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Papers authored by Prasad VR

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The telomerase-specific T motif is a restrictive determinant of repetitive reverse transcription by human telomerase.

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Drosopoulos WC and Prasad VR

Molecular and cellular biology 30(2):447-59, 2010 Jan - Who cited this? | PubMed ID: 19917726 | Fulltext

Influence of cation-pi interactions to the structural stability of prokaryotic and eukaryotic translation elongation factors.

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Prasad VR and Sathpathy S

Protoplasma 238(1-4):11-20, 2009 Dec - Who cited this? | PubMed ID: 19653064 | Fulltext

Influence of cation-pi interactions to the structural stability of prokaryotic and eukaryotic translation elongation factors.

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Anbarasu A, Prasad VR, Satpathy S, and Sethumadhavan R

Protoplasma 238(1-4):21, 2009 Dec - Who cited this? | PubMed ID: 19728033 | Fulltext

Analysis of 2-LTR Circle Junctions of Viral DNA in Infected Cells.

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Mandal D and Prasad VR

Methods in molecular biology (Clifton, N.J.) 485:73-85, 2009 - Who cited this? | PubMed ID: 19020819 | Fulltext

Methods to Study Monocyte Migration Induced by HIV-Infected Cells.

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Rao VR, Eugenin EA, Berman JW, and Prasad VR

Methods in molecular biology (Clifton, N.J.) 485:295-309, 2009 - Who cited this? | PubMed ID: 19020833 | Fulltext

HIV-1 clade-specific differences in the induction of neuropathogenesis.

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Rao VR, Sas AR, Eugenin EA, Siddappa NB, Bimonte-Nelson H, Berman JW, Ranga U, Tyor WR, and Prasad VR

The Journal of neuroscience : the official journal of the Society for Neuroscience 28(40):10010-6, 2008 Oct 1 - Who cited this? | PubMed ID: 18829958 | Fulltext

Probing the active site steric flexibility of HIV-1 reverse transcriptase: different constraints for DNA- versus RNA-templated synthesis.

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Silverman AP, Garforth SJ, Prasad VR, and Kool ET

Biochemistry 47(16):4800, 2008 Apr 22 - Who cited this? | PubMed ID: 18366188 | Fulltext

Exceptional molecular and coreceptor-requirement properties of molecular clones isolated from an Human Immunodeficiency Virus Type-1 subtype C infection.

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Dash PK, Siddappa NB, Mangaiarkarasi A, Mahendarkar AV, Roshan P, Anand KK, Mahadevan A, Satishchandra P, Shankar SK, Prasad VR, and Ranga U

Retrovirology 5:25, 2008 - Who cited this? | PubMed ID: 18328091 | Fulltext

Utilization of a Deoxynucleoside Diphosphate Substrate by HIV Reverse Transcriptase.

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Garforth SJ, Parniak MA, and Prasad VR

PLoS ONE 3(4):e2074, 2008 - Who cited this? | PubMed ID: 18446195 | Fulltext

Site-directed mutagenesis in the fingers subdomain of HIV-1 reverse transcriptase reveals a specific role for the beta3-beta4 hairpin loop in dNTP selection.

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Garforth SJ, Kim TW, Parniak MA, Kool ET, and Prasad VR

Journal of molecular biology 365(1):38, 2007 Jan 5 - Who cited this? | PubMed ID: 17055529 | Fulltext

The active site residue Valine 867 in human telomerase reverse transcriptase influences nucleotide incorporation and fidelity.

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Drosopoulos WC and Prasad VR

Nucleic acids research 35(4):1155, 2007 - Who cited this? | PubMed ID: 17264120 | Fulltext

Instability of retroviral vectors with HIV-1-specific RT aptamers due to cryptic splice sites in the U6 promoter.

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Braun SE, Shi X, Qiu G, Wong FE, Joshi PJ, Prasad VR, and Johnson RP

AIDS research and therapy 4:24, 2007 - Who cited this? | PubMed ID: 17941994 | Fulltext

Examining interactions of HIV-1 reverse transcriptase with single-stranded template nucleotides by nucleoside analog interference.

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Dash C, Fisher TS, Prasad VR, and Le Grice SF

The Journal of biological chemistry 281(38):27873, 2006 Sep 22 - Who cited this? | PubMed ID: 16867979 | Fulltext

Fiji School of Medicine Diploma in Pharmacy graduates, ten year analysis--where are they now?.

