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Papers authored by Robertson JG

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Aglycone exploration of C-arylglucoside inhibitors of renal sodium-dependent glucose transporter SGLT2.

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Ellsworth BA, Meng W, Patel M, Girotra RN, Wu G, Sher PM, Hagan DL, Obermeier MT, Humphreys WG, Robertson JG, Wang A, Han S, Waldron TL, Morgan NN, Whaley JM, and Washburn WN

Bioorganic & medicinal chemistry letters 18(17):4770-3, 2008 Sep 1 - Who cited this? | PubMed ID: 18707880 | Fulltext

Discovery of Dapagliflozin: A Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes.

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Meng W, Ellsworth BA, Nirschl AA, McCann PJ, Patel M, Girotra RN, Wu G, Sher PM, Morrison EP, Biller SA, Zahler R, Deshpande PP, Pullockaran A, Hagan DL, Morgan N, Taylor JR,

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Journal of medicinal chemistry 51(5):1145-9, 2008 Mar 13 - Who cited this? | PubMed ID: 18260618 | Fulltext

Potent non-nitrile dipeptidic dipeptidyl peptidase IV inhibitors.

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Simpkins LM, Bolton S, Pi Z, Sutton JC, Kwon C, Zhao G, Magnin DR, Augeri DJ, Gungor T, Rotella DP, Sun Z, Liu Y, Slusarchyk WS, Marcinkeviciene J, Robertson JG, Wang A,

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Bioorganic & medicinal chemistry letters 17(23):6476-80, 2007 Dec 1 - Who cited this? | PubMed ID: 17937986 | Fulltext

Enzymes as a special class of therapeutic target: clinical drugs and modes of action.

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Robertson JG

Current opinion in structural biology 17(6):674-9, 2007 Dec - Who cited this? | PubMed ID: 17884461 | Fulltext

Seco-prolinenitrile inhibitors of dipeptidyl peptidase IV define minimal pharmacophore requirements at P1.

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Magnin DR, Taunk PC, Robertson JG, Wang A, Marcinkeviciene J, Kirby MS, and Hamann LG

Bioorganic & medicinal chemistry letters 16(6):1731-4, 2006 Mar 15 - Who cited this? | PubMed ID: 16376077 | Fulltext

Diprolyl nitriles as potent dipeptidyl peptidase IV inhibitors.

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Zhao G, Taunk PC, Magnin DR, Simpkins LM, Robl JA, Wang A, Robertson JG, Marcinkeviciene J, Sitkoff DF, Parker RA, Kirby MS, and Hamann LG

Bioorganic & medicinal chemistry letters 15(18):3992-5, 2005 Sep 15 - Who cited this? | PubMed ID: 16046120 | Fulltext

Discovery and preclinical profile of Saxagliptin (BMS-477118): a highly potent, long-acting, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.

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Augeri DJ, Robl JA, Betebenner DA, Magnin DR, Khanna A, Robertson JG, Wang A, Simpkins LM, Taunk P, Huang Q, Han SP, Abboa-Offei B, Cap M, Xin L, Tao L, Tozzo E,

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Journal of medicinal chemistry 48(15):5025-37, 2005 Jul 28 - Who cited this? | PubMed ID: 16033281 | Fulltext

Mechanistic basis of enzyme-targeted drugs.

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Robertson JG

Biochemistry 44(15):5561-71, 2005 Apr 19 - Who cited this? | PubMed ID: 15823014 | Fulltext

Synthesis of novel potent dipeptidyl peptidase IV inhibitors with enhanced chemical stability: interplay between the N-terminal amino acid alkyl side chain and the cyclopropyl group of alpha-aminoacyl-l-cis-4,5-methanoprolinenitrile-based inhibitors.

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Magnin DR, Robl JA, Sulsky RB, Augeri DJ, Huang Y, Simpkins LM, Taunk PC, Betebenner DA, Robertson JG, Abboa-Offei BE, Wang A, Cap M, Xin L, Tao L, Sitkoff DF, Malley MF,

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Journal of medicinal chemistry 47(10):2587-98, 2004 May 6 - Who cited this? | PubMed ID: 15115400 | Fulltext

Application of robotics to steady state enzyme kinetics: analysis of tight-binding inhibitors of dipeptidyl peptidase IV.

