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Papers authored by Salazar DE

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Pharmacokinetics and pharmacodynamics of prasugrel in subjects with moderate liver disease.

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Small DS, Farid NA, Li YG, Ernest CS, Winters KJ, Salazar DE, and Payne CD

Journal of clinical pharmacy and therapeutics 34(5):575-83, 2009 Oct - Who cited this? | PubMed ID: 19744013 | Fulltext

Prasugrel pharmacokinetics and pharmacodynamics in subjects with moderate renal impairment and end-stage renal disease.

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Small DS, Wrishko RE, Ernest CS, Ni L, Winters KJ, Farid NA, Li YG, Brandt JT, Salazar DE, Borel AG, Kles KA, and Payne CD

Journal of clinical pharmacy and therapeutics 34(5):585-94, 2009 Oct - Who cited this? | PubMed ID: 19744014 | Fulltext

Quantitative structure-property relationships modeling to predict in vitro and in vivo binding of drugs to the bile sequestrant, colesevelam (welchol).

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Walker JR, Brown K, Rohatagi S, Bathala MS, Xu C, Wickremasingha PK, Salazar DE, and Mager DE

Journal of clinical pharmacology 49(10):1185-95, 2009 Oct - Who cited this? | PubMed ID: 19783712 | Fulltext

Population Pharmacokinetic Analyses to Evaluate the Influence of Intrinsic and Extrinsic Factors on Exposure of Prasugrel Active Metabolite in TRITON-TIMI 38.

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Wrishko RE, Ernest CS, Small DS, Li YG, Weerakkody GJ, Riesmeyer JR, Macias WL, Rohatagi S, Salazar DE, Antman EM, Wiviott SD, Braunwald E, and Ni L

Journal of clinical pharmacology 49(8):984-98, 2009 Aug - Who cited this? | PubMed ID: 19546250 | Fulltext

Effect of rifampin on the pharmacokinetics and pharmacodynamics of prasugrel in healthy male subjects.

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Farid NA, Jakubowski JA, Payne CD, Li YG, Jin Y, Ernest II CS, Winters KJ, Brandt JT, Salazar DE, and Small DS

Current medical research and opinion 25(8):1821-9, 2009 Aug - Who cited this? | PubMed ID: 19530977 | Fulltext

An open-label study of aripiprazole: pharmacokinetics, tolerability, and effectiveness in children and adolescents with conduct disorder.

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Findling RL, Kauffman R, Sallee FR, Salazar DE, Sahasrabudhe V, Kollia G, Kornhauser DM, Vachharajani NN, Assuncao-Talbott S, Mallikaarjun S, Iwamoto T, McQuade RD, Boulton DW, and Blumer J

Journal of child and adolescent psychopharmacology 19(4):431-9, 2009 Aug - Who cited this? | PubMed ID: 19702495 | Fulltext

Effect of Age on the Pharmacokinetics and Pharmacodynamics of Prasugrel during Multiple Dosing: An Open-Label, Single-Sequence, Clinical Trial.

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Small DS, Wrishko RE, Ernest CS, Ni L, Winters KJ, Farid NA, Li YG, Salazar DE, and Payne CD

Drugs & aging 26(9):781-90, 2009 - Who cited this? | PubMed ID: 19728751 | Fulltext

Effect of atorvastatin on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in healthy subjects.

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Farid NA, Small DS, Payne CD, Jakubowski JA, Brandt JT, Li YG, Ernest CS, Salazar DE, Konkoy CS, and Winters KJ

Pharmacotherapy 28(12):1483-94, 2008 Dec - Who cited this? | PubMed ID: 19025429 | Fulltext

Model-Based Development of a PPAR{gamma} Agonist, Rivoglitazone, to Aid Dose Selection and Optimize Clinical Trial Designs.

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Rohatagi S, Carrothers TJ, Jin J, Jusko WJ, Khariton T, Walker J, Truitt K, and Salazar DE

Journal of clinical pharmacology 48(12):1420-9, 2008 Dec - Who cited this? | PubMed ID: 18936283 | Fulltext

Population pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in aspirin-treated patients with stable coronary artery disease.

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Ernest CS, Small DS, Rohatagi S, Salazar DE, Wallentin L, Winters KJ, and Wrishko RE

Journal of pharmacokinetics and pharmacodynamics 35(6):593-618, 2008 Dec - Who cited this? | PubMed ID: 19023649 | Fulltext

Pharmacokinetics of amlodipine and olmesartan after administration of amlodipine besylate and olmesartan medoxomil in separate dosage forms and as a fixed-dose combination.

