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Papers authored by Ruvkun G

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C. elegans major fats are stored in vesicles distinct from lysosome-related organelles.

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O'Rourke EJ, Soukas AA, Carr CE, and Ruvkun G

Cell metabolism 10(5):430-5, 2009 Nov - Who cited this? | PubMed ID: 19883620 | Fulltext

A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants.

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Curran SP, Wu X, Riedel CG, and Ruvkun G

Nature 459(7250):1079-84, 2009 Jun 25 - Who cited this? | PubMed ID: 19506556 | Fulltext

Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans.

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Soukas AA, Kane EA, Carr CE, Melo JA, and Ruvkun G

Genes & development 23(4):496-511, 2009 Feb 15 - Who cited this? | PubMed ID: 19240135 | Fulltext

Biosynthesis of the Caenorhabditis elegans dauer pheromone.

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Butcher RA, Ragains JR, Li W, Ruvkun G, Clardy J, and Mak HY

Proceedings of the National Academy of Sciences of the United States of America 106(6):1875-9, 2009 Feb 10 - Who cited this? | PubMed ID: 19174521 | Fulltext

Fat metabolism links germline stem cells and longevity in C. elegans.

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Wang MC, O'Rourke EJ, and Ruvkun G

Science (New York, N.Y.) 322(5903):957-60, 2008 Nov 7 - Who cited this? | PubMed ID: 18988854 | Fulltext

The Most Conserved Genome Segments for Life Detection on Earth and Other Planets.

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Isenbarger TA, Carr CE, Johnson SS, Finney M, Church GM, Gilbert W, Zuber MT, and Ruvkun G

Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 2008 Oct 14 - Who cited this? | PubMed ID: 18853276 | Fulltext

The perfect storm of tiny RNAs.

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Ruvkun G

Nature medicine 14(10):1041-5, 2008 Oct - Who cited this? | PubMed ID: 18841145 | Fulltext

Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7.

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Fischer SE, Butler MD, Pan Q, and Ruvkun G

Nature, 2008 Sep 10 - Who cited this? | PubMed ID: 18784652 | Fulltext

Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development in Caenorhabditis elegans.

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Patel DS, Fang LL, Svy DK, Ruvkun G, and Li W

Development (Cambridge, England) 135(13):2239, 2008 Jul - Who cited this? | PubMed ID: 18495818 | Fulltext

Tiny RNA: Where do we come from? What are we? Where are we going?.

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Ruvkun G

Trends in plant science 13(7):313-6, 2008 Jul - Who cited this? | PubMed ID: 18562240 | Fulltext

The microRNA miR-1 regulates a MEF-2-dependent retrograde signal at neuromuscular junctions.

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Simon DJ, Madison JM, Conery AL, Thompson-Peer KL, Soskis M, Ruvkun GB, Kaplan JM, and Kim JK

Cell 133(5):903, 2008 May 30 - Who cited this? | PubMed ID: 18510933 | Fulltext

The exonuclease ERI-1 has a conserved dual role in 5.8S rRNA processing and RNAi.

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Gabel HW and Ruvkun G

Nature structural & molecular biology 15(5):531, 2008 May - Who cited this? | PubMed ID: 18438419 | Fulltext

Miniprimer PCR, a new lens for viewing the microbial world.

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Isenbarger TA, Finney M, Ríos-Velázquez C, Handelsman J, and Ruvkun G

Applied and environmental microbiology 74(3):840, 2008 Feb - Who cited this? | PubMed ID: 18083877 | Fulltext

MicroRNA-183 family conservation and ciliated neurosensory organ expression.

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Pierce ML, Weston MD, Fritzsch B, Gabel HW, Ruvkun G, and Soukup GA

Evolution & development 10(1):106 - Who cited this? | PubMed ID: 18184361 | Fulltext

A Whole-Genome RNAi Screen for C. elegans miRNA Pathway Genes.

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Parry DH, Xu J, and Ruvkun G

Current biology : CB 17(23):2013-22, 2007 Dec 4 - Who cited this? | PubMed ID: 18023351 | Fulltext

Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants.

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Samuelson AV, Carr CE, and Ruvkun G

Genes & development 21(22):2976-94, 2007 Nov 15 - Who cited this? | PubMed ID: 18006689 | Fulltext

Gravity force transduced by the MEC-4/MEC-10 DEG/ENaC channel modulates DAF-16/FoxO activity in Caenorhabditis elegans.

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Kim N, Dempsey CM, Kuan CJ, Zoval JV, O'Rourke E, Ruvkun G, Madou MJ, and Sze JY

Genetics 177(2):835, 2007 Oct - Who cited this? | PubMed ID: 17720915 | Fulltext

Lifespan regulation by evolutionarily conserved genes essential for viability.

