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Papers authored by Rotter V

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The human 1-8D gene (IFITM2) is a novel p53 independent pro-apoptotic gene.

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Daniel-Carmi V, Makovitzki-Avraham E, Reuven EM, Goldstein I, Zilkha N, Rotter V, Tzehoval E, and Eisenbach L

International journal of cancer. Journal international du cancer 125(12):2810-9, 2009 Dec 15 - Who cited this? | PubMed ID: 19544527 | Fulltext

Mutations in the tetramerization domain of p53: More than just keeping monomers apart.

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Goldstein I and Rotter V

Cell cycle (Georgetown, Tex.) 8(20):3259-60, 2009 Oct 15 - Who cited this? | PubMed ID: 19823022 | Fulltext

When mutants gain new powers: news from the mutant p53 field.

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Brosh R and Rotter V

Nature reviews. Cancer 9(10):701-13, 2009 Oct - Who cited this? | PubMed ID: 19693097 | Fulltext

p53: balancing tumour suppression and implications for the clinic.

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Buganim Y and Rotter V

European journal of cancer (Oxford, England : 1990) 45 Suppl 1:217-34, 2009 Sep - Who cited this? | PubMed ID: 19775621 | Fulltext

Did experimental biology die? Lessons from 30 years of p53 research.

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Madar S, Goldstein I, and Rotter V

Cancer research 69(16):6378-80, 2009 Aug 15 - Who cited this? | PubMed ID: 19654301 | Fulltext

Differential influence of normal and cancer-associated fibroblasts on the growth of human epithelial cells in an in vitro cocultivation model of prostate cancer.

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Paland N, Kamer I, Kogan-Sakin I, Madar S, Goldfinger N, and Rotter V

Molecular cancer research : MCR 7(8):1212-23, 2009 Aug - Who cited this? | PubMed ID: 19671672 | Fulltext

Upregulation of survivin during immortalization of nontransformed human fibroblasts transduced with telomerase reverse transcriptase.

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Yuan J, Yang BM, Zhong ZH, Shats I, Milyavsky M, Rotter V, Lock RB, Reddel RR, and MacKenzie KL

Oncogene 28(29):2678-89, 2009 Jul 23 - Who cited this? | PubMed ID: 19483728 | Fulltext

Prostate stromal cells produce CXCL-1, CXCL-2, CXCL-3 and IL-8 in response to epithelia-secreted IL-1.

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Kogan-Sakin I, Cohen M, Paland N, Madar S, Solomon H, Molchadsky A, Brosh R, Buganim Y, Goldfinger N, Klocker H, Schalken JA, and Rotter V

Carcinogenesis 30(4):698-705, 2009 Apr - Who cited this? | PubMed ID: 19233959 | Fulltext

Cancer cells suppress p53 in adjacent fibroblasts.

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Bar J, Feniger-Barish R, Lukashchuk N, Shaham H, Moskovits N, Goldfinger N, Simansky D, Perlman M, Papa M, Yosepovich A, Rechavi G, Rotter V, and Oren M

Oncogene 28(6):933-6, 2009 Feb 12 - Who cited this? | PubMed ID: 19060923 | Fulltext

The expression of the DeltaNp73beta isoform of p73 leads to tetraploidy.

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Marrazzo E, Marchini S, Tavecchio M, Alberio T, Previdi S, Erba E, Rotter V, and Broggini M

European journal of cancer (Oxford, England : 1990) 45(3):443-53, 2009 Feb - Who cited this? | PubMed ID: 19008096 | Fulltext

Structural Basis of Restoring Sequence-Specific DNA Binding and Transactivation to Mutant p53 by Suppressor Mutations.

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Suad O, Rozenberg H, Brosh R, Diskin-Posner Y, Kessler N, Shimon LJ, Frolow F, Liran A, Rotter V, and Shakked Z

Journal of molecular biology 385(1):249-65, 2009 Jan 9 - Who cited this? | PubMed ID: 18996393 | Fulltext

Modulated expression of WFDC1 during carcinogenesis and cellular senescence.

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Madar S, Brosh R, Buganim Y, Ezra O, Goldstein I, Solomon H, Kogan I, Goldfinger N, Klocker H, and Rotter V

Carcinogenesis 30(1):20-7, 2009 Jan - Who cited this? | PubMed ID: 18842679 | Fulltext

Genome-wide profiling of histone h3 lysine 4 and lysine 27 trimethylation reveals an epigenetic signature in prostate carcinogenesis.

