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Papers authored by Rae JM

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Lack of association between oestrogen receptor polymorphisms and change in bone mineral density with tamoxifen therapy.

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Henry NL, Nguyen A, Azzouz F, Li L, Robarge J, Philips S, Cao D, Skaar TC, Rae JM, Storniolo AM, Flockhart DA, Hayes DF, and Stearns V

British journal of cancer 102(2):294-300, 2010 Jan 19 - Who cited this? | PubMed ID: 19953095 | Fulltext

CYP2D6 testing for breast cancer patients: is there more to the story?.

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Henry NL, Hayes DF, and Rae JM

Oncology (Williston Park, N.Y.) 23(14):1236, 1243, 1249, 2009 Dec - Who cited this? | PubMed ID: 20120836 | Fulltext

Myeloperoxidase Genotypes and Enhanced Efficacy of Chemotherapy for Early-Stage Breast Cancer in SWOG-8897.

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Ambrosone CB, Barlow WE, Reynolds W, Livingston RB, Yeh IT, Choi JY, Davis W, Rae JM, Tang L, Hutchins LR, Ravdin PM, Martino S, Osborne CK, Lyss AP, Hayes DF, and Albain KS

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27(30):4973-9, 2009 Oct 20 - Who cited this? | PubMed ID: 19752340 | Fulltext

Association between CYP2D6 genotype and tamoxifen-induced hot flashes in a prospective cohort.

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Lynn Henry N, Rae JM, Li L, Azzouz F, Skaar TC, Desta Z, Sikora MJ, Philips S, Nguyen AT, Storniolo AM, Hayes DF, Flockhart DA, Stearns V, and Consortium on Breast Cancer Pharmacogenomics Investigators

Breast cancer research and treatment 117(3):571-5, 2009 Oct - Who cited this? | PubMed ID: 19153830 | Fulltext

Nitric oxide synthase variants and disease-free survival among treated and untreated breast cancer patients in a Southwest Oncology Group clinical trial.

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Choi JY, Barlow WE, Albain KS, Hong CC, Blanco JG, Livingston RB, Davis W, Rae JM, Yeh IT, Hutchins LF, Ravdin PM, Martino S, Lyss AP, Osborne CK, Abeloff MD, Hayes DF,

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Clinical cancer research : an official journal of the American Association for Cancer Research 15(16):5258-66, 2009 Aug 15 - Who cited this? | PubMed ID: 19671875 | Fulltext

Cytochrome P450 2D6 activity predicts discontinuation of tamoxifen therapy in breast cancer patients.

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Rae JM, Sikora MJ, Henry NL, Li L, Kim S, Oesterreich S, Skaar TC, Nguyen AT, Desta Z, Storniolo AM, Flockhart DA, Hayes DF, Stearns V, and COBRA investigators

The pharmacogenomics journal 9(4):258-64, 2009 Aug - Who cited this? | PubMed ID: 19421167 | Fulltext

Pharmacogenetics of Tamoxifen: Who Should Undergo CYP2D6 Genetic Testing?.

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Higgins MJ, Rae JM, Flockhart DA, Hayes DF, and Stearns V

Journal of the National Comprehensive Cancer Network : JNCCN 7(2):203-13, 2009 Feb - Who cited this? | PubMed ID: 19200418 | Fulltext

Nuclear receptor coregulator SNP discovery and impact on breast cancer risk.

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Hartmaier RJ, Tchatchou S, Richter AS, Wang J, McGuire SE, Skaar TC, Rae JM, Hemminki K, Sutter C, Ditsch N, Bugert P, Weber BH, Niederacher D, Arnold N, Varon-Mateeva R, Wappenschmidt B,

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BMC cancer 9:438, 2009 - Who cited this? | PubMed ID: 20003447 | Fulltext

Cytochrome P450 2D6 and Homeobox 13/Interleukin-17B Receptor: Combining Inherited and Tumor Gene Markers for Prediction of Tamoxifen Resistance.

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Goetz MP, Suman VJ, Couch FJ, Ames MM, Rae JM, Erlander MG, Ma XJ, Sgroi DC, Reynolds CA, Lingle WL, Weinshilboum RM, Flockhart DA, Desta Z, Perez EA, and Ingle JN

Clinical cancer research : an official journal of the American Association for Cancer Research 14(18):5864, 2008 Sep 15 - Who cited this? | PubMed ID: 18794098 | Fulltext

The Endocannabinoid Anandamide is a Substrate for the Human Polymorphic Cytochrome P450 2D6.