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Rohatagi S, Lee J, Shenouda M, Haworth S, Bathala MS, Allison M, Rubets I, Heyrman R, Noveck R, and Salazar DE

Journal of clinical pharmacology 48(11):1309-22, 2008 Nov - Who cited this? | PubMed ID: 18974285 | Fulltext

Effect of ranitidine on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel.

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Small DS, Farid NA, Li YG, Ernest CS, Payne CD, Salazar DE, and Winters KJ

Current medical research and opinion 24(8):2251-7, 2008 Aug - Who cited this? | PubMed ID: 18786302 | Fulltext

Pain relief model for a COX-2 inhibitor in patients with postoperative dental pain.

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Rohatagi S, Kastrissios H, Sasahara K, Truitt K, Moberly JB, Wada R, and Salazar DE

British journal of clinical pharmacology 66(1):60-70, 2008 Jul - Who cited this? | PubMed ID: 18522627 | Fulltext

Switching directly to prasugrel from clopidogrel results in greater inhibition of platelet aggregation in aspirin-treated subjects.

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Payne CD, Li YG, Brandt JT, Jakubowski JA, Small DS, Farid NA, Salazar DE, and Winters KJ

Platelets 19(4):275-81, 2008 Jun - Who cited this? | PubMed ID: 18569863 | Fulltext

Effects of the proton pump inhibitor lansoprazole on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel.

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Small DS, Farid NA, Payne CD, Weerakkody GJ, Li YG, Brandt JT, Salazar DE, and Winters KJ

Journal of clinical pharmacology 48(4):475-84, 2008 Apr - Who cited this? | PubMed ID: 18303127 | Fulltext

The use of the VerifyNow P2Y12 point-of-care device to monitor platelet function across a range of P2Y(12) inhibition levels following prasugrel and clopidogrel administration.

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Jakubowski JA, Payne CD, Li YG, Brandt JT, Small DS, Farid NA, Salazar DE, and Winters KJ

Thrombosis and haemostasis 99(2):409-15, 2008 Feb - Who cited this? | PubMed ID: 18278193 | Fulltext

Prasugrel, a New Thienopyridine Antiplatelet Drug, Weakly Inhibits Cytochrome P450 2B6 in Humans.

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Farid NA, Payne CD, Ernest CS, Li YG, Winters KJ, Salazar DE, and Small DS

Journal of clinical pharmacology 48(1):53-9, 2008 Jan - Who cited this? | PubMed ID: 18094219 | Fulltext

A comparison of the antiplatelet effects of prasugrel and high-dose clopidogrel as assessed by VASP-phosphorylation and light transmission aggregometry.

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Jakubowski JA, Payne CD, Li YG, Farid NA, Brandt JT, Small DS, Salazar DE, and Winters KJ

Thrombosis and haemostasis 99(1):215-22, 2008 Jan - Who cited this? | PubMed ID: 18217157 | Fulltext

Increased active metabolite formation explains the greater platelet inhibition with prasugrel compared to high-dose clopidogrel.

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Payne CD, Li YG, Small DS, Ernest CS, Farid NA, Jakubowski JA, Brandt JT, Salazar DE, and Winters KJ

Journal of cardiovascular pharmacology 50(5):555-62, 2007 Nov - Who cited this? | PubMed ID: 18030066 | Fulltext

Pharmacokinetics of aripiprazole and concomitant carbamazepine.

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Citrome L, Macher JP, Salazar DE, Mallikaarjun S, and Boulton DW

Journal of clinical psychopharmacology 27(3):279-83, 2007 Jun - Who cited this? | PubMed ID: 17502775 | Fulltext

Cytochrome P450 3A inhibition by ketoconazole affects prasugrel and clopidogrel pharmacokinetics and pharmacodynamics differently.

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Farid NA, Payne CD, Small DS, Winters KJ, Ernest CS, Brandt JT, Darstein C, Jakubowski JA, and Salazar DE

Clinical pharmacology and therapeutics 81(5):735-41, 2007 May - Who cited this? | PubMed ID: 17361128 | Fulltext

Pharmacokinetics of a newly identified active metabolite of buspirone after administration of buspirone over its therapeutic dose range.

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Dockens RC, Salazar DE, Fulmor IE, Wehling M, Arnold ME, and Croop R

Journal of clinical pharmacology 46(11):1308-12, 2006 Nov - Who cited this? | PubMed ID: 17050795 | Fulltext

The effect of AST-120 on the single-dose pharmacokinetics of losartan and losartan acid (E-3174) in healthy subjects.

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Marier JF, Guilbaud R, Kambhampati SR, Mathew P, Moberly J, Lee J, and Salazar DE

Journal of clinical pharmacology 46(3):310-20, 2006 Mar - Who cited this? | PubMed ID: 16490807 | Fulltext

Effect of repeated oral administrations of the oral adsorbent AST-120 on serum creatinine and other markers of renal function. A randomized controlled study in patients with chronic kidney disease.

