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Papers authored by Rioux JD

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Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases.

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International MHC and Autoimmunity Genetics Network, Rioux JD, Goyette P, Vyse TJ, Hammarström L, Fernando MM, Green T, De Jager PL, Foisy S, Wang J, de Bakker PI, Leslie S, McVean G, Padyukov L, Alfredsson L, Annese V,

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Proceedings of the National Academy of Sciences of the United States of America 106(44):18680-5, 2009 Nov 3 - Who cited this? | PubMed ID: 19846760 | Fulltext

Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor.

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Ban M, Goris A, Lorentzen AR, Baker A, Mihalova T, Ingram G, Booth DR, Heard RN, Stewart GJ, Bogaert E, Dubois B, Harbo HF, Celius EG, Spurkland A, Strange R, Hawkins C,

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European journal of human genetics : EJHG 17(10):1309-13, 2009 Oct - Who cited this? | PubMed ID: 19293837 | Fulltext

Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis.

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Festen EA, Goyette P, Scott R, Annese V, Zhernakova A, Lian J, Lefèbvre C, Brant SR, Cho JH, Silverberg MS, Taylor KD, de Jong DJ, Stokkers PC, McGovern D, Palmieri O, Achkar JP,

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Gut 58(6):799-804, 2009 Jun - Who cited this? | PubMed ID: 19201773 | Fulltext

Corrigendum: Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study.

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Silverberg MS, Cho JH, Rioux JD, McGovern DP, Wu J, Annese V, Achkar JP, Goyette P, Scott R, Xu W, Barmada MM, Klei L, Daly MJ, Abraham C, Bayless TM, Bossa F,

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Nature genetics 41(6):762, 2009 Jun - Who cited this? | PubMed ID: 19471306 | Fulltext

The role of the CD58 locus in multiple sclerosis.

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De Jager PL, Baecher-Allan C, Maier LM, Arthur AT, Ottoboni L, Barcellos L, McCauley JL, Sawcer S, Goris A, Saarela J, Yelensky R, Price A, Leppa V, Patterson N, de Bakker PI, Tran D,

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Proceedings of the National Academy of Sciences of the United States of America 106(13):5264-9, 2009 Mar 31 - Who cited this? | PubMed ID: 19237575 | Fulltext

GWA studies: rewriting the story of IBD.

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Budarf ML, Labbé C, David G, and Rioux JD

Trends in genetics : TIG 25(3):137-46, 2009 Mar - Who cited this? | PubMed ID: 19217684 | Fulltext

Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study.

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Silverberg MS, Cho JH, Rioux JD, McGovern DP, Wu J, Annese V, Achkar JP, Goyette P, Scott R, Xu W, Barmada MM, Klei L, Daly MJ, Abraham C, Bayless TM, Bossa F,

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Nature genetics 41(2):216-20, 2009 Feb - Who cited this? | PubMed ID: 19122664 | Fulltext

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility.

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Villani AC, Lemire M, Fortin G, Louis E, Silverberg MS, Collette C, Baba N, Libioulle C, Belaiche J, Bitton A, Gaudet D, Cohen A, Langelier D, Fortin PR, Wither JE, Sarfati M,

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Nature genetics 41(1):71-6, 2009 Jan - Who cited this? | PubMed ID: 19098911 | Fulltext

Genetic variation in the familial Mediterranean fever gene (MEFV) and risk for Crohn's disease and ulcerative colitis.

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Villani AC, Lemire M, Louis E, Silverberg MS, Collette C, Fortin G, Nimmo ER, Renaud Y, Brunet S, Libioulle C, Belaiche J, Bitton A, Gaudet D, Cohen A, Langelier D, Rioux JD,

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PLoS ONE 4(9):e7154, 2009 - Who cited this? | PubMed ID: 19784369 | Fulltext

Autoimmune diseases: insights from genome-wide association studies.

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Lettre G and Rioux JD

Human molecular genetics 17(R2):R116-21, 2008 Oct 15 - Who cited this? | PubMed ID: 18852199 | Fulltext

Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.

