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Papers authored by Prins RM

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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

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Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, Fantin VR, Jang HG, Jin S, Keenan MC, Marks KM, Prins RM, Ward PS, Yen KE, Liau LM, Rabinowitz JD,

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Nature 462(7274):739-44, 2009 Dec 10 - Who cited this? | PubMed ID: 19935646 | Fulltext

Enhanced antitumor activity induced by adoptive T-cell transfer and adjunctive use of the histone deacetylase inhibitor LAQ824.

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Vo DD, Prins RM, Begley JL, Donahue TR, Morris LF, Bruhn KW, de la Rocha P, Yang MY, Mok S, Garban HJ, Craft N, Economou JS, Marincola FM, Wang E, and Ribas A

Cancer research 69(22):8693-9, 2009 Nov 15 - Who cited this? | PubMed ID: 19861533 | Fulltext

The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis.

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Guo D, Hildebrandt IJ, Prins RM, Soto H, Mazzotta MM, Dang J, Czernin J, Shyy JY, Watson AD, Phelps M, Radu CG, Cloughesy TF, and Mischel PS

Proceedings of the National Academy of Sciences of the United States of America 106(31):12932-7, 2009 Aug 4 - Who cited this? | PubMed ID: 19625624 | Fulltext

EGFR Signaling Through an Akt-SREBP-1-Dependent, Rapamycin-Resistant Pathway Sensitizes Glioblastomas to Antilipogenic Therapy.

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Guo D, Prins RM, Dang J, Kuga D, Iwanami A, Soto H, Lin KY, Huang TT, Akhavan D, Hock MB, Zhu S, Kofman AA, Bensinger SJ, Yong WH, Vinters HV, Horvath S,

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Science signaling 2(101):ra82, 2009 - Who cited this? | PubMed ID: 20009104 | Fulltext

Immunosensitization with a Bcl-2 small molecule inhibitor.

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Begley J, Vo DD, Morris LF, Bruhn KW, Prins RM, Mok S, Koya RC, Garban HJ, Comin-Anduix B, Craft N, and Ribas A

Cancer immunology, immunotherapy : CII, 2008 Sep 20 - Who cited this? | PubMed ID: 18807035 | Fulltext

Anti-tumor activity and trafficking of self, tumor-specific T cells against tumors located in the brain.

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Prins RM, Shu CJ, Radu CG, Vo DD, Khan-Farooqi H, Soto H, Yang MY, Lin MS, Shelly S, Witte ON, Ribas A, and Liau LM

Cancer immunology, immunotherapy : CII 57(9):1279, 2008 Sep - Who cited this? | PubMed ID: 18253732 | Fulltext

Cytomegalovirus immunity after vaccination with autologous glioblastoma lysate.

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Prins RM, Cloughesy TF, and Liau LM

The New England journal of medicine 359(5):539-41, 2008 Jul 31 - Who cited this? | PubMed ID: 18669440 | Fulltext

Lentiviral Vectors with CMV or MHCII Promoters Administered In Vivo: Immune Reactivity Versus Persistence of Expression.

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Kimura T, Koya RC, Anselmi L, Sternini C, Wang HJ, Comin-Anduix B, Prins RM, Faure-Kumar E, Rozengurt N, Cui Y, Kasahara N, and Stripecke R

Molecular therapy : the journal of the American Society of Gene Therapy 15(7):1390-9, 2007 Jul - Who cited this? | PubMed ID: 17505480 | Fulltext

NK and CD4 cells collaborate to protect against melanoma tumor formation in the brain.

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Prins RM, Vo DD, Khan-Farooqi H, Yang MY, Soto H, Economou JS, Liau LM, and Ribas A

Journal of immunology (Baltimore, Md. : 1950) 177(12):8448-55, 2006 Dec 15 - Who cited this? | PubMed ID: 17142742 | Fulltext

Immunotherapy for patients with malignant glioma: from theoretical principles to clinical applications.

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Yang MY, Zetler PM, Prins RM, Khan-Farooqi H, and Liau LM

Expert review of neurotherapeutics 6(10):1481-94, 2006 Oct - Who cited this? | PubMed ID: 17078788 | Fulltext

The TLR-7 agonist, imiquimod, enhances dendritic cell survival and promotes tumor antigen-specific T cell priming: relation to central nervous system antitumor immunity.

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Prins RM, Craft N, Bruhn KW, Khan-Farooqi H, Koya RC, Stripecke R, Miller JF, and Liau LM

Journal of immunology (Baltimore, Md. : 1950) 176(1):157, 2006 Jan 1 - Who cited this? | PubMed ID: 16365406 | Fulltext

Central nervous system tumor immunity generated by a recombinant listeria monocytogenes vaccine targeting tyrosinase related protein-2 and real-time imaging of intracranial tumor burden.

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Prins RM, Bruhn KW, Craft N, Lin JW, Kim CH, Odesa SK, Miller JF, and Liau LM

Neurosurgery 58(1):169-78; discussion 169-78, 2006 Jan - Who cited this? | PubMed ID: 16385341 | Fulltext

Tumor immunology, immunomics and targeted immunotherapy for central nervous system malignancies.