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Marier JF, Lee J, Kambhampati SR, Galitz L, Vargas R, Moberly J, and Salazar DE

American journal of nephrology 26(2):136-41, 2006 - Who cited this? | PubMed ID: 16549905 | Fulltext

Pharmacokinetics of aripiprazole and concomitant lithium and valproate.

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Citrome L, Josiassen R, Bark N, Salazar DE, and Mallikaarjun S

Journal of clinical pharmacology 45(1):89-93, 2005 Jan - Who cited this? | PubMed ID: 15601809 | Fulltext

Pharmacokinetics, tolerability, and safety of aripiprazole following multiple oral dosing in normal healthy volunteers.

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Mallikaarjun S, Salazar DE, and Bramer SL

Journal of clinical pharmacology 44(2):179-87, 2004 Feb - Who cited this? | PubMed ID: 14747427 | Fulltext

Brasofensine treatment for Parkinson's disease in combination with levodopa/carbidopa.

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Frackiewicz EJ, Jhee SS, Shiovitz TM, Webster J, Topham C, Dockens RC, Whigan D, Salazar DE, and Cutler NR

The Annals of pharmacotherapy 36(2):225-30, 2002 Feb - Who cited this? | PubMed ID: 11847938 | Fulltext

Pharmacokinetics and tolerability of buspirone during oral administration to children and adolescents with anxiety disorder and normal healthy adults.

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Salazar DE, Frackiewicz EJ, Dockens R, Kollia G, Fulmor IE, Tigel PD, Uderman HD, Shiovitz TM, Sramek JJ, and Cutler NR

Journal of clinical pharmacology 41(12):1351-8, 2001 Dec - Who cited this? | PubMed ID: 11762563 | Fulltext

Loratadine and terfenadine interaction with nefazodone: Both antihistamines are associated with QTc prolongation.

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Abernethy DR, Barbey JT, Franc J, Brown KS, Feirrera I, Ford N, and Salazar DE

Clinical pharmacology and therapeutics 69(3):96-103, 2001 Mar - Who cited this? | PubMed ID: 11240972 | Fulltext

Carbamazepine-nefazodone interaction in healthy subjects.

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Laroudie C, Salazar DE, Cosson JP, Cheuvart B, Istin B, Girault J, Ingrand I, and Decourt JP

Journal of clinical psychopharmacology 20(1):46-53, 2000 Feb - Who cited this? | PubMed ID: 10653208 | Fulltext

Central nervous system pharmacokinetics of psychiatric drugs.

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Salazar DE and Fischman AJ

Journal of clinical pharmacology Suppl:10S-12S, 1999 Aug - Who cited this? | PubMed ID: 10434241 | Fulltext

Pharmacokinetics and pharmacodynamics of avitriptan during intravenous administration in healthy subjects.

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Sharma A, Jusko WJ, Fulmor IE, Norton J, Uderman HD, and Salazar DE

Journal of clinical pharmacology 39(7):685-94, 1999 Jul - Who cited this? | PubMed ID: 10392323 | Fulltext

A double-blind, randomized, crossover assessment of blood pressure following administration of avitriptan, sumatriptan, or placebo to patients with mild to moderate hypertension.

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Jhee SS, Salazar DE, Ford NF, Fulmor IE, Sramek JJ, and Cutler NR

Cephalalgia : an international journal of headache 19(2):95-9, 1999 Mar - Who cited this? | PubMed ID: 10214534 | Fulltext

Pharmacokinetic evaluation of co-administration of nefazodone and lithium in healthy subjects.

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Laroudie C, Salazar DE, Cosson JP, Cheuvart B, Istin B, Girault J, Ingrand I, and Decourt JP

European journal of clinical pharmacology 54(12):923-8, 1999 Feb - Who cited this? | PubMed ID: 10192752 | Fulltext

Pharmacokinetics and pharmacodynamics of avitriptan in patients with migraine after oral dosing.

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Cutler NR, Salazar DE, Jhee SS, Fulmor IE, Ford N, Smith RA, and Sramek JJ

Headache 38(6):446-52, 1998 Jun - Who cited this? | PubMed ID: 9664749 | Fulltext

Monitoring of acute migraine attacks: placebo response and safety data.

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Jhee SS, Salazar DE, Ford NF, Fulmor IE, Sramek JJ, and Cutler NR

Headache 38(1):35-8, 1998 Jan - Who cited this? | PubMed ID: 9505001 | Fulltext

A pharmacokinetic-pharmacodynamic model of d-sotalol Q-Tc prolongation during intravenous administration to healthy subjects.