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Bailey MC, Khaiyum E, and Prasad VR

Pacific health dialog : a publication of the Pacific Basin Officers Training Program and the Fiji School of Medicine 13(2):151-4, 2006 Sep - Who cited this? | PubMed ID: 18181406 | Fulltext

Structural features of mouse telomerase RNA are responsible for the lower activity of mouse telomerase versus human telomerase.

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Garforth SJ, Wu YY, and Prasad VR

The Biochemical journal 397(3):399-406, 2006 Aug 1 - Who cited this? | PubMed ID: 16669789 | Fulltext

Structural determinants of slippage-mediated mutations by human immunodeficiency virus type 1 reverse transcriptase.

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Hamburgh ME, Curr KA, Monaghan M, Rao VR, Tripathi S, Preston BD, Sarafianos S, Arnold E, Darden T, and Prasad VR

The Journal of biological chemistry 281(11):7421-8, 2006 Mar 17 - Who cited this? | PubMed ID: 16423828 | Fulltext

Influence of naturally occurring insertions in the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase on polymerase fidelity and mutation frequencies in vitro.

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Curr K, Tripathi S, Lennerstrand J, Larder BA, and Prasad VR

The Journal of general virology 87(Pt 2):419, 2006 Feb - Who cited this? | PubMed ID: 16432030 | Fulltext

Analysis of HIV-1 replication block due to substitutions at F61 residue of reverse transcriptase reveals additional defects involving the RNase H function.

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Mandal D, Dash C, Le Grice SF, and Prasad VR

Nucleic acids research 34(10):2853, 2006 - Who cited this? | PubMed ID: 16723431 | Fulltext

HIV-1 reverse transcriptase mutations that confer decreased in vitro susceptibility to anti-RT DNA aptamer RT1t49 confer cross resistance to other anti-RT aptamers but not to standard RT inhibitors.

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Fisher TS, Joshi P, and Prasad VR

AIDS research and therapy 2:8, 2005 Oct 5 - Who cited this? | PubMed ID: 16207371 | Fulltext

Human telomerase RNA template sequence is a determinant of telomere repeat extension rate.

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Drosopoulos WC, Direnzo R, and Prasad VR

The Journal of biological chemistry 280(38):32801-10, 2005 Sep 23 - Who cited this? | PubMed ID: 16061476 | Fulltext

Aptamers directed to HIV-1 reverse transcriptase display greater efficacy over small hairpin RNAs targeted to viral RNA in blocking HIV-1 replication.

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Joshi PJ, North TW, and Prasad VR

Molecular therapy : the journal of the American Society of Gene Therapy 11(5):677-86, 2005 May - Who cited this? | PubMed ID: 15851006 | Fulltext

Nucleoside-analog resistance mutations in HIV-1 reverse transcriptase and their influence on polymerase fidelity and viral mutation rates.

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Rezende LF and Prasad VR

The international journal of biochemistry & cell biology 36(9):1716-34, 2004 Sep - Who cited this? | PubMed ID: 15183340 | Fulltext

Interaction between human immunodeficiency virus type 1 reverse transcriptase and integrase proteins.

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Hehl EA, Joshi P, Kalpana GV, and Prasad VR

Journal of virology 78(10):5056-67, 2004 May - Who cited this? | PubMed ID: 15113887 | Fulltext

Tat protein of human immunodeficiency virus type 1 subtype C strains is a defective chemokine.

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Ranga U, Shankarappa R, Siddappa NB, Ramakrishna L, Nagendran R, Mahalingam M, Mahadevan A, Jayasuryan N, Satishchandra P, Shankar SK, and Prasad VR

Journal of virology 78(5):2586-90, 2004 Mar - Who cited this? | PubMed ID: 14963162 | Fulltext

Anti-HIV inhibitors based on nucleic acids: emergence of aptamers as potent antivirals.

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Joshi PJ, Fisher TS, and Prasad VR

Current drug targets. Infectious disorders 3(4):383-400, 2003 Dec - Who cited this? | PubMed ID: 14754437 | Fulltext

Mutations proximal to the minor groove-binding track of human immunodeficiency virus type 1 reverse transcriptase differentially affect utilization of RNA versus DNA as template.

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Fisher TS, Darden T, and Prasad VR

Journal of virology 77(10):5837-45, 2003 May - Who cited this? | PubMed ID: 12719577 | Fulltext

Substitutions at Phe61 in the beta3-beta4 hairpin of HIV-1 reverse transcriptase reveal a role for the Fingers subdomain in strand displacement DNA synthesis.