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Wang A, Huang Y, Taunk P, Magnin DR, Ghosh K, and Robertson JG

Analytical biochemistry 321(2):157-66, 2003 Oct 15 - Who cited this? | PubMed ID: 14511679 | Fulltext

Hepatocyte growth factor and macrophage-stimulating protein are upregulated during excisional wound repair in rats.

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Cowin AJ, Kallincos N, Hatzirodos N, Robertson JG, Pickering KJ, Couper J, and Belford DA

Cell and tissue research 306(2):239-50, 2001 Nov - Who cited this? | PubMed ID: 11702235 | Fulltext

Mitogenic whey extract stimulates wound repair activity in vitro and promotes healing of rat incisional wounds.

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Rayner TE, Cowin AJ, Robertson JG, Cooter RD, Harries RC, Regester GO, Smithers GW, Goddard C, and Belford DA

American journal of physiology. Regulatory, integrative and comparative physiology 278(6):R1651-60, 2000 Jun - Who cited this? | PubMed ID: 10848535 | Fulltext

4-Thiazolidinones: novel inhibitors of the bacterial enzyme MurB.

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Andres CJ, Bronson JJ, D'Andrea SV, Deshpande MS, Falk PJ, Grant-Young KA, Harte WE, Ho HT, Misco PF, Robertson JG, Stock D, Sun Y, and Walsh AW

Bioorganic & medicinal chemistry letters 10(8):715-7, 2000 Apr 17 - Who cited this? | PubMed ID: 10782671 | Fulltext

Clearance of IGFs and insulin from wounds: effect of IGF-binding protein interactions.

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Robertson JG, Belford DA, and Ballard FJ

The American journal of physiology 276(4 Pt 1):E663-71, 1999 Apr - Who cited this? | PubMed ID: 10198302 | Fulltext

Characterization of NADP+ binding to perdeuterated MurB: backbone atom NMR assignments and chemical-shift changes.

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Constantine KL, Mueller L, Goldfarb V, Wittekind M, Metzler WJ, Yanchunas J, Robertson JG, Malley MF, Friedrichs MS, and Farmer BT

Journal of molecular biology 267(5):1223-46, 1997 Apr 18 - Who cited this? | PubMed ID: 9150408 | Fulltext

Spectroscopic properties of Escherichia coli UDP-N-acetylenolpyruvylglucosamine reductase.

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Axley MJ, Fairman R, Yanchunas J, Villafranca JJ, and Robertson JG

Biochemistry 36(4):812-22, 1997 Jan 28 - Who cited this? | PubMed ID: 9020779 | Fulltext

Growth hormone but not insulin-like growth factor-I improves wound strength in pigs.

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Robertson JG, Walton PE, Dunshea F, Dunaiski V, and Ballard FJ

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 5(2):168-74, 1997 - Who cited this? | PubMed ID: 16984427 | Fulltext

Localizing the NADP+ binding site on the MurB enzyme by NMR.

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Farmer BT, Constantine KL, Goldfarb V, Friedrichs MS, Wittekind M, Yanchunas J, Robertson JG, and Mueller L

Nature structural biology 3(12):995-7, 1996 Dec - Who cited this? | PubMed ID: 8946851 | Fulltext

Insulin-like growth factor I (IGF-I) and IGF-Binding proteins in rat wound fluid.

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Robertson JG, Pickering KJ, and Belford DA

Endocrinology 137(7):2774-81, 1996 Jul - Who cited this? | PubMed ID: 8770897 | Fulltext

Crystallization and preliminary crystallographic analysis of E. coli uridine 5'-diphospho-N-acetylenolpyruvylglucosamine reductase in two new crystal forms.

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Ohringer SL, Chang CY, Sheriff S, Klei HE, Sack JS, Jacobson BL, Yanchunas J, Lavoie T, Dhalla AM, Robertson JG, and Einspahr HM

Acta crystallographica. Section D, Biological crystallography 52(Pt 3):586-8, 1996 May 1 - Who cited this? | PubMed ID: 15299687 | Fulltext

Structural studies of Escherichia coli UDP-N-acetylmuramate:L-alanine ligase.

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Jin H, Emanuele JJ, Fairman R, Robertson JG, Hail ME, Ho HT, Falk PJ, and Villafranca JJ

Biochemistry 35(5):1423-31, 1996 Feb 6 - Who cited this? | PubMed ID: 8634272 | Fulltext

Determination of subunit dissociation constants in native and inactivated CTP synthetase by sedimentation equilibrium.

