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Papers authored by Sauer RT

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Structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine.

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Glynn SE, Martin A, Nager AR, Baker TA, and Sauer RT

Cell 139(4):744-56, 2009 Nov 13 - Who cited this? | PubMed ID: 19914167 | Fulltext

Degrons in protein substrates program the speed and operating efficiency of the AAA+ Lon proteolytic machine.

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Gur E and Sauer RT

Proceedings of the National Academy of Sciences of the United States of America 106(44):18503-8, 2009 Nov 3 - Who cited this? | PubMed ID: 19841274 | Fulltext

OMP Peptides Activate the DegS Stress-Sensor Protease by a Relief of Inhibition Mechanism.

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Sohn J, Grant RA, and Sauer RT

Structure (London, England : 1993) 17(10):1411-21, 2009 Oct 14 - Who cited this? | PubMed ID: 19836340 | Fulltext

Engineering Synthetic Adaptors and Substrates for Controlled ClpXP Degradation.

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Davis JH, Baker TA, and Sauer RT

The Journal of biological chemistry 284(33):21848-55, 2009 Aug 14 - Who cited this? | PubMed ID: 19549779 | Fulltext

Polypeptide Translocation by the AAA+ ClpXP Protease Machine.

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Barkow SR, Levchenko I, Baker TA, and Sauer RT

Chemistry & biology 16(6):605-12, 2009 Jun 26 - Who cited this? | PubMed ID: 19549599 | Fulltext

Molecular basis of substrate selection by the N-end rule adaptor protein ClpS.

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Román-Hernández G, Grant RA, Sauer RT, and Baker TA

Proceedings of the National Academy of Sciences of the United States of America 106(22):8888-93, 2009 Jun 2 - Who cited this? | PubMed ID: 19451643 | Fulltext

Control of Pseudomonas aeruginosa AlgW protease cleavage of MucA by peptide signals and MucB.

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Cezairliyan BO and Sauer RT

Molecular microbiology 72(2):368-79, 2009 Apr - Who cited this? | PubMed ID: 19298369 | Fulltext

Analyzing the Interaction of RseA and RseB, the Two Negative Regulators of the {sigma}E Envelope Stress Response, Using a Combined Bioinformatic and Experimental Strategy.

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Ahuja N, Korkin D, Chaba R, Cezairliyan BO, Sauer RT, Kim KK, and Gross CA

The Journal of biological chemistry 284(8):5403-13, 2009 Feb 20 - Who cited this? | PubMed ID: 19103591 | Fulltext

OMP Peptides Modulate the Activity of DegS Protease by Differential Binding to Active and Inactive Conformations.

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Sohn J and Sauer RT

Molecular cell 33(1):64-74, 2009 Jan 16 - Who cited this? | PubMed ID: 19150428 | Fulltext

Revisiting the mechanism of macrolide-antibiotic resistance mediated by ribosomal protein L22.

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Moore SD and Sauer RT

Proceedings of the National Academy of Sciences of the United States of America 105(47):18261-6, 2008 Nov 25 - Who cited this? | PubMed ID: 19015512 | Fulltext

The molecular basis of N-end rule recognition.

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Wang KH, Roman-Hernandez G, Grant RA, Sauer RT, and Baker TA

Molecular cell 32(3):406-14, 2008 Nov 7 - Who cited this? | PubMed ID: 18995838 | Fulltext

Pore loops of the AAA+ ClpX machine grip substrates to drive translocation and unfolding.

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Martin A, Baker TA, and Sauer RT

Nature structural & molecular biology 15(11):1147-51, 2008 Nov - Who cited this? | PubMed ID: 18931677 | Fulltext

Evolution of the ssrA degradation tag in Mycoplasma: Specificity switch to a different protease.

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Gur E and Sauer RT

Proceedings of the National Academy of Sciences of the United States of America 105(42):16113-8, 2008 Oct 21 - Who cited this? | PubMed ID: 18852454 | Fulltext

Recognition of misfolded proteins by Lon, a AAA+ protease.

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Gur E and Sauer RT

Genes & development 22(16):2267-77, 2008 Aug 15 - Who cited this? | PubMed ID: 18708584 | Fulltext

Forced extraction of targeted components from complex macromolecular assemblies.

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Moore SD, Baker TA, and Sauer RT

Proceedings of the National Academy of Sciences of the United States of America, 2008 Aug 11 - Who cited this? | PubMed ID: 18695246 | Fulltext

Asymmetric nucleotide transactions of the HslUV protease.

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Yakamavich JA, Baker TA, and Sauer RT

Journal of molecular biology 380(5):946, 2008 Jul 25 - Who cited this? | PubMed ID: 18582897 | Fulltext

Tuning the strength of a bacterial N-end rule degradation signal.

