Papers authored by Roitelman J

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SPFH1 and SPFH2 mediate the ubiquitination and degradation of inositol 1,4,5-trisphosphate receptors in muscarinic receptor-expressing HeLa cells.
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Wang Y, Pearce MM, Sliter DA, Olzmann JA, Christianson JC, Kopito RR, Boeckmann S, Gagen C, Leichner GS, Roitelman J, and Wojcikiewicz RJ
Biochimica et biophysica acta 1793(11):1710-8, 2009 Nov - Who cited this? | PubMed ID: 19751772 | Fulltext
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Dislocation of HMG-CoA reductase and Insig-1, two polytopic endoplasmic reticulum proteins, en route to proteasomal degradation.
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Leichner GS, Avner R, Harats D, and Roitelman J
Molecular biology of the cell 20(14):3330-41, 2009 Jul - Who cited this? | PubMed ID: 19458199 | Fulltext
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Specific induction of tumor neovasculature death by modified murine PPE-1 promoter armed with HSV-TK.
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Varda-Bloom N, Hodish I, Shaish A, Greenberger S, Tal R, Feder B, Roitelman J, Breitbart E, Bangio L, Barshack I, Pfeffer R, and Harats D
Pathobiology : journal of immunopathology, molecular and cellular biology 75(6):346-55, 2008 - Who cited this? | PubMed ID: 19096230 | Fulltext
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The low-density lipoprotein receptor plays a role in the infection of primary human hepatocytes by hepatitis C virus.
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Molina S, Castet V, Fournier-Wirth C, Pichard-Garcia L, Avner R, Harats D, Roitelman J, Barbaras R, Graber P, Ghersa P, Smolarsky M, Funaro A, Malavasi F, Larrey D, Coste J, Fabre JM, 
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Journal of hepatology 46(3):411-9, 2007 Mar - Who cited this? | PubMed ID: 17156886 | Fulltext
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Ubiquitin is conjugated by membrane ubiquitin ligase to three sites, including the N terminus, in transmembrane region of mammalian 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for sterol-regulated enzyme degradation.
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Doolman R, Leichner GS, Avner R, and Roitelman J
The Journal of biological chemistry 279(37):38184-93, 2004 Sep 10 - Who cited this? | PubMed ID: 15247208 | Fulltext
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Apomine, a novel hypocholesterolemic agent, accelerates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and stimulates low density lipoprotein receptor activity.
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Roitelman J, Masson D, Avner R, Ammon-Zufferey C, Perez A, Guyon-Gellin Y, Bentzen CL, and Niesor EJ
The Journal of biological chemistry 279(8):6465-73, 2004 Feb 20 - Who cited this? | PubMed ID: 14627708 | Fulltext
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Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum.
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Kikkert M, Doolman R, Dai M, Avner R, Hassink G, van Voorden S, Thanedar S, Roitelman J, Chau V, and Wiertz E
The Journal of biological chemistry 279(5):3525-34, 2004 Jan 30 - Who cited this? | PubMed ID: 14593114 | Fulltext
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Lovastatin and phospholipase Cgamma regulate constitutive and protein kinase C dependent integrin mediated interactions of human T-cells with collagen.
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Bank I, Koltakov A, Nir-Glickman E, Goldstein I, Li J, Roitelman J, and Chess L
Cellular immunology 223(1):35-45, 2003 May - Who cited this? | PubMed ID: 12914756 | Fulltext
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Interindividual variability in sensitivity to warfarin--Nature or nurture?.
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Loebstein R, Yonath H, Peleg D, Almog S, Rotenberg M, Lubetsky A, Roitelman J, Harats D, Halkin H, and Ezra D
Clinical pharmacology and therapeutics 70(2):159-64, 2001 Aug - Who cited this? | PubMed ID: 11503010 | Fulltext
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The ubiquitin-proteasome pathway mediates the regulated degradation of mammalian 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
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Ravid T, Doolman R, Avner R, Harats D, and Roitelman J
The Journal of biological chemistry 275(46):35840-7, 2000 Nov 17 - Who cited this? | PubMed ID: 10964918 | Fulltext
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Impaired regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation in lovastatin-resistant cells.
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Ravid T, Avner R, Polak-Charcon S, Faust JR, and Roitelman J
The Journal of biological chemistry 274(41):29341-51, 1999 Oct 8 - Who cited this? | PubMed ID: 10506194 | Fulltext
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Improved PCR amplification/Hhal restriction for unambiguous determination of apolipoprotein E alleles.
