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Papers authored by Ryffel B

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Histamine plays an essential regulatory role in lung inflammation and protective immunity in the acute phase of Mycobacterium tuberculosis infection.

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Carlos D, Fremond C, Samarina A, Vasseur V, Maillet I, Ramos SG, Erard F, Quesniaux V, Ohtsu H, Silva CL, Faccioli LH, and Ryffel B

Infection and immunity 77(12):5359-68, 2009 Dec - Who cited this? | PubMed ID: 19822651 | Fulltext

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors.

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Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, Vermaelen K, Panaretakis T, Mignot G, Ullrich E, Perfettini JL, Schlemmer F, Tasdemir E, Uhl M, Génin P, Civas A,

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Nature medicine 15(10):1170-8, 2009 Oct - Who cited this? | PubMed ID: 19767732 | Fulltext

Mycobacterial Phosphatidylinositol Mannosides Negatively Regulate Host Toll-like Receptor 4, MyD88-dependent Proinflammatory Cytokines, and TRIF-dependent Co-stimulatory Molecule Expression.

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Doz E, Rose S, Court N, Front S, Vasseur V, Charron S, Gilleron M, Puzo G, Fremaux I, Delneste Y, Erard F, Ryffel B, Martin OR, and Quesniaux VF

The Journal of biological chemistry 284(35):23187-96, 2009 Aug 28 - Who cited this? | PubMed ID: 19561082 | Fulltext

Lack of MyD88 protects the immunodeficient host against fatal lung inflammation triggered by the opportunistic bacteria Burkholderia cenocepacia.

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Ventura GM, Balloy V, Ramphal R, Khun H, Huerre M, Ryffel B, Plotkowski MC, Chignard M, and Si-Tahar M

Journal of immunology (Baltimore, Md. : 1950) 183(1):670-6, 2009 Jul 1 - Who cited this? | PubMed ID: 19535624 | Fulltext

IL-17 Receptor Signaling Is Required to Control Polymicrobial Sepsis.

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Freitas A, Alves-Filho JC, Victoni T, Secher T, Lemos HP, Sônego F, Cunha FQ, and Ryffel B

Journal of immunology (Baltimore, Md. : 1950) 182(12):7846-54, 2009 Jun 15 - Who cited this? | PubMed ID: 19494309 | Fulltext

Crucial Role of TNF Receptors 1 and 2 in the Control of Polymicrobial Sepsis.

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Secher T, Vasseur V, Poisson DM, Mitchell JA, Cunha FQ, Alves-Filho JC, and Ryffel B

Journal of immunology (Baltimore, Md. : 1950) 182(12):7855-64, 2009 Jun 15 - Who cited this? | PubMed ID: 19494310 | Fulltext

Toll-like receptor 2 is critical for induction of Reg3{beta} expression and intestinal clearance of Yersinia pseudotuberculosis.

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Dessein R, Gironella M, Vignal C, Peyrin-Biroulet L, Sokol H, Secher T, Lacas-Gervais S, Gratadoux JJ, Lafont F, Dagorn JC, Ryffel B, Akira S, Langella P, Nùñez G, Sirard JC, Iovanna J,

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Gut 58(6):771-6, 2009 Jun - Who cited this? | PubMed ID: 19174417 | Fulltext

Radioresistant cells expressing TLR5 control the respiratory epithelium's innate immune responses to flagellin.

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Janot L, Sirard JC, Secher T, Noulin N, Fick L, Akira S, Uematsu S, Didierlaurent A, Hussell T, Ryffel B, and Erard F

European journal of immunology 39(6):1587-96, 2009 Jun - Who cited this? | PubMed ID: 19424969 | Fulltext

iNOS-Producing Inflammatory Dendritic Cells Constitute the Major Infected Cell Type during the Chronic Leishmania major Infection Phase of C57BL/6 Resistant Mice.

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De Trez C, Magez S, Akira S, Ryffel B, Carlier Y, and Muraille E

PLoS pathogens 5(6):e1000494, 2009 Jun - Who cited this? | PubMed ID: 19557162 | Fulltext

Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis.