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Graham RR, Cotsapas C, Davies L, Hackett R, Lessard CJ, Leon JM, Burtt NP, Guiducci C, Parkin M, Gates C, Plenge RM, Behrens TW, Wither JE, Rioux JD, Fortin PR, Graham DC,

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Nature genetics 40(9):1059-61, 2008 Sep - Who cited this? | PubMed ID: 19165918 | Fulltext

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease.

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McCarroll SA, Huett A, Kuballa P, Chilewski SD, Landry A, Goyette P, Zody MC, Hall JL, Brant SR, Cho JH, Duerr RH, Silverberg MS, Taylor KD, Rioux JD, Altshuler D, Daly MJ,

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Nature genetics 40(9):1107-12, 2008 Sep - Who cited this? | PubMed ID: 19165925 | Fulltext

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease.

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McCarroll SA, Huett A, Kuballa P, Chilewski SD, Landry A, Goyette P, Zody MC, Hall JL, Brant SR, Cho JH, Duerr RH, Silverberg MS, Taylor KD, Rioux JD, Altshuler D, Daly MJ,

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Nature genetics, 2008 Aug 24 - Who cited this? | PubMed ID: 18724369 | Fulltext

Genome-wide association studies: a new window into immune-mediated diseases.

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Xavier RJ and Rioux JD

Nature reviews. Immunology 8(8):631, 2008 Aug - Who cited this? | PubMed ID: 18654571 | Fulltext

Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.

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Graham RR, Cotsapas C, Davies L, Hackett R, Lessard CJ, Leon JM, Burtt NP, Guiducci C, Parkin M, Gates C, Plenge RM, Behrens TW, Wither JE, Rioux JD, Fortin PR, Graham DC,

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Nature genetics, 2008 Aug 1 - Who cited this? | PubMed ID: 18677312 | Fulltext

MAST3: a novel IBD risk factor that modulates TLR4 signaling.

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Labbé C, Goyette P, Lefebvre C, Stevens C, Green T, Tello-Ruiz MK, Cao Z, Landry AL, Stempak J, Annese V, Latiano A, Brant SR, Duerr RH, Taylor KD, Cho JH, Steinhart AH,

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Genes and immunity, 2008 Jul 24 - Who cited this? | PubMed ID: 18650832 | Fulltext

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.

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Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmada MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO,

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Nature genetics, 2008 Jun 29 - Who cited this? | PubMed ID: 18587394 | Fulltext

Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesis.

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Xavier RJ, Huett A, and Rioux JD

Gut 57(6):717-20, 2008 Jun - Who cited this? | PubMed ID: 18272545 | Fulltext

Defining the role of the MHC in autoimmunity: a review and pooled analysis.

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Fernando MM, Stevens CR, Walsh EC, De Jager PL, Goyette P, Plenge RM, Vyse TJ, and Rioux JD

PLoS genetics 4(4), 2008 Apr - Who cited this? | PubMed ID: 18437207 | Fulltext

Integrating risk factors: HLA-DRB1*1501 and Epstein-Barr virus in multiple sclerosis.

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De Jager PL, Simon KC, Munger KL, Rioux JD, Hafler DA, and Ascherio A

Neurology 70(13 Pt 2):1113, 2008 Mar 25 - Who cited this? | PubMed ID: 18272866 | Fulltext

Association of LY9 in UK and Canadian SLE families.

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Graham DS, Vyse TJ, Fortin PR, Montpetit A, Cai YC, Lim S, McKenzie T, Farwell L, Rhodes B, Chad L, Hudson TJ, Sharpe A, Terhorst C, Greenwood CM, Wither J, Rioux JD,

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Genes and immunity 9(2):93-102, 2008 Mar - Who cited this? | PubMed ID: 18216865 | Fulltext

An SNP linkage scan identifies significant Crohn's disease loci on chromosomes 13q13.3 and, in Jewish families, on 1p35.2 and 3q29.

