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Papers authored by Pearse MJ

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Single dose intranasal immunization with ISCOMATRIX vaccines to elicit antibody-mediated clearance of influenza virus requires delivery to the lower respiratory tract.

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Sanders MT, Deliyannis G, Pearse MJ, McNamara MK, and Brown LE

Vaccine 27(18):2475-82, 2009 Apr 21 - Who cited this? | PubMed ID: 19368789 | Fulltext

Targeting subcapsular antigens for prevention of Klebsiella pneumoniae infections.

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Clements A, Jenney AW, Farn JL, Brown LE, Deliyannis G, Hartland EL, Pearse MJ, Maloney MB, Wesselingh SL, Wijburg OL, and Strugnell RA

Vaccine 26(44):5649-53, 2008 Oct 16 - Who cited this? | PubMed ID: 18725260 | Fulltext

Macrophages are mediators of gastritis in acute Helicobacter pylori infection in C57BL/6 mice.

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Kaparakis M, Walduck AK, Price JD, Pedersen JS, van Rooijen N, Pearse MJ, Wijburg OL, and Strugnell RA

Infection and immunity 76(5):2235-9, 2008 May - Who cited this? | PubMed ID: 18332213 | Fulltext

CD8+ T Cells Are Associated with Severe Gastritis in Helicobacter pylori- Infected Mice in the Absence of CD4+ T Cells.

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Tan MP, Pedersen J, Zhan Y, Lew AM, Pearse MJ, Wijburg OL, and Strugnell RA

Infection and immunity 76(3):1289-97, 2008 Mar - Who cited this? | PubMed ID: 18025102 | Fulltext

Secondary acylation of Klebsiella pneumoniae lipopolysaccharide contributes to sensitivity to antibacterial peptides.

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Clements A, Tull D, Jenney AW, Farn JL, Kim SH, Bishop RE, McPhee JB, Hancock RE, Hartland EL, Pearse MJ, Wijburg OL, Jackson DC, McConville MJ, and Strugnell RA

The Journal of biological chemistry 282(21):15569, 2007 May 25 - Who cited this? | PubMed ID: 17371870 | Fulltext

ISCOM-based vaccines: the second decade.

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Sanders MT, Brown LE, Deliyannis G, and Pearse MJ

Immunology and cell biology 83(2):119-28, 2005 Apr - Who cited this? | PubMed ID: 15748208 | Fulltext

ISCOMATRIX adjuvant for antigen delivery.

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Pearse MJ and Drane D

Advanced drug delivery reviews 57(3):465-74, 2005 Jan 10 - Who cited this? | PubMed ID: 15560952 | Fulltext

Phase 1 study of HPV16-specific immunotherapy with E6E7 fusion protein and ISCOMATRIX adjuvant in women with cervical intraepithelial neoplasia.

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Frazer IH, Quinn M, Nicklin JL, Tan J, Perrin LC, Ng P, O'Connor VM, White O, Wendt N, Martin J, Crowley JM, Edwards SJ, McKenzie AW, Mitchell SV, Maher DW, Pearse MJ,

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Vaccine 23(2):172-81, 2004 Nov 25 - Who cited this? | PubMed ID: 15531034 | Fulltext

Association of antigens to ISCOMATRIX adjuvant using metal chelation leads to improved CTL responses.

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Malliaros J, Quinn C, Arnold FH, Pearse MJ, Drane DP, Stewart TJ, and Macfarlan RI

Vaccine 22(29-30):3968-75, 2004 Sep 28 - Who cited this? | PubMed ID: 15364446 | Fulltext

ISCOMATRIX adjuvant: a potent inducer of humoral and cellular immune responses.

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Pearse MJ and Drane D

Vaccine 22(19):2391-5, 2004 Jun 23 - Who cited this? | PubMed ID: 15193400 | Fulltext

NY-ESO-1 protein formulated in ISCOMATRIX adjuvant is a potent anticancer vaccine inducing both humoral and CD8+ t-cell-mediated immunity and protection against NY-ESO-1+ tumors.

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Maraskovsky E, Sjölander S, Drane DP, Schnurr M, Le TT, Mateo L, Luft T, Masterman KA, Tai TY, Chen Q, Green S, Sjölander A, Pearse MJ, Lemonnier FA, Chen W, Cebon J,

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Clinical cancer research : an official journal of the American Association for Cancer Research 10(8):2879-90, 2004 Apr 15 - Who cited this? | PubMed ID: 15102697 | Fulltext

Targeting gene expression to endothelium in transgenic animals: a comparison of the human ICAM-2, PECAM-1 and endoglin promoters.