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Gasse P, Riteau N, Charron S, Girre S, Fick L, Pétrilli V, Tschopp J, Lagente V, Quesniaux VF, Ryffel B, and Couillin I

American journal of respiratory and critical care medicine 179(10):903-13, 2009 May 15 - Who cited this? | PubMed ID: 19218193 | Fulltext

Dominant-negative tumor necrosis factor protects from Mycobacterium bovis bacillus Calmette Guérin (BCG) and endotoxin-induced liver injury without compromising host immunity to BCG and Mycobacterium tuberculosis.

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Olleros ML, Vesin D, Lambou AF, Janssens JP, Ryffel B, Rose S, Frémond C, Quesniaux VF, Szymkowski DE, and Garcia I

The Journal of infectious diseases 199(7):1053-63, 2009 Apr 1 - Who cited this? | PubMed ID: 19222369 | Fulltext

Toll-like receptor 2 is essential for the sensing of oxidants during inflammation.

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Paul-Clark MJ, McMaster SK, Sorrentino R, Sriskandan S, Bailey LK, Moreno L, Ryffel B, Quesniaux VF, and Mitchell JA

American journal of respiratory and critical care medicine 179(4):299-306, 2009 Feb 15 - Who cited this? | PubMed ID: 19011150 | Fulltext

TLR2-dependent mast cell activation contributes to the control of Mycobacterium tuberculosis infection.

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Carlos D, Frantz FG, Souza-Júnior DA, Jamur MC, Oliver C, Ramos SG, Quesniaux VF, Ryffel B, Silva CL, Bozza MT, and Faccioli LH

Microbes and infection / Institut Pasteur 11(8-9):770-8, 2009 - Who cited this? | PubMed ID: 19442756 | Fulltext

Alternating electric fields (TTFields) inhibit metastatic spread of solid tumors to the lungs.

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Kirson ED, Giladi M, Gurvich Z, Itzhaki A, Mordechovich D, Schneiderman RS, Wasserman Y, Ryffel B, Goldsher D, and Palti Y

Clinical & experimental metastasis 26(7):633-40, 2009 - Who cited this? | PubMed ID: 19387848 | Fulltext

Dendritic cell and natural killer cell cross-talk: a pivotal role of CX3CL1 in NK cytoskeleton organization and activation.

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Pallandre JR, Krzewski K, Bedel R, Ryffel B, Caignard A, Rohrlich PS, Pivot X, Tiberghien P, Zitvogel L, Strominger JL, and Borg C

Blood 112(12):4420-4, 2008 Dec 1 - Who cited this? | PubMed ID: 18682600 | Fulltext

Toll like receptor - potential drug targets in infectious disease.

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Erard F and Ryffel B

Infectious disorders drug targets 8(4):221-31, 2008 Dec - Who cited this? | PubMed ID: 19075797 | Fulltext

Protective role of membrane tumour necrosis factor in the host's resistance to mycobacterial infection.

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Allie N, Alexopoulou L, Quesniaux VJ, Fick L, Kranidioti K, Kollias G, Ryffel B, and Jacobs M

Immunology 125(4):522-34, 2008 Dec - Who cited this? | PubMed ID: 18544042 | Fulltext

Interleukin-12p70 deficiency increases survival and diminishes pathology in Trypanosoma congolense infection.

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Barkhuizen M, Magez S, Ryffel B, and Brombacher F

The Journal of infectious diseases 198(9):1284-91, 2008 Nov 1 - Who cited this? | PubMed ID: 18816189 | Fulltext

[In Process Citation].

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Torres D, Dieudonne A, Vilain E, Ryffel B, Si Tahar M, and Gosset P

Revue des maladies respiratoires 25(9):1156, 2008 Nov - Who cited this? | PubMed ID: 19106923 | Fulltext

Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis.

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Gasse P, Riteau N, Pétrilli V, Tschopp J, Lagente V, Quesniaux VF, Ryffel B, and Couillin I

Revue des maladies respiratoires 25(9):1191, 2008 Nov - Who cited this? | PubMed ID: 19106986 | Fulltext

Effect of the dimethoate administration on a scrapie murine model.

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Hortells P, Monleón E, Acín C, Vargas A, Ryffel B, Cesbron JY, Badiola JJ, and Monzón M

Zoonoses and public health 55(7):368-75, 2008 Sep - Who cited this? | PubMed ID: 18667030 | Fulltext

Cutting edge: Priming of NK cells by IL-18.