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Appel E, Eisenberg S, and Roitelman J
Clinical chemistry 41(2):187-90, 1995 Feb - Who cited this? | PubMed ID: 7874769 | Fulltext
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Direct plasma radioimmunoassay for rat amylin-(1-37): concentrations with acquired and genetic obesity.
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Pieber TR, Roitelman J, Lee Y, Luskey KL, and Stein DT
The American journal of physiology 267(1 Pt 1):E156-64, 1994 Jul - Who cited this? | PubMed ID: 8048505 | Fulltext
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Lack of correlation between 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and lovastatin resistance in nerve growth factor treated PC-12 cells.
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Marom M, Ben-Baruch G, Roitelman J, and Kloog Y
Cellular and molecular neurobiology 14(2):119-32, 1994 Apr - Who cited this? | PubMed ID: 7842472 | Fulltext
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In vivo inhibition of cyclin B degradation and induction of cell-cycle arrest in mammalian cells by the neutral cysteine protease inhibitor N-acetylleucylleucylnorleucinal.
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Sherwood SW, Kung AL, Roitelman J, Simoni RD, and Schimke RT
Proceedings of the National Academy of Sciences of the United States of America 90(8):3353-7, 1993 Apr 15 - Who cited this? | PubMed ID: 8386372 | Fulltext
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Distinct sterol and nonsterol signals for the regulated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase.
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Roitelman J and Simoni RD
The Journal of biological chemistry 267(35):25264-73, 1992 Dec 15 - Who cited this? | PubMed ID: 1460026 | Fulltext
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Immunological evidence for eight spans in the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for enzyme degradation in the endoplasmic reticulum.
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Roitelman J, Olender EH, Bar-Nun S, Dunn WA, and Simoni RD
The Journal of cell biology 117(5):959-73, 1992 Jun - Who cited this? | PubMed ID: 1374417 | Fulltext
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Peptide transport by the multidrug resistance pump.
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Sharma RC, Inoue S, Roitelman J, Schimke RT, and Simoni RD
The Journal of biological chemistry 267(9):5731-4, 1992 Mar 25 - Who cited this? | PubMed ID: 1348245 | Fulltext
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Involvement of calcium in the mevalonate-accelerated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase.
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Roitelman J, Bar-Nun S, Inoue S, and Simoni RD
The Journal of biological chemistry 266(24):16085-91, 1991 Aug 25 - Who cited this? | PubMed ID: 1908464 | Fulltext
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Inhibition of degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in vivo by cysteine protease inhibitors.
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Inoue S, Bar-Nun S, Roitelman J, and Simoni RD
The Journal of biological chemistry 266(20):13311-7, 1991 Jul 15 - Who cited this? | PubMed ID: 1906466 | Fulltext
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Studies on the catalytic site of rat liver HMG-CoA reductase: interaction with CoA-thioesters and inactivation by iodoacetamide.
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Roitelman J and Shechter I
Journal of lipid research 30(1):97-107, 1989 Jan - Who cited this? | PubMed ID: 2918254 | Fulltext
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Allosteric and non-allosteric forms of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase: differential inhibition of activity by adenosine 2'-monophospho-5'-diphosphoribose.
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Roitelman J and Shechter I
Journal of lipid research 27(8):828-35, 1986 Aug - Who cited this? | PubMed ID: 3772249 | Fulltext
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Altered kinetic properties of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase following dietary manipulations.
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Roitelman J and Shechter I
The Journal of biological chemistry 261(11):5061-6, 1986 Apr 15 - Who cited this? | PubMed ID: 3514608 | Fulltext
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Structural requirements for allosteric activators of rat liver microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase.
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Roitelman J and Shechter I
Biochemical and biophysical research communications 125(3):902-7, 1984 Dec 28 - Who cited this? | PubMed ID: 6517944 | Fulltext
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Allosteric activation of rat liver microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase by nicotinamide adenine dinucleotides.
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Roitelman J and Shechter I
The Journal of biological chemistry 259(22):14029-32, 1984 Nov 25 - Who cited this? | PubMed ID: 6501287 | Fulltext
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Regulation of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase. Evidence for thiol-dependent allosteric modulation of enzyme activity.
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Roitelman J and Shechter I
The Journal of biological chemistry 259(2):870-7, 1984 Jan 25 - Who cited this? | PubMed ID: 6693400 | Fulltext
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Photoactivated aflatoxins are mutagens to Salmonella typhimurium and bind covalently to DNA in vitro.
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Israel-Kalinsky H, Tuch J, Roitelman J, and Stark AA
Carcinogenesis 3(4):423-9, 1982 - Who cited this? | PubMed ID: 7046977 | Fulltext
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