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Papers authored by Ostman A

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Platelet-derived growth factor receptor expression and activation in choroid plexus tumors.

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Koos B, Paulsson J, Jarvius M, Sanchez BC, Wrede B, Mertsch S, Jeibmann A, Kruse A, Peters O, Wolff JE, Galla HJ, Söderberg O, Paulus W, Ostman A, and Hasselblatt M

The American journal of pathology 175(4):1631-7, 2009 Oct - Who cited this? | PubMed ID: 19717644 | Fulltext

Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer.

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Paulsson J, Sjöblom T, Micke P, Pontén F, Landberg G, Heldin CH, Bergh J, Brennan DJ, Jirström K, and Ostman A

The American journal of pathology 175(1):334-41, 2009 Jul - Who cited this? | PubMed ID: 19498003 | Fulltext

Regulation of tyrosine phosphatases in the adventitia during vascular remodelling.

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Micke P, Hackbusch D, Mercan S, Stawowy P, Tsuprykov O, Unger T, Ostman A, and Kappert K

Biochemical and biophysical research communications 382(4):678-84, 2009 May 15 - Who cited this? | PubMed ID: 19302976 | Fulltext

CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth.

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Augsten M, Hägglöf C, Olsson E, Stolz C, Tsagozis P, Levchenko T, Frederick MJ, Borg A, Micke P, Egevad L, and Ostman A

Proceedings of the National Academy of Sciences of the United States of America 106(9):3414-9, 2009 Mar 3 - Who cited this? | PubMed ID: 19218429 | Fulltext

Metronomic scheduling of imatinib abrogates clonogenicity of neuroblastoma cells and enhances their susceptibility to selected chemotherapeutic drugs in vitro and in vivo.

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Palmberg E, Johnsen JI, Paulsson J, Gleissman H, Wickström M, Edgren M, Ostman A, Kogner P, and Lindskog M

International journal of cancer. Journal international du cancer 124(5):1227-34, 2009 Mar 1 - Who cited this? | PubMed ID: 19058199 | Fulltext

Stromal signature identifies basal breast cancers.

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Wennmalm K, Ostman A, and Bergh J

Nature medicine 15(3):237-8, 2009 Mar - Who cited this? | PubMed ID: 19265816 | Fulltext

Cancer-associated fibroblasts and tumor growth - bystanders turning into key players.

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Ostman A and Augsten M

Current opinion in genetics & development 19(1):67-73, 2009 Feb - Who cited this? | PubMed ID: 19211240 | Fulltext

The structure of the 5'-end of the protein-tyrosine phosphatase PTPRJ mRNA reveals a novel mechanism for translation attenuation.

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Karagyozov L, Godfrey R, Böhmer SA, Petermann A, Hölters S, Ostman A, and Böhmer FD

Nucleic acids research 36(13):4443, 2008 Aug - Who cited this? | PubMed ID: 18603590 | Fulltext

Redox-Sensitive Signaling by Angiotensin II Involves Oxidative Inactivation and Blunted Phosphorylation of Protein Tyrosine Phosphatase SHP-2 in Vascular Smooth Muscle Cells From SHR.

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Tabet F, Schiffrin EL, Callera G, He Y, Yao G, Ostman A, Kappert K, Tonks NK, and Touyz RM

Circulation research, 2008 Jun 19 - Who cited this? | PubMed ID: 18566342 | Fulltext

Regeneration of human epidermis on acellular dermis is impeded by small-molecule inhibitors of EGF receptor tyrosine kinase.

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Forsberg S, Ostman A, and Rollman O

Archives of dermatological research, 2008 Apr 30 - Who cited this? | PubMed ID: 18446355 | Fulltext

The effects of tumor-derived platelet-derived growth factor on vascular morphology and function in vivo revealed by susceptibility MRI.

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Robinson SP, Ludwig C, Paulsson J, and Ostman A

International journal of cancer. Journal international du cancer 122(7):1548-56, 2008 Apr 1 - Who cited this? | PubMed ID: 18033683 | Fulltext

Protein tyrosine phosphatases: regulatory mechanisms.

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den Hertog J, Ostman A, and Böhmer FD

The FEBS journal 275(5):831, 2008 Mar - Who cited this? | PubMed ID: 18298791 | Fulltext

Expression profiling of microdissected cell populations selected from basal cells in normal epidermis and basal cell carcinoma.

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Asplund A, Gry Björklund M, Sundquist C, Strömberg S, Edlund K, Ostman A, Nilsson P, Pontén F, and Lundeberg J

The British journal of dermatology 158(3):527-38, 2008 Mar - Who cited this? | PubMed ID: 18241271 | Fulltext

Platelet-derived growth factor receptor expression and amplification in choroid plexus carcinomas.