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Chaix J, Tessmer MS, Hoebe K, Fuséri N, Ryffel B, Dalod M, Alexopoulou L, Beutler B, Brossay L, Vivier E, and Walzer T

Journal of immunology (Baltimore, Md. : 1950) 181(3):1627-31, 2008 Aug 1 - Who cited this? | PubMed ID: 18641298 | Fulltext

Toll-like receptor 4 agonists adsorbed to aluminium hydroxide adjuvant attenuate ovalbumin-specific allergic airway disease: role of MyD88 adaptor molecule and interleukin-12/interferon-gamma axis.

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Bortolatto J, Borducchi E, Rodriguez D, Keller AC, Faquim-Mauro E, Bortoluci KR, Mucida D, Gomes E, Christ A, Schnyder-Candrian S, Schnyder B, Ryffel B, and Russo M

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2008 Jun 25 - Who cited this? | PubMed ID: 18631348 | Fulltext

Trans-Presentation of IL-15 Dictates IFN-Producing Killer Dendritic Cells Effector Functions.

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Ullrich E, Bonmort M, Mignot G, Jacobs B, Bosisio D, Sozzani S, Jalil A, Louache F, Bulanova E, Geissman F, Ryffel B, Chaput N, Bulfone-Paus S, and Zitvogel L

Journal of immunology (Baltimore, Md. : 1950) 180(12):7887-97, 2008 Jun 15 - Who cited this? | PubMed ID: 18523252 | Fulltext

The Critical Role of IL-15 in the Antitumor Effects Mediated by the Combination Therapy Imatinib and IL-2.

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Mignot G, Ullrich E, Bonmort M, Ménard C, Apetoh L, Taieb J, Bosisio D, Sozzani S, Ferrantini M, Schmitz J, Mack M, Ryffel B, Bulfone-Paus S, Zitvogel L, and Chaput N

Journal of immunology (Baltimore, Md. : 1950) 180(10):6477-83, 2008 May 15 - Who cited this? | PubMed ID: 18453565 | Fulltext

CD14 Works with Toll-Like Receptor 2 to Contribute to Recognition and Control of Listeria monocytogenes Infection.

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Janot L, Secher T, Torres D, Maillet I, Pfeilschifter J, Quesniaux VF, Landmann R, Ryffel B, and Erard F

The Journal of infectious diseases, 2008 May 5 - Who cited this? | PubMed ID: 18462086 | Fulltext

Efficacy of membrane TNF mediated host resistance is dependent on mycobacterial virulence.

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Dambuza I, Allie N, Fick L, Johnston N, Fremond C, Mitchell J, Quesniaux VF, Ryffel B, and Jacobs M

Tuberculosis (Edinburgh, Scotland) 88(3):221, 2008 May - Who cited this? | PubMed ID: 17950671 | Fulltext

Toll-like receptor (TLR)2 and TLR3 synergy and cross-inhibition in murine myeloid dendritic cells.

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Vanhoutte F, Paget C, Breuilh L, Fontaine J, Vendeville C, Goriely S, Ryffel B, Faveeuw C, and Trottein F

Immunology letters 116(1):86-94, 2008 Feb 15 - Who cited this? | PubMed ID: 18166232 | Fulltext

Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-1R1/MyD88 Signaling Dependent.

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Doz E, Noulin N, Boichot E, Guénon I, Fick L, Le Bert M, Lagente V, Ryffel B, Schnyder B, Quesniaux VF, and Couillin I

Journal of immunology (Baltimore, Md. : 1950) 180(2):1169-78, 2008 Jan 15 - Who cited this? | PubMed ID: 18178857 | Fulltext

Trypanosomiasis-induced B cell apoptosis results in loss of protective anti-parasite antibody responses and abolishment of vaccine-induced memory responses.

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Radwanska M, Guirnalda P, De Trez C, Ryffel B, Black S, and Magez S

PLoS pathogens 4(5), 2008 - Who cited this? | PubMed ID: 18516300 | Fulltext

Both Functional LTbeta Receptor and TNF Receptor 2 Are Required for the Development of Experimental Cerebral Malaria.