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Ke XS, Qu Y, Rostad K, Li WC, Lin B, Halvorsen OJ, Haukaas SA, Jonassen I, Petersen K, Goldfinger N, Rotter V, Akslen LA, Oyan AM, and Kalland KH

PLoS ONE 4(3):e4687, 2009 - Who cited this? | PubMed ID: 19262738 | Fulltext

Identification of gene networks associated with erythroid differentiation.

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Peller S, Tabach Y, Rotschild M, Garach-Joshua O, Cohen Y, Goldfinger N, and Rotter V

Blood cells, molecules & diseases 43(1):74-80, 2009 - Who cited this? | PubMed ID: 19329339 | Fulltext

p53 controls hPar1 function and expression.

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Salah Z, Haupt S, Maoz M, Baraz L, Rotter V, Peretz T, Haupt Y, and Bar-Shavit R

Oncogene, 2008 Sep 29 - Who cited this? | PubMed ID: 18820708 | Fulltext

Conditional RNA interference in vivo to study mutant p53 oncogenic gain of function on tumor malignancy.

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Bossi G, Marampon F, Maor-Aloni R, Zani B, Rotter V, Oren M, Strano S, Blandino G, and Sacchi A

Cell cycle (Georgetown, Tex.) 7(12), 2008 Apr 16 - Who cited this? | PubMed ID: 18594199 | Fulltext

Epithelial to Mesenchymal Transition of a Primary Prostate Cell Line with Switches of Cell Adhesion Modules but without Malignant Transformation.

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Ke XS, Qu Y, Goldfinger N, Rostad K, Hovland R, Akslen LA, Rotter V, Oyan AM, and Kalland KH

PLoS ONE 3(10):e3368, 2008 - Who cited this? | PubMed ID: 18852876 | Fulltext

p53 plays a role in mesenchymal differentiation programs, in a cell fate dependent manner.

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Molchadsky A, Shats I, Goldfinger N, Pevsner-Fischer M, Olson M, Rinon A, Tzahor E, Lozano G, Zipori D, Sarig R, and Rotter V

PLoS ONE 3(11):e3707, 2008 - Who cited this? | PubMed ID: 19002260 | Fulltext

p53-repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation.

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Brosh R, Shalgi R, Liran A, Landan G, Korotayev K, Nguyen GH, Enerly E, Johnsen H, Buganim Y, Solomon H, Goldstein I, Madar S, Goldfinger N, Børresen-Dale AL, Ginsberg D, Harris CC,

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Molecular systems biology 4:229, 2008 - Who cited this? | PubMed ID: 19034270 | Fulltext

Mutant p53 attenuates the SMAD-dependent transforming growth factor beta1 (TGF-beta1) signaling pathway by repressing the expression of TGF-beta receptor type II.

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Kalo E, Buganim Y, Shapira KE, Besserglick H, Goldfinger N, Weisz L, Stambolsky P, Henis YI, and Rotter V

Molecular and cellular biology 27(23):8228-42, 2007 Dec - Who cited this? | PubMed ID: 17875924 | Fulltext

Amyloid-beta precursor-like protein APLP1 is a novel p53 transcriptional target gene that augments neuroblastoma cell death upon genotoxic stress.

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Tang X, Milyavsky M, Goldfinger N, and Rotter V

Oncogene 26(52):7302-12, 2007 Nov 15 - Who cited this? | PubMed ID: 17533371 | Fulltext

Enhanced angiotensin II production by renal mesangium is responsible for apoptosis/proliferation of endothelial and epithelial cells in a model of malignant hypertension.

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Efrati S, Berman S, Goldfinger N, Erez N, Averbukh Z, Golik A, Rotter V, and Weissgarten J

Journal of hypertension 25(5):1041-52, 2007 May - Who cited this? | PubMed ID: 17414669 | Fulltext

Myocardin in tumor suppression and myofibroblast differentiation.

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Shats I, Milyavsky M, Cholostoy A, Brosh R, and Rotter V

Cell cycle (Georgetown, Tex.) 6(10):1141-6, 2007 May - Who cited this? | PubMed ID: 17495540 | Fulltext

Transcription regulation by mutant p53.

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Weisz L, Oren M, and Rotter V

Oncogene 26(15):2202-11, 2007 Apr 2 - Who cited this? | PubMed ID: 17401429 | Fulltext

Mutant p53 enhances nuclear factor kappaB activation by tumor necrosis factor alpha in cancer cells.