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Shugart YY, Silverberg MS, Duerr RH, Taylor KD, Wang MH, Zarfas K, Schumm LP, Bromfield G, Steinhart AH, Griffiths AM, Kane SV, Barmada MM, Rotter JI, Mei L, Bernstein CN, Bayless TM,

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Genes and immunity 9(2):161-7, 2008 Mar - Who cited this? | PubMed ID: 18246054 | Fulltext

ATG16L1 and IL23R Are Associated With Inflammatory Bowel Diseases but Not With Celiac Disease in The Netherlands.

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Weersma RK, Zhernakova A, Nolte IM, Lefebvre C, Rioux JD, Mulder F, van Dullemen HM, Kleibeuker JH, Wijmenga C, and Dijkstra G

The American journal of gastroenterology 103(3):621-7, 2008 Mar - Who cited this? | PubMed ID: 18047540 | Fulltext

Gene-centric association mapping of chromosome 3p implicates MST1 in IBD pathogenesis.

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Goyette P, Lefebvre C, Ng A, Brant SR, Cho JH, Duerr RH, Silverberg MS, Taylor KD, Latiano A, Aumais G, Deslandres C, Jobin G, Annese V, Daly MJ, Xavier RJ, and Rioux JD

Mucosal immunology 1(2):131-8, 2008 Mar - Who cited this? | PubMed ID: 19079170 | Fulltext

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

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, Harley JB, Alarcón-Riquelme ME, Criswell LA, Jacob CO, Kimberly RP, Moser KL, Tsao BP, Vyse TJ, Langefeld CD, Nath SK, Guthridge JM, Cobb BL, Mirel DB, Marion MC, Williams AH,

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Nature genetics 40(2):204, 2008 Feb - Who cited this? | PubMed ID: 18204446 | Fulltext

Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus.

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Graham DS, Graham RR, Manku H, Wong AK, Whittaker JC, Gaffney PM, Moser KL, Rioux JD, Altshuler D, Behrens TW, and Vyse TJ

Nature genetics 40(1):83, 2008 Jan - Who cited this? | PubMed ID: 18059267 | Fulltext

Identification of a chromosome 8p locus for early-onset coronary heart disease in a French Canadian population.

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Engert JC, Lemire M, Faith J, Brisson D, Fujiwara TM, Roslin NM, Brewer CG, Montpetit A, Darmond-Zwaig C, Renaud Y, Doré C, Bailey SD, Verner A, Tremblay G, St-Pierre J, Bétard C,

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European journal of human genetics : EJHG 16(1):105-14, 2008 Jan - Who cited this? | PubMed ID: 17805225 | Fulltext

Impaired Autophagy of an Intracellular Pathogen Induced by a Crohn's Disease Associated ATG16L1 Variant.

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Kuballa P, Huett A, Rioux JD, Daly MJ, and Xavier RJ

PLoS ONE 3(10):e3391, 2008 - Who cited this? | PubMed ID: 18852889 | Fulltext

Identification of Two Independent Risk Factors for Lupus within the MHC in United Kingdom Families.

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Fernando MM, Stevens CR, Sabeti PC, Walsh EC, McWhinnie AJ, Shah A, Green T, Rioux JD, and Vyse TJ

PLoS genetics 3(11):e192, 2007 Nov - Who cited this? | PubMed ID: 17997607 | Fulltext

Risk alleles for multiple sclerosis identified by a genomewide study.

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, Hafler DA, Compston A, Sawcer S, Lander ES, Daly MJ, De Jager PL, de Bakker PI, Gabriel SB, Mirel DB, Ivinson AJ, Pericak-Vance MA, Gregory SG, Rioux JD, McCauley JL, Haines JL,

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The New England journal of medicine 357(9):851, 2007 Aug 30 - Who cited this? | PubMed ID: 17660530 | Fulltext

Assessment of reliability and validity of IBD phenotyping within the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK) IBD Genetics Consortium (IBDGC).