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Nupponen NN, Paulsson J, Jeibmann A, Wrede B, Tanner M, Wolff JE, Paulus W, Ostman A, and Hasselblatt M

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 21(3):265-70, 2008 Mar - Who cited this? | PubMed ID: 18157090 | Fulltext

PDGF-C is a proinflammatory cytokine that mediates renal interstitial fibrosis.

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Eitner F, Bücher E, van Roeyen C, Kunter U, Rong S, Seikrit C, Villa L, Boor P, Fredriksson L, Bäckström G, Eriksson U, Ostman A, Floege J, and Ostendorf T

Journal of the American Society of Nephrology : JASN 19(2):281-9, 2008 Feb - Who cited this? | PubMed ID: 18184860 | Fulltext

Profiling of radicular cyst and odontogenic keratocyst cytokine production suggests common growth mechanisms.

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Hayashi M, Ohshima T, Ohshima M, Yamaguchi Y, Miyata H, Takeichi O, Ogiso B, Ito K, Ostman A, and Otsuka K

Journal of endodontics 34(1):14, 2008 Jan - Who cited this? | PubMed ID: 18155485 | Fulltext

Gene expression analyses of grade II gliomas and identification of rPTP{beta}/{zeta} as a candidate oligodendroglioma marker.

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Hägerstrand D, Smits A, Eriksson A, Sigurdardottir S, Olofsson T, Hartman M, Nistér M, Kalimo H, and Ostman A

Neuro-oncology 10(1):2-9, 2008 Jan - Who cited this? | PubMed ID: 18003890 | Fulltext

Identification of a subset of pericytes that respond to combination therapy targeting PDGF and VEGF signaling.

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Hasumi Y, Kłosowska-Wardega A, Furuhashi M, Ostman A, Heldin CH, and Hellberg C

International journal of cancer. Journal international du cancer 121(12):2606-14, 2007 Dec 15 - Who cited this? | PubMed ID: 17691110 | Fulltext

In situ detection of phosphorylated platelet-derived growth factor receptor beta using a generalized proximity ligation method.

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Jarvius M, Paulsson J, Weibrecht I, Leuchowius KJ, Andersson AC, Wählby C, Gullberg M, Botling J, Sjöblom T, Markova B, Ostman A, Landegren U, and Söderberg O

Molecular & cellular proteomics : MCP 6(9):1500, 2007 Sep - Who cited this? | PubMed ID: 17565975 | Fulltext

Oxidation sensitivity of the catalytic cysteine of the protein-tyrosine phosphatases SHP-1 and SHP-2.

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Weibrecht I, Böhmer SA, Dagnell M, Kappert K, Ostman A, and Böhmer FD

Free radical biology & medicine 43(1):100-10, 2007 Jul 1 - Who cited this? | PubMed ID: 17561098 | Fulltext

In situ identification of genes regulated specifically in fibroblasts of human basal cell carcinoma.

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Micke P, Kappert K, Ohshima M, Sundquist C, Scheidl S, Lindahl P, Heldin CH, Botling J, Ponten F, and Ostman A

The Journal of investigative dermatology 127(6):1516, 2007 Jun - Who cited this? | PubMed ID: 17273163 | Fulltext

Dynamic changes in the expression of DEP-1 and other PDGF receptor-antagonizing PTPs during onset and termination of neointima formation.

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Kappert K, Paulsson J, Sparwel J, Leppänen O, Hellberg C, Ostman A, and Micke P

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 21(2):523, 2007 Feb - Who cited this? | PubMed ID: 17158785 | Fulltext

PDGF Receptors as Targets in Tumor Treatment.

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Ostman A and Heldin CH

Advances in cancer research 97:247-74, 2007 - Who cited this? | PubMed ID: 17419949 | Fulltext

Antioxidants relieve phosphatase inhibition and reduce PDGF signaling in cultured VSMCs and in restenosis.

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Kappert K, Sparwel J, Sandin A, Seiler A, Siebolts U, Leppänen O, Rosenkranz S, and Ostman A

Arteriosclerosis, thrombosis, and vascular biology 26(12):2644, 2006 Dec - Who cited this? | PubMed ID: 16990553 | Fulltext

Highly active antiretroviral therapy attenuates re-endothelialization and alters neointima formation in the rat carotid artery after balloon injury.

