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Papers authored by Rossjohn J

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T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire.

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Mallevaey T, Scott-Browne JP, Matsuda JL, Young MH, Pellicci DG, Patel O, Thakur M, Kjer-Nielsen L, Richardson SK, Cerundolo V, Howell AR, McCluskey J, Godfrey DI, Rossjohn J, Marrack P, and Gapin L

Immunity 31(1):60-71, 2009 Jul 17 - Who cited this? | PubMed ID: 19592274 | Fulltext

Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors.

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Pellicci DG, Patel O, Kjer-Nielsen L, Pang SS, Sullivan LC, Kyparissoudis K, Brooks AG, Reid HH, Gras S, Lucet IS, Koh R, Smyth MJ, Mallevaey T, Matsuda JL, Gapin L, McCluskey J,

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Immunity 31(1):47-59, 2009 Jul 17 - Who cited this? | PubMed ID: 19592275 | Fulltext

The Structure of the Bacterial Oxidoreductase Enzyme DsbA in Complex with a Peptide Reveals a Basis for Substrate Specificity in the Catalytic Cycle of DsbA Enzymes.

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Paxman JJ, Borg NA, Horne J, Thompson PE, Chin Y, Sharma P, Simpson JS, Wielens J, Piek S, Kahler CM, Sakellaris H, Pearce M, Bottomley SP, Rossjohn J, and Scanlon MJ

The Journal of biological chemistry 284(26):17835-45, 2009 Jun 26 - Who cited this? | PubMed ID: 19389711 | Fulltext

Antigen Ligation Triggers a Conformational Change within the Constant Domain of the alphabeta T Cell Receptor.

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Beddoe T, Chen Z, Clements CS, Ely LK, Bushell SR, Vivian JP, Kjer-Nielsen L, Pang SS, Dunstone MA, Liu YC, Macdonald WA, Perugini MA, Wilce MC, Burrows SR, Purcell AW, Tiganis T,

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Immunity 30(6):777-88, 2009 Jun 19 - Who cited this? | PubMed ID: 19464197 | Fulltext

The peptide length specificity of some HLA class I alleles is very broad and includes peptides of up to 25 amino acids in length.

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Bell MJ, Burrows JM, Brennan R, Miles JJ, Tellam J, McCluskey J, Rossjohn J, Khanna R, and Burrows SR

Molecular immunology 46(8-9):1911-7, 2009 May - Who cited this? | PubMed ID: 19157553 | Fulltext

Crystal structure of LipL32, the most abundant surface protein of pathogenic Leptospira spp.

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Vivian JP, Beddoe T, McAlister AD, Wilce MC, Zaker-Tabrizi L, Troy S, Byres E, Hoke DE, Cullen PA, Lo M, Murray GL, Adler B, and Rossjohn J

Journal of molecular biology 387(5):1229-38, 2009 Apr 17 - Who cited this? | PubMed ID: 19236879 | Fulltext

Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.

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Williams NK, Bamert RS, Patel O, Wang C, Walden PM, Wilks AF, Fantino E, Rossjohn J, and Lucet IS

Journal of molecular biology 387(1):219-32, 2009 Mar 20 - Who cited this? | PubMed ID: 19361440 | Fulltext

Phosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopes.

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Petersen J, Wurzbacher SJ, Williamson NA, Ramarathinam SH, Reid HH, Nair AK, Zhao AY, Nastovska R, Rudge G, Rossjohn J, and Purcell AW

Proceedings of the National Academy of Sciences of the United States of America 106(8):2776-81, 2009 Feb 24 - Who cited this? | PubMed ID: 19196958 | Fulltext

A long, naturally presented immunodominant epitope from NY-ESO-1 tumor antigen: implications for cancer vaccine design.