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Cowan PJ, Shinkel TA, Fisicaro N, Godwin JW, Bernabéu C, Almendro N, Rius C, Lonie AJ, Nottle MB, Wigley PL, Paizis K, Pearse MJ, and d'Apice AJ

Xenotransplantation 10(3):223-31, 2003 May - Who cited this? | PubMed ID: 12694542 | Fulltext

Effect of DNA concentration on transgenesis rates in mice and pigs.

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Nottle MB, Haskard KA, Verma PJ, Du ZT, Grupen CG, McIlfatrick SM, Ashman RJ, Harrison SJ, Barlow H, Wigley PL, Lyons IG, Cowan PJ, Crawford RJ, Tolstoshev PL, Pearse MJ, Robins AJ,

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Transgenic research 10(6):523-31, 2001 Dec - Who cited this? | PubMed ID: 11817540 | Fulltext

Hyperacute rejection of vascularized heart transplants in BALB/c Gal knockout mice.

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Gock H, Salvaris E, Murray-Segal L, Mottram P, Han W, Pearse MJ, Goodman DJ, Cowan PJ, and d'Apice AJ

Xenotransplantation 7(4):237-46, 2000 Nov - Who cited this? | PubMed ID: 11081758 | Fulltext

The pig analogue of CD59 protects transgenic mouse hearts from injury by human complement.

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Fisicaro N, Aminian A, Hinchliffe SJ, Morgan BP, Pearse MJ, D'Apice AJ, and Cowan PJ

Transplantation 70(6):963-8, 2000 Sep 27 - Who cited this? | PubMed ID: 11014650 | Fulltext

Renal xenografts from triple-transgenic pigs are not hyperacutely rejected but cause coagulopathy in non-immunosuppressed baboons.

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Cowan PJ, Aminian A, Barlow H, Brown AA, Chen CG, Fisicaro N, Francis DM, Goodman DJ, Han W, Kurek M, Nottle MB, Pearse MJ, Salvaris E, Shinkel TA, Stainsby GV, Stewart AB,

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Transplantation 69(12):2504-15, 2000 Jun 27 - Who cited this? | PubMed ID: 10910270 | Fulltext

The intracellular parasite Theileria parva protects infected T cells from apoptosis.

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Heussler VT, Machado J, Fernandez PC, Botteron C, Chen CG, Pearse MJ, and Dobbelaere DA

Proceedings of the National Academy of Sciences of the United States of America 96(13):7312-7, 1999 Jun 22 - Who cited this? | PubMed ID: 10377411 | Fulltext

Anti-xenograft immune responses in alpha 1,3-galactosyltransferase knock-out mice.

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Pearse MJ, Cowan PJ, Shinkel TA, Chen CG, and d'Apice AJ

Sub-cellular biochemistry 32:281-310, 1999 - Who cited this? | PubMed ID: 10392000 | Fulltext

Expression and functional analysis of glycosyl-phosphatidyl inositol-linked CD46 in transgenic mice.

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Shinkel TA, Cowan PJ, Barlow H, Aminian A, Romanella M, Lublin DM, Pearse MJ, and d'Apice AJ

Transplantation 66(11):1401-6, 1998 Dec 15 - Who cited this? | PubMed ID: 9869079 | Fulltext

Xenotransplantation: an update.

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d'Apice AJ, Goodman DJ, and Pearse MJ

Trends in cardiovascular medicine 8(7):319-25, 1998 Oct - Who cited this? | PubMed ID: 14987557 | Fulltext

Anti-Gal antibody-mediated allograft rejection in alpha1,3-galactosyltransferase gene knockout mice: a model of delayed xenograft rejection.

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Pearse MJ, Witort E, Mottram P, Han W, Murray-Segal L, Romanella M, Salvaris E, Shinkel TA, Goodman DJ, and d'Apice AJ

Transplantation 66(6):748-54, 1998 Sep 27 - Who cited this? | PubMed ID: 9771838 | Fulltext

High-level co-expression of complement regulators on vascular endothelium in transgenic mice: CD55 and CD59 provide greater protection from human complement-mediated injury than CD59 alone.

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Cowan PJ, Shinkel TA, Aminian A, Romanella M, Wigley PL, Lonie AJ, Nottle MB, Pearse MJ, and d'Apice AJ

Xenotransplantation 5(3):184-90, 1998 Aug - Who cited this? | PubMed ID: 9741456 | Fulltext

Knock out of alpha1,3-galactosyltransferase or expression of alpha1,2-fucosyltransferase further protects CD55- and CD59-expressing mouse hearts in an ex vivo model of xenograft rejection.