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Curran SP and Ruvkun G

PLoS genetics 3(4), 2007 Apr 6 - Who cited this? | PubMed ID: 17411345 | Fulltext

Detection of broadly expressed neuronal genes in C. elegans.

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Ruvinsky I, Ohler U, Burge CB, and Ruvkun G

Developmental biology 302(2):617, 2007 Feb 15 - Who cited this? | PubMed ID: 17046742 | Fulltext

Identification of Caenorhabditis elegans genes regulating longevity using enhanced RNAi-sensitive strains.

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Samuelson AV, Klimczak RR, Thompson DB, Carr CE, and Ruvkun G

Cold Spring Harbor symposia on quantitative biology 72:489-97, 2007 - Who cited this? | PubMed ID: 18419309 | Fulltext

The mir-84 and let-7 paralogous microRNA genes of Caenorhabditis elegans direct the cessation of molting via the conserved nuclear hormone receptors NHR-23 and NHR-25.

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Hayes GD, Frand AR, and Ruvkun G

Development (Cambridge, England) 133(23):4631, 2006 Dec - Who cited this? | PubMed ID: 17065234 | Fulltext

Two membrane-associated tyrosine phosphatase homologs potentiate C. elegans AKT-1/PKB signaling.

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Hu PJ, Xu J, and Ruvkun G

PLoS genetics 2(7):e99, 2006 Jul - Who cited this? | PubMed ID: 16839187 | Fulltext

A genetic interaction between the vesicular acetylcholine transporter VAChT/UNC-17 and synaptobrevin/SNB-1 in C. elegans.

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Sandoval GM, Duerr JS, Hodgkin J, Rand JB, and Ruvkun G

Nature neuroscience 9(5):599-601, 2006 May - Who cited this? | PubMed ID: 16604067 | Fulltext

Polygenic control of Caenorhabditis elegans fat storage.

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Mak HY, Nelson LS, Basson M, Johnson CD, and Ruvkun G

Nature genetics 38(3):363-8, 2006 Mar - Who cited this? | PubMed ID: 16462744 | Fulltext

Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways.

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Duchaine TF, Wohlschlegel JA, Kennedy S, Bei Y, Conte D, Pang K, Brownell DR, Harding S, Mitani S, Ruvkun G, Yates JR, and Mello CC

Cell 124(2):343, 2006 Jan 27 - Who cited this? | PubMed ID: 16439208 | Fulltext

Clarifications on miRNA and cancer.

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Ruvkun G

Science (New York, N.Y.) 311(5757):36-7, 2006 Jan 6 - Who cited this? | PubMed ID: 16400132 | Fulltext

Misexpression of the Caenorhabditis elegans miRNA let-7 is sufficient to drive developmental programs.

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Hayes GD and Ruvkun G

Cold Spring Harbor symposia on quantitative biology 71:21-7, 2006 - Who cited this? | PubMed ID: 17381276 | Fulltext

Functional genomic analysis of C. elegans molting.

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Frand AR, Russel S, and Ruvkun G

PLoS biology 3(10):e312, 2005 Oct - Who cited this? | PubMed ID: 16122351 | Fulltext

Systematic analysis of genes required for synapse structure and function.

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Sieburth D, Ch'ng Q, Dybbs M, Tavazoie M, Kennedy S, Wang D, Dupuy D, Rual JF, Hill DE, Vidal M, Ruvkun G, and Kaplan JM

Nature 436(7050):510, 2005 Jul 28 - Who cited this? | PubMed ID: 16049479 | Fulltext

Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants.

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Wang D, Kennedy S, Conte D, Kim JK, Gabel HW, Kamath RS, Mello CC, and Ruvkun G

Nature 436(7050):593-7, 2005 Jul 28 - Who cited this? | PubMed ID: 16049496 | Fulltext

A systematic RNAi screen for longevity genes in C. elegans.

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Hamilton B, Dong Y, Shindo M, Liu W, Odell I, Ruvkun G, and Lee SS

Genes & development 19(13):1544-55, 2005 Jul 1 - Who cited this? | PubMed ID: 15998808 | Fulltext

Functional genomic analysis of RNA interference in C. elegans.

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Kim JK, Gabel HW, Kamath RS, Tewari M, Pasquinelli A, Rual JF, Kennedy S, Dybbs M, Bertin N, Kaplan JM, Vidal M, and Ruvkun G

Science (New York, N.Y.) 308(5725):1164-7, 2005 May 20 - Who cited this? | PubMed ID: 15790806 | Fulltext

Analysis of xbx genes in C. elegans.

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Efimenko E, Bubb K, Mak HY, Holzman T, Leroux MR, Ruvkun G, Thomas JH, and Swoboda P

Development (Cambridge, England) 132(8):1923-34, 2005 Apr - Who cited this? | PubMed ID: 15790967 | Fulltext

MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression.