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Ebert LM, Liu YC, Clements CS, Robson NC, Jackson HM, Markby JL, Dimopoulos N, Tan BS, Luescher IF, Davis ID, Rossjohn J, Cebon J, Purcell AW, and Chen W

Cancer research 69(3):1046-54, 2009 Feb 1 - Who cited this? | PubMed ID: 19176376 | Fulltext

The shaping of T cell receptor recognition by self-tolerance.

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Gras S, Burrows SR, Kjer-Nielsen L, Clements CS, Liu YC, Sullivan LC, Bell MJ, Brooks AG, Purcell AW, McCluskey J, and Rossjohn J

Immunity 30(2):193-203, 2009 Feb - Who cited this? | PubMed ID: 19167249 | Fulltext

Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.

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Archbold JK, Macdonald WA, Gras S, Ely LK, Miles JJ, Bell MJ, Brennan RM, Beddoe T, Wilce MC, Clements CS, Purcell AW, McCluskey J, Burrows SR, and Rossjohn J

The Journal of experimental medicine 206(1):209-19, 2009 Jan 16 - Who cited this? | PubMed ID: 19139173 | Fulltext

Crystal Structures of the Lyn Protein Tyrosine Kinase Domain in Its Apo- and Inhibitor-bound State.

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Williams NK, Lucet IS, Klinken SP, Ingley E, and Rossjohn J

The Journal of biological chemistry 284(1):284-91, 2009 Jan 2 - Who cited this? | PubMed ID: 18984583 | Fulltext

Complete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchy.

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Kedzierska K, Guillonneau C, Gras S, Hatton LA, Webby R, Purcell AW, Rossjohn J, Doherty PC, and Turner SJ

Proceedings of the National Academy of Sciences of the United States of America, 2008 Dec 1 - Who cited this? | PubMed ID: 19047637 | Fulltext

The major histocompatibility complex class Ib molecule HLA-E at the interface between innate and adaptive immunity.

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Sullivan LC, Clements CS, Rossjohn J, and Brooks AG

Tissue antigens 72(5):415-24, 2008 Nov - Who cited this? | PubMed ID: 18946929 | Fulltext

Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin.

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Byres E, Paton AW, Paton JC, Löfling JC, Smith DF, Wilce MC, Talbot UM, Chong DC, Yu H, Huang S, Chen X, Varki NM, Varki A, Rossjohn J, and Beddoe T

Nature, 2008 Oct 29 - Who cited this? | PubMed ID: 18971931 | Fulltext

Prevention of cytotoxic T cell escape using a heteroclitic subdominant viral T cell determinant.

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Butler NS, Theodossis A, Webb AI, Nastovska R, Ramarathinam SH, Dunstone MA, Rossjohn J, Purcell AW, and Perlman S

PLoS pathogens 4(10):e1000186, 2008 Oct - Who cited this? | PubMed ID: 18949029 | Fulltext

Structural and biochemical characterisation of the oxidoreductase NmDsbA3 from Neisseria meningitidis.

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Vivian JP, Scoullar J, Robertson AL, Bottomley SP, Horne J, Chin Y, Wielens J, Thompson PE, Velkov T, Piek S, Byres E, Beddoe T, Wilce MC, Kahler C, Rossjohn J, and Scanlon MJ

The Journal of biological chemistry, 2008 Aug 20 - Who cited this? | PubMed ID: 18715864 | Fulltext

T-cells behaving badly: structural insights into alloreactivity and autoimmunity.

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Ely LK, Burrows SR, Purcell AW, Rossjohn J, and McCluskey J

Current opinion in immunology, 2008 Aug 1 - Who cited this? | PubMed ID: 18678247 | Fulltext

Crystal structure of an UDP-glucose specific glycosyltransferase from a mycobacterium species.

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Fulton Z, McAlister A, Wilce MC, Brammananth R, Zaker-Tabrizi L, Perugini MA, Bottomley SP, Coppel RL, Crellin PK, Rossjohn J, and Beddoe T

The Journal of biological chemistry, 2008 Jul 30 - Who cited this? | PubMed ID: 18667419 | Fulltext

Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity.