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Wang KH, Oakes ES, Sauer RT, and Baker TA

The Journal of biological chemistry, 2008 Jun 11 - Who cited this? | PubMed ID: 18550545 | Fulltext

Unique contacts direct high-priority recognition of the tetrameric Mu transposase-DNA complex by the AAA+ unfoldase ClpX.

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Abdelhakim AH, Oakes EC, Sauer RT, and Baker TA

Molecular cell 30(1):39, 2008 Apr 11 - Who cited this? | PubMed ID: 18406325 | Fulltext

Distinct structural elements of the adaptor ClpS are required for regulating degradation by ClpAP.

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Hou JY, Sauer RT, and Baker TA

Nature structural & molecular biology 15(3):288, 2008 Mar - Who cited this? | PubMed ID: 18297088 | Fulltext

Diverse pore loops of the AAA+ ClpX machine mediate unassisted and adaptor-dependent recognition of ssrA-tagged substrates.

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Martin A, Baker TA, and Sauer RT

Molecular cell 29(4):441, 2008 Feb 29 - Who cited this? | PubMed ID: 18313382 | Fulltext

Protein unfolding by a AAA+ protease is dependent on ATP-hydrolysis rates and substrate energy landscapes.

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Martin A, Baker TA, and Sauer RT

Nature structural & molecular biology 15(2):139, 2008 Feb - Who cited this? | PubMed ID: 18223658 | Fulltext

Allosteric activation of DegS, a stress sensor PDZ protease.

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Sohn J, Grant RA, and Sauer RT

Cell 131(3):572, 2007 Nov 2 - Who cited this? | PubMed ID: 17981123 | Fulltext

Structure and substrate specificity of an SspB ortholog: design implications for AAA+ adaptors.

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Chien P, Grant RA, Sauer RT, and Baker TA

Structure (London, England : 1993) 15(10):1296, 2007 Oct - Who cited this? | PubMed ID: 17937918 | Fulltext

Distinct static and dynamic interactions control ATPase-peptidase communication in a AAA+ protease.

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Martin A, Baker TA, and Sauer RT

Molecular cell 27(1):41, 2007 Jul 6 - Who cited this? | PubMed ID: 17612489 | Fulltext

Direct and adaptor-mediated substrate recognition by an essential AAA+ protease.

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Chien P, Perchuk BS, Laub MT, Sauer RT, and Baker TA

Proceedings of the National Academy of Sciences of the United States of America 104(16):6590, 2007 Apr 17 - Who cited this? | PubMed ID: 17420450 | Fulltext

Altered tethering of the SspB adaptor to the ClpXP protease causes changes in substrate delivery.

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McGinness KE, Bolon DN, Kaganovich M, Baker TA, and Sauer RT

The Journal of biological chemistry 282(15):11465, 2007 Apr 13 - Who cited this? | PubMed ID: 17317664 | Fulltext

Inhibition of regulated proteolysis by RseB.

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Cezairliyan BO and Sauer RT

Proceedings of the National Academy of Sciences of the United States of America 104(10):3771, 2007 Mar 6 - Who cited this? | PubMed ID: 17360428 | Fulltext

ClpS modulates but is not essential for bacterial N-end rule degradation.

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Wang KH, Sauer RT, and Baker TA

Genes & development 21(4):403-8, 2007 Feb 15 - Who cited this? | PubMed ID: 17322400 | Fulltext

Altered specificity of a AAA+ protease.

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Farrell CM, Baker TA, and Sauer RT

Molecular cell 25(1):161, 2007 Jan 12 - Who cited this? | PubMed ID: 17218279 | Fulltext

The tmRNA system for translational surveillance and ribosome rescue.

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Moore SD and Sauer RT

Annual review of biochemistry 76:101, 2007 - Who cited this? | PubMed ID: 17291191 | Fulltext

ATP-dependent proteases of bacteria: recognition logic and operating principles.

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Baker TA and Sauer RT

Trends in biochemical sciences 31(12):647, 2006 Dec - Who cited this? | PubMed ID: 17074491 | Fulltext

Engineering controllable protein degradation.

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McGinness KE, Baker TA, and Sauer RT

Molecular cell 22(5):701, 2006 Jun 9 - Who cited this? | PubMed ID: 16762842 | Fulltext

Proteomic profiling of ClpXP substrates after DNA damage reveals extensive instability within SOS regulon.

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Neher SB, Villén J, Oakes EC, Bakalarski CE, Sauer RT, Gygi SP, and Baker TA

Molecular cell 22(2):193, 2006 Apr 21 - Who cited this? | PubMed ID: 16630889 | Fulltext

Sequence determinants of a conformational switch in a protein structure.

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Anderson TA, Cordes MH, and Sauer RT

Proceedings of the National Academy of Sciences of the United States of America 102(51):18344-9, 2005 Dec 20 - Who cited this? | PubMed ID: 16344489 | Fulltext

Rebuilt AAA + motors reveal operating principles for ATP-fuelled machines.