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Snider NT, Sikora MJ, Sridar C, Feuerstein TJ, Rae JM, and Hollenberg PF

The Journal of pharmacology and experimental therapeutics, 2008 Aug 12 - Who cited this? | PubMed ID: 18698000 | Fulltext

Monitoring serial changes in circulating human breast cancer cells in murine xenograft models.

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Eliane JP, Repollet M, Luker KE, Brown M, Rae JM, Dontu G, Schott AF, Wicha M, Doyle GV, Hayes DF, and Luker GD

Cancer research 68(14):5529-32, 2008 Jul 15 - Who cited this? | PubMed ID: 18632603 | Fulltext

The androgen metabolite 5alpha-androstane-3beta,17beta-diol (3betaAdiol) induces breast cancer growth via estrogen receptor: implications for aromatase inhibitor resistance.

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Sikora MJ, Cordero KE, Larios JM, Johnson MD, Lippman ME, and Rae JM

Breast cancer research and treatment, 2008 Jun 4 - Who cited this? | PubMed ID: 18521740 | Fulltext

A transcriptional fingerprint of estrogen in human breast cancer predicts patient survival.

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Yu J, Yu J, Cordero KE, Johnson MD, Ghosh D, Rae JM, Chinnaiyan AM, and Lippman ME

Neoplasia (New York, N.Y.) 10(1):79, 2008 Jan - Who cited this? | PubMed ID: 18231641 | Fulltext

The role of single nucleotide polymorphisms in breast cancer metastasis.

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Rae JM, Skaar TC, Hilsenbeck SG, and Oesterreich S

Breast cancer research : BCR 10(1):301, 2008 - Who cited this? | PubMed ID: 18226176 | Fulltext

An expression signature of estrogen-regulated genes predicts disease-free survival in tamoxifen-treated patients better than progesterone receptor status.

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Lippman ME, Rae JM, and Chinnaiyan AM

Transactions of the American Clinical and Climatological Association 119:77-90; discussion 90-2, 2008 - Who cited this? | PubMed ID: 18596862 | Fulltext

Pharmacogenetics and breast cancer endocrine therapy: CYP2D6 as a predictive factor for tamoxifen metabolism and drug response?.

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Stearns V and Rae JM

Expert reviews in molecular medicine 10:e34, 2008 - Who cited this? | PubMed ID: 19019258 | Fulltext

MDA-MB-435 cells are derived from M14 melanoma cells--a loss for breast cancer, but a boon for melanoma research.

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Rae JM, Creighton CJ, Meck JM, Haddad BR, and Johnson MD

Breast cancer research and treatment 104(1):13-9, 2007 Jul - Who cited this? | PubMed ID: 17004106 | Fulltext

Expression levels and activation of a PXR variant are directly related to drug resistance in osteosarcoma cell lines.

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Mensah-Osman EJ, Thomas DG, Tabb MM, Larios JM, Hughes DP, Giordano TJ, Lizyness ML, Rae JM, Blumberg B, Hollenberg PF, and Baker LH

Cancer 109(5):957-65, 2007 Mar 1 - Who cited this? | PubMed ID: 17279585 | Fulltext

The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen.

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Goetz MP, Knox SK, Suman VJ, Rae JM, Safgren SL, Ames MM, Visscher DW, Reynolds C, Couch FJ, Lingle WL, Weinshilboum RM, Fritcher EG, Nibbe AM, Desta Z, Nguyen A, Flockhart DA,

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Breast cancer research and treatment 101(1):113-21, 2007 Jan - Who cited this? | PubMed ID: 17115111 | Fulltext

Endoxifen, a secondary metabolite of tamoxifen, and 4-OH-tamoxifen induce similar changes in global gene expression patterns in MCF-7 breast cancer cells.

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Lim YC, Li L, Desta Z, Zhao Q, Rae JM, Flockhart DA, and Skaar TC

The Journal of pharmacology and experimental therapeutics 318(2):503-12, 2006 Aug - Who cited this? | PubMed ID: 16690721 | Fulltext

Combination vinorelbine and capecitabine for metastatic breast cancer using a non-body surface area dosing scheme.