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Fisher TS, Darden T, and Prasad VR

Journal of molecular biology 325(3):443-59, 2003 Jan 17 - Who cited this? | PubMed ID: 12498795 | Fulltext

Potent inhibition of human immunodeficiency virus type 1 replication by template analog reverse transcriptase inhibitors derived by SELEX (systematic evolution of ligands by exponential enrichment).

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Joshi P and Prasad VR

Journal of virology 76(13):6545-57, 2002 Jul - Who cited this? | PubMed ID: 12050367 | Fulltext

Substitutions of Phe61 located in the vicinity of template 5'-overhang influence polymerase fidelity and nucleoside analog sensitivity of HIV-1 reverse transcriptase.

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Fisher TS and Prasad VR

The Journal of biological chemistry 277(25):22345-52, 2002 Jun 21 - Who cited this? | PubMed ID: 11948182 | Fulltext

Mutations that confer resistance to template-analog inhibitors of human immunodeficiency virus (HIV) type 1 reverse transcriptase lead to severe defects in HIV replication.

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Fisher TS, Joshi P, and Prasad VR

Journal of virology 76(8):4068-72, 2002 Apr - Who cited this? | PubMed ID: 11907245 | Fulltext

The effect of increased processivity on overall fidelity of human immunodeficiency virus type 1 reverse transcriptase.

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Rezende LF, Kew Y, and Prasad VR

Journal of biomedical science 8(2):197-205, 2001 - Who cited this? | PubMed ID: 11287751 | Fulltext

Differential influence of nucleoside analog-resistance mutations K65R and L74V on the overall mutation rate and error specificity of human immunodeficiency virus type 1 reverse transcriptase.

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Shah FS, Curr KA, Hamburgh ME, Parniak M, Mitsuya H, Arnez JG, and Prasad VR

The Journal of biological chemistry 275(35):27037-44, 2000 Sep 1 - Who cited this? | PubMed ID: 10833521 | Fulltext

The ankyrin repeat-containing adaptor protein Tvl-1 is a novel substrate and regulator of Raf-1.

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Lin JH, Makris A, McMahon C, Bear SE, Patriotis C, Prasad VR, Brent R, Golemis EA, and Tsichlis PN

The Journal of biological chemistry 274(21):14706-15, 1999 May 21 - Who cited this? | PubMed ID: 10329666 | Fulltext

The influence of 3TC-resistance mutations E89G and M184V in the human immunodeficiency virus reverse transcriptase on mispair extension efficiency.

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Hamburgh ME, Drosopoulos WC, and Prasad VR

Nucleic acids research 26(19):4389-94, 1998 Oct 1 - Who cited this? | PubMed ID: 9742239 | Fulltext

Virtues of being faithful: can we limit the genetic variation in human immunodeficiency virus?.

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Drosopoulos WC, Rezende LF, Wainberg MA, and Prasad VR

Journal of molecular medicine (Berlin, Germany) 76(9):604-12, 1998 Aug - Who cited this? | PubMed ID: 9725762 | Fulltext

The influence of 3TC resistance mutation M184I on the fidelity and error specificity of human immunodeficiency virus type 1 reverse transcriptase.

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Rezende LF, Drosopoulos WC, and Prasad VR

Nucleic acids research 26(12):3066-72, 1998 Jun 15 - Who cited this? | PubMed ID: 9611256 | Fulltext

Increased misincorporation fidelity observed for nucleoside analog resistance mutations M184V and E89G in human immunodeficiency virus type 1 reverse transcriptase does not correlate with the overall error rate measured in vitro.

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Drosopoulos WC and Prasad VR

Journal of virology 72(5):4224-30, 1998 May - Who cited this? | PubMed ID: 9557711 | Fulltext

The impact of multidideoxynucleoside resistance-conferring mutations in human immunodeficiency virus type 1 reverse transcriptase on polymerase fidelity and error specificity.

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Rezende LF, Curr K, Ueno T, Mitsuya H, and Prasad VR

Journal of virology 72(4):2890-5, 1998 Apr - Who cited this? | PubMed ID: 9525609 | Fulltext

Insertions into the beta3-beta4 hairpin loop of HIV-1 reverse transcriptase reveal a role for fingers subdomain in processive polymerization.