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Mansfield JH, Harfe BD, Nissen R, Obenauer J, Srineel J, Chaudhuri A, Farzan-Kashani R, Zuker M, Pasquinelli AE, Ruvkun G, Sharp PA, Tabin CJ, and McManus MT

Nature genetics 36(10):1079-83, 2004 Oct - Who cited this? | PubMed ID: 15361871 | Fulltext

Intercellular signaling of reproductive development by the C. elegans DAF-9 cytochrome P450.

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Mak HY and Ruvkun G

Development (Cambridge, England) 131(8):1777-86, 2004 Apr - Who cited this? | PubMed ID: 15084462 | Fulltext

Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network.

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Tewari M, Hu PJ, Ahn JS, Ayivi-Guedehoussou N, Vidalain PO, Li S, Milstein S, Armstrong CM, Boxem M, Butler MD, Busiguina S, Rual JF, Ibarrola N, Chaklos ST, Bertin N, Vaglio P,

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Molecular cell 13(4):469, 2004 Feb 27 - Who cited this? | PubMed ID: 14992718 | Fulltext

A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans.

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Kennedy S, Wang D, and Ruvkun G

Nature 427(6975):645-9, 2004 Feb 12 - Who cited this? | PubMed ID: 14961122 | Fulltext

The 20 years it took to recognize the importance of tiny RNAs.

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Ruvkun G, Wightman B, and Ha I

Cell 116(2 Suppl):S93-6, 2 p following S96, 2004 Jan 23 - Who cited this? | PubMed ID: 15055593 | Fulltext

Identification of many microRNAs that copurify with polyribosomes in mammalian neurons.

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Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, and Ruvkun G

Proceedings of the National Academy of Sciences of the United States of America 101(1):360, 2004 Jan 6 - Who cited this? | PubMed ID: 14691248 | Fulltext

Regulation of Caenorhabditis elegans RNA interference by the daf-2 insulin stress and longevity signaling pathway.

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Wang D and Ruvkun G

Cold Spring Harbor symposia on quantitative biology 69:429-31, 2004 - Who cited this? | PubMed ID: 16117677 | Fulltext

Unraveling the secrets of the cell.

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Komaroff AL and Ruvkun G

Newsweek 142(23):96, 2003 Dec 8 - Who cited this? | PubMed ID: 14712576 | Fulltext

Functional tests of enhancer conservation between distantly related species.

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Ruvinsky I and Ruvkun G

Development (Cambridge, England) 130(21):5133, 2003 Nov - Who cited this? | PubMed ID: 12944426 | Fulltext

Activity of the Caenorhabditis elegans UNC-86 POU transcription factor modulates olfactory sensitivity.

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Sze JY and Ruvkun G

Proceedings of the National Academy of Sciences of the United States of America 100(16):9560-5, 2003 Aug 5 - Who cited this? | PubMed ID: 12883006 | Fulltext

The Caenorhabditis elegans ems class homeobox gene ceh-2 is required for M3 pharynx motoneuron function.

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Aspöck G, Ruvkun G, and Bürglin TR

Development (Cambridge, England) 130(15):3369-78, 2003 Aug - Who cited this? | PubMed ID: 12810585 | Fulltext

Coordinate regulation of small temporal RNAs at the onset of Drosophila metamorphosis.

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Bashirullah A, Pasquinelli AE, Kiger AA, Perrimon N, Ruvkun G, and Thummel CS

Developmental biology 259(1):1-8, 2003 Jul 1 - Who cited this? | PubMed ID: 12812783 | Fulltext

Expression of the 22 nucleotide let-7 heterochronic RNA throughout the Metazoa: a role in life history evolution?.

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Pasquinelli AE, McCoy A, Jiménez E, Saló E, Ruvkun G, Martindale MQ, and Baguñà J

Evolution & development 5(4):372 - Who cited this? | PubMed ID: 12823453 | Fulltext

Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens.

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Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, Calderwood SB, Ruvkun G, and Ausubel FM

Science (New York, N.Y.) 300(5627):1921, 2003 Jun 20 - Who cited this? | PubMed ID: 12817143 | Fulltext

Computational and experimental identification of C. elegans microRNAs.

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Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, and Kim J

Molecular cell 11(5):1253, 2003 May - Who cited this? | PubMed ID: 12769849 | Fulltext

DAF-16 target genes that control C. elegans life-span and metabolism.

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Lee SS, Kennedy S, Tolonen AC, and Ruvkun G

Science (New York, N.Y.) 300(5619):644-7, 2003 Apr 25 - Who cited this? | PubMed ID: 12690206 | Fulltext

daf-28 encodes a C. elegans insulin superfamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway.

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Li W, Kennedy SG, and Ruvkun G

Genes & development 17(7):844-58, 2003 Apr 1 - Who cited this? | PubMed ID: 12654727 | Fulltext

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Papers authored by Ruvkun G

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