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Papers authored by Poon RY

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Stress-activated mitogen-activated protein kinases c-Jun NH2-terminal kinase and p38 target Cdc25B for degradation.

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Uchida S, Yoshioka K, Kizu R, Nakagama H, Matsunaga T, Ishizaka Y, Poon RY, and Yamashita K

Cancer research 69(16):6438-44, 2009 Aug 15 - Who cited this? | PubMed ID: 19638579 | Fulltext

DNA damage mediated s and g(2) checkpoints in human embryonal carcinoma cells.

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Wang X, Lui VC, Poon RT, Lu P, and Poon RY

Stem cells (Dayton, Ohio) 27(3):568-76, 2009 Mar - Who cited this? | PubMed ID: 19259937 | Fulltext

Generation of an indestructible cyclin B1 by caspase-6-dependent cleavage during mitotic catastrophe.

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Chan YW, Chen Y, and Poon RY

Oncogene 28(2):170-83, 2009 Jan 15 - Who cited this? | PubMed ID: 18820706 | Fulltext

The Kinetics of p53 Activation Versus Cyclin E Accumulation Underlies the Relationship between the Spindle-assembly Checkpoint and the Postmitotic Checkpoint.

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Chan YW, On KF, Chan WM, Wong W, Siu HO, Hau PM, and Poon RY

The Journal of biological chemistry 283(23):15716, 2008 Jun 6 - Who cited this? | PubMed ID: 18400748 | Fulltext

CDK1 inhibitors antagonize the immediate apoptosis triggered by spindle disruption but promote apoptosis following the subsequent rereplication and abnormal mitosis.

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Chan YW, Ma HT, Wong W, Ho CC, On KF, and Poon RY

Cell cycle (Georgetown, Tex.) 7(10):1449-61, 2008 May - Who cited this? | PubMed ID: 18418077 | Fulltext

The multiple checkpoint functions of CHK1 and CHK2 in maintenance of genome stability.

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Chen Y and Poon RY

Frontiers in bioscience : a journal and virtual library 13:5016-29, 2008 - Who cited this? | PubMed ID: 18508566 | Fulltext

Specialized roles of the two mitotic cyclins in somatic cells: cyclin A as an activator of M phase-promoting factor.

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Fung TK, Ma HT, and Poon RY

Molecular biology of the cell 18(5):1861-73, 2007 May - Who cited this? | PubMed ID: 17344473 | Fulltext

Mitotic phosphorylation: breaking the balance of power by a tactical retreat.

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Poon RY

The Biochemical journal 403(2):e5-7, 2007 Apr 15 - Who cited this? | PubMed ID: 17376029 | Fulltext

The p53 Isoform Deltap53 lacks intrinsic transcriptional activity and reveals the critical role of nuclear import in dominant-negative activity.

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Chan WM and Poon RY

Cancer research 67(5):1959-69, 2007 Mar 1 - Who cited this? | PubMed ID: 17332323 | Fulltext

An inducible system for expression and validation of the specificity of short hairpin RNA in mammalian cells.

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Ma HT, On KF, Tsang YH, and Poon RY

Nucleic acids research 35(4):e22, 2007 - Who cited this? | PubMed ID: 17234679 | Fulltext

Polyploidization increases the sensitivity to DNA-damaging agents in mammalian cells.

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Hau PM, Siu WY, Wong N, Lai PB, and Poon RY

FEBS letters 580(19):4727, 2006 Aug 21 - Who cited this? | PubMed ID: 16887121 | Fulltext

Stalled replication induces p53 accumulation through distinct mechanisms from DNA damage checkpoint pathways.

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Ho CC, Siu WY, Lau A, Chan WM, Arooz T, and Poon RY

Cancer research 66(4):2233-41, 2006 Feb 15 - Who cited this? | PubMed ID: 16489026 | Fulltext

Ubiquitination of p53 at multiple sites in the DNA-binding domain.

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Chan WM, Mak MC, Fung TK, Lau A, Siu WY, and Poon RY

Molecular cancer research : MCR 4(1):15-25, 2006 Jan - Who cited this? | PubMed ID: 16446403 | Fulltext

The N-terminal regulatory domain of cyclin A contains redundant ubiquitination targeting sequences and acceptor sites.

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Fung TK, Yam CH, and Poon RY

Cell cycle (Georgetown, Tex.) 4(10):1411-20, 2005 Oct - Who cited this? | PubMed ID: 16123593 | Fulltext

A roller coaster ride with the mitotic cyclins.

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Fung TK and Poon RY

Seminars in cell & developmental biology 16(3):335-42, 2005 Jun - Who cited this? | PubMed ID: 15840442 | Fulltext

The relative contribution of CHK1 and CHK2 to Adriamycin-induced checkpoint.

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Ho CC, Siu WY, Chow JP, Lau A, Arooz T, Tong HY, Ng IO, and Poon RY

Experimental cell research 304(1):1-15, 2005 Mar 10 - Who cited this? | PubMed ID: 15707569 | Fulltext

Subcellular localization of EEN/endophilin A2, a fusion partner gene in leukaemia.