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Chessman D, Kostenko L, Lethborg T, Purcell AW, Williamson NA, Chen Z, Kjer-Nielsen L, Mifsud NA, Tait BD, Holdsworth R, Almeida CA, Nolan D, Macdonald WA, Archbold JK, Kellerher AD, Marriott D,

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Immunity 28(6):822-32, 2008 Jun - Who cited this? | PubMed ID: 18549801 | Fulltext

Enzymatic Properties of an Ecto-nucleoside Triphosphate Diphosphohydrolase from Legionella pneumophila: SUBSTRATE SPECIFICITY AND REQUIREMENT FOR VIRULENCE.

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Sansom FM, Riedmaier P, Newton HJ, Dunstone MA, Müller CE, Stephan H, Byres E, Beddoe T, Rossjohn J, Cowan PJ, d'Apice AJ, Robson SC, and Hartland EL

The Journal of biological chemistry 283(19):12909-18, 2008 May 9 - Who cited this? | PubMed ID: 18337253 | Fulltext

T-cell allorecognition: a case of mistaken identity or déjà vu?.

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Archbold JK, Macdonald WA, Burrows SR, Rossjohn J, and McCluskey J

Trends in immunology 29(5):220, 2008 May - Who cited this? | PubMed ID: 18378495 | Fulltext

Expression, purification, crystallization and preliminary X-ray characterization of a putative glycosyltransferase of the GT-A fold found in mycobacteria.

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Fulton Z, Crellin PK, Brammananth R, Zaker-Tabrizi L, Coppel RL, Rossjohn J, and Beddoe T

Acta crystallographica. Section F, Structural biology and crystallization communications 64(Pt 5):428-31, 2008 May 1 - Who cited this? | PubMed ID: 18453718 | Fulltext

Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection.

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Wynn KK, Fulton Z, Cooper L, Silins SL, Gras S, Archbold JK, Tynan FE, Miles JJ, McCluskey J, Burrows SR, Rossjohn J, and Khanna R

Blood 111(8):4283, 2008 Apr 15 - Who cited this? | PubMed ID: 18270323 | Fulltext

A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR.

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Wun KS, Borg NA, Kjer-Nielsen L, Beddoe T, Koh R, Richardson SK, Thakur M, Howell AR, Scott-Browne JP, Gapin L, Godfrey DI, McCluskey J, and Rossjohn J

The Journal of experimental medicine 205(4):939, 2008 Apr 14 - Who cited this? | PubMed ID: 18378792 | Fulltext

Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors.

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Hoare HL, Sullivan LC, Clements CS, Ely LK, Beddoe T, Henderson KN, Lin J, Reid HH, Brooks AG, and Rossjohn J

Journal of molecular biology 377(5):1297-303, 2008 Apr 11 - Who cited this? | PubMed ID: 18339401 | Fulltext

CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence.

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Petrie EJ, Clements CS, Lin J, Sullivan LC, Johnson D, Huyton T, Heroux A, Hoare HL, Beddoe T, Reid HH, Wilce MC, Brooks AG, and Rossjohn J

The Journal of experimental medicine 205(3):725-35, 2008 Mar 17 - Who cited this? | PubMed ID: 18332182 | Fulltext

Structural and Biological Basis of CTL Escape in Coronavirus-Infected Mice.

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Butler NS, Theodossis A, Webb AI, Dunstone MA, Nastovska R, Ramarathinam SH, Rossjohn J, Purcell AW, and Perlman S

Journal of immunology (Baltimore, Md. : 1950) 180(6):3926-37, 2008 Mar 15 - Who cited this? | PubMed ID: 18322201 | Fulltext

The fidelity, occasional promiscuity, and versatility of T cell receptor recognition.

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Godfrey DI, Rossjohn J, and McCluskey J

Immunity 28(3):304, 2008 Mar - Who cited this? | PubMed ID: 18342005 | Fulltext

Epitope-specific TCRbeta repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides.