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Weisz L, Damalas A, Liontos M, Karakaidos P, Fontemaggi G, Maor-Aloni R, Kalis M, Levrero M, Strano S, Gorgoulis VG, Rotter V, Blandino G, and Oren M

Cancer research 67(6):2396, 2007 Mar 15 - Who cited this? | PubMed ID: 17363555 | Fulltext

Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect.

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Milyavsky M, Shats I, Cholostoy A, Brosh R, Buganim Y, Weisz L, Kogan I, Cohen M, Shatz M, Madar S, Kalo E, Goldfinger N, Yuan J, Ron S, MacKenzie K, Eden A,

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Cancer cell 11(2):133, 2007 Feb - Who cited this? | PubMed ID: 17292825 | Fulltext

Wide-scale analysis of human functional transcription factor binding reveals a strong bias towards the transcription start site.

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Tabach Y, Brosh R, Buganim Y, Reiner A, Zuk O, Yitzhaky A, Koudritsky M, Rotter V, and Domany E

PLoS ONE 2(8):e807, 2007 - Who cited this? | PubMed ID: 17726537 | Fulltext

Regulation of AIF expression by p53.

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Stambolsky P, Weisz L, Shats I, Klein Y, Goldfinger N, Oren M, and Rotter V

Cell death and differentiation 13(12):2140-9, 2006 Dec - Who cited this? | PubMed ID: 16729031 | Fulltext

Mutant p53 protects cells from 12-O-tetradecanoylphorbol-13-acetate-induced death by attenuating activating transcription factor 3 induction.

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Buganim Y, Kalo E, Brosh R, Besserglick H, Nachmany I, Rais Y, Stambolsky P, Tang X, Milyavsky M, Shats I, Kalis M, Goldfinger N, and Rotter V

Cancer research 66(22):10750-9, 2006 Nov 15 - Who cited this? | PubMed ID: 17108111 | Fulltext

Spotlight on...Varda Rotter. Interview by Tine Walma.

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Rotter V

FEBS letters 580(20):4763, 2006 Sep 4 - Who cited this? | PubMed ID: 16904673 | Fulltext

hTERT-immortalized prostate epithelial and stromal-derived cells: an authentic in vitro model for differentiation and carcinogenesis.

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Kogan I, Goldfinger N, Milyavsky M, Cohen M, Shats I, Dobler G, Klocker H, Wasylyk B, Voller M, Aalders T, Schalken JA, Oren M, and Rotter V

Cancer research 66(7):3531, 2006 Apr 1 - Who cited this? | PubMed ID: 16585177 | Fulltext

Repression of the MSP/MST-1 gene contributes to the antiapoptotic gain of function of mutant p53.

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Zalcenstein A, Weisz L, Stambolsky P, Bar J, Rotter V, and Oren M

Oncogene 25(3):359-69, 2006 Jan 19 - Who cited this? | PubMed ID: 16170349 | Fulltext

Single chain antibody against the common epitope of mutant p53 restores wild-type activity to mutant p53 protein.

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Orgad S, Goldfinger N, Cohen G, Rotter V, and Solomon B

FEBS letters 579(25):5609-15, 2005 Oct 24 - Who cited this? | PubMed ID: 16213502 | Fulltext

Transcriptional programs following genetic alterations in p53, INK4A, and H-Ras genes along defined stages of malignant transformation.

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Milyavsky M, Tabach Y, Shats I, Erez N, Cohen Y, Tang X, Kalis M, Kogan I, Buganim Y, Goldfinger N, Ginsberg D, Harris CC, Domany E, and Rotter V

Cancer research 65(11):4530-43, 2005 Jun 1 - Who cited this? | PubMed ID: 15930270 | Fulltext

The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation.

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Tabach Y, Milyavsky M, Shats I, Brosh R, Zuk O, Yitzhaky A, Mantovani R, Domany E, Rotter V, and Pilpel Y

Molecular systems biology 1:2005.0022, 2005 - Who cited this? | PubMed ID: 16729057 | Fulltext

p53-dependent down-regulation of telomerase is mediated by p21waf1.

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Shats I, Milyavsky M, Tang X, Stambolsky P, Erez N, Brosh R, Kogan I, Braunstein I, Tzukerman M, Ginsberg D, and Rotter V

The Journal of biological chemistry 279(49):50976-85, 2004 Dec 3 - Who cited this? | PubMed ID: 15371422 | Fulltext

Monoclonal antibody to a DNA-binding domain of p53 mimics charge structure of DNA: anti-idiotypes to the anti-p53 antibody are anti-DNA.