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Robertson JG

Biochemistry 34(22):7533-41, 1995 Jun 6 - Who cited this? | PubMed ID: 7779798 | Fulltext

Steady-state kinetic mechanism of Escherichia coli UDP-N-acetylenolpyruvylglucosamine reductase.

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Dhalla AM, Yanchunas J, Ho HT, Falk PJ, Villafranca JJ, and Robertson JG

Biochemistry 34(16):5390-402, 1995 Apr 25 - Who cited this? | PubMed ID: 7727397 | Fulltext

Dimerization of native and C-terminally proteolyzed p56lck tyrosine kinase.

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Robertson JG, Yanchunas J, and Villafranca JJ

Archives of biochemistry and biophysics 317(1):259-66, 1995 Feb 20 - Who cited this? | PubMed ID: 7872793 | Fulltext

Complete assignment of disulfide bonds in bovine dopamine beta-hydroxylase.

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Robertson JG, Adams GW, Medzihradszky KF, Burlingame AL, and Villafranca JJ

Biochemistry 33(38):11563-75, 1994 Sep 27 - Who cited this? | PubMed ID: 7918370 | Fulltext

Child support orders: a perspective on reform.

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Garfinkel I, Melli MS, and Robertson JG

The Future of children / Center for the Future of Children, the David and Lucile Packard Foundation 4(1):84-100, 1994 - Who cited this? | PubMed ID: 7922287 | Fulltext

Characterization of metal ion activation and inhibition of CTP synthetase.

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Robertson JG and Villafranca JJ

Biochemistry 32(14):3769-77, 1993 Apr 13 - Who cited this? | PubMed ID: 8385490 | Fulltext

Regulation of the pyruvate dehydrogenase multienzyme complex.

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Behal RH, Buxton DB, Robertson JG, and Olson MS

Annual review of nutrition 13:497-520, 1993 - Who cited this? | PubMed ID: 8369156 | Fulltext

Inactivation and covalent modification of CTP synthetase by thiourea dioxide.

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Robertson JG, Sparvero LJ, and Villafranca JJ

Protein science : a publication of the Protein Society 1(10):1298-307, 1992 Oct - Who cited this? | PubMed ID: 1303749 | Fulltext

The effect of modification on the susceptibility of collagen to proteolysis: I. Chemical modification of amino acid side chains.

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Diamond AM, Gorham SD, Etherington DJ, Robertson JG, and Light ND

Matrix (Stuttgart, Germany) 11(5):321-9, 1991 Nov - Who cited this? | PubMed ID: 1811163 | Fulltext

Bovine heart pyruvate dehydrogenase kinase stimulation by alpha-ketoisovalerate.

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Robertson JG, Barron LL, and Olson MS

The Journal of biological chemistry 265(28):16814-20, 1990 Oct 5 - Who cited this? | PubMed ID: 2211597 | Fulltext

Primary amino acid sequence of bovine dopamine beta-hydroxylase.

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Robertson JG, Desai PR, Kumar A, Farrington GK, Fitzpatrick PF, and Villafranca JJ

The Journal of biological chemistry 265(2):1029-35, 1990 Jan 15 - Who cited this? | PubMed ID: 2295597 | Fulltext

Integrated radiologic information system: a radiology multimedia communication system.

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Hickey NM, Robertson JG, and Coristine M

Journal of thoracic imaging 5(1):77-84, 1990 Jan - Who cited this? | PubMed ID: 2299706 | Fulltext

DSIR biotechnology.

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Robertson JG

Australian journal of biotechnology 4(1):10-2, 1990 Jan - Who cited this? | PubMed ID: 1366366 | Fulltext

Spectral studies of bovine dopamine beta-hydroxylase. Absence of covalently bound pyrroloquinoline quinone.

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Robertson JG, Kumar A, Mancewicz JA, and Villafranca JJ

The Journal of biological chemistry 264(33):19916-21, 1989 Nov 25 - Who cited this? | PubMed ID: 2555337 | Fulltext

Bovine heart pyruvate dehydrogenase kinase stimulation by monovalent ions.

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Robertson JG, Barron LL, and Olson MS

The Journal of biological chemistry 264(20):11626-31, 1989 Jul 15 - Who cited this? | PubMed ID: 2745410 | Fulltext

Characterization of the peribacteroid membrane ATPase of lupin root nodules.