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Khan-Farooqi HR, Prins RM, and Liau LM

Neurological research 27(7):692-702, 2005 Oct - Who cited this? | PubMed ID: 16197806 | Fulltext

Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment.

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Liau LM, Prins RM, Kiertscher SM, Odesa SK, Kremen TJ, Giovannone AJ, Lin JW, Chute DJ, Mischel PS, Cloughesy TF, and Roth MD

Clinical cancer research : an official journal of the American Association for Cancer Research 11(15):5515-25, 2005 Aug 1 - Who cited this? | PubMed ID: 16061868 | Fulltext

Cellular immunity and immunotherapy of brain tumors.

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Prins RM and Liau LM

Frontiers in bioscience : a journal and virtual library 9:3124-36, 2004 Sep 1 - Who cited this? | PubMed ID: 15353342 | Fulltext

Characterization of defective CD4-CD8- T cells in murine tumors generated independent of antigen specificity.

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Prins RM, Incardona F, Lau R, Lee P, Claus S, Zhang W, Black KL, and Wheeler CJ

Journal of immunology (Baltimore, Md. : 1950) 172(3):1602-11, 2004 Feb 1 - Who cited this? | PubMed ID: 14734741 | Fulltext

Modulation of major histocompatibility complex Class I molecules and major histocompatibility complex-bound immunogenic peptides induced by interferon-alpha and interferon-gamma treatment of human glioblastoma multiforme.

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Yang I, Kremen TJ, Giovannone AJ, Paik E, Odesa SK, Prins RM, and Liau LM

Journal of neurosurgery 100(2):310-9, 2004 Feb - Who cited this? | PubMed ID: 15086239 | Fulltext

Immunotherapeutic targeting of shared melanoma-associated antigens in a murine glioma model.

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Prins RM, Odesa SK, and Liau LM

Cancer research 63(23):8487-91, 2003 Dec 1 - Who cited this? | PubMed ID: 14679014 | Fulltext

Immunology and immunotherapy in neurosurgical disease.

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Prins RM and Liau LM

Neurosurgery 53(1):144-52; discussion 152-3, 2003 Jul - Who cited this? | PubMed ID: 12823883 | Fulltext

Contrasting effects of interleukin-2 secretion by rat glioma cells contingent upon anatomical location: accelerated tumorigenesis in the central nervous system and complete rejection in the periphery.

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Graf MR, Prins RM, Poulsen GA, and Merchant RE

Journal of neuroimmunology 140(1-2):49-60, 2003 Jul - Who cited this? | PubMed ID: 12864971 | Fulltext

Thymic function and output of recent thymic emigrant T cells during intracranial glioma progression.

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Prins RM, Graf MR, Merchant RE, Black KL, and Wheeler CJ

Journal of neuro-oncology 64(1-2):45-54, 2003 - Who cited this? | PubMed ID: 12952285 | Fulltext

Irradiated tumor cell vaccine for treatment of an established glioma. I. Successful treatment with combined radiotherapy and cellular vaccination.

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Graf MR, Prins RM, Hawkins WT, and Merchant RE

Cancer immunology, immunotherapy : CII 51(4):179-89, 2002 Jun - Who cited this? | PubMed ID: 12012105 | Fulltext

Irradiated tumor cell vaccine for treatment of an established glioma. II. Expansion of myeloid suppressor cells that promote tumor progression.

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Prins RM, Scott GP, Merchant RE, and Graf MR

Cancer immunology, immunotherapy : CII 51(4):190-9, 2002 Jun - Who cited this? | PubMed ID: 12012106 | Fulltext

Cytotoxic T cells infiltrating a glioma express an aberrant phenotype that is associated with decreased function and apoptosis.

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Prins RM, Graf MR, and Merchant RE

Cancer immunology, immunotherapy : CII 50(6):285-92, 2001 Aug - Who cited this? | PubMed ID: 11570581 | Fulltext

Vaccination of malignant glioma patients with peptide-pulsed dendritic cells elicits systemic cytotoxicity and intracranial T-cell infiltration.

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Yu JS, Wheeler CJ, Zeltzer PM, Ying H, Finger DN, Lee PK, Yong WH, Incardona F, Thompson RC, Riedinger MS, Zhang W, Prins RM, and Black KL

Cancer research 61(3):842-7, 2001 Feb 1 - Who cited this? | PubMed ID: 11221866 | Fulltext

IL-6 secretion by a rat T9 glioma clone induces a neutrophil-dependent antitumor response with resultant cellular, antiglioma immunity.

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Graf MR, Prins RM, and Merchant RE

Journal of immunology (Baltimore, Md. : 1950) 166(1):121-9, 2001 Jan 1 - Who cited this? | PubMed ID: 11123284 | Fulltext

Treatment of intracranial gliomas with bone marrow-derived dendritic cells pulsed with tumor antigens.

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Liau LM, Black KL, Prins RM, Sykes SN, DiPatre PL, Cloughesy TF, Becker DP, and Bronstein JM

Journal of neurosurgery 90(6):1115-24, 1999 Jun - Who cited this? | PubMed ID: 10350260 | Fulltext

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