.

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Oostveen FG, Au HC, Meijer PJ, and Scheffler IE

The Journal of biological chemistry 270(44):26104-8, 1995 Nov 3 - Who cited this? | PubMed ID: 7592812 | Fulltext

Glucose-dependent turnover of the mRNAs encoding succinate dehydrogenase peptides in Saccharomyces cerevisiae: sequence elements in the 5' untranslated region of the Ip mRNA play a dominant role.

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Cereghino GP, Atencio DP, Saghbini M, Beiner J, and Scheffler IE

Molecular biology of the cell 6(9):1125-43, 1995 Sep - Who cited this? | PubMed ID: 8534911 | Fulltext

Structural organization of the gene encoding the human iron-sulfur subunit of succinate dehydrogenase.

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Au HC, Ream-Robinson D, Bellew LA, Broomfield PL, Saghbini M, and Scheffler IE

Gene 159(2):249-53, 1995 Jul 4 - Who cited this? | PubMed ID: 7622059 | Fulltext

Regulation of mammalian ornithine decarboxylase. Studies on the induction of the enzyme by hypotonic stress.

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Lövkvist-Wallström E, Stjernborg-Ulvsbäck L, Scheffler IE, and Persson L

European journal of biochemistry / FEBS 231(1):40-4, 1995 Jul 1 - Who cited this? | PubMed ID: 7628482 | Fulltext

Isolation and characterization of HL-60 cells resistant to nitroprusside-induced differentiation.

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Pilz RB, Berjis M, Idriss SD, Scheele JS, Suhasini M, Gao L, Scheffler IE, and Boss GR

The Journal of biological chemistry 269(51):32155-61, 1994 Dec 23 - Who cited this? | PubMed ID: 7798212 | Fulltext

Characterization of the gene encoding the iron-sulfur protein subunit of succinate dehydrogenase from Drosophila melanogaster.

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Au HC and Scheffler IE

Gene 149(2):261-5, 1994 Nov 18 - Who cited this? | PubMed ID: 7958999 | Fulltext

Studies on the assembly of complex II in yeast mitochondria using chimeric human/yeast genes for the iron-sulfur protein subunit.

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Saghbini M, Broomfield PL, and Scheffler IE

Biochemistry 33(1):159-65, 1994 Jan 11 - Who cited this? | PubMed ID: 8286334 | Fulltext

The gene for the iron sulfur protein of succinate dehydrogenase (SDH-IP) maps to human chromosome 1p35-36.1.

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Leckschat S, Ream-Robinson D, and Scheffler IE

Somatic cell and molecular genetics 19(5):505-11, 1993 Sep - Who cited this? | PubMed ID: 8291026 | Fulltext

The C-terminus of the succinate dehydrogenase IP peptide of Saccharomyces cerevisiae is significant for assembly of complex II.

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Schmidt DM, Saghbini M, and Scheffler IE

Biochemistry 31(36):8442-8, 1992 Sep 15 - Who cited this? | PubMed ID: 1390628 | Fulltext

Control of mRNA turnover as a mechanism of glucose repression in Saccharomyces cerevisiae.

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Lombardo A, Cereghino GP, and Scheffler IE

Molecular and cellular biology 12(7):2941-8, 1992 Jul - Who cited this? | PubMed ID: 1620107 | Fulltext

The 5'- and 3'-untranslated regions of ornithine decarboxylase mRNA affect the translational efficiency.

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Grens A and Scheffler IE

The Journal of biological chemistry 265(20):11810-6, 1990 Jul 15 - Who cited this? | PubMed ID: 2365700 | Fulltext

Cloning and characterization of the iron-sulfur subunit gene of succinate dehydrogenase from Saccharomyces cerevisiae.

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Lombardo A, Carine K, and Scheffler IE

The Journal of biological chemistry 265(18):10419-23, 1990 Jun 25 - Who cited this? | PubMed ID: 2191948 | Fulltext

Molecular and genetic characterization of an ornithine decarboxylase-deficient Chinese hamster cell line.

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Pilz RB, Steglich C, and Scheffler IE

The Journal of biological chemistry 265(15):8880-6, 1990 May 25 - Who cited this? | PubMed ID: 1692838 | Fulltext

Nucleotide sequence of the Chinese hamster ornithine decarboxylase gene.

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Grens A, Steglich C, Pilz R, and Scheffler IE

Nucleic acids research 17(24):10497, 1989 Dec 25 - Who cited this? | PubMed ID: 2602162 | Fulltext

Isolation and characterization of a Saccharomyces cerevisiae mutant with a disrupted gene for the IP subunit of succinate dehydrogenase.

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Lombardo A and Scheffler IE

The Journal of biological chemistry 264(32):18874-7, 1989 Nov 15 - Who cited this? | PubMed ID: 2681203 | Fulltext

Molecular characterization of human minichromosomes with centromere from chromosome 1 in human-hamster hybrid cells.

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Carine K, Jacquemin-Sablon A, Waltzer E, Mascarello J, and Scheffler IE

Somatic cell and molecular genetics 15(5):445-60, 1989 Sep - Who cited this? | PubMed ID: 2781415 | Fulltext

Use of the DNA polymerase chain reaction for homology probing: isolation of partial cDNA or genomic clones encoding the iron-sulfur protein of succinate dehydrogenase from several species.

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Gould SJ, Subramani S, and Scheffler IE

Proceedings of the National Academy of Sciences of the United States of America 86(6):1934-8, 1989 Mar - Who cited this? | PubMed ID: 2494655 | Fulltext

Molecular characterization of human minichromosomes in Chinese hamster/human somatic cell hybrids.

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Scheffler IE and Carine K

Progress in clinical and biological research 318:19-31, 1989 - Who cited this? | PubMed ID: 2576309 | Fulltext

Steady-state and nuclear run-on analyses of transcription in a temperature-sensitive Chinese hamster cell mutant with a defect in RNA metabolism.

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Slezynger TC and Scheffler IE

Somatic cell and molecular genetics 14(5):439-59, 1988 Sep - Who cited this? | PubMed ID: 2459782 | Fulltext

Temperature-sensitive Chinese hamster cell mutant with a defect in glycoprotein synthesis: accumulation of the EGF receptor in the endoplasmic reticulum and the role of the glucose-regulated protein GRP78.

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Feige JJ, Keller GA, and Scheffler IE

Journal of cellular physiology 136(1):33-42, 1988 Jul - Who cited this? | PubMed ID: 3294237 | Fulltext

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