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Dassopoulos T, Nguyen GC, Bitton A, Bromfield GP, Schumm LP, Wu Y, Elkadri A, Regueiro M, Siemanowski B, Torres EA, Gregory FJ, Kane SV, Harrell LE, Franchimont D, Achkar JP, Griffiths A,

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Inflammatory bowel diseases 13(8):975, 2007 Aug - Who cited this? | PubMed ID: 17427244 | Fulltext

The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases.

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De Jager PL, Franchimont D, Waliszewska A, Bitton A, Cohen A, Langelier D, Belaiche J, Vermeire S, Farwell L, Goris A, Libioulle C, Jani N, Dassopoulos T, Bromfield GP, Dubois B, Cho JH,

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Genes and immunity 8(5):387-97, 2007 Jul - Who cited this? | PubMed ID: 17538633 | Fulltext

Prevalence of CARD15/NOD2 mutations in Caucasian healthy people.

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Hugot JP, Zaccaria I, Cavanaugh J, Yang H, Vermeire S, Lappalainen M, Schreiber S, Annese V, Jewell DP, Fowler EV, Brant SR, Silverberg MS, Cho J, Rioux JD, Satsangi J, Parkes M,

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The American journal of gastroenterology 102(6):1259-67, 2007 Jun - Who cited this? | PubMed ID: 17319929 | Fulltext

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.

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Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, Green T, Kuballa P, Barmada MM, Datta LW, Shugart YY, Griffiths AM, Targan SR, Ippoliti AF, Bernard EJ, Mei L,

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Nature genetics 39(5):596-604, 2007 May - Who cited this? | PubMed ID: 17435756 | Fulltext

Refined genomic localization and ethnic differences observed for the IBD5 association with Crohn's disease.

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Silverberg MS, Duerr RH, Brant SR, Bromfield G, Datta LW, Jani N, Kane SV, Rotter JI, Philip Schumm L, Hillary Steinhart A, Taylor KD, Yang H, Cho JH, Rioux JD, Daly MJ, and NIDDK IBD Genetics Consortium

European journal of human genetics : EJHG 15(3):328-35, 2007 Mar - Who cited this? | PubMed ID: 17213842 | Fulltext

A second major histocompatibility complex susceptibility locus for multiple sclerosis.

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Yeo TW, De Jager PL, Gregory SG, Barcellos LF, Walton A, Goris A, Fenoglio C, Ban M, Taylor CJ, Goodman RS, Walsh E, Wolfish CS, Horton R, Traherne J, Beck S, Trowsdale J,

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Annals of neurology 61(3):228-36, 2007 Mar - Who cited this? | PubMed ID: 17252545 | Fulltext

IBD5 is associated with an extensive complicated Crohn's disease feature: implications from genotype-phenotype analysis.

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Brescianini S, Trinh T, Stoll M, Schreiber S, Rioux JD, and Daly MJ

Gut 56(1):149-50, 2007 Jan - Who cited this? | PubMed ID: 17172589 | Fulltext

Molecular pathogenesis of inflammatory bowel disease: genotypes, phenotypes and personalized medicine.

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Goyette P, Labbé C, Trinh TT, Xavier RJ, and Rioux JD

Annals of medicine 39(3):177-99, 2007 - Who cited this? | PubMed ID: 17457716 | Fulltext

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.

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Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, Steinhart AH, Abraham C, Regueiro M, Griffiths A, Dassopoulos T, Bitton A, Yang H, Targan S, Datta LW, Kistner EO,

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Science (New York, N.Y.) 314(5804):1461-3, 2006 Dec 1 - Who cited this? | PubMed ID: 17068223 | Fulltext

Genetic variation in myosin IXB is associated with ulcerative colitis.

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van Bodegraven AA, Curley CR, Hunt KA, Monsuur AJ, Linskens RK, Onnie CM, Crusius JB, Annese V, Latiano A, Silverberg MS, Bitton A, Fisher SA, Steinhart AH, Forbes A, Sanderson J, Prescott NJ,

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Gastroenterology 131(6):1768-74, 2006 Dec - Who cited this? | PubMed ID: 17087940 | Fulltext

A functional candidate screen for coeliac disease genes.