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Cowan PJ, Chen CG, Shinkel TA, Fisicaro N, Salvaris E, Aminian A, Romanella M, Pearse MJ, and d'Apice AJ

Transplantation 65(12):1599-604, 1998 Jun 27 - Who cited this? | PubMed ID: 9665076 | Fulltext

The human ICAM-2 promoter is endothelial cell-specific in vitro and in vivo and contains critical Sp1 and GATA binding sites.

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Cowan PJ, Tsang D, Pedic CM, Abbott LR, Shinkel TA, d'Apice AJ, and Pearse MJ

The Journal of biological chemistry 273(19):11737-44, 1998 May 8 - Who cited this? | PubMed ID: 9565596 | Fulltext

High-level endothelial expression of human CD59 prolongs heart function in an ex vivo model of xenograft rejection.

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Cowan PJ, Somerville CA, Shinkel TA, Katerelos M, Aminian A, Romanella M, Tange MJ, Pearse MJ, and d'Apice AJ

Transplantation 65(6):826-31, 1998 Mar 27 - Who cited this? | PubMed ID: 9539095 | Fulltext

Transgenic expression of human alpha1,2-fucosyltransferase (H-transferase) prolongs mouse heart survival in an ex vivo model of xenograft rejection.

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Chen CG, Salvaris EJ, Romanella M, Aminian A, Katerelos M, Fisicaro N, d'Apice AJ, and Pearse MJ

Transplantation 65(6):832-7, 1998 Mar 27 - Who cited this? | PubMed ID: 9539096 | Fulltext

Normal sperm-zona pellucida interaction and fertilization in vitro in alpha-1,3-galactosyltransferase gene knockout mice.

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Liu DY, Baker HW, Pearse MJ, and d'Apice AJ

Molecular human reproduction 3(11):1015-6, 1997 Nov - Who cited this? | PubMed ID: 9433929 | Fulltext

Combination of decay-accelerating factor expression and alpha1,3-galactosyltransferase knockout affords added protection from human complement-mediated injury.

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van Denderen BJ, Salvaris E, Romanella M, Aminian A, Katerelos M, Tange MJ, Pearse MJ, and d'Apice AJ

Transplantation 64(6):882-8, 1997 Sep 27 - Who cited this? | PubMed ID: 9326415 | Fulltext

Changes in cell surface glycosylation in alpha1,3-galactosyltransferase knockout and alpha1,2-fucosyltransferase transgenic mice.

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Shinkel TA, Chen CG, Salvaris E, Henion TR, Barlow H, Galili U, Pearse MJ, and d'Apice AJ

Transplantation 64(2):197-204, 1997 Jul 27 - Who cited this? | PubMed ID: 9256173 | Fulltext

Involvement of both the classical and alternate pathways of complement in an ex vivo model of xenograft rejection.

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Romanella M, Aminian A, Adam WR, Pearse MJ, and d'Apice AJ

Transplantation 63(7):1021-5, 1997 Apr 15 - Who cited this? | PubMed ID: 9112358 | Fulltext

Targeting gene expression to endothelial cells in transgenic mice using the human intercellular adhesion molecule 2 promoter.

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Cowan PJ, Shinkel TA, Witort EJ, Barlow H, Pearse MJ, and d'Apice AJ

Transplantation 62(2):155-60, 1996 Jul 27 - Who cited this? | PubMed ID: 8755809 | Fulltext

Two genetic approaches to the galactose alpha 1,3 galactose xenoantigen.

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d'Apice AJ, Tange MJ, Chen GC, Cowan PJ, Shinkel TA, and Pearse MJ

Transplantation proceedings 28(2):540, 1996 Apr - Who cited this? | PubMed ID: 8623255 | Fulltext

Decay-accelerating factor transgenic mouse hearts are protected from human complement-mediated attack.

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van Denderen BJ, Pearse MJ, Aminian A, Adam W, Shinkel TA, and d'Apice AJ

Transplantation proceedings 28(2):583-4, 1996 Apr - Who cited this? | PubMed ID: 8623284 | Fulltext

Mutation at ser32 of I kappa B alpha blocks NF-kappa B activation.

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Chen CG, Malliaros J, Katerelos M, d'Apice AJ, and Pearse MJ

Transplantation proceedings 28(2):615-6, 1996 Apr - Who cited this? | PubMed ID: 8623303 | Fulltext

Expression of functional decay-accelerating factor (CD55) in transgenic mice protects against human complement-mediated attack.

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van Denderen BJ, Pearse MJ, Katerelos M, Nottle MB, Du ZT, Aminian A, Adam WR, Shenoy-Scaria A, Lublin DM, Shinkel TA, and d'Apice AJ

Transplantation 61(4):582-8, 1996 Feb 27 - Who cited this? | PubMed ID: 8610385 | Fulltext

The alpha-1,3-galactosyltransferase knockout mouse. Implications for xenotransplantation.