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Herkel J, Kam N, Erez N, Mimran A, Heifetz A, Eisenstein M, Rotter V, and Cohen IR

European journal of immunology 34(12):3623-32, 2004 Dec - Who cited this? | PubMed ID: 15495163 | Fulltext

Transactivation of the EGR1 gene contributes to mutant p53 gain of function.

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Weisz L, Zalcenstein A, Stambolsky P, Cohen Y, Goldfinger N, Oren M, and Rotter V

Cancer research 64(22):8318-27, 2004 Nov 15 - Who cited this? | PubMed ID: 15548700 | Fulltext

Activated p53 suppresses the histone methyltransferase EZH2 gene.

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Tang X, Milyavsky M, Shats I, Erez N, Goldfinger N, and Rotter V

Oncogene 23(34):5759-69, 2004 Jul 29 - Who cited this? | PubMed ID: 15208672 | Fulltext

Hypoxia-dependent regulation of PHD1: cloning and characterization of the human PHD1/EGLN2 gene promoter.

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Erez N, Stambolsky P, Shats I, Milyavsky M, Kachko T, and Rotter V

FEBS letters 567(2-3):311-5, 2004 Jun 4 - Who cited this? | PubMed ID: 15178343 | Fulltext

p53 is a regulator of macrophage differentiation.

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Matas D, Milyavsky M, Shats I, Nissim L, Goldfinger N, and Rotter V

Cell death and differentiation 11(4):458-67, 2004 Apr - Who cited this? | PubMed ID: 14713961 | Fulltext

DNA vaccination with CD25 protects rats from adjuvant arthritis and induces an antiergotypic response.

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Mimran A, Mor F, Carmi P, Quintana FJ, Rotter V, and Cohen IR

The Journal of clinical investigation 113(6):924-32, 2004 Mar - Who cited this? | PubMed ID: 15067325 | Fulltext

p53 mediates density-dependent growth arrest.

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Meerson A, Milyavsky M, and Rotter V

FEBS letters 559(1-3):152-8, 2004 Feb 13 - Who cited this? | PubMed ID: 14960324 | Fulltext

The role of p53 in base excision repair following genotoxic stress.

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Zurer I, Hofseth LJ, Cohen Y, Xu-Welliver M, Hussain SP, Harris CC, and Rotter V

Carcinogenesis 25(1):11-9, 2004 Jan - Who cited this? | PubMed ID: 14555612 | Fulltext

Material flow analysis of RDF-production processes.

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Rotter VS, Kost T, Winkler J, and Bilitewski B

Waste management (New York, N.Y.) 24(10):1005-21, 2004 - Who cited this? | PubMed ID: 15567666 | Fulltext

Expression of prolyl-hydroxylase-1 (PHD1/EGLN2) suppresses hypoxia inducible factor-1alpha activation and inhibits tumor growth.

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Erez N, Milyavsky M, Eilam R, Shats I, Goldfinger N, and Rotter V

Cancer research 63(24):8777-83, 2003 Dec 15 - Who cited this? | PubMed ID: 14695194 | Fulltext

The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation.

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Hofseth LJ, Khan MA, Ambrose M, Nikolayeva O, Xu-Welliver M, Kartalou M, Hussain SP, Roth RB, Zhou X, Mechanic LE, Zurer I, Rotter V, Samson LD, and Harris CC

The Journal of clinical investigation 112(12):1887-94, 2003 Dec - Who cited this? | PubMed ID: 14679184 | Fulltext

Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects.

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Rotter V, Nagaev I, and Smith U

The Journal of biological chemistry 278(46):45777-84, 2003 Nov 14 - Who cited this? | PubMed ID: 12952969 | Fulltext

Prolonged culture of telomerase-immortalized human fibroblasts leads to a premalignant phenotype.

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Milyavsky M, Shats I, Erez N, Tang X, Senderovich S, Meerson A, Tabach Y, Goldfinger N, Ginsberg D, Harris CC, and Rotter V

Cancer research 63(21):7147-57, 2003 Nov 1 - Who cited this? | PubMed ID: 14612508 | Fulltext

Mutant p53 gain of function: repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants.

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Zalcenstein A, Stambolsky P, Weisz L, Müller M, Wallach D, Goncharov TM, Krammer PH, Rotter V, and Oren M

Oncogene 22(36):5667, 2003 Aug 28 - Who cited this? | PubMed ID: 12944915 | Fulltext

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