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Kappert K, Leppänen O, Paulsson J, Furuhashi M, Carlsson MA, Heldin CH, Fätkenheuer G, Rosenkranz S, and Ostman A

Journal of acquired immune deficiency syndromes (1999) 43(4):383-92, 2006 Dec 1 - Who cited this? | PubMed ID: 16967043 | Fulltext

Loss of T-cell protein tyrosine phosphatase induces recycling of the platelet-derived growth factor (PDGF) beta-receptor but not the PDGF alpha-receptor.

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Karlsson S, Kowanetz K, Sandin A, Persson C, Ostman A, Heldin CH, and Hellberg C

Molecular biology of the cell 17(11):4846-55, 2006 Nov - Who cited this? | PubMed ID: 16971512 | Fulltext

DEP-1 protein tyrosine phosphatase inhibits proliferation and migration of colon carcinoma cells and is upregulated by protective nutrients.

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Balavenkatraman KK, Jandt E, Friedrich K, Kautenburger T, Pool-Zobel BL, Ostman A, and Böhmer FD

Oncogene 25(47):6319-24, 2006 Oct 12 - Who cited this? | PubMed ID: 16682945 | Fulltext

Characterization of an imatinib-sensitive subset of high-grade human glioma cultures.

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Hägerstrand D, Hesselager G, Achterberg S, Wickenberg Bolin U, Kowanetz M, Kastemar M, Heldin CH, Isaksson A, Nistér M, and Ostman A

Oncogene 25(35):4913-22, 2006 Aug 10 - Who cited this? | PubMed ID: 16547494 | Fulltext

Protein-tyrosine phosphatases and cancer.

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Ostman A, Hellberg C, and Böhmer FD

Nature reviews. Cancer 6(4):307-20, 2006 Apr - Who cited this? | PubMed ID: 16557282 | Fulltext

Biobanking of fresh frozen tissue: RNA is stable in nonfixed surgical specimens.

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Micke P, Ohshima M, Tahmasebpoor S, Ren ZP, Ostman A, Pontén F, and Botling J

Laboratory investigation; a journal of technical methods and pathology 86(2):202-11, 2006 Feb - Who cited this? | PubMed ID: 16402036 | Fulltext

Exploring the tumour environment: cancer-associated fibroblasts as targets in cancer therapy.

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Micke P and Ostman A

Expert opinion on therapeutic targets 9(6):1217-33, 2005 Dec - Who cited this? | PubMed ID: 16300472 | Fulltext

Effect of platelet-derived growth factor receptor-beta inhibition with STI571 on radioimmunotherapy.

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Baranowska-Kortylewicz J, Abe M, Pietras K, Kortylewicz ZP, Kurizaki T, Nearman J, Paulsson J, Mosley RL, Enke CA, and Ostman A

Cancer research 65(17):7824-31, 2005 Sep 1 - Who cited this? | PubMed ID: 16140951 | Fulltext

Differential oxidation of protein-tyrosine phosphatases.

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Groen A, Lemeer S, van der Wijk T, Overvoorde J, Heck AJ, Ostman A, Barford D, Slijper M, and den Hertog J

The Journal of biological chemistry 280(11):10298-304, 2005 Mar 18 - Who cited this? | PubMed ID: 15623519 | Fulltext

Tyrosine phosphatases in vessel wall signaling.

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Kappert K, Peters KG, Böhmer FD, and Ostman A

Cardiovascular research 65(3):587, 2005 Feb 15 - Who cited this? | PubMed ID: 15664385 | Fulltext

An antibody-based method for monitoring in vivo oxidation of protein tyrosine phosphatases.

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Persson C, Kappert K, Engström U, Ostman A, and Sjöblom T

Methods (San Diego, Calif.) 35(1):37-43, 2005 Jan - Who cited this? | PubMed ID: 15588984 | Fulltext

Laser-assisted cell microdissection using the PALM system.

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Micke P, Ostman A, Lundeberg J, and Ponten F

Methods in molecular biology (Clifton, N.J.) 293:151-66, 2005 - Who cited this? | PubMed ID: 16028418 | Fulltext

High interstitial fluid pressure - an obstacle in cancer therapy.

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Heldin CH, Rubin K, Pietras K, and Ostman A

Nature reviews. Cancer 4(10):806-13, 2004 Oct - Who cited this? | PubMed ID: 15510161 | Fulltext

PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma.

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Ostman A

Cytokine & growth factor reviews 15(4):275-86, 2004 Aug - Who cited this? | PubMed ID: 15207817 | Fulltext

Tumour-stroma interaction: cancer-associated fibroblasts as novel targets in anti-cancer therapy?.