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Cheung N, So CW, Yam JW, So CK, Poon RY, Jin DY, and Chan LC

The Biochemical journal 383(Pt 1):27-35, 2004 Oct 1 - Who cited this? | PubMed ID: 15214844 | Fulltext

Gene mutations and aneuploidy: the instability that causes cancer.

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Woo RA and Poon RY

Cell cycle (Georgetown, Tex.) 3(9):1101-3, 2004 Sep - Who cited this? | PubMed ID: 15326384 | Fulltext

Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation.

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Woo RA and Poon RY

Genes & development 18(11):1317-30, 2004 Jun 1 - Who cited this? | PubMed ID: 15175263 | Fulltext

Topoisomerase poisons differentially activate DNA damage checkpoints through ataxia-telangiectasia mutated-dependent and -independent mechanisms.

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Siu WY, Lau A, Arooz T, Chow JP, Ho HT, and Poon RY

Molecular cancer therapeutics 3(5):621-32, 2004 May - Who cited this? | PubMed ID: 15141020 | Fulltext

How many mutant p53 molecules are needed to inactivate a tetramer?.

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Chan WM, Siu WY, Lau A, and Poon RY

Molecular and cellular biology 24(8):3536-51, 2004 Apr - Who cited this? | PubMed ID: 15060172 | Fulltext

Differential mode of regulation of the checkpoint kinases CHK1 and CHK2 by their regulatory domains.

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Ng CP, Lee HC, Ho CW, Arooz T, Siu WY, Lau A, and Poon RY

The Journal of biological chemistry 279(10):8808-19, 2004 Mar 5 - Who cited this? | PubMed ID: 14681223 | Fulltext

ING1b decreases cell proliferation through p53-dependent and -independent mechanisms.

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Tsang FC, Po LS, Leung KM, Lau A, Siu WY, and Poon RY

FEBS letters 553(3):277, 2003 Oct 23 - Who cited this? | PubMed ID: 14572637 | Fulltext

Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints.

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Chow JP, Siu WY, Ho HT, Ma KH, Ho CC, and Poon RY

The Journal of biological chemistry 278(42):40815-28, 2003 Oct 17 - Who cited this? | PubMed ID: 12912980 | Fulltext

DNA damage during the spindle-assembly checkpoint degrades CDC25A, inhibits cyclin-CDC2 complexes, and reverses cells to interphase.

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Chow JP, Siu WY, Fung TK, Chan WM, Lau A, Arooz T, Ng CP, Yamashita K, and Poon RY

Molecular biology of the cell 14(10):3989-4002, 2003 Oct - Who cited this? | PubMed ID: 14517313 | Fulltext

Cyclin-dependent kinases and S phase control in mammalian cells.

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Woo RA and Poon RY

Cell cycle (Georgetown, Tex.) 2(4):316-24, 2003 - Who cited this? | PubMed ID: 12851482 | Fulltext

Cyclin F is degraded during G2-M by mechanisms fundamentally different from other cyclins.

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Fung TK, Siu WY, Yam CH, Lau A, and Poon RY

The Journal of biological chemistry 277(38):35140-9, 2002 Sep 20 - Who cited this? | PubMed ID: 12122006 | Fulltext

The candidate tumor suppressor ING1b can stabilize p53 by disrupting the regulation of p53 by MDM2.

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Leung KM, Po LS, Tsang FC, Siu WY, Lau A, Ho HT, and Poon RY

Cancer research 62(17):4890, 2002 Sep 1 - Who cited this? | PubMed ID: 12208736 | Fulltext

Regulation of the CDK-related protein kinase PCTAIRE-1 and its possible role in neurite outgrowth in Neuro-2A cells.

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Graeser R, Gannon J, Poon RY, Dubois T, Aitken A, and Hunt T

Journal of cell science 115(Pt 17):3479-90, 2002 Sep 1 - Who cited this? | PubMed ID: 12154078 | Fulltext

Cyclin A in cell cycle control and cancer.

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Yam CH, Fung TK, and Poon RY

Cellular and molecular life sciences : CMLS 59(8):1317-26, 2002 Aug - Who cited this? | PubMed ID: 12363035 | Fulltext

Activation of cyclin-dependent kinases CDC2 and CDK2 in hepatocellular carcinoma.

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Li KK, Ng IO, Fan ST, Albrecht JH, Yamashita K, and Poon RY

Liver 22(3):259-68, 2002 Jun - Who cited this? | PubMed ID: 12100577 | Fulltext

MDM2 and MDMX can interact differently with ARF and members of the p53 family.

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Wang X, Arooz T, Siu WY, Chiu CH, Lau A, Yamashita K, and Poon RY

FEBS letters 490(3):202-8, 2001 Feb 16 - Who cited this? | PubMed ID: 11223036 | Fulltext

A possible role of p73 on the modulation of p53 level through MDM2.