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Domigan NM, Farnden KJ, Robertson JG, and Monk BC

Archives of biochemistry and biophysics 264(2):564-73, 1988 Aug 1 - Who cited this? | PubMed ID: 2969700 | Fulltext

Nodulation inhibition by Rhizobium leguminosarum multicopy nodABC genes and analysis of early stages of plant infection.

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Knight CD, Rossen L, Robertson JG, Wells B, and Downie JA

Journal of bacteriology 166(2):552-8, 1986 May - Who cited this? | PubMed ID: 3009408 | Fulltext

Effects of alpha-ketoisovalerate on bovine heart pyruvate dehydrogenase complex and pyruvate dehydrogenase kinase.

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Robertson JG, Barron LL, and Olson MS

The Journal of biological chemistry 261(1):76-81, 1986 Jan 5 - Who cited this? | PubMed ID: 3941088 | Fulltext

Preservation of corneal collagen fibril structure using low-temperature procedures for electron microscopy.

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Craig AS, Robertson JG, and Parry DA

Journal of ultrastructure and molecular structure research 96(1-3):172-5, 1986 - Who cited this? | PubMed ID: 3119734 | Fulltext

Monoclonal antibodies to antigens in the peribacteroid membrane from Rhizobium-induced root nodules of pea cross-react with plasma membranes and Golgi bodies.

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Brewin NJ, Robertson JG, Wood EA, Wells B, Larkins AP, Galfre G, and Butcher GW

The EMBO journal 4(3):605-11, 1985 Mar - Who cited this? | PubMed ID: 15926221 | Fulltext

The legume-Rhizobium symbiosis: a cell surface interaction.

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Robertson JG, Wells B, Brewin NJ, Wood E, Knight CD, and Downie JA

Journal of cell science. Supplement 2:317-31, 1985 - Who cited this? | PubMed ID: 3912399 | Fulltext

Rhizobium leguminosarum genes involved in early stages of nodulation.

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Downie JA, Rossen L, Knight CD, Robertson JG, Wells B, and Johnston AW

Journal of cell science. Supplement 2:347-54, 1985 - Who cited this? | PubMed ID: 3867677 | Fulltext

Mg2+ adenosine triphosphatase from cell envelopes of free-living and bacteroid forms of Rhizobium lupini strain NZP2257.

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Robertson JG, Thomas JE, Gowing LR, and Boland MJ

Archives of biochemistry and biophysics 232(1):337-47, 1984 Jul - Who cited this? | PubMed ID: 6146293 | Fulltext

Division of peribacteroid membranes in root nodules of white clover.

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Robertson JG and Lyttleton P

Journal of cell science 69:147-57, 1984 Jul - Who cited this? | PubMed ID: 6490745 | Fulltext

Coated and smooth vesicles in the biogenesis of cell walls, plasma membranes, infection threads and peribacteroid membranes in root hairs and nodules of white clover.

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Robertson JG and Lyttleton P

Journal of cell science 58:63-78, 1982 Dec - Who cited this? | PubMed ID: 7183700 | Fulltext

Increased membrane potentials of human skeletal muscle fibres in explant tissue culture.

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Harvey AL, Robertson JG, and Witkowski JA

Journal of the neurological sciences 44(2-3):273-4, 1980 Jan - Who cited this? | PubMed ID: 7354372 | Fulltext

Maturation of human skeletal muscle fibres in explant tissue culture.

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Harvey AL, Robertson JG, and Witkowski JA

Journal of the neurological sciences 41(1):115-22, 1979 Mar - Who cited this? | PubMed ID: 438841 | Fulltext

Reduction of acetylcholine sensitivity of chick muscle in culture by myasthenia gravis serum.

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Harvey AL, Robertson JG, Barkas T, Harrison R, Lunt GG, Stephenson FA, Campbell MJ, and Teague RH

Clinical and experimental immunology 34(3):411-6, 1978 Dec - Who cited this? | PubMed ID: 743809 | Fulltext

Membranes in lupin root nodules. I. The role of Golgi bodies in the biogenesis of infection threads and peribacteroid membranes.

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Robertson JG, Lyttleton P, Bullivant S, and Grayston GF

Journal of cell science 30:129-49, 1978 Apr - Who cited this? | PubMed ID: 649682 | Fulltext

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