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La Gruta NL, Thomas PG, Webb AI, Dunstone MA, Cukalac T, Doherty PC, Purcell AW, Rossjohn J, and Turner SJ

Proceedings of the National Academy of Sciences of the United States of America 105(6):2034, 2008 Feb 12 - Who cited this? | PubMed ID: 18238896 | Fulltext

T cell allorecognition and MHC restriction--A case of Jekyll and Hyde?.

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Archbold JK, Ely LK, Kjer-Nielsen L, Burrows SR, Rossjohn J, McCluskey J, and Macdonald WA

Molecular immunology 45(3):583, 2008 Feb - Who cited this? | PubMed ID: 17869342 | Fulltext

T-cell receptor bias and immunity.

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Gras S, Kjer-Nielsen L, Burrows SR, McCluskey J, and Rossjohn J

Current opinion in immunology 20(1):119-25, 2008 Feb - Who cited this? | PubMed ID: 18207719 | Fulltext

The production and crystallization of the human leukocyte antigen class II molecules HLA-DQ2 and HLA-DQ8 complexed with deamidated gliadin peptides implicated in coeliac disease.

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Henderson KN, Reid HH, Borg NA, Broughton SE, Huyton T, Anderson RP, McCluskey J, and Rossjohn J

Acta crystallographica. Section F, Structural biology and crystallization communications 63(Pt 12):1021-5, 2007 Dec 1 - Who cited this? | PubMed ID: 18084083 | Fulltext

The Heterodimeric Assembly of the CD94-NKG2 Receptor Family and Implications for Human Leukocyte Antigen-E Recognition.

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Sullivan LC, Clements CS, Beddoe T, Johnson D, Hoare HL, Lin J, Huyton T, Hopkins EJ, Reid HH, Wilce MC, Kabat J, Borrego F, Coligan JE, Rossjohn J, and Brooks AG

Immunity 27(6):900-11, 2007 Dec - Who cited this? | PubMed ID: 18083576 | Fulltext

Germline-encoded recognition of diverse glycolipids by natural killer T cells.

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Scott-Browne JP, Matsuda JL, Mallevaey T, White J, Borg NA, McCluskey J, Rossjohn J, Kappler J, Marrack P, and Gapin L

Nature immunology 8(10):1105-13, 2007 Oct - Who cited this? | PubMed ID: 17828267 | Fulltext

Beta-amino acid-containing hybrid peptides--new opportunities in peptidomimetics.

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Aguilar MI, Purcell AW, Devi R, Lew R, Rossjohn J, Smith AI, and Perlmutter P

Organic & biomolecular chemistry 5(18):2884-90, 2007 Sep 21 - Who cited this? | PubMed ID: 17728852 | Fulltext

A common fold mediates vertebrate defense and bacterial attack.

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Rosado CJ, Buckle AM, Law RH, Butcher RE, Kan WT, Bird CH, Ung K, Browne KA, Baran K, Bashtannyk-Puhalovich TA, Faux NG, Wong W, Porter CJ, Pike RN, Ellisdon AM, Pearce MC,

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Science (New York, N.Y.) 317(5844):1548-51, 2007 Sep 14 - Who cited this? | PubMed ID: 17717151 | Fulltext

CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor.

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Borg NA, Wun KS, Kjer-Nielsen L, Wilce MC, Pellicci DG, Koh R, Besra GS, Bharadwaj M, Godfrey DI, McCluskey J, and Rossjohn J

Nature 448(7149):44-9, 2007 Jul 5 - Who cited this? | PubMed ID: 17581592 | Fulltext

The N terminus of the serpin, tengpin, functions to trap the metastable native state.

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Zhang Q, Buckle AM, Law RH, Pearce MC, Cabrita LD, Lloyd GJ, Irving JA, Smith AI, Ruzyla K, Rossjohn J, Bottomley SP, and Whisstock JC

EMBO reports 8(7):658-63, 2007 Jul - Who cited this? | PubMed ID: 17557112 | Fulltext

A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease.