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Kew Y, Olsen LR, Japour AJ, and Prasad VR

The Journal of biological chemistry 273(13):7529-37, 1998 Mar 27 - Who cited this? | PubMed ID: 9516454 | Fulltext

Long-term reduction of serum bilirubin levels in Gunn rats by retroviral gene transfer in vivo.

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Tada K, Chowdhury NR, Neufeld D, Bosma PJ, Heard M, Prasad VR, and Chowdhury JR

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 4(1):78-88, 1998 Jan - Who cited this? | PubMed ID: 9457971 | Fulltext

Higher fidelity of RNA-dependent DNA mispair extension by M184V drug-resistant than wild-type reverse transcriptase of human immunodeficiency virus type 1.

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Hsu M, Inouye P, Rezende L, Richard N, Li Z, Prasad VR, and Wainberg MA

Nucleic acids research 25(22):4532-6, 1997 Nov 15 - Who cited this? | PubMed ID: 9358162 | Fulltext

Effects of mutations in Pr160gag-pol upon tRNA(Lys3) and Pr160gag-plo incorporation into HIV-1.

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Mak J, Khorchid A, Cao Q, Huang Y, Lowy I, Parniak MA, Prasad VR, Wainberg MA, and Kleiman L

Journal of molecular biology 265(4):419-31, 1997 Jan 31 - Who cited this? | PubMed ID: 9034361 | Fulltext

Perspective: research highlights at the Albert Einstein College of Medicine Center for AIDS research. Approaches to control drug resistance in HIV: the role of increased polymerase fidelity.

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Prasad VR, Drosopoulos WC, and Hamburgh ME

AIDS research and human retroviruses 12(11):959-63, 1996 Jul 20 - Who cited this? | PubMed ID: 8827210 | Fulltext

Increased polymerase fidelity of E89G, a nucleoside analog-resistant variant of human immunodeficiency virus type 1 reverse transcriptase.

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Drosopoulos WC and Prasad VR

Journal of virology 70(7):4834-8, 1996 Jul - Who cited this? | PubMed ID: 8676518 | Fulltext

The nucleoside analog-resistant E89G mutant of human immunodeficiency virus type 1 reverse transcriptase displays a broader cross-resistance that extends to nonnucleoside inhibitors.

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Kew Y, Salomon H, Olsen LR, Wainberg MA, and Prasad VR

Antimicrobial agents and chemotherapy 40(7):1711-4, 1996 Jul - Who cited this? | PubMed ID: 8807067 | Fulltext

Use of chimeric human immunodeficiency virus types 1 and 2 reverse transcriptases for structure-function analysis and for mapping susceptibility to nonnucleoside inhibitors.

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Yang G, Song Q, Charles M, Drosopoulos WC, Arnold E, and Prasad VR

Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 11(4):326-33, 1996 Apr 1 - Who cited this? | PubMed ID: 8601218 | Fulltext

Bilirubin glucuronidation by intact Gunn rat fibroblasts expressing bilirubin UDP-glucuronosyltransferase.

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Seppen J, Tada K, Hellwig S, Bakker CT, Prasad VR, Roy Chowdhury N, Roy Chowdhury J, Bosma PJ, and Oude Elferink RP

The Biochemical journal 314 ( Pt 2):477-83, 1996 Mar 1 - Who cited this? | PubMed ID: 8670060 | Fulltext

Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase.

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Wainberg MA, Drosopoulos WC, Salomon H, Hsu M, Borkow G, Parniak M, Gu Z, Song Q, Manne J, Islam S, Castriota G, and Prasad VR

Science (New York, N.Y.) 271(5253):1282-5, 1996 Mar 1 - Who cited this? | PubMed ID: 8638110 | Fulltext

Reversal of pulmonary capillary ischemia-reperfusion injury by rolipram, a cAMP phosphodiesterase inhibitor.

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Barnard JW, Seibert AF, Prasad VR, Smart DA, Strada SJ, Taylor AE, and Thompson WJ

Journal of applied physiology (Bethesda, Md. : 1985) 77(2):774-81, 1994 Aug - Who cited this? | PubMed ID: 8002527 | Fulltext

Subunit-selective mutagenesis of Glu-89 residue in human immunodeficiency virus reverse transcriptase. Contribution of p66 and p51 subunits to nucleoside analog sensitivity, divalent cation preference, and steady state kinetic properties.

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Kew Y, Qingbin S, and Prasad VR

The Journal of biological chemistry 269(21):15331-6, 1994 May 27 - Who cited this? | PubMed ID: 7515055 | Fulltext

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