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Salazar DE, Much DR, Nichola PS, Seibold JR, Shindler D, and Slugg PH

Journal of clinical pharmacology 37(9):799-809, 1997 Sep - Who cited this? | PubMed ID: 9549633 | Fulltext

Evaluation of cerebral pharmacokinetics of the novel antidepressant drug, BMS-181101, by positron emission tomography.

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Christian BT, Livni E, Babich JW, Alpert NM, Dischino DD, Ruediger E, Salazar DE, Ford NF, and Fischman AJ

The Journal of pharmacology and experimental therapeutics 279(1):325-31, 1996 Oct - Who cited this? | PubMed ID: 8859010 | Fulltext

Coadministration of nefazodone and benzodiazepines: III. A pharmacokinetic interaction study with alprazolam.

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Greene DS, Salazar DE, Dockens RC, Kroboth P, and Barbhaiya RH

Journal of clinical psychopharmacology 15(6):399-408, 1995 Dec - Who cited this? | PubMed ID: 8748428 | Fulltext

Coadministration of nefazodone and benzodiazepines: IV. A pharmacokinetic interaction study with lorazepam.

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Greene DS, Salazar DE, Dockens RC, Kroboth P, and Barbhaiya RH

Journal of clinical psychopharmacology 15(6):409-16, 1995 Dec - Who cited this? | PubMed ID: 8748429 | Fulltext

Absorption and presystemic metabolism of nefazodone administered at different regions in the gastrointestinal tract of humans.

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Marathe PH, Salazar DE, Greene DS, Brennan J, Shukla UA, and Barbhaiya RH

Pharmaceutical research 12(11):1716-21, 1995 Nov - Who cited this? | PubMed ID: 8592675 | Fulltext

Pharmacokinetic and pharmacodynamic evaluation during coadministration of nefazodone and propranolol in healthy men.

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Salazar DE, Marathe PH, Fulmor IE, Lee JS, Raymond RH, and Uderman HD

Journal of clinical pharmacology 35(11):1109-18, 1995 Nov - Who cited this? | PubMed ID: 8626885 | Fulltext

Coadministration of nefazodone and benzodiazepines: I. Pharmacodynamic assessment.

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Kroboth PD, Folan MM, Lush RM, Chaikin PC, Shukla UA, Barbhaiya R, and Salazar DE

Journal of clinical psychopharmacology 15(5):306-19, 1995 Oct - Who cited this? | PubMed ID: 8830061 | Fulltext

Pharmacokinetic and pharmacodynamic evaluation of warfarin and nefazodone coadministration in healthy subjects.

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Salazar DE, Dockens RC, Milbrath RL, Raymond RH, Fulmor IE, Chaikin PC, and Uderman HD

Journal of clinical pharmacology 35(7):730-8, 1995 Jul - Who cited this? | PubMed ID: 7560254 | Fulltext

Obesity decreases hepatic glutathione concentrations and markedly potentiates allyl alcohol-induced periportal necrosis in the overfed rat.

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Salazar DE, Sorge CL, Jordan SW, and Corcoran GB

International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 18(1):25-33, 1994 Jan - Who cited this? | PubMed ID: 8130812 | Fulltext

Obesity as a risk factor in drug-induced organ injury. V. Toxicokinetics of gentamicin in the obese overfed rat.

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Salazar DE, Schentag JJ, and Corcoran GB

Drug metabolism and disposition: the biological fate of chemicals 20(3):402-6, 1992 - Who cited this? | PubMed ID: 1355715 | Fulltext

Two-compartment basophil cell trafficking model for methylprednisolone pharmacodynamics.

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Wald JA, Salazar DE, Chen HY, and Jusko WJ

Journal of pharmacokinetics and biopharmaceutics 19(5):521-36, 1991 Oct - Who cited this? | PubMed ID: 1783990 | Fulltext

Induction of cytochrome P450IIE1 in the obese overfed rat.

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Raucy JL, Lasker JM, Kraner JC, Salazar DE, Lieber CS, and Corcoran GB

Molecular pharmacology 39(3):275-80, 1991 Mar - Who cited this? | PubMed ID: 2005876 | Fulltext

Obesity as a risk factor in drug-induced organ injury. III. Increased liver and kidney injury by furosemide in the obese overfed rat.

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Corcoran GB, Salazar DE, and Chan HH

Toxicology and applied pharmacology 98(1):12-24, 1989 Mar 15 - Who cited this? | PubMed ID: 2467406 | Fulltext

Obesity as a risk factor in drug-induced organ injury. IV. Increased gentamicin nephrotoxicity in the obese overfed rat.

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Corcoran GB and Salazar DE

The Journal of pharmacology and experimental therapeutics 248(1):17-22, 1989 Jan - Who cited this? | PubMed ID: 2913269 | Fulltext

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Papers authored by Salazar DE

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