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Curley CR, Monsuur AJ, Wapenaar MC, Rioux JD, and Wijmenga C

European journal of human genetics : EJHG 14(11):1215-22, 2006 Nov - Who cited this? | PubMed ID: 16835590 | Fulltext

A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC.

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de Bakker PI, McVean G, Sabeti PC, Miretti MM, Green T, Marchini J, Ke X, Monsuur AJ, Whittaker P, Delgado M, Morrison J, Richardson A, Walsh EC, Gao X, Galver L, Hart J,

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Nature genetics 38(10):1166-72, 2006 Oct - Who cited this? | PubMed ID: 16998491 | Fulltext

Direct or indirect association in a complex disease: the role of SLC22A4 and SLC22A5 functional variants in Crohn disease.

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Fisher SA, Hampe J, Onnie CM, Daly MJ, Curley C, Purcell S, Sanderson J, Mansfield J, Annese V, Forbes A, Lewis CM, Schreiber S, Rioux JD, and Mathew CG

Human mutation 27(8):778-85, 2006 Aug - Who cited this? | PubMed ID: 16835882 | Fulltext

Haplotype-based association analysis of 56 functional candidate genes in the IBD6 locus on chromosome 19.

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Tello-Ruiz MK, Curley C, Delmonte T, Giallourakis C, Kirby A, Miller K, Wild G, Cohen A, Langelier D, Latiano A, Wedemeyer N, Lander E, Schreiber S, Annese V, Daly MJ, and Rioux JD

European journal of human genetics : EJHG 14(6):780, 2006 Jun - Who cited this? | PubMed ID: 16570073 | Fulltext

The role of inflammatory bowel disease susceptibility loci in multiple sclerosis and systemic lupus erythematosus.

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De Jager PL, Graham R, Farwell L, Sawcer S, Richardson A, Behrens TW, Compston A, Hafler DA, Kere J, Vyse TJ, and Rioux JD

Genes and immunity 7(4):327-34, 2006 Jun - Who cited this? | PubMed ID: 16642031 | Fulltext

Inflammatory bowel disease characteristics among African Americans, Hispanics, and non-Hispanic Whites: characterization of a large North American cohort.

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Nguyen GC, Torres EA, Regueiro M, Bromfield G, Bitton A, Stempak J, Dassopoulos T, Schumm P, Gregory FJ, Griffiths AM, Hanauer SB, Hanson J, Harris ML, Kane SV, Orkwis HK, Lahaie R,

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The American journal of gastroenterology 101(5):1012-23, 2006 May - Who cited this? | PubMed ID: 16696785 | Fulltext

Evidence of transmission ratio distortion of DLG5 R30Q variant in general and implication of an association with Crohn disease in men.

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Friedrichs F, Brescianini S, Annese V, Latiano A, Berger K, Kugathasan S, Broeckel U, Nikolaus S, Daly MJ, Schreiber S, Rioux JD, and Stoll M

Human genetics 119(3):305-11, 2006 Apr - Who cited this? | PubMed ID: 16446977 | Fulltext

Identifying susceptibility genes for immunological disorders: patterns, power, and proof.

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Plenge R and Rioux JD

Immunological reviews 210:40-51, 2006 Apr - Who cited this? | PubMed ID: 16623763 | Fulltext

Genetic variation in toll-like receptor 9 and susceptibility to systemic lupus erythematosus.

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De Jager PL, Richardson A, Vyse TJ, and Rioux JD

Arthritis and rheumatism 54(4):1279-82, 2006 Apr - Who cited this? | PubMed ID: 16575840 | Fulltext

Evaluating the role of the 620W allele of protein tyrosine phosphatase PTPN22 in Crohn's disease and multiple sclerosis.

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De Jager PL, Sawcer S, Waliszewska A, Farwell L, Wild G, Cohen A, Langelier D, Bitton A, Compston A, Hafler DA, and Rioux JD

European journal of human genetics : EJHG 14(3):317-21, 2006 Mar - Who cited this? | PubMed ID: 16391555 | Fulltext

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