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Tearle RG, Tange MJ, Zannettino ZL, Katerelos M, Shinkel TA, Van Denderen BJ, Lonie AJ, Lyons I, Nottle MB, Cox T, Becker C, Peura AM, Wigley PL, Crawford RJ, Robins AJ, Pearse MJ,

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Transplantation 61(1):13-9, 1996 Jan 15 - Who cited this? | PubMed ID: 8560551 | Fulltext

Inhibition of NF-kappaB activation by a dominant-negative mutant of IkappaBalpha.

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Chen CG, Malliaros J, Katerelos M, d'Apice AJ, and Pearse MJ

Molecular immunology 33(1):57-61, 1996 Jan - Who cited this? | PubMed ID: 8604224 | Fulltext

Heparin-binding epidermal growth factor-like growth factor, an immediate-early gene for mesangial cells, is up-regulated in the Thy-1.1 model.

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Polihronis M, Murphy BF, Pearse MJ, and Power DA

Experimental nephrology 4(5):271-8, 1996 - Who cited this? | PubMed ID: 8931982 | Fulltext

Functional expression of human CD59 in transgenic mice.

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Somerville CA, Kyriazis AG, McKenzie A, Allison J, Pearse MJ, and D'Apice AJ

Transplantation 58(12):1430-5, 1994 Dec 27 - Who cited this? | PubMed ID: 7528953 | Fulltext

The diagnostic use of the polymerase chain reaction for the detection of Mycobacterium tuberculosis.

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Weekes KM, Pearse MJ, Sievers A, Ross BC, and d'Apice AJ

Pathology 26(4):482-6, 1994 Oct - Who cited this? | PubMed ID: 7892054 | Fulltext

Clusterin levels increase during neuronal development.

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O'Bryan MK, Cheema SS, Bartlett PF, Murphy BF, and Pearse MJ

Journal of neurobiology 24(4):421-32, 1993 Apr - Who cited this? | PubMed ID: 8515248 | Fulltext

Essential fatty acid deficiency increases interstitial IA-positive cells in rat kidney and accelerates renal allograft rejection.

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d'Apice AJ, Kalina S, McKenzie A, Polihronis M, Eadie P, Pollock B, Pearse MJ, Sinclair AJ, and O'Brien BM

Transplantation 55(2):259-63, 1993 Feb - Who cited this? | PubMed ID: 8434373 | Fulltext

Differential expression of clusterin in inducible models of apoptosis.

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Pearse MJ, O'Bryan M, Fisicaro N, Rogers L, Murphy B, and d'Apice AJ

International immunology 4(11):1225-31, 1992 Nov - Who cited this? | PubMed ID: 1472475 | Fulltext

Endoglin: a 180-kD endothelial cell and macrophage restricted differentiation molecule.

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O'Connell PJ, McKenzie A, Fisicaro N, Rockman SP, Pearse MJ, and d'Apice AJ

Clinical and experimental immunology 90(1):154-9, 1992 Oct - Who cited this? | PubMed ID: 1395096 | Fulltext

Basic fibroblast growth factor upregulates steady-state levels of laminin B1 and B2 chain mRNA in cultured neuroepithelial cells.

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Drago J, Nurcombe V, Pearse MJ, Murphy M, and Bartlett PF

Experimental cell research 196(2):246-54, 1991 Oct - Who cited this? | PubMed ID: 1893936 | Fulltext

CD45R as a primary signal transducer stimulating IL-2 and IL-2R mRNA synthesis by CD3-4-8- thymocytes.

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Deans JP, Shaw J, Pearse MJ, and Pilarski LM

Journal of immunology (Baltimore, Md. : 1950) 143(8):2425-30, 1989 Oct 15 - Who cited this? | PubMed ID: 2477441 | Fulltext

Complete sequence of the bovine beta-lactoglobulin cDNA.

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Alexander LJ, Hayes G, Pearse MJ, Beattie CW, Stewart AF, Willis IM, and Mackinlay AG

Nucleic acids research 17(16):6739, 1989 Aug 25 - Who cited this? | PubMed ID: 2701948 | Fulltext

Efficient radioiodination and immunopurification of surface proteins from small numbers of cells.

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Pearse MJ and Gallagher PF

Immunology letters 22(1):17-21, 1989 Jul - Who cited this? | PubMed ID: 2673995 | Fulltext

Preparation of both DNA and RNA for hybridization analysis from limiting quantities of lymphoid cells.

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Pearse MJ and Wu L

Immunology letters 18(3):219-23, 1988 Jul - Who cited this? | PubMed ID: 2459054 | Fulltext

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