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Schott AF, Rae JM, Griffith KA, Hayes DF, Sterns V, and Baker LH

Cancer chemotherapy and pharmacology 58(1):129-35, 2006 Jul - Who cited this? | PubMed ID: 16283312 | Fulltext

GREB1 is a novel androgen-regulated gene required for prostate cancer growth.

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Rae JM, Johnson MD, Cordero KE, Scheys JO, Larios JM, Gottardis MM, Pienta KJ, and Lippman ME

The Prostate 66(8):886-94, 2006 Jun 1 - Who cited this? | PubMed ID: 16496412 | Fulltext

Activation of mitogen-activated protein kinase in estrogen receptor alpha-positive breast cancer cells in vitro induces an in vivo molecular phenotype of estrogen receptor alpha-negative human breast tumors.

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Creighton CJ, Hilger AM, Murthy S, Rae JM, Chinnaiyan AM, and El-Ashry D

Cancer research 66(7):3903, 2006 Apr 1 - Who cited this? | PubMed ID: 16585219 | Fulltext

Genes regulated by estrogen in breast tumor cells in vitro are similarly regulated in vivo in tumor xenografts and human breast tumors.

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Creighton CJ, Cordero KE, Larios JM, Miller RS, Johnson MD, Chinnaiyan AM, Lippman ME, and Rae JM

Genome biology 7(4):R28, 2006 - Who cited this? | PubMed ID: 16606439 | Fulltext

When will tumor gene expression profiling be incorporated into clinical breast cancer decision making?.

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Creighton CJ and Rae JM

Breast cancer research : BCR 8(4):302, 2006 - Who cited this? | PubMed ID: 16834787 | Fulltext

Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes.

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Goetz MP, Rae JM, Suman VJ, Safgren SL, Ames MM, Visscher DW, Reynolds C, Couch FJ, Lingle WL, Flockhart DA, Desta Z, Perez EA, and Ingle JN

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 23(36):9312, 2005 Dec 20 - Who cited this? | PubMed ID: 16361630 | Fulltext

GREB 1 is a critical regulator of hormone dependent breast cancer growth.

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Rae JM, Johnson MD, Scheys JO, Cordero KE, Larios JM, and Lippman ME

Breast cancer research and treatment 92(2):141-9, 2005 Jul - Who cited this? | PubMed ID: 15986123 | Fulltext

Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients.

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Nowell SA, Ahn J, Rae JM, Scheys JO, Trovato A, Sweeney C, MacLeod SL, Kadlubar FF, and Ambrosone CB

Breast cancer research and treatment 91(3):249-58, 2005 Jun - Who cited this? | PubMed ID: 15952058 | Fulltext

(-)-Gossypol enhances response to radiation therapy and results in tumor regression of human prostate cancer.

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Xu L, Yang D, Wang S, Tang W, Liu M, Davis M, Chen J, Rae JM, Lawrence T, and Lippman ME

Molecular cancer therapeutics 4(2):197, 2005 Feb - Who cited this? | PubMed ID: 15713891 | Fulltext

CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment.

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Jin Y, Desta Z, Stearns V, Ward B, Ho H, Lee KH, Skaar T, Storniolo AM, Li L, Araba A, Blanchard R, Nguyen A, Ullmer L, Hayden J, Lemler S, Weinshilboum RM,

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Journal of the National Cancer Institute 97(1):30, 2005 Jan 5 - Who cited this? | PubMed ID: 15632378 | Fulltext

CYP2D6 genotype and tamoxifen response.

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Rae JM, Goetz MP, Hayes DF, Ingle JN, Li L, Storniolo AM, Stearns V, and Flockhart DA

Breast cancer research : BCR 7(5):E6, 2005 - Who cited this? | PubMed ID: 16168100 | Fulltext

What does an orphan G-protein-coupled receptor have to do with estrogen?.

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Rae JM and Johnson MD

Breast cancer research : BCR 7(6):243-4, 2005 - Who cited this? | PubMed ID: 16280047 | Fulltext

Metabolism of N,N',N"-triethylenethiophosphoramide by CYP2B1 and CYP2B6 results in the inactivation of both isoforms by two distinct mechanisms.

