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Papers authored by Punnonen J

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EpCAM-specific vaccine response by modified antigen and chimeric costimulatory molecule in cynomolgus monkeys.

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Neighbors M, Apt D, Chang JC, Brinkman A, Sipos-Solman I, Ong R, Leong S, and Punnonen J

Journal of immunotherapy (Hagerstown, Md. : 1997) 31(7):644, 2008 Sep - Who cited this? | PubMed ID: 18600180 | Fulltext

Hypoallergens for allergen-specific immunotherapy by directed molecular evolution of mite group 2 allergens.

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Gafvelin G, Parmley S, Neimert-Andersson T, Blank U, Eriksson TL, van Hage M, and Punnonen J

The Journal of biological chemistry 282(6):3778-87, 2007 Feb 9 - Who cited this? | PubMed ID: 17170112 | Fulltext

A chimeric tetravalent dengue DNA vaccine elicits neutralizing antibody to all four virus serotypes in rhesus macaques.

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Raviprakash K, Apt D, Brinkman A, Skinner C, Yang S, Dawes G, Ewing D, Wu SJ, Bass S, Punnonen J, and Porter K

Virology 353(1):166-73, 2006 Sep 15 - Who cited this? | PubMed ID: 16814355 | Fulltext

Tetravalent neutralizing antibody response against four dengue serotypes by a single chimeric dengue envelope antigen.

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Apt D, Raviprakash K, Brinkman A, Semyonov A, Yang S, Skinner C, Diehl L, Lyons R, Porter K, and Punnonen J

Vaccine 24(3):335-44, 2006 Jan 16 - Who cited this? | PubMed ID: 16125280 | Fulltext

Diverse plasmid DNA vectors by directed molecular evolution of cytomegalovirus promoters.

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Wright A, Semyonov A, Dawes G, Crameri A, Lyons R, Stemmer WP, Apt D, and Punnonen J

Human gene therapy 16(7):881-92, 2005 Jul - Who cited this? | PubMed ID: 16000069 | Fulltext

DNA shuffling and screening strategies for improving vaccine efficacy.

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Locher CP, Paidhungat M, Whalen RG, and Punnonen J

DNA and cell biology 24(4):256-63, 2005 Apr - Who cited this? | PubMed ID: 15812242 | Fulltext

Development of novel vaccines using DNA shuffling and screening strategies.

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Locher CP, Soong NW, Whalen RG, and Punnonen J

Current opinion in molecular therapeutics 6(1):34-9, 2004 Feb - Who cited this? | PubMed ID: 15011779 | Fulltext

Optimized expression and specific activity of IL-12 by directed molecular evolution.

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Leong SR, Chang JC, Ong R, Dawes G, Stemmer WP, and Punnonen J

Proceedings of the National Academy of Sciences of the United States of America 100(3):1163-8, 2003 Feb 4 - Who cited this? | PubMed ID: 12529500 | Fulltext

Chimeric co-stimulatory molecules that selectively act through CD28 or CTLA-4 on human T cells.

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Lazetic S, Leong SR, Chang JC, Ong R, Dawes G, and Punnonen J

The Journal of biological chemistry 277(41):38660-8, 2002 Oct 11 - Who cited this? | PubMed ID: 12167647 | Fulltext

DNA shuffling and vaccines.

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Whalen RG, Kaiwar R, Soong NW, and Punnonen J

Current opinion in molecular therapeutics 3(1):31-6, 2001 Feb - Who cited this? | PubMed ID: 11249729 | Fulltext

Monocyte-derived CD1a+ and CD1a- dendritic cell subsets differ in their cytokine production profiles, susceptibilities to transfection, and capacities to direct Th cell differentiation.

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Chang CC, Wright A, and Punnonen J

Journal of immunology (Baltimore, Md. : 1950) 165(7):3584-91, 2000 Oct 1 - Who cited this? | PubMed ID: 11034359 | Fulltext

Interleukin-15 up-regulates the expression of CD154 on synovial fluid T cells.

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Möttönen M, Isomäki P, Luukkainen R, Toivanen P, Punnonen J, and Lassila O

Immunology 100(2):238-44, 2000 Jun - Who cited this? | PubMed ID: 10886401 | Fulltext

Regulation of UT-OC-3 ovarian carcinoma cells by cytokines: inhibitory effects on cell proliferation and activation of transcription factors AP-1 and NF-kappaB.