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Wang XQ, Ongkeko WM, Lau AW, Leung KM, and Poon RY

Cancer research 61(4):1598-603, 2001 Feb 15 - Who cited this? | PubMed ID: 11245471 | Fulltext

Cleavage of cyclin A at R70/R71 by the bacterial protease OmpT.

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Yam CH, Siu WY, Kaganovich D, Ruderman JV, and Poon RY

Proceedings of the National Academy of Sciences of the United States of America 98(2):497, 2001 Jan 16 - Who cited this? | PubMed ID: 11136238 | Fulltext

On the concentrations of cyclins and cyclin-dependent kinases in extracts of cultured human cells.

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Arooz T, Yam CH, Siu WY, Lau A, Li KK, and Poon RY

Biochemistry 39(31):9494, 2000 Aug 8 - Who cited this? | PubMed ID: 10924145 | Fulltext

p21 and retinoblastoma protein control the absence of DNA replication in terminally differentiated muscle cells.

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Mal A, Chattopadhyay D, Ghosh MK, Poon RY, Hunter T, and Harter ML

The Journal of cell biology 149(2):281-92, 2000 Apr 17 - Who cited this? | PubMed ID: 10769022 | Fulltext

Degradation of cyclin A does not require its phosphorylation by CDC2 and cyclin-dependent kinase 2.

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Yam CH, Siu WY, Lau A, and Poon RY

The Journal of biological chemistry 275(5):3158-67, 2000 Feb 4 - Who cited this? | PubMed ID: 10652300 | Fulltext

The spindle checkpoint in the dinoflagellate Crypthecodinium cohnii.

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Yeung PK, New DC, Leveson A, Yam CH, Poon RY, and Wong JT

Experimental cell research 254(1):120-9, 2000 Jan 10 - Who cited this? | PubMed ID: 10623472 | Fulltext

G1 versus G2 cell cycle arrest after adriamycin-induced damage in mouse Swiss3T3 cells.

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Siu WY, Yam CH, and Poon RY

FEBS letters 461(3):299-305, 1999 Nov 19 - Who cited this? | PubMed ID: 10567715 | Fulltext

MDM2 and MDMX inhibit the transcriptional activity of ectopically expressed SMAD proteins.

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Yam CH, Siu WY, Arooz T, Chiu CH, Lau A, Wang XQ, and Poon RY

Cancer research 59(20):5075-8, 1999 Oct 15 - Who cited this? | PubMed ID: 10537276 | Fulltext

Differential responses of proliferating versus quiescent cells to adriamycin.

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Siu WY, Arooz T, and Poon RY

Experimental cell research 250(1):131-41, 1999 Jul 10 - Who cited this? | PubMed ID: 10388527 | Fulltext

Regulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2.

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Yam CH, Ng RW, Siu WY, Lau AW, and Poon RY

Molecular and cellular biology 19(1):635-45, 1999 Jan - Who cited this? | PubMed ID: 9858587 | Fulltext

MDM2 and MDMX bind and stabilize the p53-related protein p73.

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Ongkeko WM, Wang XQ, Siu WY, Lau AW, Yamashita K, Harris AL, Cox LS, and Poon RY

Current biology : CB 9(15):829-32, 1999 - Who cited this? | PubMed ID: 10469568 | Fulltext

Characterization of the cullin and F-box protein partner Skp1.

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Ng RW, Arooz T, Yam CH, Chan IW, Lau AW, and Poon RY

FEBS letters 438(3):183-9, 1998 Nov 6 - Who cited this? | PubMed ID: 9827542 | Fulltext

Involvement of p21 and p27 in the regulation of CDK activity and cell cycle progression in the regenerating liver.

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Albrecht JH, Poon RY, Ahonen CL, Rieland BM, Deng C, and Crary GS

Oncogene 16(16):2141-50, 1998 Apr 23 - Who cited this? | PubMed ID: 9572495 | Fulltext

Expression of a novel form of p21Cip1/Waf1 in UV-irradiated and transformed cells.

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Poon RY and Hunter T

Oncogene 16(10):1333-43, 1998 Mar 12 - Who cited this? | PubMed ID: 9546435 | Fulltext

The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells.

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Poon RY, Chau MS, Yamashita K, and Hunter T

Cancer research 57(22):5168-78, 1997 Nov 15 - Who cited this? | PubMed ID: 9371520 | Fulltext

Cdc37: a protein kinase chaperone?.

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Hunter T and Poon RY

Trends in cell biology 7(4):157-61, 1997 Apr - Who cited this? | PubMed ID: 17708934 | Fulltext

Identification of functional domains in the neuronal Cdk5 activator protein.

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Poon RY, Lew J, and Hunter T

The Journal of biological chemistry 272(9):5703-8, 1997 Feb 28 - Who cited this? | PubMed ID: 9038181 | Fulltext

Generation of phosphorylated cyclin-dependent kinase 2 and functional characterization of threonine-160-specific phosphatase KAP.

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Poon RY

Methods in enzymology 283:283-92, 1997 - Who cited this? | PubMed ID: 9251027 | Fulltext

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