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Martin A, Baker TA, and Sauer RT

Nature 437(7062):1115-20, 2005 Oct 20 - Who cited this? | PubMed ID: 16237435 | Fulltext

Ribosome rescue: tmRNA tagging activity and capacity in Escherichia coli.

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Moore SD and Sauer RT

Molecular microbiology 58(2):456, 2005 Oct - Who cited this? | PubMed ID: 16194232 | Fulltext

Specificity versus stability in computational protein design.

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Bolon DN, Grant RA, Baker TA, and Sauer RT

Proceedings of the National Academy of Sciences of the United States of America 102(36):12724, 2005 Sep 6 - Who cited this? | PubMed ID: 16129838 | Fulltext

Cytoplasmic degradation of ssrA-tagged proteins.

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Farrell CM, Grossman AD, and Sauer RT

Molecular microbiology 57(6):1750, 2005 Sep - Who cited this? | PubMed ID: 16135238 | Fulltext

Asymmetric interactions of ATP with the AAA+ ClpX6 unfoldase: allosteric control of a protein machine.

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Hersch GL, Burton RE, Bolon DN, Baker TA, and Sauer RT

Cell 121(7):1017, 2005 Jul 1 - Who cited this? | PubMed ID: 15989952 | Fulltext

Versatile modes of peptide recognition by the AAA+ adaptor protein SspB.

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Levchenko I, Grant RA, Flynn JM, Sauer RT, and Baker TA

Nature structural & molecular biology 12(6):520, 2005 Jun - Who cited this? | PubMed ID: 15880122 | Fulltext

Nucleotide-dependent substrate recognition by the AAA+ HslUV protease.

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Burton RE, Baker TA, and Sauer RT

Nature structural & molecular biology 12(3):245-51, 2005 Mar - Who cited this? | PubMed ID: 15696175 | Fulltext

Consolidating critical binding determinants by noncyclic rearrangement of protein secondary structure.

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Tabtiang RK, Cezairliyan BO, Grant RA, Cochrane JC, and Sauer RT

Proceedings of the National Academy of Sciences of the United States of America 102(7):2305-9, 2005 Feb 15 - Who cited this? | PubMed ID: 15689399 | Fulltext

Partitioning between unfolding and release of native domains during ClpXP degradation determines substrate selectivity and partial processing.

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Kenniston JA, Baker TA, and Sauer RT

Proceedings of the National Academy of Sciences of the United States of America 102(5):1390-5, 2005 Feb 1 - Who cited this? | PubMed ID: 15671177 | Fulltext

Nucleotide-dependent substrate handoff from the SspB adaptor to the AAA+ ClpXP protease.

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Bolon DN, Grant RA, Baker TA, and Sauer RT

Molecular cell 16(3):343, 2004 Nov 5 - Who cited this? | PubMed ID: 15525508 | Fulltext

Sculpting the proteome with AAA(+) proteases and disassembly machines.

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Sauer RT, Bolon DN, Burton BM, Burton RE, Flynn JM, Grant RA, Hersch GL, Joshi SA, Kenniston JA, Levchenko I, Neher SB, Oakes ES, Siddiqui SM, Wah DA, and Baker TA

Cell 119(1):9, 2004 Oct 1 - Who cited this? | PubMed ID: 15454077 | Fulltext

Modulating substrate choice: the SspB adaptor delivers a regulator of the extracytoplasmic-stress response to the AAA+ protease ClpXP for degradation.

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Flynn JM, Levchenko I, Sauer RT, and Baker TA

Genes & development 18(18):2292, 2004 Sep 15 - Who cited this? | PubMed ID: 15371343 | Fulltext

Ribosomal protein S1 binds mRNA and tmRNA similarly but plays distinct roles in translation of these molecules.

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McGinness KE and Sauer RT

Proceedings of the National Academy of Sciences of the United States of America 101(37):13454, 2004 Sep 14 - Who cited this? | PubMed ID: 15340139 | Fulltext

Signaling degradation.

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Kenniston JA and Sauer RT

Nature structural & molecular biology 11(9):800-2, 2004 Sep - Who cited this? | PubMed ID: 15332074 | Fulltext

SspB delivery of substrates for ClpXP proteolysis probed by the design of improved degradation tags.

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Hersch GL, Baker TA, and Sauer RT

Proceedings of the National Academy of Sciences of the United States of America 101(33):12136, 2004 Aug 17 - Who cited this? | PubMed ID: 15297609 | Fulltext

Computational and experimental probes of symmetry mismatches in the Arc repressor-DNA complex.

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Spector S, Sauer RT, and Tidor B

Journal of molecular biology 340(2):253-61, 2004 Jul 2 - Who cited this? | PubMed ID: 15201050 | Fulltext

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