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Seppänen M, Lin L, Punnonen J, Grénman S, Punnonen R, and Vihko KK

European journal of endocrinology / European Federation of Endocrine Societies 142(4):393-401, 2000 Apr - Who cited this? | PubMed ID: 10754482 | Fulltext

Molecular breeding of allergy vaccines and antiallergic cytokines.

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Punnonen J

International archives of allergy and immunology 121(3):173-82, 2000 Mar - Who cited this? | PubMed ID: 10729775 | Fulltext

Evolution of a cytokine using DNA family shuffling.

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Chang CC, Chen TT, Cox BW, Dawes GN, Stemmer WP, Punnonen J, and Patten PA

Nature biotechnology 17(8):793-7, 1999 Aug - Who cited this? | PubMed ID: 10429246 | Fulltext

Synovial fluid T cells from patients with rheumatoid arthritis are refractory to the T helper type 2 differentiation-inducing effects of interleukin-4.

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Isomäki P, Luukkainen R, Lassila O, Toivanen P, and Punnonen J

Immunology 96(3):358-64, 1999 Mar - Who cited this? | PubMed ID: 10233716 | Fulltext

Expression of soluble human signaling lymphocytic activation molecule in vivo.

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Isomäki P, Aversa G, Chang CC, Luukkainen R, Nikkari S, Toivanen P, de Vries JE, and Punnonen J

The Journal of allergy and clinical immunology 103(1 Pt 1):114-8, 1999 Jan - Who cited this? | PubMed ID: 9893194 | Fulltext

Interleukin-10 inhibits the capacity of synovial macrophages to function as antigen-presenting cells.

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Möttönen M, Isomäki P, Saario R, Toivanen P, Punnonen J, and Lassila O

British journal of rheumatology 37(11):1207-14, 1998 Nov - Who cited this? | PubMed ID: 9851271 | Fulltext

Cytokine production profiles in the peritoneal fluids of patients with malignant or benign gynecologic tumors.

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Punnonen R, Teisala K, Kuoppala T, Bennett B, and Punnonen J

Cancer 83(4):788-96, 1998 Aug 15 - Who cited this? | PubMed ID: 9708947 | Fulltext

Inhibitory effects of cytokines on ovarian and endometrial carcinoma cells in vitro with special reference to induction of specific transcriptional regulators.

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Seppänen M, Henttinen T, Lin L, Punnonen J, Grénman S, Punnonen R, and Vihko KK

Oncology research 10(11-12):575-89, 1998 - Who cited this? | PubMed ID: 10367939 | Fulltext

The relative contribution of IL-4 and IL-13 to human IgE synthesis induced by activated CD4+ or CD8+ T cells.

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Punnonen J, Yssel H, and de Vries JE

The Journal of allergy and clinical immunology 100(6 Pt 1):792-801, 1997 Dec - Who cited this? | PubMed ID: 9438489 | Fulltext

Pro- and anti-inflammatory cytokines in rheumatoid arthritis.

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Isomäki P and Punnonen J

Annals of medicine 29(6):499-507, 1997 Dec - Who cited this? | PubMed ID: 9562516 | Fulltext

Reversal of human allergic T helper 2 responses by engagement of signaling lymphocytic activation molecule.

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Carballido JM, Aversa G, Kaltoft K, Cocks BG, Punnonen J, Yssel H, Thestrup-Pedersen K, and de Vries JE

Journal of immunology (Baltimore, Md. : 1950) 159(9):4316-21, 1997 Nov 1 - Who cited this? | PubMed ID: 9379027 | Fulltext

Regulation of copper/zinc and manganese superoxide dismutase by UVB irradiation, oxidative stress and cytokines.

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Isoherranen K, Peltola V, Laurikainen L, Punnonen J, Laihia J, Ahotupa M, and Punnonen K

Journal of photochemistry and photobiology. B, Biology 40(3):288-93, 1997 Oct - Who cited this? | PubMed ID: 9372618 | Fulltext

Increased expression of signaling lymphocytic activation molecule in patients with rheumatoid arthritis and its role in the regulation of cytokine production in rheumatoid synovium.

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Isomäki P, Aversa G, Cocks BG, Luukkainen R, Saario R, Toivanen P, de Vries JE, and Punnonen J

Journal of immunology (Baltimore, Md. : 1950) 159(6):2986-93, 1997 Sep 15 - Who cited this? | PubMed ID: 9300723 | Fulltext

SLAM and its role in T cell activation and Th cell responses.