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Henderson KN, Tye-Din JA, Reid HH, Chen Z, Borg NA, Beissbarth T, Tatham A, Mannering SI, Purcell AW, Dudek NL, van Heel DA, McCluskey J, Rossjohn J, and Anderson RP

Immunity 27(1):23-34, 2007 Jul - Who cited this? | PubMed ID: 17629515 | Fulltext

A structural basis for the pH-dependent increase in fluorescence efficiency of chromoproteins.

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Battad JM, Wilmann PG, Olsen S, Byres E, Smith SC, Dove SG, Turcic KN, Devenish RJ, Rossjohn J, and Prescott M

Journal of molecular biology 368(4):998-1010, 2007 May 11 - Who cited this? | PubMed ID: 17376484 | Fulltext

More than one reason to rethink the use of peptides in vaccine design.

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Purcell AW, McCluskey J, and Rossjohn J

Nature reviews. Drug discovery 6(5):404-14, 2007 May - Who cited this? | PubMed ID: 17473845 | Fulltext

Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins.

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Rossjohn J, Polekhina G, Feil SC, Morton CJ, Tweten RK, and Parker MW

Journal of molecular biology 367(5):1227-36, 2007 Apr 13 - Who cited this? | PubMed ID: 17328912 | Fulltext

How a home-grown T cell receptor interacts with a foreign landscape.

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Rossjohn J and McCluskey J

Cell 129(1):19-20, 2007 Apr 6 - Who cited this? | PubMed ID: 17418777 | Fulltext

The impact of HLA-B micropolymorphism outside primary peptide anchor pockets on the CTL response to CMV.

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Burrows JM, Wynn KK, Tynan FE, Archbold J, Miles JJ, Bell MJ, Brennan RM, Walker S, McCluskey J, Rossjohn J, Khanna R, and Burrows SR

European journal of immunology 37(4):946-53, 2007 Apr - Who cited this? | PubMed ID: 17357107 | Fulltext

GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.

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Fenalti G, Law RH, Buckle AM, Langendorf C, Tuck K, Rosado CJ, Faux NG, Mahmood K, Hampe CS, Banga JP, Wilce M, Schmidberger J, Rossjohn J, El-Kabbani O, Pike RN, Smith AI,

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Nature structural & molecular biology 14(4):280-6, 2007 Apr - Who cited this? | PubMed ID: 17384644 | Fulltext

Structural studies on HLA-G: implications for ligand and receptor binding.

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Clements CS, Kjer-Nielsen L, McCluskey J, and Rossjohn J

Human immunology 68(4):220-6, 2007 Apr - Who cited this? | PubMed ID: 17400055 | Fulltext

The 2.7 A crystal structure of the autoinhibited human c-Fms kinase domain.

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Walter M, Lucet IS, Patel O, Broughton SE, Bamert R, Williams NK, Fantino E, Wilks AF, and Rossjohn J

Journal of molecular biology 367(3):839, 2007 Mar 30 - Who cited this? | PubMed ID: 17292918 | Fulltext

A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule.

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Tynan FE, Reid HH, Kjer-Nielsen L, Miles JJ, Wilce MC, Kostenko L, Borg NA, Williamson NA, Beddoe T, Purcell AW, Burrows SR, McCluskey J, and Rossjohn J

Nature immunology 8(3):268-76, 2007 Mar - Who cited this? | PubMed ID: 17259989 | Fulltext

The 1.6 A crystal structure of the catalytic domain of PlyB, a bacteriophage lysin active against Bacillus anthracis.

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Porter CJ, Schuch R, Pelzek AJ, Buckle AM, McGowan S, Wilce MC, Rossjohn J, Russell R, Nelson D, Fischetti VA, and Whisstock JC

Journal of molecular biology 366(2):540-50, 2007 Feb 16 - Who cited this? | PubMed ID: 17182056 | Fulltext

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