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Togbe D, Loureiro de Sousa P, Fauconnier M, Boissay V, Fick L, Scheu S, Pfeffer K, Menard R, Grau GE, Doan BT, Beloeil JC, Renia L, Hansen AM, Ball HJ, Hunt NH, Ryffel B,

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PLoS ONE 3(7):e2608, 2008 - Who cited this? | PubMed ID: 18612394 | Fulltext

IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice.

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Gasse P, Mary C, Guenon I, Noulin N, Charron S, Schnyder-Candrian S, Schnyder B, Akira S, Quesniaux VF, Lagente V, Ryffel B, and Couillin I

The Journal of clinical investigation 117(12):3786, 2007 Dec - Who cited this? | PubMed ID: 17992263 | Fulltext

Role of pattern-recognition receptors in cardiovascular health and disease.

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Mitchell JA, Ryffel B, Quesniaux VF, Cartwright N, and Paul-Clark M

Biochemical Society transactions 35(Pt 6):1449, 2007 Dec - Who cited this? | PubMed ID: 18031243 | Fulltext

Toll-like receptor and tumour necrosis factor dependent endotoxin-induced acute lung injury.

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Togbe D, Schnyder-Candrian S, Schnyder B, Doz E, Noulin N, Janot L, Secher T, Gasse P, Lima C, Coelho FR, Vasseur V, Erard F, Ryffel B, Couillin I, and Moser R

International journal of experimental pathology 88(6):387-91, 2007 Dec - Who cited this? | PubMed ID: 18039275 | Fulltext

Control of allergic reactions in mice by an active anti-murine IL-4 immunization.

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Le Buanec H, Paturance S, Couillin I, Schnyder-Candrian S, Larcier P, Ryffel B, Bizzini B, Bensussan A, Burny A, Gallo R, Zagury D, and Peltre G

Vaccine 25(41):7206-16, 2007 Oct 10 - Who cited this? | PubMed ID: 17719148 | Fulltext

Activation of invariant NKT cells by toll-like receptor 9-stimulated dendritic cells requires type I interferon and charged glycosphingolipids.

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Paget C, Mallevaey T, Speak AO, Torres D, Fontaine J, Sheehan KC, Capron M, Ryffel B, Faveeuw C, Leite de Moraes M, Platt F, and Trottein F

Immunity 27(4):597-609, 2007 Oct - Who cited this? | PubMed ID: 17950005 | Fulltext

Tumor necrosis factor (TNF) receptor-1 (TNFp55) signal transduction and macrophage-derived soluble TNF are crucial for nitric oxide-mediated Trypanosoma congolense parasite killing.

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Magez S, Radwanska M, Drennan M, Fick L, Baral TN, Allie N, Jacobs M, Nedospasov S, Brombacher F, Ryffel B, and De Baetselier P

The Journal of infectious diseases 196(6):954, 2007 Sep 15 - Who cited this? | PubMed ID: 17703428 | Fulltext

Acylation determines the toll-like receptor (TLR)-dependent positive versus TLR2-, mannose receptor-, and SIGNR1-independent negative regulation of pro-inflammatory cytokines by mycobacterial lipomannan.

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Doz E, Rose S, Nigou J, Gilleron M, Puzo G, Erard F, Ryffel B, and Quesniaux VF

The Journal of biological chemistry 282(36):26014-25, 2007 Sep 7 - Who cited this? | PubMed ID: 17617634 | Fulltext

mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes.

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Mockey M, Bourseau E, Chandrashekhar V, Chaudhuri A, Lafosse S, Le Cam E, Quesniaux VF, Ryffel B, Pichon C, and Midoux P

Cancer gene therapy 14(9):802, 2007 Sep - Who cited this? | PubMed ID: 17589432 | Fulltext

Modeling the monosomy for the telomeric part of human chromosome 21 reveals haploinsufficient genes modulating the inflammatory and airway responses.

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Besson V, Brault V, Duchon A, Togbe D, Bizot JC, Quesniaux VF, Ryffel B, and Hérault Y

Human molecular genetics 16(17):2040-52, 2007 Sep 1 - Who cited this? | PubMed ID: 17591625 | Fulltext

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy.