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Aversa G, Carballido J, Punnonen J, Chang CC, Hauser T, Cocks BG, and De Vries JE

Immunology and cell biology 75(2):202-5, 1997 Apr - Who cited this? | PubMed ID: 9107577 | Fulltext

Soluble and membrane-bound forms of signaling lymphocytic activation molecule (SLAM) induce proliferation and Ig synthesis by activated human B lymphocytes.

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Punnonen J, Cocks BG, Carballido JM, Bennett B, Peterson D, Aversa G, and de Vries JE

The Journal of experimental medicine 185(6):993-1004, 1997 Mar 17 - Who cited this? | PubMed ID: 9091591 | Fulltext

IL-4 synergizes with IL-10 and anti-CD40 MoAbs to induce B-cell differentiation in patients with common variable immunodeficiency.

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Punnonen J, Kainulainen L, Ruuskanen O, Nikoskelainen J, and Arvilommi H

Scandinavian journal of immunology 45(2):203-12, 1997 Feb - Who cited this? | PubMed ID: 9042433 | Fulltext

[Common variable Immunodeficiency syndrome].

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Kainulainen L, Ruuskanen O, Nikoskelainen J, Svedström E, Liippo K, Punnonen J, and Arvilommi H

Duodecim; laaketieteellinen aikakauskirja 113(3):209-16, 1997 - Who cited this? | PubMed ID: 11370029 | Fulltext

Regulation of proliferation of UM-SCV-1A and UM-SCV-6 vulvar carcinoma cells by cytokines.

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Vihko KK, Seppänen M, Henttinen T, Punnonen J, Grénman S, and Punnonen R

Cancer immunology, immunotherapy : CII 43(6):368-74, 1997 Jan - Who cited this? | PubMed ID: 9067409 | Fulltext

The presence of interleukin-13 in rheumatoid synovium and its antiinflammatory effects on synovial fluid macrophages from patients with rheumatoid arthritis.

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Isomäki P, Luukkainen R, Toivanen P, and Punnonen J

Arthritis and rheumatism 39(10):1693-702, 1996 Oct - Who cited this? | PubMed ID: 8843860 | Fulltext

Expression of bcl-2 in rheumatoid arthritis.

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Isomäki P, Söderström KO, Punnonen J, Roivainen A, Luukkainen R, Merilahti-Palo R, Nikkari S, Lassila O, and Toivanen P

British journal of rheumatology 35(7):611-9, 1996 Jul - Who cited this? | PubMed ID: 8670592 | Fulltext

Increased levels of interleukin-6 and interleukin-10 in the peritoneal fluid of patients with endometriosis.

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Punnonen J, Teisala K, Ranta H, Bennett B, and Punnonen R

American journal of obstetrics and gynecology 174(5):1522-6, 1996 May - Who cited this? | PubMed ID: 9065123 | Fulltext

Interleukin-10 functions as an antiinflammatory cytokine in rheumatoid synovium.

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Isomaki P, Luukkainen R, Saario R, Toivanen P, and Punnonen J

Arthritis and rheumatism 39(3):386-95, 1996 Mar - Who cited this? | PubMed ID: 8607887 | Fulltext

IL-4 induces germ-line IgE heavy chain gene transcription in human fetal pre-B cells. Evidence for differential expression of functional IL-4 and IL-13 receptors during B cell ontogeny.

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Punnonen J, Cocks BG, and de Vries JE

Journal of immunology (Baltimore, Md. : 1950) 155(9):4248-54, 1995 Nov 1 - Who cited this? | PubMed ID: 7594582 | Fulltext

Inhibition of human IgE synthesis in vitro and in SCID-hu mice by an interleukin-4 receptor antagonist.

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Carballido JM, Aversa G, Schols D, Punnonen J, and de Vries JE

International archives of allergy and immunology 107(1-3):304-7, 1995 - Who cited this? | PubMed ID: 7613155 | Fulltext

CD40 ligand-CD40 interaction in Ig isotype switching in mature and immature human B cells.

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Aversa G, Punnonen J, Carballido JM, Cocks BG, and de Vries JE

Seminars in immunology 6(5):295-301, 1994 Oct - Who cited this? | PubMed ID: 7532459 | Fulltext

Role of interleukin-4 and interleukin-13 in synthesis of IgE and expression of CD23 by human B cells.