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Micke P and Ostman A

Lung cancer (Amsterdam, Netherlands) 45 Suppl 2:S163-75, 2004 Aug - Who cited this? | PubMed ID: 15552797 | Fulltext

c-Kit-dependent growth of uveal melanoma cells: a potential therapeutic target?.

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All-Ericsson C, Girnita L, Müller-Brunotte A, Brodin B, Seregard S, Ostman A, and Larsson O

Investigative ophthalmology & visual science 45(7):2075-82, 2004 Jul - Who cited this? | PubMed ID: 15223779 | Fulltext

Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate.

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Furuhashi M, Sjöblom T, Abramsson A, Ellingsen J, Micke P, Li H, Bergsten-Folestad E, Eriksson U, Heuchel R, Betsholtz C, Heldin CH, and Ostman A

Cancer research 64(8):2725, 2004 Apr 15 - Who cited this? | PubMed ID: 15087386 | Fulltext

Oral imatinib mesylate (STI571/gleevec) improves the efficacy of local intravascular vascular endothelial growth factor-C gene transfer in reducing neointimal growth in hypercholesterolemic rabbits.

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Leppänen O, Rutanen J, Hiltunen MO, Rissanen TT, Turunen MP, Sjöblom T, Brüggen J, Bäckström G, Carlsson M, Buchdunger E, Bergqvist D, Alitalo K, Heldin CH, Ostman A, and Ylä-Herttuala S

Circulation 109(9):1140-6, 2004 Mar 9 - Who cited this? | PubMed ID: 14769706 | Fulltext

Site-selective regulation of platelet-derived growth factor beta receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase.

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Persson C, Sävenhed C, Bourdeau A, Tremblay ML, Markova B, Böhmer FD, Haj FG, Neel BG, Elson A, Heldin CH, Rönnstrand L, Ostman A, and Hellberg C

Molecular and cellular biology 24(5):2190-201, 2004 Mar - Who cited this? | PubMed ID: 14966296 | Fulltext

Preferential oxidation of the second phosphatase domain of receptor-like PTP-alpha revealed by an antibody against oxidized protein tyrosine phosphatases.

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Persson C, Sjöblom T, Groen A, Kappert K, Engström U, Hellman U, Heldin CH, den Hertog J, and Ostman A

Proceedings of the National Academy of Sciences of the United States of America 101(7):1886-91, 2004 Feb 17 - Who cited this? | PubMed ID: 14762163 | Fulltext

A fluid cover medium provides superior morphology and preserves RNA integrity in tissue sections for laser microdissection and pressure catapulting.

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Micke P, Bjørnsen T, Scheidl S, Strömberg S, Demoulin JB, Ponten F, Ostman A, Lindahl P, and Busch C

The Journal of pathology 202(1):130-8, 2004 Jan - Who cited this? | PubMed ID: 14694530 | Fulltext

Smad2 suppresses the growth of Mv1Lu cells subcutaneously inoculated in mice.

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Sjöblom T, Yakymovych I, Heldin CH, Ostman A, and Souchelnytskyi S

European journal of cancer (Oxford, England : 1990) 40(2):267-74, 2004 Jan - Who cited this? | PubMed ID: 14728942 | Fulltext

Evaluation of environmental monitoring strategies.

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Rönnbäck BI, Nordberg ML, Olsson A, and Ostman A

Ambio 32(8):495-501, 2003 Dec - Who cited this? | PubMed ID: 15049345 | Fulltext

Two-dimensional gap analysis: a tool for efficient conservation planning and biodiversity policy implementation.

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Angelstam P, Mikusiński G, Rönnbäck BI, Ostman A, Lazdinis M, Roberge JM, Arnberg W, and Olsson J

Ambio 32(8):527-34, 2003 Dec - Who cited this? | PubMed ID: 15049349 | Fulltext

STI571 enhances the therapeutic index of epothilone B by a tumor-selective increase of drug uptake.

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Pietras K, Stumm M, Hubert M, Buchdunger E, Rubin K, Heldin CH, McSheehy P, Wartmann M, and Ostman A

Clinical cancer research : an official journal of the American Association for Cancer Research 9(10 Pt 1):3779-87, 2003 Sep 1 - Who cited this? | PubMed ID: 14506171 | Fulltext

Transgenic overexpression of platelet-derived growth factor-C in the mouse heart induces cardiac fibrosis, hypertrophy, and dilated cardiomyopathy.

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Pontén A, Li X, Thorén P, Aase K, Sjöblom T, Ostman A, and Eriksson U

The American journal of pathology 163(2):673-82, 2003 Aug - Who cited this? | PubMed ID: 12875986 | Fulltext

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Papers authored by Ostman A

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