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Harleton E, Webster M, Bumpus NN, Kent UM, Rae JM, and Hollenberg PF

The Journal of pharmacology and experimental therapeutics 310(3):1011-9, 2004 Sep - Who cited this? | PubMed ID: 15121764 | Fulltext

EGFR and EGFRvIII expression in primary breast cancer and cell lines.

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Rae JM, Scheys JO, Clark KM, Chadwick RB, Kiefer MC, and Lippman ME

Breast cancer research and treatment 87(1):87-95, 2004 Sep - Who cited this? | PubMed ID: 15377854 | Fulltext

Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen.

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Johnson MD, Zuo H, Lee KH, Trebley JP, Rae JM, Weatherman RV, Desta Z, Flockhart DA, and Skaar TC

Breast cancer research and treatment 85(2):151-9, 2004 May - Who cited this? | PubMed ID: 15111773 | Fulltext

Evaluation of novel epidermal growth factor receptor tyrosine kinase inhibitors.

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Rae JM and Lippman ME

Breast cancer research and treatment 83(2):99-107, 2004 Jan - Who cited this? | PubMed ID: 14997040 | Fulltext

LCC15-MB cells are MDA-MB-435: a review of misidentified breast and prostate cell lines.

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Thompson EW, Waltham M, Ramus SJ, Hutchins AM, Armes JE, Campbell IG, Williams ED, Thompson PR, Rae JM, Johnson MD, and Clarke R

Clinical & experimental metastasis 21(6):535-41, 2004 - Who cited this? | PubMed ID: 15679051 | Fulltext

Common origins of MDA-MB-435 cells from various sources with those shown to have melanoma properties.

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Rae JM, Ramus SJ, Waltham M, Armes JE, Campbell IG, Clarke R, Barndt RJ, Johnson MD, and Thompson EW

Clinical & experimental metastasis 21(6):543-52, 2004 - Who cited this? | PubMed ID: 15679052 | Fulltext

Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine.

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Stearns V, Johnson MD, Rae JM, Morocho A, Novielli A, Bhargava P, Hayes DF, Desta Z, and Flockhart DA

Journal of the National Cancer Institute 95(23):1758-64, 2003 Dec 3 - Who cited this? | PubMed ID: 14652237 | Fulltext

Genotyping for polymorphic drug metabolizing enzymes from paraffin-embedded and immunohistochemically stained tumor samples.

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Rae JM, Cordero KE, Scheys JO, Lippman ME, Flockhart DA, and Johnson MD

Pharmacogenetics 13(8):501-7, 2003 Aug - Who cited this? | PubMed ID: 12893988 | Fulltext

Sequence diversity and functional characterization of the 5'-regulatory region of human CYP2C19.

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Arefayene M, Skaar TC, Zhao X, Rae JM, Tanus-Santos JE, Brinkmann U, Brehm I, Salat U, Nguyen A, Desta Z, and Flockhart DA

Pharmacogenetics 13(4):199-206, 2003 Apr - Who cited this? | PubMed ID: 12668916 | Fulltext

Cytochrome P450 3A pharmacogenetics: the road that needs traveled.

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Flockhart DA and Rae JM

The pharmacogenomics journal 3(1):3-5, 2003 - Who cited this? | PubMed ID: 12629575 | Fulltext

Triethylenethiophosphoramide is a specific inhibitor of cytochrome P450 2B6: implications for cyclophosphamide metabolism.

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Rae JM, Soukhova NV, Flockhart DA, and Desta Z

Drug metabolism and disposition: the biological fate of chemicals 30(5):525-30, 2002 May - Who cited this? | PubMed ID: 11950782 | Fulltext

Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: studies with cDNA and oligonucleotide expression arrays.

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Rae JM, Johnson MD, Lippman ME, and Flockhart DA

The Journal of pharmacology and experimental therapeutics 299(3):849-57, 2001 Dec - Who cited this? | PubMed ID: 11714868 | Fulltext

Epithelioid leiomyoma: a case report.

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Musso LA and Rae JM

The Australasian journal of dermatology 23(3):116-8, 1982 Dec - Who cited this? | PubMed ID: 7183303 | Fulltext

LSD, suggestion and hypnosis.

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Solursh LP and Rae JM

International journal of neuropsychiatry 2(1):60-4, 1966 Feb - Who cited this? | PubMed ID: 5907815 | Fulltext

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