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Apetoh L, Ghiringhelli F, Tesniere A, Obeid M, Ortiz C, Criollo A, Mignot G, Maiuri MC, Ullrich E, Saulnier P, Yang H, Amigorena S, Ryffel B, Barrat FJ, Saftig P, Levi F,

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Nature medicine 13(9):1050-9, 2007 Sep - Who cited this? | PubMed ID: 17704786 | Fulltext

Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection.

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Zalevsky J, Secher T, Ezhevsky SA, Janot L, Steed PM, O'Brien C, Eivazi A, Kung J, Nguyen DH, Doberstein SK, Erard F, Ryffel B, and Szymkowski DE

Journal of immunology (Baltimore, Md. : 1950) 179(3):1872-83, 2007 Aug 1 - Who cited this? | PubMed ID: 17641054 | Fulltext

IL-1 receptor-mediated signal is an essential component of MyD88-dependent innate response to Mycobacterium tuberculosis infection.

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Fremond CM, Togbe D, Doz E, Rose S, Vasseur V, Maillet I, Jacobs M, Ryffel B, and Quesniaux VF

Journal of immunology (Baltimore, Md. : 1950) 179(2):1178-89, 2007 Jul 15 - Who cited this? | PubMed ID: 17617611 | Fulltext

Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors.

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Kirson ED, Dbalý V, Tovarys F, Vymazal J, Soustiel JF, Itzhaki A, Mordechovich D, Steinberg-Shapira S, Gurvich Z, Schneiderman R, Wasserman Y, Salzberg M, Ryffel B, Goldsher D, Dekel E, and Palti Y

Proceedings of the National Academy of Sciences of the United States of America 104(24):10152-7, 2007 Jun 12 - Who cited this? | PubMed ID: 17551011 | Fulltext

Murine cerebral malaria development is independent of toll-like receptor signaling.

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Togbe D, Schofield L, Grau GE, Schnyder B, Boissay V, Charron S, Rose S, Beutler B, Quesniaux VF, and Ryffel B

The American journal of pathology 170(5):1640, 2007 May - Who cited this? | PubMed ID: 17456769 | Fulltext

Tumor necrosis factor is critical to control tuberculosis infection.

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Jacobs M, Togbe D, Fremond C, Samarina A, Allie N, Botha T, Carlos D, Parida SK, Grivennikov S, Nedospasov S, Monteiro A, Le Bert M, Quesniaux V, and Ryffel B

Microbes and infection / Institut Pasteur 9(5):623-8, 2007 Apr - Who cited this? | PubMed ID: 17409008 | Fulltext

Selective NOD1 agonists cause shock and organ injury/dysfunction in vivo.

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Cartwright N, Murch O, McMaster SK, Paul-Clark MJ, van Heel DA, Ryffel B, Quesniaux VF, Evans TW, Thiemermann C, and Mitchell JA

American journal of respiratory and critical care medicine 175(6):595, 2007 Mar 15 - Who cited this? | PubMed ID: 17234906 | Fulltext

Reactivation of tuberculosis by tumor necrosis factor neutralization.

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Jacobs M, Samarina A, Grivennikov S, Botha T, Allie N, Fremond C, Togbe D, Vasseur V, Rose S, Erard F, Monteiro A, Quesniaux V, and Ryffel B

European cytokine network 18(1):5-13, 2007 Mar - Who cited this? | PubMed ID: 17400533 | Fulltext

Natural killer cells prevent CD28-mediated Foxp3 transcription in CD4+CD25- T lymphocytes.

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Brillard E, Pallandre JR, Chalmers D, Ryffel B, Radlovic A, Seilles E, Rohrlich PS, Pivot X, Tiberghien P, Saas P, and Borg C

Experimental hematology 35(3):416-25, 2007 Mar - Who cited this? | PubMed ID: 17309822 | Fulltext

VEGF kinoid vaccine, a therapeutic approach against tumor angiogenesis and metastases.

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Rad FH, Le Buanec H, Paturance S, Larcier P, Genne P, Ryffel B, Bensussan A, Bizzini B, Gallo RC, Zagury D, and Uzan G

Proceedings of the National Academy of Sciences of the United States of America 104(8):2837, 2007 Feb 20 - Who cited this? | PubMed ID: 17301234 | Fulltext

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