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Punnonen J, Aversa G, Cocks BG, and de Vries JE

Allergy 49(8):576-86, 1994 Sep - Who cited this? | PubMed ID: 7544548 | Fulltext

Lymphoid and myeloid differentiation of fetal liver CD34+lineage- cells in human thymic organ culture.

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Bárcena A, Galy AH, Punnonen J, Muench MO, Schols D, Roncarolo MG, de Vries JE, and Spits H

The Journal of experimental medicine 180(1):123-32, 1994 Jul 1 - Who cited this? | PubMed ID: 7516402 | Fulltext

Effects of cis- and trans-urocanic acids on the secretion of interleukin-1 beta and tumour necrosis factor-alpha by human peripheral blood monocytes.

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Laihia JK, Jansén CT, Uksila J, Punnonen J, Neuvonen K, Pasanen P, and Ayräs P

Acta dermato-venereologica 74(4):266-8, 1994 Jul - Who cited this? | PubMed ID: 7976083 | Fulltext

IL-13 induces proliferation, Ig isotype switching, and Ig synthesis by immature human fetal B cells.

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Punnonen J and de Vries JE

Journal of immunology (Baltimore, Md. : 1950) 152(3):1094-102, 1994 Feb 1 - Who cited this? | PubMed ID: 7507958 | Fulltext

Contact-mediated signals and cytokines involved in B-cell activation and isotype switching in pre-B and mature B cells.

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Aversa G, Cocks BG, Punnonen J, Carballido JM, and de Vries JE

Research in immunology 145(3):222-6; discussion 244-9, 1994 - Who cited this? | PubMed ID: 7527579 | Fulltext

An interleukin 4 (IL-4) mutant protein inhibits both IL-4 or IL-13-induced human immunoglobulin G4 (IgG4) and IgE synthesis and B cell proliferation: support for a common component shared by IL-4 and IL-13 receptors.

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Aversa G, Punnonen J, Cocks BG, de Waal Malefyt R, Vega F, Zurawski SM, Zurawski G, and de Vries JE

The Journal of experimental medicine 178(6):2213-8, 1993 Dec 1 - Who cited this? | PubMed ID: 7504061 | Fulltext

The role of T/B cell interactions and cytokines in the regulation of human IgE synthesis.

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de Vries JE, Punnonen J, Cocks BG, and Aversa G

Seminars in immunology 5(6):431-9, 1993 Dec - Who cited this? | PubMed ID: 7510139 | Fulltext

Brequinar sodium, mycophenolic acid, and cyclosporin A inhibit different stages of IL-4- or IL-13-induced human IgG4 and IgE production in vitro.

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Chang CC, Aversa G, Punnonen J, Yssel H, and de Vries JE

Annals of the New York Academy of Sciences 696:108-22, 1993 Nov 30 - Who cited this? | PubMed ID: 7509129 | Fulltext

Human pre-B cells differentiate into Ig-secreting plasma cells in the presence of interleukin-4 and activated CD4+ T cells or their membranes.

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Punnonen J, Aversa G, and de Vries JE

Blood 82(9):2781-9, 1993 Nov 1 - Who cited this? | PubMed ID: 7693047 | Fulltext

Regulation of the human IgE response by IL4 and IL13.

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de Vries JE, Punnonen J, Cocks BG, de Waal Malefyt R, and Aversa G

Research in immunology 144(8):597-601, 1993 Oct - Who cited this? | PubMed ID: 7905652 | Fulltext

IL-10 and viral IL-10 prevent IL-4-induced IgE synthesis by inhibiting the accessory cell function of monocytes.

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Punnonen J, de Waal Malefyt R, van Vlasselaer P, Gauchat JF, and de Vries JE

Journal of immunology (Baltimore, Md. : 1950) 151(3):1280-9, 1993 Aug 1 - Who cited this? | PubMed ID: 8393044 | Fulltext

Characterization of a novel CD2+ human thymic B cell subset.

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Punnonen J and de Vries JE

Journal of immunology (Baltimore, Md. : 1950) 151(1):100-10, 1993 Jul 1 - Who cited this? | PubMed ID: 7686927 | Fulltext

Human Ig production and isotype switching in severe combined immunodeficient-human mice.

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Vandekerckhove BA, Jones D, Punnonen J, Schols D, Lin HC, Duncan B, Bacchetta R, de Vries JE, and Roncarolo MG

Journal of immunology (Baltimore, Md. : 1950) 151(1):128-37, 1993 Jul 1 - Who cited this? | PubMed ID: 8326122 | Fulltext

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